The prognostic value of 2D strain in assessment of the right ventricle in patients with dilated cardiomyopathy

European Heart Journal Cardiovascular Imaging - Tập 20 Số 9 - Trang 1043-1050 - 2019
Jong-Kwon Seo1, In Hyun Jung1, Jin Hye Park1, Gwang Sil Kim1, Hye Young Lee1, Young Sup Byun1, Byung Ok Kim1, Kun Joo Rhee1
1Department of Cardiology, Sanggye-Paik Hospital, Inje University College of Medicine, Sanggye-dong, Nowon-gu, Seoul 01757, Republic of Korea

Tóm tắt

Abstract Aims Several studies have been reported using right ventricular (RV) strain as a method for evaluating RV function in patients with various cardiovascular diseases; however, the clinical relevance of RV strain in dilated cardiomyopathy (DCM) patients with sinus rhythm is unknown. The aim of this study was to investigate the relationship between RV strain and adverse events in DCM patients with sinus rhythm. Methods and results We enrolled 143 DCM patients with sinus rhythm who had been first diagnosed, evaluated, and followed at Sanggye Paik Hospital between March 2013 and August 2017. We performed echocardiography and measured RV strain values using the apical four-chamber view. The mean age was 64.6 years. During the median follow-up period of 40.0 months, adverse cardiovascular events developed in 21 patients (14.7%). By Cox proportional hazards multivariate analysis, only RV free wall longitudinal strain (RV-FWLS) independently predicted the primary outcome. Receiver-operating characteristic curve analysis showed that the optimal RV-FWLS cut-off value to identify patients with an event was −16.5% (area under the curve = 0.703, P = 0.003). When we divided the subjects into two groups based on the RV-FWLS of −16.5%, patients with RV-FWLS <−16.5% showed more favourable clinical outcomes than that in those with RV-FWLS ≥−16.5% (log-rank test, P < 0.001). Conclusion RV-FWLS was associated with a significant prognostic impact in DCM patients with sinus rhythm.

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European Heart Journal Cardiovascular Imaging

Tập 20 Số 9

1043-1050

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