The orphan nuclear receptor small heterodimer partner negatively regulates pancreatic beta cell survival and hyperglycemia in multiple low-dose streptozotocin-induced type 1 diabetic mice

Jung-Ran Noh1, Jung Hwan Hwang1, Yong-Hoon Kim1, Kyoung-Shim Kim1, Gil-Tae Gang1, Sang-Woo Kim1, Don-Kyu Kim2, Minho Shong3, In-Kyu Lee4, Hueng-Sik Choi2, Chul-Ho Lee1
1Laboratory Animal Center, Korea Research Institute of Bioscience and Biotechnology, University of Science and Technology, Daejeon 305-806, Republic of Korea
2National Creative Research Initiatives Center for Nuclear Receptor Signals and Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Republic of Korea
3Research Center for Endocrine and Metabolic Disease, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon 301-721, Republic of Korea
4Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721, Republic of Korea

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