The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15

Paula Kinsella1, Lisa M. Greene1, Sandra A. Bright1, Jade K. Pollock1, Stefania Butini2, Giuseppe Campiani2, Sebastian Bauer, David C. Williams1, Daniela M. Zisterer1
1School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland
2European Research Centre for Drug Discovery & Development, DBCF, University of Siena, Siena, Italy

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