The prevalence of retinopathy in an unselected population of type 2 diabetes patients from Århus County, Denmark

Wiley - Tập 82 Số 4 - Trang 443-448 - 2004
Marianne N. Hove1, Jette Kolding Kristensen2, Torsten Lauritzen2, Toke Bek1
1Department of Ophthalmology, Århus University Hospital, Århus, Denmark
2Department of General Practice, Århus University, Århus, Denmark

Tóm tắt

Abstract.Purpose:  To determine the prevalence of diabetic retinopathy and the causes of visual impairment in an unselected population of type 2 diabetes patients, and to describe the risk factors for developing diabetic retinopathy in this population. Methods:  A total of 10 851 type 2 diabetes patients were identified in the county of Århus. A representative sample of 378 patients underwent a routine ocular examination, including fundus photography. Blood pressure and serum haemoglobin A1c, total cholesterol, high density lipoprotein cholesterol, triglyceride and apolipoprotein a were measured. Results:  The prevalence of diabetic retinopathy in the type 2 diabetes population was 31.5%. In all, 2.9% had proliferative diabetic retinopathy and 5.3% had clinically significant macular oedema. Of the latter, 8/20 (40%) were newly identified and had not yet been laser‐treated. There was a positive correlation between severity of retinopathy and duration of diabetes, HbA1c, systolic blood pressure and treatment with insulin. None of the patients had social blindness (visual acuity < 0.1), but 15/378 (4.0%) had developed visual impairment (VA < 0.3). Conclusion:  The prevalence of diabetic retinopathy and visual impairment in this unselected type 2 diabetes population was lower than anticipated from the existing literature, and causes other than diabetic retinopathy contributed significantly to the occurrence of visual loss. A substantial number of the patients with vision‐threatening diabetic maculopathy had not been referred for timely photocoagulation treatment.

Từ khóa


Tài liệu tham khảo

10.1111/j.1464-5491.1993.tb00120.x

10.1111/j.1464-5491.1989.tb01265.x

10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S

10.1038/eye.1999.43

10.1001/archopht.1996.01100140281004

10.1111/j.1600-0420.1995.tb00029.x

10.3109/02813439308994916

10.1007/s004170100324

10.1111/j.1600-0420.1996.tb00727.x

10.1111/j.1600-0420.1996.tb00729.x

Jerneld B, 1988, Prevalence of diabetic retinopathy. A population study from the Swedish island of Gotland, Acta Ophthalmol Scand (Suppl), 188, 3

10.1111/j.1755-3768.1987.tb06996.x

10.2337/diacare.21.12.2149

10.1016/S0161-6420(84)34337-8

10.1001/archopht.1984.01040030398010

10.1001/archopht.1984.01040030405011

10.1016/S0161-6420(02)01074-6

10.1001/archopht.116.3.297

Kristensen JK, 2002, Polypharmacological treatment of type 2 diabetes in daily clinical practice. A registry‐based study in the county of Aarhus, Ugeskr Laeger, 164, 5250

Kristensen JK, 2001, Use and validation of public data files for identification of the diabetic population in a Danish county, Dan Med Bull, 48, 33

10.1111/j.1755-3768.1994.tb02770.x

10.1034/j.1600-0420.1999.770522.x

10.2337/diacare.25.8.1320

10.1136/bjo.84.8.865

Morris AD, 1997, Adherence to insulin treatment, glycaemic control and ketoacidosis in insulin‐dependent diabetes mellitus. The DARTS/MEMO Collaboration. Diabetes Audit and Research in Tayside Scotland. Medicines Monitoring Unit, Lancet, 350, 1505, 10.1016/S0140-6736(97)06234-X

10.1111/j.1755-3768.1982.tb06728.x

10.1111/j.1755-3768.1984.tb08403.x

10.1002/dmrr.276

10.1007/s001250050874

10.1016/S0161-6420(01)01008-9

10.1038/eye.1993.34

10.1007/s001250051594

UK Prospective Diabetes Study Group 38, 1998, Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes, BMJ, 317, 703, 10.1136/bmj.317.7160.703

Thông tin
Thông tin xuất bản

Wiley

Tập 82 Số 4

443-448

Thông tin tác giả