The levels of human milk microRNAs and their association with maternal weight characteristics

European Journal of Clinical Nutrition - Tập 70 Số 4 - Trang 445-449 - 2016
Yimeng Xi1, Xue Jiang1, R Li1, M Chen1, Wei Song2, X Li1
1Department of Children Health Care, Nanjing Children's Hospital, Affiliated to Nanjing Medical University, Nanjing, China.
2Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Affiliated to Nanjing University, Nanjing, China

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Gillman MW, Rifas-Shiman SL, Camargo CJ, Berkey CS, Frazier AL, Rockett HR et al. Risk of overweight among adolescents who were breastfed as infants. JAMA 2001; 285: 2461–2467.

Catli G, Olgac DN, Dundar BN . Adipokines in breast milk: an update. J Clin Res Pediatr Endocrinol 2014; 6: 192–201.

Karatas Z, Durmus AS, Dinleyici EC, Colak O, Dogruel N . Breastmilk ghrelin, leptin, and fat levels changing foremilk to hindmilk: is that important for self-control of feeding? Eur J Pediatr 2011; 170: 1273–1280.

Ambros V . The functions of animal microRNAs. Nature 2004; 431: 350–355.

Krutzfeldt J, Stoffel M . MicroRNAs: a new class of regulatory genes affecting metabolism. Cell Metab 2006; 4: 9–12.

Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008; 18: 997–1006.

Weber JA, Baxter DH, Zhang S, Huang DY, Huang KH, Lee MJ et al. The microRNA spectrum in 12 body fluids. Clin Chem 2010; 56: 1733–1741.

Kosaka N, Izumi H, Sekine K, Ochiya T . microRNA as a new immune-regulatory agent in breast milk. Silence 2010; 1: 7.

Izumi H, Kosaka N, Shimizu T, Sekine K, Ochiya T, Takase M . Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions. J Dairy Sci 2012; 95: 4831–4841.

Zhang L, Hou D, Chen X, Li D, Zhu L, Zhang Y et al. Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res 2012; 22: 107–126.

Lasser C, Alikhani VS, Ekstrom K, Eldh M, Paredes PT, Bossios A et al. Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. J Transl Med 2011; 9: 9.

Zhou Q, Li M, Wang X, Li Q, Wang T, Zhu Q et al. Immune-related microRNAs are abundant in breast milk exosomes. Int J Biol Sci 2012; 8: 118–123.

Zaragosi LE, Wdziekonski B, Brigand KL, Villageois P, Mari B, Waldmann R et al. Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol 2011; 12: R64.

Gerin I, Bommer GT, McCoin CS, Sousa KM, Krishnan V, MacDougald OA . Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis. Am J Physiol Endocrinol Metab 2010; 299: E198–E206.

Sun T, Fu M, Bookout AL, Kliewer SA, Mangelsdorf DJ . MicroRNA let-7 regulates 3T3-L1 adipogenesis. Mol Endocrinol 2009; 23: 925–931.

Ling HY, Ou HS, Feng SD, Zhang XY, Tuo QH, Chen LX et al. CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. Clin Exp Pharmacol Physiol 2009; 36: e32–e39.

Herrera BM, Lockstone HE, Taylor JM, Ria M, Barrett A, Collins S et al. Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia 2010; 53: 1099–1109.

He A, Zhu L, Gupta N, Chang Y, Fang F . Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes. Mol Endocrinol 2007; 21: 2785–2794.

Xie H, Lim B, Lodish HF . MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes 2009; 58: 1050–1057.

Martin LJ, Woo JG, Geraghty SR, Altaye M, Davidson BS, Banach W et al. Adiponectin is present in human milk and is associated with maternal factors. Am J Clin Nutr 2006; 83: 1106–1111.

Miralles O, Sanchez J, Palou A, Pico C . A physiological role of breast milk leptin in body weight control in developing infants. Obesity (Silver Spring) 2006; 14: 1371–1377.

Mehta R, Petrova A . Biologically active breast milk proteins in association with very preterm delivery and stage of lactation. J Perinatol 2011; 31: 58–62.

Ilcol YO, Hizli ZB, Ozkan T . Leptin concentration in breast milk and its relationship to duration of lactation and hormonal status. Int Breastfeed J 2006; 1: 21.

Powe CE, Knott CD, Conklin-Brittain N . Infant sex predicts breast milk energy content. Am J Hum Biol 2010; 22: 50–54.

Petherick A . Development: mother's milk: a rich opportunity. Nature 2010; 468: S5–S7.

Mandel D, Lubetzky R, Dollberg S, Barak S, Mimouni FB . Fat and energy contents of expressed human breast milk in prolonged lactation. Pediatrics 2005; 116: e432–e435.

Dallas DC, Smink CJ, Robinson RC, Tian T, Guerrero A, Parker EA et al. Endogenous human milk peptide release is greater after preterm birth than term birth. J Nutr 2015; 145: 425–433.

Baier SR, Nguyen C, Xie F, Wood JR, Zempleni J . MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood mononuclear cells, HEK-293 kidney cell cultures, and mouse livers. J Nutr 2014; 144: 1495–1500.

Petersen PS, Lei X, Seldin MM, Rodriguez S, Byerly MS, Wolfe A et al. Dynamic and extensive metabolic state-dependent regulation of cytokine expression and circulating levels. Am J Physiol Regul Integr Comp Physiol 2014; 307: R1458–R1470.

Ambeba EJ, Styn MA, Kuller LH, Brooks MM, Evans RW, Burke LE . Longitudinal effects of weight loss and regain on cytokine concentration of obese adults. Metabolism 2013; 62: 1218–1222.

Andreas NJ, Hyde MJ, Gale C, Parkinson JR, Jeffries S, Holmes E et al. Effect of maternal body mass index on hormones in breast milk: a systematic review. PLoS One 2014; 9: e115043.

Yan X, Huang Y, Zhao JX, Rogers CJ, Zhu MJ, Ford SP et al. Maternal obesity downregulates microRNA let-7 g expression, a possible mechanism for enhanced adipogenesis during ovine fetal skeletal muscle development. Int J Obes (Lond) 2013; 37: 568–575.

Noureldeen AF, Qusti SY, Al-Seeni MN, Bagais MH . Maternal leptin, adiponectin, resistin, visfatin and tumor necrosis factor-alpha in normal and gestational diabetes. Indian J Clin Biochem 2014; 29: 462–470.

Zhao C, Dong J, Jiang T, Shi Z, Yu B, Zhu Y et al. Early second-trimester serum miRNA profiling predicts gestational diabetes mellitus. PLoS One 2011; 6: e23925.

Ley SH, Hanley AJ, Sermer M, Zinman B, O'Connor DL . Associations of prenatal metabolic abnormalities with insulin and adiponectin concentrations in human milk. Am J Clin Nutr 2012; 95: 867–874.