The role of FOXP3 in non-small cell lung cancer and its therapeutic potentials
Tài liệu tham khảo
Aarts-Riemens, 2008, Forced overexpression of either of the two common human Foxp3 isoforms can induce regulatory T cells from CD4(+)CD25(−) cells, European Journal of Immunology, 38, 1381, 10.1002/eji.200737590
Antonoff, 2022, The roles of surgery, stereotactic radiation, and ablation for treatment of pulmonary metastases, The Journal of Thoracic and Cardiovascular Surgery, 163, 495, 10.1016/j.jtcvs.2021.01.143
Arbour, 2019, Systemic therapy for locally advanced and metastatic non-small cell lung cancer: A review, JAMA, 322, 764, 10.1001/jama.2019.11058
Bacchetta, 2018, From IPEX syndrome to FOXP3 mutation: A lesson on immune dysregulation, Annals of the New York Academy of Sciences, 1417, 5, 10.1111/nyas.13011
Bernard, 2022, Alternative splicing in cancer and immune cells, Cancers, 14, 1726, 10.3390/cancers14071726
Bora-Singhal, 2015, Gli1-mediated regulation of Sox2 facilitates self-renewal of stem-like cells and confers resistance to EGFR inhibitors in non-small cell lung cancer, Neoplasia (New York, N.Y.), 17, 538, 10.1016/j.neo.2015.07.001
Bu, 2020, Expression profile of GINS complex predicts the prognosis of pancreatic cancer patients, Oncotargets and Therapy, 13, 11433, 10.2147/OTT.S275649
Bushweller, 2019, Targeting transcription factors in cancer - from undruggable to reality, Nature Reviews. Cancer, 19, 611, 10.1038/s41568-019-0196-7
Carneiro, 2020, Targeting apoptosis in cancer therapy, Nature Reviews. Clinical Oncology, 17, 395, 10.1038/s41571-020-0341-y
Chamberlain, 2017, Systemic therapy of brain metastases: Non-small cell lung cancer, breast cancer, and melanoma, Neuro-Oncology, 19, i1, 10.1093/neuonc/now197
Charbonnier, 2019, Functional reprogramming of regulatory T cells in the absence of Foxp3, Nature Immunology, 20, 1208, 10.1038/s41590-019-0442-x
Chi, 2019, Long non-coding RNA in the pathogenesis of cancers, Cells, 8, 1015, 10.3390/cells8091015
Choi, 2019, Pulsatile MEK inhibition improves anti-tumor immunity and T cell function in murine Kras mutant lung cancer, Cell Reports, 27, 806, 10.1016/j.celrep.2019.03.066
Deng, 2020, Foxp3 in Treg cell biology: A molecular and structural perspective, Clinical and Experimental Immunology, 199, 255, 10.1111/cei.13357
Dong, 2021, Post-translational regulations of Foxp3 in Treg cells and their therapeutic applications, Frontiers in Immunology, 12, 10.3389/fimmu.2021.626172
Duma, 2019, Non-small cell lung cancer: Epidemiology, screening, diagnosis, and treatment, Mayo Clinic Proceedings, 94, 1623, 10.1016/j.mayocp.2019.01.013
Ebert, 2003, Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer, The Oncologist, 8, 69, 10.1634/theoncologist.8-1-69
Ebert, 2008, The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells, Cancer Research, 68, 3001, 10.1158/0008-5472.CAN-07-5664
Esteller, 2011, Non-coding RNAs in human disease, Nature Reviews. Genetics, 12, 861, 10.1038/nrg3074
Fleskens, 2019, Nemo-like kinase drives Foxp3 stability and is critical for maintenance of immune tolerance by regulatory T cells, Cell Reports, 26, 3600, 10.1016/j.celrep.2019.02.087
Floess, 2007, Epigenetic control of the foxp3 locus in regulatory T cells, PLoS Biology, 5, 10.1371/journal.pbio.0050038
Fu, 2013, Foxp3 and TLR4 protein expression are correlated in non-small cell lung cancer: Implications for tumor progression and escape, Acta Histochemica, 115, 151, 10.1016/j.acthis.2012.06.002
Galeaz, 2021, Radiation resistance: A matter of transcription factors, Frontiers in Oncology, 11, 10.3389/fonc.2021.662840
Gao, 2020, Fut4sirna augments the chemosensitivity of non-small cell lung cancer to cisplatin through activation of FOXO1-induced apoptosis, BMC Cancer, 20, 895, 10.1186/s12885-020-07324-z
Gao, 2018, Foxo1 inhibits tumor cell migration via regulating cell surface morphology in non-small cell lung cancer cells, Cellular Physiology and Biochemistry, 48, 138, 10.1159/000491670
Gerdes, 1984, Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67, Journal of Immunology (Baltimore, Md. : 1950), 133, 1710
Giatromanolaki, 2019, Foxp3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma, Experimental Lung Research, 45, 76, 10.1080/01902148.2019.1617371
de Gregorio, 2021, Ki67 as proliferative marker in patients with early breast cancer and its association with clinicopathological factors, Oncology, 99, 780, 10.1159/000517490
Hammarsten, 2019, Immunoreactivity for prostate specific antigen and Ki67 differentiates subgroups of prostate cancer related to outcome, Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc, 32, 1310, 10.1038/s41379-019-0260-6
Harrison, 2020, Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer, Seminars in Cancer Biology, 61, 167, 10.1016/j.semcancer.2019.09.015
Hayatsu, 2017, Analyses of a mutant Foxp3 allele reveal BATF as a critical transcription factor in the differentiation and accumulation of tissue regulatory T cells, Immunity, 47, 268, 10.1016/j.immuni.2017.07.008
He, 2013, Foxp3 genetic variants and risk of non-small cell lung cancer in the Chinese Han population, Gene, 531, 422, 10.1016/j.gene.2013.08.066
Herbst, 2018, The biology and management of non-small cell lung cancer, Nature, 553, 446, 10.1038/nature25183
Herman, 2021, Forkhead Transcription Factors in Health and Disease, Trends in Genetics: TIG, 37, 460, 10.1016/j.tig.2020.11.003
Hori, 2003, Control of regulatory T cell development by the transcription factor Foxp3, Science (New York, N.Y.), 299, 1057, 10.1126/science.1079490
Huang, 2020, A positive feedback loop formed by NGFR and FOXP3 contributes to the resistance of non-small cell lung cancer to icotinib, Translational Cancer Research, 9, 1044, 10.21037/tcr.2019.12.60
Jia, 2019, The expression of FOXP3 and its role in human cancers, Biochimica Et Biophysica Acta. Reviews on Cancer, 1871, 170, 10.1016/j.bbcan.2018.12.004
Jia, 2012, Foxp3 expression in A549 cells is regulated by toll-like receptor 4 through nuclear factor-κB, Molecular Medicine Reports, 6, 167
Joly, 2019, Alternative splicing, FOXP3 and cardiovascular disease, Aging, 11, 1905, 10.18632/aging.101897
Katoh, 2010, Signalling through FOXP3 as an X-linked tumor suppressor, The International Journal of Biochemistry & Cell Biology, 42, 1784, 10.1016/j.biocel.2010.07.015
Ke, 2016, Non-small-cell lung cancer-induced immunosuppression by increased human regulatory T cells via Foxp3 promoter demethylation, Cancer Immunology, Immunotherapy, 65, 587, 10.1007/s00262-016-1825-6
Koh, 2020, Regulatory (FoxP3+) T cells and TGF-β predict the response to anti-PD-1 immunotherapy in patients with non-small cell lung cancer, Scientific Reports, 10, 18994, 10.1038/s41598-020-76130-1
Kondo, 2005, The role of autophagy in cancer development and response to therapy, Nature Reviews. Cancer, 5, 726, 10.1038/nrc1692
Lambert, 2018, Targeting transcription factors for cancer treatment, Molecules (Basel, Switzerland), 23, 10.3390/molecules23061479
Lamberti, 2020, Beyond EGFR, ALK and ROS1: Current evidence and future perspectives on newly targetable oncogenic drivers in lung adenocarcinoma, Critical Reviews in Oncology/Hematology, 156, 10.1016/j.critrevonc.2020.103119
Li, 2017, Downregulation of FOXP3 inhibits cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma, Pathology, Research and Practice, 213, 1251, 10.1016/j.prp.2017.09.004
Li, 2021, Foxp3 facilitates the invasion and metastasis of non-small cell lung cancer cells through regulating VEGF, EMT and the Notch1/Hes1 pathway, Experimental and Therapeutic Medicine, 22, 958, 10.3892/etm.2021.10390
Li, 2012, Foxp3 overexpression decreases sensitivity to chemotherapy in mouse Lewis lung cancer cells, Molecular Medicine Reports, 6, 977, 10.3892/mmr.2012.1066
Li, 2021, Expression and prognosis analysis of GINS subunits in human breast cancer, Medicine, 100, 10.1097/MD.0000000000024827
Li, 2021, Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation, Cell Reports, 37, 10.1016/j.celrep.2021.110124
Li, 2018, Role of transcription factor FOXA1 in non-small cell lung cancer, Molecular Medicine Reports, 17, 509, 10.3892/mmr.2014.2680
Li, 2021, Malat1 modulated FOXP3 ubiquitination then affected GINS1 transcription and drived NSCLC proliferation, Oncogene, 40, 3870, 10.1038/s41388-021-01816-3
Li, 2021, Gins1 induced sorafenib resistance by promoting cancer stem properties in human hepatocellular cancer cells, Frontiers in Cell and Development Biology, 9
Li, 2016, Overexpression of the transcription factor FOXP3 in lung adenocarcinoma sustains malignant character by promoting G1/S transition gene CCND1, Tumour Biology : The Journal of the International Society for Oncodevelopmental Biology and Medicine, 37, 7395, 10.1007/s13277-015-4616-3
Liang, 2022, Foxp3 contributes to TMZ resistance, prognosis, and immune infiltration in GBM from a novel pyroptosis-associated risk signature, Disease Markers, 2022, 4534080, 10.1155/2022/4534080
Liu, 2019, Oxymatrine-mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin-resistance in lung cancer cells, Molecular Medicine Reports, 19, 4081
Liu, 2021, Pd-1/PD-L1 checkpoint inhibitors in tumor immunotherapy, Frontiers in Pharmacology, 12
Liu, 2020, Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer, The Journal of Clinical Investigation, 130, 2081, 10.1172/JCI131335
Liu, 2019, Epigenetic control of Foxp3 in intratumoral T-cells regulates growth of hepatocellular carcinoma, Aging, 11, 2343, 10.18632/aging.101918
Liu, 2012, Inactivation of X-linked tumor suppressor genes in human cancer, Future Oncology (London, England), 8, 463, 10.2217/fon.12.26
Lozano, 2013, Searching for the achilles heel of FOXP3, Frontiers in Oncology, 3, 294, 10.3389/fonc.2013.00294
Lu, 2017, The regulation of immune tolerance by FOXP3, Nature Reviews. Immunology, 17, 703, 10.1038/nri.2017.75
Lv, 2018, Gli1, a potential cancer stem cell marker, is strongly associated with prognosis in prostate cancer, International Journal of Clinical and Experimental Pathology, 11, 4957
Ma, 2021, The efficacy and possible mechanisms of immune checkpoint inhibitors in treating non-small cell lung cancer patients with epidermal growth factor receptor mutation, Cancer Communications, 41, 1314, 10.1002/cac2.12229
Magg, 2018, Ipex due to an exon 7 skipping FOXP3 mutation with autoimmune diabetes mellitus cured by selective TReg cell engraftment, Clinical Immunology (Orlando, Fla.), 191, 52, 10.1016/j.clim.2018.03.008
Mailer, 2018, Alternative splicing of FOXP3-virtue and vice, Frontiers in Immunology, 9, 530, 10.3389/fimmu.2018.00530
Mailer, 2009, Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity, PLoS One, 4, 10.1371/journal.pone.0006104
Miller, 2021, Advances in systemic therapy for non-small cell lung cancer, BMJ (Clinical Research Ed.), 375
Peng, 2018, The effect of foxp3-overexpressing Treg cells on non-small cell lung cancer cells, Molecular Medicine Reports, 17, 5860
Phelps, 2018, Roles of thyroid transcription factor 1 in lung cancer biology, Vitamins and Hormones, 106, 517, 10.1016/bs.vh.2017.05.007
Placek, 2017, Mll4 prepares the enhancer landscape for Foxp3 induction via chromatin looping, Nature Immunology, 18, 1035, 10.1038/ni.3812
Polansky, 2008, Dna methylation controls Foxp3 gene expression, European Journal of Immunology, 38, 1654, 10.1002/eji.200838105
Pu, 2022, Transient receptor potential vanilloid 4 promotes the growth of non-small cell lung cancer by regulating Foxp3, Acta Biochimica Polonica, 69, 51
Qi, 2020, Glioma-associated oncogene homolog 1 stimulates FOXP3 to promote non-small cell lung cancer stemness, American Journal of Translational Research, 12, 1839
Qi, 2019, Egfr-AS1/HIF2A regulates the expression of FOXP3 to impact the cancer stemness of smoking-related non-small cell lung cancer, Therapeutic Advances in Medical Oncology, 11, 10.1177/1758835919855228
Reita, 2022, Direct targeting KRAS mutation in non-small cell lung cancer: Focus on resistance, Cancers, 14, 10.3390/cancers14051321
Scagliotti, 2017, Lung cancer: Current therapies and new targeted treatments, The Lancet, 389, 299, 10.1016/S0140-6736(16)30958-8
Shi, 2017, Foxp3 is a HCC suppressor gene and acts through regulating the TGF-β/Smad2/3 signaling pathway, BMC Cancer, 17, 648, 10.1186/s12885-017-3633-6
Shimizu, 2010, Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer, Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer, 5, 585, 10.1097/JTO.0b013e3181d60fd7
Siegel, 2021, Cancer statistics, 2021, CA: a Cancer Journal for Clinicians, 71, 7
Siegel, 2022, Cancer statistics, 2022, CA: a Cancer Journal for Clinicians, 72, 7
Song, 2021, Clinical significance of circulating tumour cells and Ki-67 in renal cell carcinoma, World Journal of Surgical Oncology, 19, 156, 10.1186/s12957-021-02268-5
Sugiyama, 2020, Blockade of EGFR improves responsiveness to PD-1 blockade in EGFR-mutated non-small cell lung cancer, Science Immunology, 5, 10.1126/sciimmunol.aav3937
Sung, 2021, Global cancer statistics 2020: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA: a Cancer Journal for Clinicians, 71, 209
Tao, 2017, Foxp3, regulatory T cell, and autoimmune diseases, Inflammation, 40, 328, 10.1007/s10753-016-0470-8
Thai, 2021, Lung cancer, The Lancet, 398, 535, 10.1016/S0140-6736(21)00312-3
Triulzi, 2013, Foxp3 expression in tumor cells and implications for cancer progression, Journal of Cellular Physiology, 228, 30, 10.1002/jcp.24125
Velut, 2022, Smarca4-deficient lung carcinoma is an aggressive tumor highly infiltrated by FOXP3+ cells and neutrophils, Lung Cancer (Amsterdam, Netherlands), 169, 13, 10.1016/j.lungcan.2022.05.001
Wang, 2021, Forkhead box protein P3 (FOXP3) represses ATF3 transcriptional activity, International Journal of Molecular Sciences, 22, 10.3390/ijms222111400
Wang, 2018, Foxp3 activates SUMO-conjugating UBC9 gene in MCF7 breast cancer cells, International Journal of Molecular Sciences, 19, 10.3390/ijms19072036
Wang, 2018, Members of FOX family could be drug targets of cancers, Pharmacology & Therapeutics, 181, 183, 10.1016/j.pharmthera.2017.08.003
Wang, 2019, Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA, Cell Death and Differentiation, 26, 2329, 10.1038/s41418-019-0304-y
Wang, 2018, Microrna-125b interacts with Foxp3 to induce autophagy in thyroid cancer, Molecular Therapy : The Journal of the American Society of Gene Therapy, 26, 2295, 10.1016/j.ymthe.2018.06.015
Won, 2020, Hippo pathway and tumoral FOXP3 expression correlate with tumor growth in squamous cell carcinoma of the lung, Pathology, Research and Practice, 216, 10.1016/j.prp.2020.153003
Wu, 2021, Expression and prognostic value of E2F3 transcription factor in non-small cell lung cancer, Oncology Letters, 21, 411, 10.3892/ol.2021.12672
Xu, 2021, Cochlioquinone derivative CoB1 induces cytostatic autophagy in lung cancer through miRNA-125b and Foxp3, Phytomedicine : International Journal of Phytotherapy and Phytopharmacology, 93, 10.1016/j.phymed.2021.153742
Yang, 2017, Foxp3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer, Molecular Cancer, 16, 124, 10.1186/s12943-017-0700-1
Ye, 2018, Oxymatrine and cisplatin synergistically enhance anti-tumor immunity of CD8+ T cells in non-small cell lung cancer, Frontiers in Oncology, 8, 631, 10.3389/fonc.2018.00631
Yin, 2020, Ube2t promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation, Cancer Letters, 494, 121, 10.1016/j.canlet.2020.06.005
Yochum, 2019, Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer, Oncogene, 38, 656, 10.1038/s41388-018-0482-y
Zhang, 2016, Biased expression of the FOXP3Δ3 isoform in aggressive bladder cancer mediates differentiation and cisplatin chemotherapy resistance, Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 22, 5349, 10.1158/1078-0432.CCR-15-2581
Zhang, 2021, Chemical molecular-based approach to overcome multidrug resistance in cancer by targeting P-glycoprotein (P-gp), Medicinal Research Reviews, 41, 525, 10.1002/med.21739
Zhao, 2020, Chemotherapy exacerbates ovarian cancer cell migration and cancer stem cell-like characteristics through GLI1, British Journal of Cancer, 122, 1638, 10.1038/s41416-020-0825-7
Zhu, 2022, Foxp3 activated-LINC01232 accelerates the stemness of non-small cell lung carcinoma by activating TGF-β signaling pathway and recruiting IGF2BP2 to stabilize TGFBR1, Experimental Cell Research, 413, 10.1016/j.yexcr.2022.113024
Zhu, 2018, Effectiveness of temozolomide combined with whole brain radiotherapy for non-small cell lung cancer brain metastases, Thoracic Cancer, 9, 1121, 10.1111/1759-7714.12795
Zuo, 2007, Foxp3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene, Cell, 129, 1275, 10.1016/j.cell.2007.04.034