The mechanisms of drug release from solid dispersions in water-soluble polymers

Anguiano-Igea, 1995, The properties of solid dispersions of clofibrate in polyethylene glycols, Int. J. Pharm., 70, 57

Beech, 1972, Melting of low molecular weight poly(ethylene oxide), Polymer, 13, 73, 10.1016/0032-3861(72)90138-3

Buckley, 1976, Melting behaviour of low molecular weight poly(ethylene oxide) fractions 2. Folded chain crystals, Coll. Polym. Sci., 254, 695, 10.1007/BF01643767

Chiou, 1971, Pharmaceutical applications of solid dispersions, J. Pharm. Sci., 60, 1281, 10.1002/jps.2600600902

Chiou, 1971, Phase diagram and dissolution rate studies on sulfathiazole–urea solid dispersions, J. Pharm. Sci., 60, 1333, 10.1002/jps.2600600908

Chiou, 1973, Differential thermal analysis and X-ray diffraction studies of griseofulvin–succinic acid solid dispersions, J. Pharm. Sci., 62, 498, 10.1002/jps.2600620336

Corrigan, 1985, Mechanisms of dissolution of fast release solid dispersions, Drug Dev. Ind. Pharm., 11, 697, 10.3109/03639048509056896

Corrigan, 1986, Retardation of polymeric carrier dissolution by dispersed drugs: factors influencing the dissolution of solid dispersions containing polyethylene glycols, Drug Dev. Ind. Pharm., 12, 1777, 10.3109/03639048609042609

Craig, 1990, Polyethylene glycols and drug release, Drug Dev. Ind. Pharm., 16, 2501, 10.3109/03639049009058544

Craig, 1992, The dissolution of nortriptyline HCl from polyethylene glycol solid dispersions, Int. J. Pharm., 78, 175, 10.1016/0378-5173(92)90368-C

Dubois, 1985, Similarities in the release rates of different drugs from polyethylene glycol 6000 dispersions, J. Pharm. Pharmacol., 37, 494, 10.1111/j.2042-7158.1985.tb03048.x

Ford, 1986, The current status of solid dispersions, Pharm. Acta Helv., 61, 69

Forster, 2001, Characterisation of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers., J. Pharm. Pharmacol., 53, 57, 10.1211/0022357011775532

Goyan, 1965, Dissolution rate studies III. Penetration model for describing dissolution of a multiparticulate system, J. Pharm. Sci., 54, 645, 10.1002/jps.2600540436

Higuchi, 1967, Diffusional models useful in biopharmaceutics, J. Pharm. Sci., 56, 315, 10.1002/jps.2600560302

Higuchi, 1965, Dissolution rates of polyphase mixtures, J. Pharm. Sci., 54, 1405, 10.1002/jps.2600541003

Kaur, 1979, Solid dispersions of drugs in polyoxyethyene 40 stearate: dissolution rates and physico-chemical interactions, J. Pharm. Pharmacol., 31, 48P, 10.1111/j.2042-7158.1979.tb11596.x

Lloyd, 1997, An investigation into the melting behaviour of binary mixes and solid dispersions of paracetamol and PEG 4000, J. Pharm. Sci., 86, 991, 10.1021/js970137w

Lloyd, 1997, An investigation into the production of paracetamol solid dispersions in PEG 4000 using hot stage differential interference contrast microscopy, Int. J. Pharm., 158, 39, 10.1016/S0378-5173(97)00230-5

Lloyd, 1999, A calorimetric investigation into the interaction between paracetamol and polyethylene glycol 4000 in physical mixes and solid dispersions, Eur. J. Pharm. Biopharm., 48, 59, 10.1016/S0939-6411(99)00022-3

Matsumoto, 1999, Physical properties of solid molecular dispersions of indomethacin with poly(vinylpyrrolidone) and poly(vinylpyrrolidone-co-vinylacetate) in relation to indomethacin crystallization, Pharm. Res., 16, 1722, 10.1023/A:1018906132279

Najib, 1989, Characterisation of a diflusinal polyethylene glycol solid dispersion system, Int. J. Pharm., 51, 225, 10.1016/0378-5173(89)90195-6

Said, 1974, Aust. J. Pharm. Sci., 53, 42

Sekiguchi, 1961, Studies on absorption of eutectic mixture 1. A comparison of the behaviour of eutectic mixture of sulphathiazole and that of ordinary sulfathiazole in man, Chem. Pharm. Bull., 9, 866, 10.1248/cpb.9.866

Sekiguchi, 1963, Studies on the method of thermal analysis of organic materials. III. Relations between methods of sample preparation and obtained phase diagrams, Chem. Pharm. Bull., 11, 1108, 10.1248/cpb.11.1108

Serajuddin, 1999, Solid dispersions of poorly water-soluble drugs: early promises, subsequent problems and recent breakthroughs, J. Pharm. Sci., 88, 1058, 10.1021/js980403l

Sjökvist, 1991, Physicochemical aspects of drug release V1. Drug dissolution from solid particulate dispersions and the importance of carrier and drug particle properties, Int. J. Pharm., 69, 53, 10.1016/0378-5173(91)90086-4

Sjökvist-Saers, 1992, An investigation into the mechanisms of dissolution of alkyl p-aminobenzoates from polyethylene glycol solid dispersions, Int. J. Pharm., 83, 211, 10.1016/0378-5173(82)90024-2

Sprokel, 1997, A melt-extrusion process for manufacturing matrix drug delivery systems, Int. J. Pharm., 155, 191, 10.1016/S0378-5173(97)00165-8

Tantoshaiyakul, 1996, Properties of solid dispersions of piroxicam in polyvinylpyrrolidone K-30, Int. J. Pharm., 143, 59, 10.1016/S0378-5173(96)04687-X

Ueberreiter, 1968, 219

Yalkowsky, 1972, Solubility of non-electrolytes in polar solvents, J. Pharm. Sci., 61, 983, 10.1002/jps.2600610643

Zhang, 2000, Properties of hot-melt extruded theophylline tablets containing poly(vinyl acetate), Drug Dev. Ind. Pharm., 26, 931, 10.1081/DDC-100101320