The microRNA-15 family inhibits the TGFβ-pathway in the heart
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Swynghedauw, 1999, Molecular mechanisms of myocardial remodeling, Physiol Rev, 79, 215, 10.1152/physrev.1999.79.1.215
Villar, 2009, Gender differences of echocardiographic and gene expression patterns in human pressure overload left ventricular hypertrophy, J Mol Cell Cardiol, 46, 526, 10.1016/j.yjmcc.2008.12.024
Xia, 2009, Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload, Histochem Cell Biol, 131, 471, 10.1007/s00418-008-0541-5
Brand, 1995, The TGF beta superfamily in myocardium: ligands, receptors, transduction, and function, J Mol Cell Cardiol, 27, 5, 10.1016/S0022-2828(08)80003-X
Rosenkranz, 2004, TGF-beta1 and angiotensin networking in cardiac remodeling, Cardiovasc Res, 63, 423, 10.1016/j.cardiores.2004.04.030
Rosenkranz, 2002, Alterations of beta-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF-beta(1), Am J Physiol Heart Circ Physiol, 283, H1253, 10.1152/ajpheart.00578.2001
Brooks, 2000, Myocardial fibrosis in transforming growth factor beta(1)heterozygous mice, J Mol Cell Cardiol, 32, 187, 10.1006/jmcc.1999.1065
Kapur, 2012, Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure, Circulation, 125, 2728, 10.1161/CIRCULATIONAHA.111.080002
Rose, 2010, Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale, Physiol Rev, 90, 1507, 10.1152/physrev.00054.2009
Zhang, 2000, TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice, Nat Med, 6, 556, 10.1038/75037
Koitabashi, 2011, Pivotal role of cardiomyocyte TGF-beta signaling in the murine pathological response to sustained pressure overload, J Clin Invest, 121, 2301, 10.1172/JCI44824
Kuwahara, 2002, Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats, Circulation, 106, 130, 10.1161/01.CIR.0000020689.12472.E0
Pinto, 2000, Reduction in left ventricular messenger RNA for transforming growth factor beta(1) attenuates left ventricular fibrosis and improves survival without lowering blood pressure in the hypertensive TGR(mRen2)27 Rat, Hypertension, 36, 747, 10.1161/01.HYP.36.5.747
Hocher, 2002, Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension, J Hypertens, 20, 745, 10.1097/00004872-200204000-00034
Holmes, 2002, Results of Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial, Circulation, 106, 1243, 10.1161/01.CIR.0000028335.31300.DA
Tijsen, 2012, Non-cardiomyocyte microRNAs in heart failure, Cardiovasc Res, 93, 573, 10.1093/cvr/cvr344
Mendell, 2012, MicroRNAs in stress signaling and human disease, Cell, 148, 1172, 10.1016/j.cell.2012.02.005
Janssen, 2013, Treatment of HCV infection by targeting microRNA, N Engl J Med, 368, 1685, 10.1056/NEJMoa1209026
Hullinger, 2012, Inhibition of miR-15 protects against cardiac ischemic injury, Circ Res, 110, 71, 10.1161/CIRCRESAHA.111.244442
van Rooij, 2006, A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure, Proc Natl Acad Sci USA, 103, 18255, 10.1073/pnas.0608791103
Duisters, 2009, miR-133 and miR-30 regulate connective tissue growth factor, Circ Res, 104, 170, 10.1161/CIRCRESAHA.108.182535
van Deel, 2011, Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis, J Mol Cell Cardiol, 50, 1017, 10.1016/j.yjmcc.2011.01.016
Leenders, 2010, Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity, J Biol Chem, 285, 27449, 10.1074/jbc.M110.107292
Dennler, 1998, Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene, EMBO J, 17, 3091, 10.1093/emboj/17.11.3091
Santiago, 2010, Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro, Dev Dyn, 239, 1573, 10.1002/dvdy.22280
Divakaran, 2009, Adaptive and maladaptive effects of SMAD3 signaling in the adult heart after hemodynamic pressure overloading, Circ Heart Fail, 2, 633, 10.1161/CIRCHEARTFAILURE.108.823070
Zhang, 2012, Cross talk between cardiac myocytes and fibroblasts: from multiscale investigative approaches to mechanisms and functional consequences, Am J Physiol Heart Circ Physiol, 303, H1385, 10.1152/ajpheart.01167.2011
Porrello, 2011, MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes, Circ Res, 109, 670, 10.1161/CIRCRESAHA.111.248880
Porrello, 2013, Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family, Proc Natl Acad Sci USA, 110, 187, 10.1073/pnas.1208863110