The mediating role of catastrophizing in the relationship between pain intensity and depressed mood in older adults with persistent pain: A longitudinal analysis

Scandinavian Journal of Pain - Tập 11 - Trang 157-162 - 2016
Bradley M. Wood1, Michael K. Nicholas1, Fiona Blyth1,2, Ali Asghari1,3, Stephen Gibson4,5
1Pain Management Research Institute, University of Sydney at Royal North Shore Hospital, Sydney, Australia
2School of Public Health, University of Sydney, Sydney, Australia
3School of Psychology, Shahed University, Tehran, Iran
4National Ageing Research Institute, Royal Melbourne Hospital, VIC, Australia
5Caulfield Pain Management and Research Centre, Caulfield, VIC, Australia

Tóm tắt

Abstract Background and aims Depression is common in older adults with persistent pain. Cognitive-behavioural models of pain propose that the relationship between pain and depression is influenced or mediated by interpretations of events (cognitions), rather than by the event itself. Almost exclusively, the evidence for this position has come from studies of people aged less than 65 years. The role of cognitions in the pain experience of older adults has been unclear due to the limited and conflicting evidence available. The aim of our study was to examine the role of catastrophizing in mediating the relationship between pain intensity and depressed mood in older adults with persistent pain using reliable and valid measures for this population. Methods In a two-wave longitudinal design, a sample of 141 patients (89 women, 52 men) 65 years and over with persistent pain participating in an evaluation of a pain self-management programme completed questionnaires measuring usual level of pain intensity (NRS), depressed mood (DASS-21) and the catastrophizing factors of magnification and helplessness (PRSS) at the beginning of the programme and 6 months later. Demographic data and pain history were collected by self-completion questionnaires, which were mailed to patients prior to participating in the programme and returned by post. Results Change scores for usual level of pain intensity (NRS), depressed mood (DASS-21) and the magnification and helplessness factors on the PRSS-Catastrophizing were calculated by subtracting the scores at 6 months after completion of the study (Time 2) from the scores at the beginning of the study (Time 1). In the longitudinal analyses of mediation, using a series of regression analyses, change scores for both factors (magnification, helplessness) of the measure of catastrophizing (PRSS) totally and significantly mediated the relationship between change scores for pain intensity and depressed mood. The significant relative magnitude of beta between pain intensity and depression reduced from 0.22 to 0.13 and became non-significant after introducing magnification as a mediating variable, whilst the significant relative magnitude of beta reduced from 0.22 to 0.12 and also became non-significant after introducing helplessness as a mediating variable. Conclusions These results support a cognitive-behavioural model and highlight the importance of cognitive factors, in this case catastrophizing, in the relationship between pain intensity and depressed mood in older adults with persistent pain. Implications These findings also have important clinical implications for the treatment of older adults with persistent pain. They highlight the importance of targeting interventions to reduce the influence of catastrophizing as a prerequisite for reducing depressive symptoms in this growing population.

Tài liệu tham khảo

Antony MM, Bieling PJ, Cox BJ, Enns MW, Swinson RP. Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and a community sample. Psychol Assess 1998;10: 176–81.10.1037/1040-3590.10.2.176 Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch lntern Med 2003;163:2433–45.10.1001/archinte.163.20.2433 Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 1986;51:1173–82.10.1037/0022-3514.51.6.11733806354 Blyth FM, March LM, Brnabic AJ, Jorm LR, Williamson M, Cousins MJ. Chronic pain in Australia: a prevalence study. Pain 2001;89:127–34.1116646810.1016/S0304-3959(00)00355-9 Casten RJ, Parmelee PA, Kleban MH, Lawton MP, Katz IR. The relationships among anxiety, depression, and pain in a geriatric institutionalized sample. Pain 1995;61:271–6.10.1016/0304-3959(94)00185-H Corran TM, Farrell MJ, Helme RD, Gibson SJ. The classification of patients with chronic pain: age as a contributing factor. Clin J Pain 1997;13:207–14.930325210.1097/00002508-199709000-00005 Corran TM, Gibson SJ, Farrell MJ, Helme RD. Comparison of chronic pain experience between young and elderly patients. In: Gebhart GF, Hammond DL, Jensen TS, editors. Proceedings of the 7th world congress on pain, progress in pain research and management. Seattle: lASP Press;1994. p. 895–906. Darchuk KM, Townsend CO, Rome JD, Bruce BK, Hooten WM. Longitudinal treatment outcomes for geriatric patients with chronic non-cancer pain at an interdisciplinary pain rehabilitation program. Pain Med 2010;11:1352–64.10.1111/j.1526-4637.2010.00937.x20735746 Dominick CH, Blyth FM, Nicholas MK. Unpacking the burden: understanding the relationships between chronic pain and comorbidity in the general population. Pain 2012;153:293–304.2207131810.1016/j.pain.2011.09.018 Dotson VM, Resnick SM, Zonderman AB. Differential association of concurrent, baseline, and average depressive symptoms with cognitive decline in older adults. Am J Geriatr Psychiatry 2008;16:318–30.10.1097/JGP.0b013e3181662a9c18378557 Eriksen J, Jensen MK, Sjogren P, Ekholm O, Rasmussen NK. Epidemiology of chronic non-malignant pain in Denmark. Pain 2003;106:221–8.10.1016/S0304-3959(03)00225-214659505 Flor H, Behle DJ, Birbaumer N. Assessment of pain-related cognitions in chronic pain patients. Behav Res Ther 1993;31:63–73.10.1016/0005-7967(93)90044-U8417730 Flor H, Turk DC. Chronic back pain and rheumatoid arthritis: predicting pain and disability from cognitive variables. J Behav Med 1988;11:251–65.10.1007/BF008444312971810 Geisser ME, Robinson ME, Keefe FJ, Weiner ML. Catastrophizing, depression and the sensory, affective and evaluative aspects of chronic pain. Pain 1994;59:79–83.10.1016/0304-3959(94)90050-77854806 Gibson SJ, Helme RD. Cognitive factors and the experience of pain and suffering in older persons. Pain 2000;85:375–83.10.1016/S0304-3959(99)00284-510781910 Gloster AT, Rhoades HM, Novy D, KlotscheJ, Senior A, Kunik M, Wilson N, Stanley MA. Psychometric properties of the Depression Anxiety and Stress Scale-21 in older primary care patients. J Affect Disord 2008;110:248–59.1830464810.1016/j.jad.2008.01.023 Jensen MP, Ehde DM, Hoffman AJ, Patterson DR, Czerniecki JM, Robinson LR. Cognitions, coping and social environment predict adjustment to phantom limb pain. Pain 2002;95:133–42.1179047610.1016/S0304-3959(01)00390-6 Kee WG, Middaugh SJ, Redpath S, Hargadon R. Age as a factor in admission to chronic pain rehabilitation. Clin J Pain 1998;14:121–8.964745310.1097/00002508-199806000-00006 Keefe FJ, Brown GK, Wallston KA, Caldwell DS. Coping with rheumatoid arthritis pain: catastrophizing as a maladaptive strategy. Pain 1989;37:51–6.10.1016/0304-3959(89)90152-82726278 Keefe FJ, Lefebvre JC, Egert JR, Affleck G, Sullivan MJ, Caldwell DS. The relationship of gender to pain, pain behavior and disability in osteoarthritis patients: the role of catastrophizing. Pain 2000;87:325–34.10.1016/S0304-3959(00)00296-710963912 Lopez-Lopez A, Montorio I, Izal M, Velasco L.The role of psychological variables in explaining depression in older people with chronic pain. Aging Ment Health 2008;12:735–45.10.1080/1360786080215440819023725 Lovibond SH, Lovibond PF. Manual forthe depression anxiety stress scales. 2nd ed. Sydney: Psychology Foundation; 1995. Lunde LH, NordhuslH, Pallesen S. The effectiveness of cognitive and behavioural treatment of chronic pain in the elderly: a quantitative review. J Clin Psychol Med Settings 2009;16:254–62.1942478110.1007/s10880-009-9162-y MacKinnon DP. Introduction to statistical mediation analysis. New York, NY: Taylor & Francis Group/Lawrence Erlbaum Associates; 2008. Nicholas MK, Asghari A, Blyth FM, Wood BM, Murray R, McCabe R, Brnabic A, Beeston L, Corbett M, Sherrington C, Overton S. Self-management intervention for chronic pain in older adults: a randomised controlled trial. Pain 2013;154:824–35.10.1016/j.pain.2013.02.00923522927 Onder G, Landi F, Gambassi G, Liperoti R, Soldato M, Catananti C, Finne-Soveri H, Katona C, Carpenter l, Bernabei R. Association between pain and depression among older adults in Europe: results from the aged in home care (AdHOC) project: a cross-sectional study. J Clin Psychiatry 2005;66:982–8.1608661210.4088/JCP.v66n0804 Parmelee PA, Katz IR, Lawton MP. The relation of pain to depression among institutionalized aged. J Gerontol 1991;46:15–21.10.1093/geronj/46.1.P15 Richardson EJ, Ness TJ, Doleys DM, Banos JH, Cianfrini L, Richards JS. Depressive symptoms and pain evaluations among persons with chronic pain: catastrophizing, but not pain acceptance, shows significant effects. Pain 2009;147:147–52.1977312610.1016/j.pain.2009.08.030 Riley III JL, Wade JB, Robinson ME, Price DD. The stages of pain processing across the adult lifespan. J Pain 2000;1:162–70.10.1016/S1526-5900(00)90101-9 Roth RS, Lowery JC, Hamill JB. Assessing persistent pain and its relation to affective distress, depressive symptoms, and pain catastrophizing in patients with chronic wounds: a pilot study. Am J Phys Med Rehabil 2004;83:827–34.10.1097/01.PHM.0000140800.83146.FA15502735 Rudy TE, Kerns RD, Turk DC. Chronic pain and depression: toward a cognitivebehavioral mediation model. Pain 1988;35:129–40.10.1016/0304-3959(88)90220-5 Smeets RJ, Vlaeyen JW, Kester AD, Knottnerus JA. Reduction of pain catastrophizing mediates the outcome of both physical and cognitive-behavioral treatment in chronic low back pain. J Pain 2006;7:261–71.10.1016/j.jpain.2005.10.01116618470 Sobel ME. Asymptotic confidence intervals for indirect effects in structural equation models. In: Leinhart S, editor. Sociological methodology 1982. San Francisco: Jossey-Bass; 1982. p. 290–312. Storey JE, Rowland JT, Conforti DA, Dickson HG. The Rowland Universal Dementia Assessment Scale (RUDAS): a multicultural cognitive assessment scale. Int Psychogeriatr2004;16:13–31.10.1017/S1041610204000043 Sullivan MJ, D’Eon JL. Relation between catastrophizing and depression in chronic pain patients. J Abnorm Psychol 1990;99:260–3.214533410.1037/0021-843X.99.3.260 Sullivan MJ, Stanish W, Waite H, Sullivan M, Tripp DA. Catastrophizing, pain, and disability in patient with soft-tissue injuries. Pain 1998;77:253–60.10.1016/S0304-3959(98)00097-99808350 Sullivan MJ, Thorn B, Haythornthwaite JA, Keefe F, Martin M, Bradley LA, Lefebvre JC. Theoretical perspectives on the relation between catastrophizing and pain. Clin J Pain 2001;17:52–64.10.1097/00002508-200103000-0000811289089 Turk DC, Okifuji A, Scharff L. Chronic pain and depression: role of perceived impact and perceived control in different age cohorts. Pain 1995;61:93–101.764425310.1016/0304-3959(94)00167-D Turk DC, Rudy TE. Cognitive factors and persistent pain: a glimpse into Pandora’s box. Cognit Ther Res 1992;16:99–122.10.1007/BF01173484 Turner JA, Ersek M, Kemp C. Self-efficacy for managing pain is associated with disability, depression, and pain coping among retirement community residents with chronic pain. J Pain 2005;6:471–9.10.1016/j.jpain.2005.02.01115993826 Turner JA, Jensen MP, Romano JM. Do beliefs, coping, and catastrophizing independently predict functioning in patients with chronic pain? Pain 2000;85:115–25.1069261010.1016/S0304-3959(99)00259-6 Verhaak PF, Kerssens JJ, Dekker J, Sorbi MJ, Bensing JM. Prevalence of chronic benign pain disorder among adults: a review of the literature. Pain 1998;77:231–9.10.1016/S0304-3959(98)00117-19808348 Wideman TH, Adams H, Sullivan MJL. A prospective sequential analysis of the fear-avoidance model of pain. Pain 2009;145:45–51.10.1016/j.pain.2009.04.02219477072 Williamson GM, Schulz R. Pain, activityrestriction, and symptoms of depression among community-residing elderly adults. J Gerontol 1992;47:367–72.10.1093/geronj/47.6.P367 Wood BM, Nicholas MK, Blyth F, Asghari A, Gibson S. Assessing pain in older people with persistent pain: the NRS is valid but only provides part of the picture. J Pain 2010;11:1259–66.10.1016/j.jpain.2010.02.02520579940 Wood BM, Nicholas MK, Blyth F, Asghari A, Gibson S. The utility of the short version of the Depression Anxiety Stress Scales (DASS-21) in elderly patients with persistent pain: does age make a difference? Pain Med 2010;11:1780–90.10.1111/j.1526-4637.2010.01005.x21134119 Wood BM, Nicholas MK, Blyth F, Asghari A, Gibson S. Catastrophizing mediates the relationship between pain intensity and depressed mood in older adults with persistent pain. J Pain 2013;14:149–57.10.1016/j.jpain.2012.10.01123265846