The role of bioreactors in tissue engineering

Langer, 1993, Tissue engineering, Science, 260, 920, 10.1126/science.8493529

Butler, 2000, Functional tissue engineering: the role of biomechanics, J. Biomech. Eng., 122, 570, 10.1115/1.1318906

Mazariegos, 2002, First clinical use of a novel bioartificial liver support system (BLSS), Am. J. Transplant., 2, 260, 10.1034/j.1600-6143.2002.20311.x

Griffith, 2002, Tissue engineering – current challenges and expanding opportunities, Science, 295, 1009, 10.1126/science.1069210

Cukierman, 2001, Taking cell-matrix adhesions to the third dimension, Science, 294, 1708, 10.1126/science.1064829

Vunjak-Novakovic, 1998, Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering, Biotechnol. Prog., 14, 193, 10.1021/bp970120j

Freed, 1997, Tissue engineering of cartilage in space, Proc. Natl. Acad. Sci. U. S. A., 94, 13885, 10.1073/pnas.94.25.13885

Holy, 2000, Engineering three-dimensional bone tissue in vitro using biodegradable scaffolds: investigating initial cell-seeding density and culture period, J. Biomed. Mater. Res., 51, 376, 10.1002/1097-4636(20000905)51:3<376::AID-JBM11>3.0.CO;2-G

Carrier, 1999, Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization, Biotechnol. Bioeng., 64, 580, 10.1002/(SICI)1097-0290(19990905)64:5<580::AID-BIT8>3.0.CO;2-X

Freed, 1998, Chondrogenesis in a cell-polymer bioreactor system, Exp. Cell Res., 240, 58, 10.1006/excr.1998.4010

Ishaug-Riley, 1998, Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers, Biomaterials, 19, 1405, 10.1016/S0142-9612(98)00021-0

Kim, 1998, Optimizing seeding and culture methods to engineer smooth muscle tissue on biodegradable polymer matrices, Biotechnol. Bioeng., 57, 46, 10.1002/(SICI)1097-0290(19980105)57:1<46::AID-BIT6>3.0.CO;2-V

Bruinink, 2001, The stiffness of bone marrow cell-knit composites is increased during mechanical load, Biomaterials, 22, 3169, 10.1016/S0142-9612(01)00069-2

Li, 2001, Effects of filtration seeding on cell density, spatial distribution, and proliferation in nonwoven fibrous matrices, Biotechnol. Prog., 17, 935, 10.1021/bp0100878

Xiao, 1999, Static and dynamic fibroblast seeding and cultivation in porous PEO/PBT scaffolds, J. Mater. Sci. Mater. Med., 10, 773, 10.1023/A:1008946832443

Burg, 2002, Application of magnetic resonance microscopy to tissue engineering: a polylactide model, J. Biomed. Mater. Res., 61, 380, 10.1002/jbm.10146

Glicklis, 2000, Hepatocyte behavior within three-dimensional porous alginate scaffolds, Biotechnol. Bioeng., 67, 344, 10.1002/(SICI)1097-0290(20000205)67:3<344::AID-BIT11>3.0.CO;2-2

Nehrer, 1997, Matrix collagen type and pore size influence behaviour of seeded canine chondrocytes, Biomaterials, 18, 769, 10.1016/S0142-9612(97)00001-X

Vunjak-Novakovic, 1996, Effects of mixing on the composition and morphology of tissue-engineered cartilage, AIChE J., 42, 850, 10.1002/aic.690420323

Wendt, 2003, Oscillating perfusion of cell suspensions through three-dimensional scaffolds enhances cell seeding efficiency and uniformity, Biotechnol. Bioeng., 84, 205, 10.1002/bit.10759

Xie, 2001, Three-dimensional cell-scaffold constructs promote efficient gene transfection: implications for cell-based gene therapy, Tissue Eng., 7, 585, 10.1089/107632701753213200

Sodian, 2002, Tissue-engineering bioreactors: a new combined cell-seeding and perfusion system for vascular tissue engineering, Tissue Eng., 8, 863, 10.1089/10763270260424222

Davisson, 2002, Perfusion increases cell content and matrix synthesis in chondrocyte three-dimensional cultures, Tissue Eng., 8, 807, 10.1089/10763270260424169

Radisic, 2003, High-density seeding of myocyte cells for cardiac tissue engineering, Biotechnol. Bioeng., 82, 403, 10.1002/bit.10594

Kim, 2000, Dynamic seeding and in vitro culture of hepatocytes in a flow perfusion system, Tissue Eng., 6, 39, 10.1089/107632700320874

Sutherland, 1986, Oxygenation and differentiation in multicellular spheroids of human colon carcinoma, Cancer Res., 46, 5320

Martin, 1999, Method for quantitative analysis of glycosaminoglycan distribution in cultured natural and engineered cartilage, Ann. Biomed. Eng., 27, 656, 10.1114/1.205

Ishaug, 1997, Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds, J. Biomed. Mater. Res., 36, 17, 10.1002/(SICI)1097-4636(199707)36:1<17::AID-JBM3>3.0.CO;2-O

Gooch, 2001, Effects of mixing intensity on tissue-engineered cartilage, Biotechnol. Bioeng., 72, 402, 10.1002/1097-0290(20000220)72:4<402::AID-BIT1002>3.0.CO;2-Q

Vunjak-Novalovic, 1999, Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage, J. Orthop. Res., 17, 130, 10.1002/jor.1100170119

Rhee, 2001, Permanent phenotypic and genotypic changes of prostate cancer cells cultured in a three-dimensional rotating-wall vessel, In vitro Cell Dev. Biol. Anim., 37, 127, 10.1290/1071-2690(2001)037<0127:PPAGCO>2.0.CO;2

Licato, 2001, A novel preclinical model of human malignant melanoma utilizing bioreactor rotating-wall vessels, In vitro Cell Dev. Biol. Anim., 37, 121, 10.1290/1071-2690(2001)037<0121:ANPMOH>2.0.CO;2

Pei, 2002, Bioreactors mediate the effectiveness of tissue engineering scaffolds, FASEB J., 16, 1691, 10.1096/fj.02-0083fje

Unsworth, 1998, Growing tissues in microgravity, Nat. Med., 4, 901, 10.1038/nm0898-901

Obradovic, 2001, Integration of engineered cartilage, J. Orthop. Res., 19, 1089, 10.1016/S0736-0266(01)00030-4

Bancroft, 2002, Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner, Proc. Natl. Acad. Sci. U. S. A., 99, 12600, 10.1073/pnas.202296599

Goldstein, 2001, Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds, Biomaterials, 22, 1279, 10.1016/S0142-9612(00)00280-5

Navarro, 2001, Perfusion of medium improves growth of human oral neomucosal tissue constructs, Wound Repair Regen., 9, 507, 10.1046/j.1524-475x.2001.00507.x

Carrier, 2002, Perfusion improves tissue architecture of engineered cardiac muscle, Tissue Eng., 8, 175, 10.1089/107632702753724950

Pazzano, 2000, Comparison of chondrogenesis in static and perfused bioreactor culture, Biotechnol. Prog., 16, 893, 10.1021/bp000082v

Williams, 2002, Computational fluid dynamics modeling of steady-state momentum and mass transport in a bioreactor for cartilage tissue engineering, Biotechnol. Prog., 18, 951, 10.1021/bp020087n

Raimondi, 2002, Mechanobiology of engineered cartilage cultured under a quantified fluid-dynamic environment, Biomech. Model. Mechanobiol., 1, 69, 10.1007/s10237-002-0007-y

Risbud, 2002, Tissue engineering: advances in in vitro cartilage generation, Trends Biotechnol., 20, 351, 10.1016/S0167-7799(02)02016-4

Gomes, 2003, Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds, J. Biomed. Mater. Res., 67A, 87, 10.1002/jbm.a.10075

Zein, 2002, Fused deposition modeling of novel scaffold architectures for tissue engineering applications, Biomaterials, 23, 1169, 10.1016/S0142-9612(01)00232-0

Boland, 2003, Cell and organ printing 2: fusion of cell aggregates in three-dimensional gels, Anat. Rec., 272A, 497, 10.1002/ar.a.10059

Begley, 2000, The fluid dynamic and shear environment in the NASA/JSC rotating-wall perfused-vessel bioreactor, Biotechnol. Bioeng., 70, 32, 10.1002/1097-0290(20001005)70:1<32::AID-BIT5>3.0.CO;2-V

Sucosky, P. et al. Fluid mechanics of a spinner-flask bioreactor. Biotechnol. Bioeng. (in press).

Obradovic, 2000, Glycosaminoglycan deposition in engineered cartilage: experiments and mathematical model, AIChE J., 46, 1860, 10.1002/aic.690460914

Akhyari, 2002, Mechanical stretch regimen enhances the formation of bioengineered autologous cardiac muscle grafts, Circulation, 106, I137, 10.1161/01.cir.0000032893.55215.fc

Powell, 2002, Mechanical stimulation improves tissue-engineered human skeletal muscle, Am. J. Physiol. Cell Physiol., 283, C1557, 10.1152/ajpcell.00595.2001

Kim, 1999, Cyclic mechanical strain regulates the development of engineered smooth muscle tissue, Nat. Biotechnol., 17, 979, 10.1038/13671

Niklason, 1999, Functional arteries grown in vitro, Science, 284, 489, 10.1126/science.284.5413.489

Davisson, 2002, Static and dynamic compression modulate matrix metabolism in tissue engineered cartilage, J. Orthop. Res., 20, 842, 10.1016/S0736-0266(01)00160-7

Waldman, 2003, Effect of biomechanical conditioning on cartilaginous tissue formation in vitro, J. Bone Jt Surg. Am., 85A, 101, 10.2106/00004623-200300002-00013

Mauck, 2000, Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels, J. Biomech. Eng., 122, 252, 10.1115/1.429656

Altman, 2002, Cell differentiation by mechanical stress, FASEB J., 16, 270, 10.1096/fj.01-0656fje

Démarteau, 2003, Development and validation of a bioreactor for physical stimulation of engineered cartilage, Biorheology, 40, 331

Démarteau, 2003, Dynamic compression of cartilage constructs engineered from expanded human articular chondrocytes, Biochem. Biophys. Res. Commun., 310, 580, 10.1016/j.bbrc.2003.09.099

Ratcliffe, 2002, Bioreactors and bioprocessing for tissue engineering, Ann. New York Acad. Sci., 961, 210, 10.1111/j.1749-6632.2002.tb03087.x

Leventon, 2002, Synthetic skin, IEEE Spectr., 39, 28, 10.1109/MSPEC.2002.1088442

Naughton, 2002, From lab bench to market: critical issues in tissue engineering, Ann. New York Acad. Sci., 961, 372, 10.1111/j.1749-6632.2002.tb03127.x

Cabrita, 2003, Hematopoietic stem cells: from the bone to the bioreactor, Trends Biotechnol., 21, 233, 10.1016/S0167-7799(03)00076-3

Jasmund, 2002, Bioreactor developments for tissue engineering applications by the example of the bioartificial liver, Adv. Biochem. Eng. Biotechnol., 74, 99

Martin, 2000, Modulation of the mechanical properties of tissue-engineered cartilage, Biorheology, 37, 141