The link between long noncoding RNAs and depression

Abdul, 2009, Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling, J. Neurosci., 29, 12957, 10.1523/JNEUROSCI.1064-09.2009 Ansorge, 2007, Neurodevelopmental origins of depressive disorders, Curr. Opin. Pharmacol., 7, 8, 10.1016/j.coph.2006.11.006 Arias, 2014, DISC1-TSNAX and DAOA genes in major depression and citalopram efficacy, J. Affect. Disord., 168, 91, 10.1016/j.jad.2014.06.048 Arron, 2006, NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21, Nature, 441, 595, 10.1038/nature04678 Bahi, 2014, Selective lentiviral-mediated suppression of microRNA124a in the hippocampus evokes antidepressants-like effects in rats, Psychoneuroendocrinology, 46, 78, 10.1016/j.psyneuen.2014.04.009 Barry, 2014, The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing, Mol. Psychiatry, 19, 486, 10.1038/mp.2013.45 Bhartiya, 2012, Conceptual approaches for lncRNA drug discovery and future strategies, Expert Opin. Drug Discovery, 7, 503, 10.1517/17460441.2012.682055 Bredy, 2007, Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear, Learn. Mem., 14, 268, 10.1101/lm.500907 Butler, 2016, Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction, Epigenomics, 8, 135, 10.2217/epi.15.79 Caspi, 2003, Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene, Science, 301, 386, 10.1126/science.1083968 Centonze, 2007, The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum, J. Neurosci., 27, 8885, 10.1523/JNEUROSCI.0548-07.2007 Chaplin, 2014, Properties and use of SSRIs for depressive disorders, Prescriber, 25, 24, 10.1002/psb.1283 Chaudhury, 2015, Neuronal correlates of depression, Cell. Mol. Life Sci., 72, 4825, 10.1007/s00018-015-2044-6 Chen, 2006, Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior, Science, 314, 140, 10.1126/science.1129663 Chubb, 2008, The DISC locus in psychiatric illness, Mol. Psychiatry, 13, 36, 10.1038/sj.mp.4002106 Duman, 2016, Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants, Nat. Med., 22, 238, 10.1038/nm.4050 E., 2007, Dendritic BC200 RNA in aging and in Alzheimer's disease, Proc. Natl. Acad. Sci. U. S. A., 104 Esteller, 2011, Non-coding RNAs in human disease, Nat. Rev. Genet., 12, 861, 10.1038/nrg3074 Faghihi, 2008, Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase, Nat. Med., 14, 723, 10.1038/nm1784 Faghihi, 2010, Evidence for natural antisense transcript-mediated inhibition of microRNA function, Genome Biol., 11, R56, 10.1186/gb-2010-11-5-r56 Fatica, 2014, Long non-coding RNAs: new players in cell differentiation and development, Nat. Rev. Genet., 15, 7, 10.1038/nrg3606 Fenoglio, 2013, An emerging role for long non-coding RNA dysregulation in neurological disorders, Int. J. Mol. Sci., 14, 20427, 10.3390/ijms141020427 Galecki, 2014, COX-2 gene expression is correlated with cognitive function in recurrent depressive disorder, Psychiatry Res., 215, 488, 10.1016/j.psychres.2013.12.017 Galecki, 2015, Mechanisms underlying neurocognitive dysfunctions in recurrent major depression, Med. Sci. Monit., 21, 1535, 10.12659/MSM.893176 Gassen, 2015, FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action, Autophagy, 11, 578, 10.1080/15548627.2015.1017224 Geisler, 2013, RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts, Nat. Rev. Mol. Cell Biol., 14, 699, 10.1038/nrm3679 Gerhard, 2016, Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity, Drug Discov. Today, 10.1016/j.drudis.2016.01.016 Glanzer, 2005, RNA splicing capability of live neuronal dendrites, Proc. Natl. Acad. Sci. U. S. A., 102, 16859, 10.1073/pnas.0503783102 Guennewig, 2014, The central role of noncoding RNA in the brain, Int. Rev. Neurobiol., 116, 153, 10.1016/B978-0-12-801105-8.00007-2 Hall, 2000, Rapid and selective induction of BDNF expression in the hippocampus during contextual learning, Nat. Neurosci., 3, 533, 10.1038/75698 Hashimoto, 2015, Brain-derived neurotrophic factor (BDNF) and its precursor proBDNF as diagnostic biomarkers for major depressive disorder and bipolar disorder, Eur. Arch. Psychiatry Clin. Neurosci., 265, 10.1007/s00406-014-0557-x Hattori, 2014, DISC1 (Disrupted-in-Schizophrenia-1) regulates differentiation of oligodendrocytes, PLoS One, 9, e88506, 10.1371/journal.pone.0088506 Hetrick, 2007, Selective serotonin reuptake inhibitors (SSRIs) for depressive disorders in children and adolescents, Cochrane Database Syst. Rev., 7, 92 Hirschfeld, 2014, Differential diagnosis of bipolar disorder and major depressive disorder, J. Affect. Disord., 169, S12, 10.1016/S0165-0327(14)70004-7 Hjorthoj, 2015, Association between alcohol and substance use disorders and all-cause and cause-specific mortality in schizophrenia, bipolar disorder, and unipolar depression: a nationwide, prospective, register-based study, Lancet Psychiatry, 10.1016/S2215-0366(15)00207-2 Hodgkinson, 2004, Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder, Am. J. Hum. Genet., 75, 862, 10.1086/425586 Jernigan, 2011, The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder, Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 35, 1774, 10.1016/j.pnpbp.2011.05.010 Jia, 2015, Molecular network of neuronal autophagy in the pathophysiology and treatment of depression, Neurosci. Bull., 31, 427, 10.1007/s12264-015-1548-2 Johnson, 2012, Long non-coding RNAs in Huntington's disease neurodegeneration, Neurobiol. Dis., 46, 245, 10.1016/j.nbd.2011.12.006 Jope, 2011, Glycogen synthase kinase-3 in the etiology and treatment of mood disorders, Front. Mol. Neurosci., 4, 16, 10.3389/fnmol.2011.00016 Kadakkuzha, 2015, Transcriptome analyses of adult mouse brain reveal enrichment of lncRNAs in specific brain regions and neuronal populations, Front. Cell. Neurosci., 9, 63, 10.3389/fncel.2015.00063 Khorkova, 2015, Basic biology and therapeutic implications of lncRNA, Adv. Drug Deliv. Rev., 10.1016/j.addr.2015.05.012 Kocerha, 2015, Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease, Mol. Psychiatry, 20, 677, 10.1038/mp.2015.30 Kryger, 2012, MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics, Alcohol, 46, 629, 10.1016/j.alcohol.2012.04.002 Lee, 2010, The roles of BDNF in the pathophysiology of major depression and in antidepressant treatment, Psychiatry Investig., 7, 231, 10.4306/pi.2010.7.4.231 Lee, 2013, Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis, FEBS J., 280, 4382, 10.1111/febs.12418 Li, 2011, Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes, Mol. Cell. Biol., 31, 351, 10.1128/MCB.00259-10 Liu, 2014, Microarray profiling and co-expression network analysis of circulating lncRNAs and mRNAs associated with major depressive disorder, PLoS One, 9, e93388, 10.1371/journal.pone.0093388 Liu, 2014, Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE162AS expression, Mol. Med. Rep., 10, 1275, 10.3892/mmr.2014.2351 Lugli, 2012, Primary microRNA precursor transcripts are localized at post-synaptic densities in adult mouse forebrain, J. Neurochem., 123, 459, 10.1111/j.1471-4159.2012.07921.x Ma, 2013, On the classification of long non-coding RNAs, RNA Biol., 10, 924, 10.4161/rna.24604 Ma, 2015, LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs, Nucleic Acids Res., 43, D187, 10.1093/nar/gku1167 Marballi, 2012, Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings, PLoS One, 7, e36431, 10.1371/journal.pone.0036431 Martin, 2015, The inflammatory cytokines: molecular biomarkers for major depressive disorder?, Biomark. Med, 9, 169, 10.2217/bmm.14.29 Mckiernan, 2015, The biology of long non-coding RNA, 21 Mei, 2008, Neuregulin 1 in neural development, synaptic plasticity and schizophrenia, Nat. Rev. Neurosci., 9, 437, 10.1038/nrn2392 Menard, 2015, Pathogenesis of depression: Insights from human and rodent studies, Neuroscience Michel, 2008, Altered glial cell line-derived neurotrophic factor (GDNF) concentrations in the brain of patients with depressive disorder: a comparative post-mortem study, Eur. Psychiatry, 23, 413, 10.1016/j.eurpsy.2008.06.001 Miguel-Hidalgo, 2014, Apoptosis-related proteins and proliferation markers in the orbitofrontal cortex in major depressive disorder, J. Affect. Disord., 158, 62, 10.1016/j.jad.2014.02.010 Modarresi, 2012, Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation, Nat. Biotechnol., 30, 453, 10.1038/nbt.2158 Ng, 2012, Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors, EMBO J., 31, 522, 10.1038/emboj.2011.459 Ng, 2013, Long noncoding RNAs in development and disease of the central nervous system, Trends Genet., 29, 461, 10.1016/j.tig.2013.03.002 Nie, 2015, Melancholic depression prediction by identifying representative features in metabolic and microarray profiles with missing values, Pac. Symp. Biocomput., 455 Nutt, 2008, Relationship of neurotransmitters to the symptoms of major depressive disorder, J. Clin. Psychiatry, 69, 4 Otte, 2015, Cognitive function in older adults with major depression: effects of mineralocorticoid receptor stimulation, J. Psychiatr. Res., 69, 120, 10.1016/j.jpsychires.2015.08.001 Owczarek, 2015, Neurexin-neuroligin synaptic complex regulates schizophrenia-related DISC1/Kal-7/Rac1 “Signalosome”, Neural Plast., 2015, 10.1155/2015/167308 Papazoglou, 2014, Hippocampal GSK3β as a molecular link between obesity and depression, Mol. Neurobiol., 1 Post, 2006, Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression, Biol. Psychiatry, 59, 858, 10.1016/j.biopsych.2005.09.007 Pruunsild, 2007, Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters, Genomics, 90, 397, 10.1016/j.ygeno.2007.05.004 Puthanveettil, 2013, A strategy to capture and characterize the synaptic transcriptome, Proc. Natl. Acad. Sci. U. S. A., 110, 7464, 10.1073/pnas.1304422110 Qureshi, 2011, Non-coding RNA networks underlying cognitive disorders across the lifespan, Trends Mol. Med., 17, 337, 10.1016/j.molmed.2011.02.002 Qureshi, 2010, Long non-coding RNAs in nervous system function and disease, Brain Res., 1338, 20, 10.1016/j.brainres.2010.03.110 Rao, 2015, Genetic variants in long non-coding RNA MIAT contribute to risk of paranoid schizophrenia in a Chinese Han population, Schizophr. Res., 10.1016/j.schres.2015.04.032 Rattiner, 2004, Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning, J. Neurosci., 24, 4796, 10.1523/JNEUROSCI.5654-03.2004 Ravache, 2010, Transcriptional activation of REST by Sp1 in Huntington's disease models, PLoS One, 5, e14311, 10.1371/journal.pone.0014311 Redei, 2015, The promise of biomarkers in diagnosing major depression in primary care: the present and future, Curr. Psychiatry Rep., 17, 10.1007/s11920-015-0601-1 Ren, 2015, A co-expression network analysis reveals lncRNA abnormalities in peripheral blood in early-onset schizophrenia, Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 63, 1, 10.1016/j.pnpbp.2015.05.002 Rosenblat, 2015, The cognitive effects of antidepressants in major depressive disorder: a systematic review and meta-analysis of randomized clinical trials, Int. J. Neuropsychopharmacol. Salmena, 2011, A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?, Cell, 146, 353, 10.1016/j.cell.2011.07.014 Sen, 2008, Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications, Biol. Psychiatry, 64, 527, 10.1016/j.biopsych.2008.05.005 Sheline, 2003, Untreated depression and hippocampal volume loss, Am. J. Psychiatry, 160, 1516, 10.1176/appi.ajp.160.8.1516 Smalheiser, 2008, Natural antisense transcripts are co-expressed with sense mRNAs in synaptoneurosomes of adult mouse forebrain, Neurosci. Res., 62, 236, 10.1016/j.neures.2008.08.010 Spadaro, 2012, Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders, Front. Genet., 3, 132, 10.3389/fgene.2012.00132 Spadaro, 2015, Long noncoding RNA-directed epigenetic regulation of gene expression is associated with anxiety-like behavior in mice, Biol. Psychiatry, 10.1016/j.biopsych.2015.02.004 Sullivan, 2013, Questions about DISC1 as a genetic risk factor for schizophrenia, Mol. Psychiatry, 18, 1050, 10.1038/mp.2012.182 Talib, 2014, Disrupted-in-Schizophrenia-1(DISC1) gene as genetic markers of schizophrenia susceptibility, Asian Pac. J. Trop. Dis., 4, 236, 10.1016/S2222-1808(14)60537-5 Thomson, 2014, 708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits, Mol. Psychiatry, 19, 668, 10.1038/mp.2013.68 Velleca, 1994, A novel synapse-associated noncoding RNA, Mol. Cell. Biol., 14, 7095, 10.1128/MCB.14.11.7095 Wang, 2011, Molecular mechanisms of long noncoding RNAs, Mol. Cell, 43, 904, 10.1016/j.molcel.2011.08.018 Wang, 2008, BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus, J. Neurosci., 28, 8677, 10.1523/JNEUROSCI.2440-08.2008 Wang, 2013, Mechanisms of extracellular signal-regulated kinase/cAMP response element-binding protein/brain-derived neurotrophic factor signal transduction pathway in depressive disorder, Neural. Regen. Res., 8, 843 Wang, 2015, Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder, Transl. Psychiatry, 5, e660, 10.1038/tp.2015.144 Wilkinson, 2013, Contribution of long noncoding RNAs to autism spectrum disorder risk, Int. Rev. Neurobiol., 113, 35, 10.1016/B978-0-12-418700-9.00002-2 Willingham, 2005, A strategy for probing the function of noncoding RNAs finds a repressor of NFAT, Science, 309, 1570, 10.1126/science.1115901 Yoshida, 2012, Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder, PLoS One, 7, e42676, 10.1371/journal.pone.0042676 Zhang, 2006, Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence, Am. J. Med. Genet. B Neuropsychiatr. Genet., 141b, 387, 10.1002/ajmg.b.30332 Zheng, 2011, Evidence for association between Disrupted-in-schizophrenia 1 (DISC1) gene polymorphisms and autism in Chinese Han population: a family-based association study, Behav. Brain Funct., 7, 14, 10.1186/1744-9081-7-14 Ziats, 2013, Aberrant expression of long noncoding RNAs in autistic brain, J. Mol. Neurosci., 49, 589, 10.1007/s12031-012-9880-8