The prevalence of hepatitis C virus infection in Egypt 2015: implications for future policy on prevention and treatment

Liver International - Tập 37 Số 1 - Trang 45-53 - 2017
Amr Kandeel1, Mohamad Genedy1, Samir El‐Refai1, Anna Funk2, Arnaud Fontanet3,2, Maha Talaat4,5
1Ministry of Health and Population, Cairo, Egypt
2Institut Pasteur Paris, France;
3Conservatoire National des Arts et Métiers, Paris, France
4Global Disease Detection Regional Center, US Centers for Disease Control and Prevention, Cairo, Egypt
5US Naval Medical Research Unit No. 3, Cairo, Egypt

Tóm tắt

AbstractBackground & Aims

In 2015, a national Egyptian health issue survey was conducted to describe the prevalence of hepatitis C virus (HCV) infection. In this paper, we describe the HCV burden in 2015, compare the results with the national survey conducted in 2008, and discuss the implications of the new findings on prevention of HCV in Egypt.

Methods

A multistage probability sampling approach was used, similar to the national demographic survey conducted in 2008. More than 90% of sampled individuals complied with the interview and provided blood samples.

Results

In the 15–59‐year age groups, the prevalence of HCV antibody was found to be 10.0% (95% CI 9.5–10.5) and that of HCV RNA to be 7.0% (95% CI 6.6–7.4). In children, 1–14 years old, the prevalence of HCV antibody and HCV RNA were 0.4% (95% CI 0.3–0.5) and 0.2% (95% CI 0.1–0.3) respectively. Approximately, 3.7 million persons have chronic HCV infection in the age group 15–59 in 2015. An estimated 29% reduction in HCV RNA prevalence has been seen since 2008, which is largely attributable to the ageing of the group infected 40–50 years ago during the mass schistosomiasis treatment campaigns. Prevention efforts may have also contributed to this decline, with an estimated 75% (95% CI 6–45) decrease in HCV incidence in the 0–19 year age groups over the past 20 years.

Conclusions

These findings can be used to shape future HCV prevention policies in Egypt.

Từ khóa


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Liver International

Tập 37 Số 1

45-53

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