The role of SMC proteins in the responses to DNA damage

Strunnikov, 1993, SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family, J. Cell Biol., 123 Hirano, 2000, Chromosome cohesion, condensation, and separation, Annu. Rev. Biochem., 69, 115, 10.1146/annurev.biochem.69.1.115 Hirano, 2002, The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair, Genes Dev., 16, 399, 10.1101/gad.955102 Jessberger, 2002, The many functions of SMC proteins in chromosome dynamics, Nat. Rev. Mol. Cell Biol., 3, 767, 10.1038/nrm930 Yokomori, 2003, SMC protein complexes and the maintenance of chromosome integrity, Curr. Top. Microbiol. Immunol., 274, 79 Cobbe, 2004, The evolution of SMC proteins: phylogenetic analysis and structural implications, Mol. Biol. Evol., 21, 332, 10.1093/molbev/msh023 Gruber, 2003, Chromosomal cohesin forms a ring, Cell, 112, 765, 10.1016/S0092-8674(03)00162-4 Arumugam, 2003, ATP hydrolysis is required for cohesin's association with chromosomes, Curr. Biol., 13, 1941, 10.1016/j.cub.2003.10.036 Weitzer, 2003, A model for ATP hydrolysis-dependent binding of cohesin to DNA, Curr. Biol., 13 Uhlmann, 2000, Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast, Cell, 103 Phipps, 1985, Recovery, repair and mutagenesis in Schizosaccharomyces pombe, Adv. Genet., 23, 1, 10.1016/S0065-2660(08)60511-8 Birkenbihl, 1992, Cloning and characterisation of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair, Nucl. Acids Res., 20, 6605, 10.1093/nar/20.24.6605 Tatebayashi, 1998, Isolation of a Schizosaccharomyces pombe rad21ts mutant that is aberrant in chromosome segregation, microtubule function, DNA repair and sensitive to hydroxyurea: possible involvement of Rad21 in ubiquitin-mediated proteolysis, Genetics, 148, 49, 10.1093/genetics/148.1.49 Sjogren, 2001, Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae, Curr. Biol., 11, 991, 10.1016/S0960-9822(01)00271-8 Skibbens, 1999, Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery, Genes Dev., 13, 307, 10.1101/gad.13.3.307 Toth, 1999, Yeast cohesin complex requires a conserved protein, Eco1p (Ctf7), to establish cohesion between sister chromatids during DNA replication, Genes Dev., 13, 320, 10.1101/gad.13.3.320 Sonoda, 2001, Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells, Dev. Cell, 1, 759, 10.1016/S1534-5807(01)00088-0 Kim, 2002, Specific recruitment of human cohesin to laser-induced DNA damage, J. Biol. Chem., 277, 45149, 10.1074/jbc.M209123200 Abraham, 2001, Cell cycle checkpoint signaling through the ATM and ATR kinases, Genes Dev., 15, 2177, 10.1101/gad.914401 Nelms, 1998, In situ visualization of DNA double-strand break repair in human fibroblasts, Science, 280, 590, 10.1126/science.280.5363.590 Kim, 2002, Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage, Genes Dev., 16, 560, 10.1101/gad.970602 Yazdi, 2002, SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint, Genes Dev., 16, 571, 10.1101/gad.970702 Kitagawa, 2004, Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway, Genes Dev., 1423, 10.1101/gad.1200304 Kimura, 1997, ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation, Cell, 90, 625, 10.1016/S0092-8674(00)80524-3 Aono, 2002, Cnd2 has dual roles in mitotic condensation and interphase, Nature, 417, 197, 10.1038/417197a Chen, 2004, Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin, Proc. Natl. Acad. Sci. U.S.A., 101, 8078, 10.1073/pnas.0307976101 Nasim, 1975, Genetic control of radiation sensitivity in Schizosaccharomyces pombe, Genetics, 79, 573, 10.1093/genetics/79.4.573 Lehmann, 1995, The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair, Mol. Cell. Biol., 15, 7067, 10.1128/MCB.15.12.7067 Verkade, 1999, Rad18 is required for DNA repair and checkpoint responses in fission yeast, Mol. Biol. Cell, 10, 2905, 10.1091/mbc.10.9.2905 Harvey, 2004, Coordination of DNA damage responses via the Smc5/Smc6 complex, Mol. Cell Biol., 24, 662, 10.1128/MCB.24.2.662-674.2004 Fousteri, 2000, A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein, EMBO J., 19, 1691, 10.1093/emboj/19.7.1691 Fujioka, 2002, Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5–SMC6 complex involved in DNA repair, J. Biol. Chem., 277, 21585, 10.1074/jbc.M201523200 McDonald, 2003, Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5–Smc6 complex, J. Biol. Chem., 278, 45460, 10.1074/jbc.M308828200 Hazbun, 2003, Assigning function to yeast proteins by integration of technologies, Mol. Cell, 12, 1353, 10.1016/S1097-2765(03)00476-3 H. Morikawa, T. Morishita, S. Kawane, H. Iwasaki, A.M. Carr, H. Shinagawa, Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast, Mol. Cell. Biol. 2004, in press. Onoda, 2004, SMC6 is required for MMS-induced interchromosomal and sister chromatid recombinations in Saccharomyces cerevisiae, DNA Repair (Amst), 3, 429, 10.1016/j.dnarep.2003.12.007 Mengiste, 1999, An SMC-like protein is required for efficient homologous recombination in Arabidopsis, EMBO J., 18, 4505, 10.1093/emboj/18.16.4505 Taylor, 2001, Characterisation of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex, Mol. Biol. Cell., 12, 1583, 10.1091/mbc.12.6.1583 Hopfner, 2000, Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily, Cell, 101, 789, 10.1016/S0092-8674(00)80890-9 Hopfner, 2002, The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair, Nature, 418, 562, 10.1038/nature00922