The protein expression profile of ACE2 in human tissues

Molecular Systems Biology - Tập 16 Số 7 - 2020
Feria Hikmet1, Loren Méar1, Åsa Edvinsson1, Patrick Micke1, Mathias Uhlén2,3, Cecilia Lindskog1
1Rudbeck Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
2Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
3Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden

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AguiarJA TremblayBJ MansfieldMJ WoodyO LobbB BanerjeeA ChandiramohanA TiessenN Dvorkin‐GhevaA RevillSet al(2020)Gene expression andin situprotein profiling of candidate SARS‐CoV‐2 receptors in human airway epithelial cells and lung tissue.bioRxivhttps://doi.org/10.1101/2020.04.07.030742[PREPRINT]

10.1038/nbt.4096

10.3389/fgene.2019.00317

10.1093/cvr/cvaa078

Chen L, 2020, Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia, Zhonghua Jie He He Hu Xi Za Zhi, 43, 203

ChengYLR WangK ZhangM WangZ DongL LiJ YaoY GeS XuG(2020)Kidney impairment is associated with in‐hospital death of COVID‐19 patients.medRxivhttps://doi.org/10.1101/2020.02.18.20023242[PREPRINT]

ChuaRLLS TrumpS HennigBP WendischD PottF DebnathO ThürmannL KurthF KazmierskiJ TimmermannBet al(2020)Cross‐talk between the airway epithelium and activated immune cells defines severity in COVID‐19.medRxivhttps://doi.org/10.1101/2020.04.29.20084327[PREPRINT]

10.1038/s41587-020-0465-8

10.1172/jci.insight.86837

10.1038/s41467-018-06642-y

10.1056/NEJMoa2002032

10.1038/s41422-018-0099-2

10.1002/path.1570

10.1038/s41586-020-2157-4

10.1186/s13073-017-0467-4

10.1016/S0014-5793(02)03640-2

HeLMMA SunY MuhlL NaharK LiébanasEV FagerlundMJ OldnerA LiuJ GenovéG PietiläRet al(2020)Pericyte‐specific vascular expression of SARS‐CoV‐2 receptor ACE2 – implications for microvascular inflammation and hypercoagulopathy in COVID‐19 patients.bioRxivhttps://doi.org/10.1101/2020.05.11.088500[PREPRINT]

10.1016/j.cell.2020.02.052

10.1172/JCI139569

10.1016/S0140-6736(20)30183-5

HuiHZY YangX WangX HeB LiL LiH TianJ ChenY(2020a)Clinical and radiographic features of cardiac injury in patients with 2019 novel coronavirus pneumonia.medRxivhttps://doi.org/10.1101/2020.02.24.20027052[PREPRINT]

10.1016/S2213-2600(20)30193-4

10.1016/j.jinf.2020.02.026

10.1128/JVI.79.23.14614-14621.2005

Kampf C, 2012, Production of tissue microarrays, immunohistochemistry staining and digitalization within the human protein atlas, J Vis Exp, 3620

10.3390/jpm5010022

10.1038/nature13302

LeeITNT WuC‐T GoltsevY JiangS GallPA LiaoC‐K ShihL‐C SchurchCM McIlwainDR ChuPet al(2020)Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers.medRxivhttps://doi.org/10.1101/2020.05.08.20092866[PREPRINT]

10.1038/sj.emboj.7600640

10.1001/jamanetworkopen.2020.8292

10.1038/s41597-019-0351-8

10.15252/embj.2020105114

MaLXW LiD ShiL MaoY XiongY ZhangY ZhangM(2020)Effect of SARS‐CoV‐2 infection upon male gonadal function: a single center‐based study.medRxivhttps://doi.org/10.1101/2020.03.21.20037267[PREPRINT]

10.1128/JVI.01542-10

10.1038/s41587-020-0469-4

MuusCLMD EraslanG WaghrayA HeimbergG SikkemaL KobayashiY VaishnavED SubramanianA SmilieC JagadeeshKet al(2020)Integrated analyses of single‐cell atlases reveal age gender and smoking status associations with cell type‐specific expression of mediators of SARS‐CoV‐2 viral entry and highlights inflammatory programs in putative target cells.bioRxivhttps://doi.org/10.1101/2020.04.19.049254[PREPRINT]

10.1016/j.molonc.2014.03.008

10.1002/jmv.25936

RavindraNGAMM GasqueV WeiJ FillerRB HustonNC WanH Szigeti‐BuckK WangB MontgomeryRR EisenbarthSCet al(2020)Single‐cell longitudinal analysis of SARS‐CoV‐2 infection in human bronchial epithelial cells.bioRxivhttps://doi.org/10.1101/2020.05.06.081695[PREPRINT]

10.7554/eLife.27041

10.1164/rccm.201712-2410OC

10.1093/nar/gkx1029

10.1038/s41586-020-2179-y

SunKGL MaL DuanY(2020)Atlas of ACE2 gene expression in mammals reveals novel insights in transmisson of SARS‐Cov‐2.bioRxivhttps://doi.org/10.1101/2020.03.30.015644[PREPRINT]

10.1038/s41591-020-0868-6

10.1074/jbc.M002615200

10.1126/science.1260419

10.1038/nmeth.3995

10.15252/msb.20155865

10.1126/science.aax9198

10.1038/s41591-019-0468-5

10.1002/pmic.201400441

WangKCW ZhouY‐S LianJ‐Q ZhangZ DuP GongL ZhangY CuiH‐Y GengJ‐J WangBet al(2020a)SARS‐CoV‐2 invades host cells via a novel route: CD147‐spike protein.bioRxivhttps://doi.org/10.1101/2020.03.14.988345[PREPRINT]

10.1038/s41585-020-0319-7

10.1084/jem.20191130

10.1038/nature13319

10.1038/s41591-020-0817-4

10.1093/nar/gkv608

ZhaoYZZ WangY ZhouY MaY ZuoW(2020)Single‐cell RNA expression profiling of ACE2 the putative receptor of Wuhan 2019‐nCov.bioRxivhttps://doi.org/10.1101/2020.01.26.919985[PREPRINT]

10.1038/s41569-020-0360-5

10.1016/j.cell.2020.04.035

10.1007/s11684-020-0754-0