The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

Nature Neuroscience - Tập 11 Số 7 - Trang 752-753 - 2008
Michael Lutter1, Ichiro Sakata2, Sherri Osborne‐Lawrence2, Sherry A. Rovinsky2, Jason Anderson2, Saendy Jung1, Shari G. Birnbaum1, Masashi Yanagisawa3, Joel K. Elmquist2, Eric J. Nestler1, Jeffrey M. Zigman2
1Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, 75390-9077, Texas, USA
2Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology and Metabolism), The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, 75390-9077, Texas, USA
3Department of Molecular Genetics and Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, 75390-9077, Texas, USA

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Tài liệu tham khảo

Lutter, M. et al. J. Neurosci. 28, 3071–3075 (2008).

Zigman, J.M. & Elmquist, J.K. Endocrinology 144, 3749–3756 (2003).

Zigman, J.M. et al. J. Clin. Invest. 115, 3564–3572 (2005).

Krishnan, V. et al. Cell 131, 391–404 (2007).

Asakawa, A. et al. Neuroendocrinology 74, 143–147 (2001).

Kristenssson, E. et al. Regul. Pept. 134, 114–117 (2006).

Abizaid, A. et al. J. Clin. Invest. 116, 3229–3239 (2006).

Diano, S. et al. Nat. Neurosci. 9, 381–388 (2006).

Lawrence, C.B., Snape, A.C., Baudoin, F.M. & Luckman, S.M. Endocrinology 143, 155–162 (2002).

Yamanaka, A. et al. Neuron 38, 701–713 (2003).

Mundinger, T.O., Cummings, D.E. & Taborsky, G.J. Jr. Endocrinology 147, 2893–2901 (2006).

Jimerson, D.C. & Wolfe, B.E. CNS Spectr. 9, 516–522 (2004).