The role of SDF-1/CXCR4 axis in ovarian cancer metastasis

Balkwill F. The significance of cancer cell expression of the chemokine receptor CXCR4. Semin Cancer Biol, 2004,14(3):171–179

Grunewald M, Avraham I, Dor Y, et al. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell, 2006,124(1):175–189

Katayama Y, Battista M, Kao WM, et al. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell, 2006,124(2):407–421

Zou YR, Kottmann AH, Kuroda M, et al. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature, 1998,393(6685):595–599

Begley LA, MacDonald JW, Day ML, et al. CXCL12 activates a robust transcriptional response in human prostate epithelial cells. J Biol Chem, 2007,282(37): 26767–2674

Kucia M, Jankowski K, Reca R, et al. CXCR4-SDF-1 signaling, locomotion, chemotaxis and adhesion. J Mol Histol, 2004,35(3):233–245

Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature, 2001,410(6824):50–56

Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell, 2005,121(3):335–348

Marchesi F, Monti P, Leone BE, et al. Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4. Cancer Res, 2004,64(22):8420–8427

Scotton CJ, Wilson JL, Milliken D, et al. Epithelial cancer cell migration: a role for chemokine receptors? Cancer Res, 2001,61(13):4961–4965

Scotton CJ, Wilson JL, Scott K, et al. Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res, 2002,62(20):5930–5938

Porcile C, Bajetto A, Barbieri F, et al. Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. Exp Cell Res, 2005,08(2):241–253

Zlotnik A. Chemokines in neoplastic progression. Semin Cancer Biol, 2004,14(3):181–185

Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer, 2002,2(8):563–572

Christopherson KW II, Hangoc G, Mantel CR, et al. Modulation of hematopoietic stem cell homing and engraftment by CD26. Science, 2004,305(5686):1000–1003

Chung LW. Prostate carcinoma bone-stroma interaction and its biologic and therapeutic implications. Cancer, 2003, 97(3):772–778

Kryczek I, Lange A, Mottram P, et al. CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res, 2005,65(2):465–472

Jiang YP, Wu XH, Shi B, et al. Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression. Gynecol Oncol, 2006,103(1):226–233

Peled, A, Grabovsky V, Habler L, et al. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34 (+) cells on vascular endothelium under shear flow. J Clin Invest, 1999,104(9):1199–1211

Murakami T, Maki W, Cardones AR, et al. Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells. Cancer Res, 2002,62(24): 7328–7334

Brand S, Dambacher J, Beigel F, et al. CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res, 2005,310(1):117–130

Uchida D, Begum NM, Almofti A, et al. Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma. Exp Cell Res, 2003,290(2):289–302

Yu X, Huang Y, Collin-Osdoby P, et al. Stromal cell-derived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration. J Bone Miner Res, 2003,18(8):1404–1418