The role of dynamic conformational ensembles in biomolecular recognition

Nature Chemical Biology - Tập 5 Số 11 - Trang 789-796 - 2009
David D. Boehr1, Ruth Nussinov2,3, Peter E. Wright4
1Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania USA
2Basic Science Program, SAIC-Frederick, Inc., Center for Cancer Research Nanobiology Program, National Cancer Institute-Frederick, Frederick, USA
3Department of Human Genetics, Sackler Institute of Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
4Department of Molecular Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, USA

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