The measurement of changes in water content during hemodialysis: a non-invasive millimeter wave sensing technology
Tóm tắt
Background: Adequate hemodialysis requires not only sufficient removal of excess toxins, but also removal of water retained for the dialysis patient. There is no accurate detection technique for setting the amount of ultrafiltration during the hemodialysis. The purpose of this study was to detect changes of water in the blood during hemodialysis. Method: The changes in the permittivity of blood can be used to solve this problem very well. On the basis of the traditional metal waveguide, the stepped structure is proposed to measure the permittivity of blood. The scattering parameters of waveguide sensor is measured using vector network analyzer and the corresponding permittivity is deduced by full-wave de-embedding algorithm and transmission line method. The change in the water content of the blood during dialysis were measured for five hemodialysis volunteers. The changes of the water content in the blood were derived through changes of the permittivity. Results: The water content of each time period in the dialysis process is detected. The experiment showed that the water content gradually decreased and the water content showed a small rebound in the fourth hour. The water content of blood after dialysis is reduced by about 19–26% compared with that before dialysis. The error between the experimental and the theoretical value is less than 5.85%. Conclusions: The change of water content in the blood was obtained by measuring the permittivity of the blood during hemodialysis. The technique is proven for detecting changes in water content in the blood. The sensor structure and detection method have great clinical application value.
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