The role of hyaluronan in wound healing

International Wound Journal - Tập 11 Số 2 - Trang 159-163 - 2014
Joseph S Frenkel1
1Wound Healing Research Unit, Department of Wound Healing, School of Medicine, Cardiff University, Melbourne, Victoria, Australia.

Tóm tắt

The polysaccharide hyaluronan (HA) (synonyms – hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's function has changed over the years, primarily focussing on a particular aspect or function. The contribution of HA in each stage of normal wound healing as well as its clinical wound dressing applications will be examined.

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