The relationship between hypoxia-inducible factor 1α (HIF-1α) and patient survival in breast cancer: Systematic review and meta-analysis

Critical Reviews in Oncology/Hematology - Tập 159 - Trang 103231 - 2021
Suad A.K. Shamis1,2, Donald C. McMillan1, Joanne Edwards2
1Academic Unit of Surgery, College of Medical, Veterinary and Life Sciences- University of Glasgow, Royal Infirmary, Glasgow, UK
2Unit of Experimental Therapeutics, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences-University of Glasgow, Glasgow, UK

Tài liệu tham khảo

Bos, 2003, Levels of hypoxia‐inducible factor‐1α independently predict prognosis in patients with lymph node negative breast carcinoma, Cancer: Interdiscip. Int. J. Am. Cancer Soc., 97, 1573, 10.1002/cncr.11246 Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 68, 394, 10.3322/caac.21492 Cai, 2016, Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer, Oncotarget, 7, 77793, 10.18632/oncotarget.12796 Chen, 2007, Hypoxia-inducible factor-1α correlates with MET and metastasis in node-negative breast cancer, Breast Cancer Res. Treat., 103, 167, 10.1007/s10549-006-9360-3 Chen, 2012, Over-expression of semaphorin4D, hypoxia-inducible factor-1α and vascular endothelial growth factor is related to poor prognosis in ovarian epithelial cancer, Int. J. Mol. Sci., 13, 13264, 10.3390/ijms131013264 Choi, 2013, Metabolism-related proteins are differentially expressed according to the molecular subtype of invasive breast cancer defined by surrogate immunohistochemistry, Pathobiology, 80, 41, 10.1159/000339513 Cui, 2019 Dai, 2009, Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery, BMC Cancer, 9, 418, 10.1186/1471-2407-9-418 Dales, 2005, Overexpression of hypoxia‐inducible factor HIF‐1α predicts early relapse in breast cancer: retrospective study in a series of 745 patients, Int. J. Cancer, 116, 734, 10.1002/ijc.20984 Dong, 2013, Low expression of Beclin 1 and elevated expression of HIF-1α refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer, Med. Oncol., 30, 355, 10.1007/s12032-012-0355-0 Erpolat, 2013, Hypoxia-related molecules HIF-1α, CA9, and osteopontin, Strahlenther. Und Onkol., 189, 147, 10.1007/s00066-012-0262-5 Generali, 2006, Hypoxia-inducible factor-1α expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer, Clin. Cancer Res., 12, 4562, 10.1158/1078-0432.CCR-05-2690 Giatromanolaki, 2004, c-erbB-2 related aggressiveness in breast cancer is hypoxia inducible factor-1α dependent, Clin. Cancer Res., 10, 7972, 10.1158/1078-0432.CCR-04-1068 Grassadonia, 2017, Long-term outcome of breast cancer patients with pathologic N3a lymph node stage, Breast, 32, 79, 10.1016/j.breast.2016.12.018 Gruber, 2004, Hypoxia- inducible factor 1 alpha in high-risk breast cancer: an independent prognostic parameter?, Breast Cancer Res., 6, R191, 10.1186/bcr775 Higgins, 2003, Measuring inconsistency in meta-analyses, Bmj, 327, 557, 10.1136/bmj.327.7414.557 Huang, 2014, SNP 1772 C& T of HIF-1α gene associates with breast cancer risk in a Taiwanese population, Cancer Cell Int., 14, 1, 10.1186/s12935-014-0087-7 Jemal, 2011, Global cancer statistics, CA Cancer J. Clin., 61, 69, 10.3322/caac.20107 Jin, 2016, Overexpression of HIF1α and CAXI predicts poor outcome in early-stage triple negative breast cancer, Virchows Arch., 469, 183, 10.1007/s00428-016-1953-6 Jing, 2019, Role of hypoxia in cancer therapy by regulating the tumor microenvironment, Mol. Cancer, 18, 157, 10.1186/s12943-019-1089-9 Jögi, 2019, Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer, PLoS One, 14, e0226150, 10.1371/journal.pone.0226150 Kalemkerian, 2018, J. Clin. Oncol.: Off. J. Am. Soc. Clin. Oncol., 36, 911, 10.1200/JCO.2017.76.7293 Kasangian, 2017, The prognostic role of tumor size in early breast cancer in the era of molecular biology, PLoS One, 12, e0189127, 10.1371/journal.pone.0189127 Keith, 2012, HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression, Nat. Rev. Cancer, 12, 9, 10.1038/nrc3183 Koo, 2010, Alteration of REDD1-mediated mammalian target of rapamycin pathway and hypoxia-inducible factor-1α regulation in human breast cancer, Pathobiology, 77, 289, 10.1159/000320936 Kronblad, 2006, Hypoxia inducible factor‐1α is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response, Int. J. Cancer, 118, 2609, 10.1002/ijc.21676 Laurinavicius, 2015, Ki67/SATB1 ratio is an independent prognostic factor of overall survival in patients with early hormone receptor-positive invasive ductal breast carcinoma, Oncotarget, 6, 41134, 10.18632/oncotarget.5838 Lee, 2012, Hypoxia-inducible factor-1α and excision repair cross-complementing 1 in patients with small cell lung cancer who received front-line platinum-based chemotherapy: a retrospective study, J. Thorac. Oncol., 7, 528, 10.1097/JTO.0b013e3182417830 Li, 2016, Expression of LPA2 is associated with poor prognosis in human breast cancer and regulates HIF-1α expression and breast cancer cell growth, Oncol. Rep., 36, 3479, 10.3892/or.2016.5206 Liu, 2015, Hypoxia-inducible factor 1 and breast cancer metastasis, J. Zhejiang Univ.-SCIENCE B, 16, 32, 10.1631/jzus.B1400221 Malfettone, 2012, Peritumoral vascular invasion and NHERF1 expression define an immunophenotype of grade 2 invasive breast cancer associated with poor prognosis, BMC Cancer, 12, 106, 10.1186/1471-2407-12-106 Marton, 2012, Immunohistochemical expression and prognostic significance of HIF-1α and VEGF-C in neuroendocrine breast cancer, Anticancer Res., 32, 5227 Maynard, 2007, The role of hypoxia-inducible factors in cancer, Cell. Mol. Life Sci., 64, 2170, 10.1007/s00018-007-7082-2 Muz, 2015, The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy, Hypoxia, 3, 83, 10.2147/HP.S93413 Nalwoga, 2016, Strong expression of hypoxia-inducible factor-1α (HIF-1α) is associated with Axl expression and features of aggressive tumors in african breast cancer, PLoS One, 11, e0146823, 10.1371/journal.pone.0146823 Narod, 2012, Tumour size predicts long-term survival among women with lymph node-positive breast cancer, Curr. Oncol., 19, 249, 10.3747/co.19.1043 Nepal, 2012, Anti-angiogenic and anti-tumor activity of Bavachinin by targeting hypoxia-inducible factor-1α, Eur. J. Pharmacol., 691, 28, 10.1016/j.ejphar.2012.06.028 Ni, 2013, Hypoxia-induced factor-1 alpha upregulates vascular endothelial growth factor C to promote lymphangiogenesis and angiogenesis in breast cancer patients, J. Biomed. Res., 27, 478, 10.7555/JBR.27.20130021 Nie, 2018, Hypoxia-inducible factor 1-alpha expression correlates with response to neoadjuvant chemotherapy in women with breast cancer, Medicine, 97, 10.1097/MD.0000000000013551 Patel, 2016, Hypoxic tumor microenvironment: opportunities to develop targeted therapies, Biotechnol. Adv., 34, 803, 10.1016/j.biotechadv.2016.04.005 Peng, 2018, Hypoxia-inducible factor 1α regulates the transforming growth factor β1/SMAD family member 3 pathway to promote breast cancer progression, J. Breast Cancer, 21, 259, 10.4048/jbc.2018.21.e42 Petrova, 2018, The hypoxic tumour microenvironment, Oncogenesis, 7, 1, 10.1038/s41389-017-0011-9 Peurala, 2012, Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients, Breast Cancer Res. Treat., 133, 179, 10.1007/s10549-011-1750-5 Rajkovic-Molek, 2014, The prognostic importance of nuclear factor κB and hypoxia-inducible factor 1α in relation to the breast cancer subtype and the overall survival, Appl. Immunohistochem. Mol. Morphol., 22, 464, 10.1097/PAI.0b013e31829271ce Ramakrishnan, 2016, Role of intestinal HIF- 2α in health and disease, Annu. Rev. Physiol., 78, 301, 10.1146/annurev-physiol-021115-105202 Schindl, 2002, Overexpression of hypoxia-inducible factor 1α is associated with an unfavorable prognosis in lymph node-positive breast cancer, Clin. Cancer Res., 8, 1831 Schoppmann, 2006, Hypoxia inducible factor-1α correlates with VEGF-C expression and lymphangiogenesis in breast cancer, Breast Cancer Res. Treat., 99, 135, 10.1007/s10549-006-9190-3 Semenza, 2003, Targeting HIF-1 for cancer therapy, Nat. Rev. Cancer, 3, 721, 10.1038/nrc1187 Semenza, 2016, The hypoxic tumor microenvironment: a driving force for breast cancer progression, Biochimica et Biophysica Acta (BBA)-Mol. Cell Res., 1863, 382, 10.1016/j.bbamcr.2015.05.036 Shi, 2017, FBP1 expression is associated with basal-like breast carcinoma, Oncol. Lett., 13, 3046, 10.3892/ol.2017.5860 Shukla, 2019, Correlation of axillary lymph nodes involvement and Nottingham prognostic index with various histopathologic prognostic factors in invasive breast carcinoma, Int. Surg. J., 6, 1187, 10.18203/2349-2902.isj20191055 Tan, 2007, BNIP3 as a progression marker in primary human breast cancer; opposing functions in in situ versus invasive cancer, Clin. Cancer Res., 13, 467, 10.1158/1078-0432.CCR-06-1466 Tierney, 2007, Practical methods for incorporating summary time-to-event data into meta-analysis, Trials, 8, 16, 10.1186/1745-6215-8-16 Trastour, 2007, HIF‐1α and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome, Int. J. Cancer, 120, 1451, 10.1002/ijc.22436 Vaupel, 1991, Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements, Cancer Res., 51, 3316 Vaupel, 2007, Detection and characterization of tumor hypoxia using pO2 histography, Antioxid. Redox Signal., 9, 1221, 10.1089/ars.2007.1628 Vleugel, 2005, Differential prognostic impact of hypoxia induced and diffuse HIF-1α expression in invasive breast cancer, J. Clin. Pathol., 58, 172, 10.1136/jcp.2004.019885 Wang, 2014, Hypoxia-inducible factor 1α in breast cancer prognosis, Clin. Chim. Acta, 428, 32, 10.1016/j.cca.2013.10.018 Yamamoto, 2008, Hypoxia-inducible factor 1α is closely linked to an aggressive phenotype in breast cancer, Breast Cancer Res. Treat., 110, 465, 10.1007/s10549-007-9742-1 Yan, 2009, BRCA1 tumours correlate with a HIF-1 α phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression, Br. J. Cancer, 101, 1168, 10.1038/sj.bjc.6605287