The role of cysteinyl leukotrienes in asthma: From the molecule to the bedside
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Snyder, 1989, Leukotriene receptor antagonists as potential therapeutic agents, Ann. Rev. Pharmacol. Toxicol., 29, 123, 10.1146/annurev.pa.29.040189.001011
Dahlén, 1980, Leukotrienes are potent constrictors of human bronchi, Nature, 288, 484, 10.1038/288484a0
Jones, 1982, Pharmacological study of the contractile activity of leukotriene C4 and D4 on isolated human airway smooth muscle, Can. J. Physiol. Pharmacol., 60, 638, 10.1139/y82-087
Ellis, 1994, Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi, Am. J. Respir. Crit. Care Med., 149, 118, 10.1164/ajrccm.149.1.8111568
Weiss, 1982, Bronchoconstrictor effects of leukotriene C in humans, Science, 216, 196, 10.1126/science.7063880
Weiss, 1983, Airway constriction in normal humans produced by inhalation of leukotriene D. Potency, time course, and effect of aspirin therapy, JAMA, 249, 2814, 10.1001/jama.1983.03330440052033
Davidson, 1987, Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects, Am. Rev. Respir. Dis., 135, 333
O'Hickey, 1988, The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects, Eur. Respir. J., 1, 913, 10.1183/09031936.93.01100913
Smith, 1985, The effect of inhaled leukotriene D4 in humans, Am. Rev. Respir. Dis., 131, 368
Griffin, 1983, Effects of leukotriene D on the airways in asthma, N. Engl. J. Med., 308, 436, 10.1056/NEJM198302243080807
Barnes, 1984, Actions of inhaled leukotrienes and their interactions with other allergic mediators, Prostaglandins, 28, 629, 10.1016/0090-6980(84)90137-0
Arm, 1990, Asthmatic airways have a dis-proportionate hyperresponsiveness to LTE4 as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine, Am. Rev. Respir. Dis., 142, 1112, 10.1164/ajrccm/142.5.1112
Arm, 1989, Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma, Am. Rev. Respir. Dis., 140, 148, 10.1164/ajrccm/140.1.148
Christie, 1993, Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects, Eur. Respir. J., 6, 1468, 10.1183/09031936.93.06101468
Lam, 1988, Release of leukotrienes in patients with bronchial asthma, J. Allergy Clin. Immunol., 81, 711, 10.1016/0091-6749(88)91043-3
Wardlaw, 1989, Leukotrienes, LTC, and LTB4 in bronchoalveolar lavage in bronchial asthma and other respiratory disease, J. Allergy Clin. Immunol., 84, 19, 10.1016/0091-6749(89)90173-5
Drazen, 1992, Recovery of leukotriene E4 from the urine of patients with airway obstruction, Am. Rev. Respir. Dis., 146, 104, 10.1164/ajrccm/146.1.104
Wenzel, 1990, Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge, Am. Rev. Respir. Dis., 142, 112, 10.1164/ajrccm/142.1.112
Wenzel, 1991, Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: relationship to the development of late asthmatic responses, J. Allergy Clin. Immunol., 87, 540, 10.1016/0091-6749(91)90013-E
Westcott, 1991, Urinary leukotriene E4 in patients with asthma. Effect of airways reactivity and sodium cromoglycate, Am. Rev. Respir. Dis., 143, 1322, 10.1164/ajrccm/143.6.1322
Manning, 1990, Urinary leukotriene E4 levels during early and late asthmatic responses, J. Allergy Clin. Immunol., 86, 211, 10.1016/S0091-6749(05)80068-5
Christie, 1991, Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects, Am. Rev. Respir. Dis., 143, 1025, 10.1164/ajrccm/143.5_Pt_1.1025
Fuller, 1989, Effect of the oral leukotriene D4 antagonist LY171883 on inhaled and intradermal challenge with antigen and leukotriene D4 in atopic subjects, J. Allergy Clin. Immunol., 83, 939, 10.1016/0091-6749(89)90109-7
Britton, 1987, The effect of an oral leukotriene D4 antagonist L-649,923 on the response to inhaled antigen in asthma, J. Allergy Clin. Immunol, 79, 811, 10.1016/0091-6749(87)90214-4
Taylor, 1991, Effect of cysteinyl-leukotriene receptor antagonist ICI 204,219 on allergeninduced bronchoconstriction and airway hyperreactivity in atopic subjects, Lancet, 337, 690, 10.1016/0140-6736(91)90277-V
O'Shaughnessy, 1993, Potent leukotriene D4 receptor antagonist ICI 204,219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction, Am. Rev. Respir. Dis., 147, 1431, 10.1164/ajrccm/147.6_Pt_1.1431
Findlay, 1992, Effect of the oral leukotriene antagonist, ICI 204,219, on antigen-induced bronchoconstriction in subjects with asthma, J. Allergy Clin. Immunol., 89, 1040, 10.1016/0091-6749(92)90227-S
Dahlén, 1994, The leukotriene-antagonist ICI-204,21 9 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics, Eur. Respir. J., 7, 324, 10.1183/09031936.94.07020324
Rasmussen, 1992, Leukotriene D4 receptor blockade inhibits the immediate and late bronchoconstrictor responses to inhaled antigen in patients with asthma, J. Allergy Clin. Immunol., 90, 193, 10.1016/0091-6749(92)90071-9
Robuschi, 1992, Prevention of exercise-induced bronchoconstriction by a new leukotriene antagonist (SK&F 104353). A double-blind study versus disodium cromoglycate and placebo, Am. Rev. Respir. Dis., 145, 1285, 10.1164/ajrccm/145.6.1285
Finnerty, 1992, Role of leukotrienes in exercise-induced asthma. Inhibitory effect of ICI 204,219 a potent leukotriene D4 receptor antagonist, Am. Rev. Respir. Dis., 145, 746, 10.1164/ajrccm/145.4_Pt_1.746
Makker, 1993, The protective effect of inhaled leukotriene D4 receptor antagonist ICI 204,219 against exercise-induced asthma, Am. Rev. Respir. Dis., 147, 1413, 10.1164/ajrccm/147.6_Pt_1.1413
Manning, 1990, Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist (comments) N, Engl. J. Med., 323, 1736, 10.1056/NEJM199012203232504
Christie, 1992, Effect of indo-methacin on leukotriene E4-induced histamine hyperresponsiveness in asthmatic subjects, Am. Rev. Respir. Dis., 146, 1506, 10.1164/ajrccm/146.6.1506
Kumlin, 1992, The leukotriene antagonist MK-0679 improves baseline pulmonary function and blocks aspirin-induced airways obstruction in aspirin-sensitive asthmatics (abstract), Am. Rev. Respir. Dis., 145: A15
Impens, 1993, Acute bronchodilation with an intravenously administered leukotriene D4 antagonist, MK-679, Am. Rev. Respir. Dis., 147, 1442, 10.1164/ajrccm/147.6_Pt_1.1442
Hui, 1991, Lung function improvement in asthma with a cysteinyl-leukotriene receptor antagonist, Lancet, 337, 1062, 10.1016/0140-6736(91)91709-4
Gaddy, 1992, Bronchodilation with a potent and selective leukotriene D4 (LTD4) receptor antagonist (MK-571) in patients with asthma, Am. Rev. Respir. Dis., 146, 358, 10.1164/ajrccm/146.2.358
Spector, 1992, ICI Asthma Trial Group. The effect of six weeks of therapy with oral doses of ICI 204,219 in asthmatics (abstract), Am. Rev. Respir. Dis., 145, A16
Sorkness, 1994, Bronchodilation with a selective and potent leukotriene D4 (LTD4) antagonist (MK-0476) in patients with asthma (abstract), Am. J. Respir. Crit. Care Med., 149, A216
Wahedna, 1992, Tattersfield AE. Effect of multiple doses of RG 12525, an oral leukotriene D4 antagonist, in chronic asthma (abstract), Am. Rev. Respir. Dis., 145, Al 6
Cloud, 1989, A specific LTD4/LTE4-receptor antagonist improves pulmonary function in patients with mild, chronic asthma, Am. Rev. Respir. Dis., 140, 1336, 10.1164/ajrccm/140.5.1336
Gaddy, 1991, A potent leukotriene D4 antagonist (MK-571) significantly reduces airway obstruction in mild to moderate asthma (abstract), J. Allergy Clin. Immunol., 87, A306, 10.1016/0091-6749(91)91958-V
Spector, 1994, Accolate Asthma Trialists Group. Effects of 6 weeks therapy with oral doses of ICI 204,219, a leukotriene D4 receptor antagonist in subjects with bronchial asthma, Am. J. Resp Crit. Care Med., 150, 618, 10.1164/ajrccm.150.3.8087328
Anderson, 1988, Lipoxygenase metabolites as mediators of platelet activating factor-induced increased airways responsiveness to histamine in the guinea-pig, Agents Actions Suppl., 23, 195
Christie, 1992, The effects of lipoxin A4 on airway responses in asthmatic subjects, Am. Rev. Respir. Dis., 145, 1281, 10.1164/ajrccm/145.6.1281
Hui, 1991, Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients, Thorax, 46, 184, 10.1136/thx.46.3.184
Nasser, 1994, Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses, Thorax, 49, 743, 10.1136/thx.49.8.743
Friedman, 1993, Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses, Am. Rev. Respir. Dis., 147, 839, 10.1164/ajrccm/147.4.839
Diamant, 1993, The effect of MK- 0591, a potent oral leukotriene biosynthesis inhibitor, on allergen-induced airway responses in asthmatic subjects (abstract), Am. Rev. Respir. Dis, 147, A446
Dahlen, 1993, The leukotriene biosynthesis inhibitor BAY × l005 is a potent inhibitor of allergen-induced airway obstruction and leukotriene formation in man, Pulm. Pharmacol., 6, 87
Israel, 1990, Rubin P The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air, N. Engl. J. Med., 323, 1740, 10.1056/NEJM199012203232505
Meltzer, 1994, Inhibition of exercise-induced asthma by zileuton, a 5-lipoxygenase inhibitor (abstract), Am. J. Respir. Crit. Care Med., 149, A215
Israel, 1993, The pivotal role of 5- lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin, Am. Rev. Respir. Dis., 148, 1447, 10.1164/ajrccm/148.6_Pt_1.1447
Nasser, 1994, Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma, Thorax, 49, 749, 10.1136/thx.49.8.749
Israel, 1993, The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma, Ann. Intern. Med., 119, 1059, 10.7326/0003-4819-119-11-199312010-00001
Chapman, 1994, The efficacy of an oral inhibitor of leukotriene synthesis (MK-0591) in asthmatics treated with inhaled steroids (abstract), Am. J. Respir. Crit. Care Med., 149, A215