The in vitro immunomodulatory effect of multi-walled carbon nanotubes by multilayer analysis

NanoImpact - Tập 31 - Trang 100476 - 2023
Veera Hautanen1,2, Jack Morikka1, Laura Aliisa Saarimäki1, Jan Bisenberger1, Tarja Toimela1, Angela Serra1,3, Dario Greco1,2,4
1Finnish Hub for Development and Validation of Integrated Approaches (FHAIVE), Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, Tampere 33520, Finland
2Institute of Biotechnology, University of Helsinki, P.O.Box 56, Helsinki, Uusimaa 00014, Finland
3Tampere Institute for Advanced Study, Tampere University, Kalevantie 4, Tampere 33100, Finland
4Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Finland

Tài liệu tham khảo

Adler, 2020, Principles of cell circuits for tissue repair and fibrosis, iScience., 23, 100841, 10.1016/j.isci.2020.100841 Banchereau, 2012, From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines, Nat. Immunol., 13, 925, 10.1038/ni.2406 Beg, 2011, Advancement in carbon nanotubes: basics, biomedical applications and toxicity, J. Pharm. Pharmacol., 63, 141, 10.1111/j.2042-7158.2010.01167.x Bihari, 2008, Optimized dispersion of nanoparticles for biological in vitro and in vivo studies, Part. Fibre. Toxicol., 5, 14, 10.1186/1743-8977-5-14 Bosshart, 2016, THP-1 cells as a model for human monocytes, Ann. Transl. Med., 4, 438, 10.21037/atm.2016.08.53 Bou Zerdan, 2021, Mechanisms of immunotoxicity: stressors and evaluators, Int. J. Mol. Sci., 22, 10.3390/ijms22158242 Braicu, 2019, A comprehensive review on MAPK: a promising therapeutic target in cancer, Cancers (Basel)., 11, 10.3390/cancers11101618 CDC, 2013 Chanput, 2014, THP-1 cell line: an in vitro cell model for immune modulation approach, Int. Immunopharmacol., 23, 37, 10.1016/j.intimp.2014.08.002 Chen, 2014, Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway, Toxicol. Lett., 226, 150, 10.1016/j.toxlet.2014.02.004 Cheng, 2021, Nanomaterials for cancer therapy: current progress and perspectives, J. Hematol. Oncol., 14, 85, 10.1186/s13045-021-01096-0 David, 2016, Determining the relationship between nanoparticle characteristics and immunotoxicity: key challenges and approaches, Nanomedicine (London), 11, 1447, 10.2217/nnm-2016-0017 De Volder, 2013, Carbon nanotubes: present and future commercial applications, Science., 339, 535, 10.1126/science.1222453 Dietert, 2007, Methodologies for developmental immunotoxicity (DIT) testing, Methods., 41, 123, 10.1016/j.ymeth.2006.06.018 Donaldson, 2010, Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma, Part. Fibre. Toxicol., 7, 5, 10.1186/1743-8977-7-5 Dong, 2018, Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis, Nanotoxicology., 12, 153, 10.1080/17435390.2018.1425501 Dong, 2018, Type 2 immune mechanisms in carbon nanotube-induced lung fibrosis, Front. Immunol., 9, 1120, 10.3389/fimmu.2018.01120 Dong, 2015, Transactivator of transcription (TAT) peptide- chitosan functionalized multiwalled carbon nanotubes as a potential drug delivery vehicle for cancer therapy, Int. J. Nanomedicine, 10, 3829 Dong, 2015, Pathologic and molecular profiling of rapid-onset fibrosis and inflammation induced by multi-walled carbon nanotubes, Arch. Toxicol., 89, 621, 10.1007/s00204-014-1428-y Dusinska, 2017, Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: new strategies for toxicity testing?, Food Chem. Toxicol., 109, 797, 10.1016/j.fct.2017.08.030 Elsabahy, 2013, Cytokines as biomarkers of nanoparticle immunotoxicity, Chem. Soc. Rev., 42, 5552, 10.1039/c3cs60064e Fiers, 1999, More than one way to die: apoptosis, necrosis and reactive oxygen damage, Oncogene., 18, 7719, 10.1038/sj.onc.1203249 Foroozandeh, 2018, Insight into cellular uptake and intracellular trafficking of nanoparticles, Nanoscale Res. Lett., 13, 339, 10.1186/s11671-018-2728-6 Fraser, 2020, Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities, Part. Fibre. Toxicol., 17, 62, 10.1186/s12989-020-00392-w Fukushima, 2018, Carcinogenicity of multi-walled carbon nanotubes: challenging issue on hazard assessment, J. Occup. Health, 60, 10, 10.1539/joh.17-0102-RA Gangwal, 2011, Informing selection of nanomaterial concentrations for ToxCast in vitro testing based on occupational exposure potential, Environ. Health Perspect., 119, 1539, 10.1289/ehp.1103750 Gao, 2015, Toxicity mechanisms identification via gene set enrichment analysis of time-series toxicogenomics data: impact of time and concentration, Environ. Sci. Technol., 49, 4618, 10.1021/es505199f Gou, 2010, Mechanistic toxicity assessment of nanomaterials by whole-cell-array stress genes expression analysis, Environ. Sci. Technol., 44, 5964, 10.1021/es100679f Halappanavar, 2020, Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale, Part. Fibre. Toxicol., 17, 16, 10.1186/s12989-020-00344-4 Hamilton, 2013, Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology, Part. Fibre. Toxicol., 10, 57, 10.1186/1743-8977-10-57 Hockley, 2006, Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2, BMC Genomics, 7, 260, 10.1186/1471-2164-7-260 Horstmann, 2021, Transcriptome profile alterations with carbon nanotubes, quantum dots, and silver nanoparticles: a review, Genes (Basel), 12, 10.3390/genes12060794 Joris, 2013, Assessing nanoparticle toxicity in cell-based assays: influence of cell culture parameters and optimized models for bridging the in vitro-in vivo gap, Chem. Soc. Rev., 42, 8339, 10.1039/c3cs60145e Joseph, 2017, Transcriptomics in toxicology, Food Chem. Toxicol., 109, 650, 10.1016/j.fct.2017.07.031 Kim, 2019, The role of nanovaccine in cross-presentation of antigen-presenting cells for the activation of CD8+ T cell responses, Pharmaceutics., 11, 10.3390/pharmaceutics11110612 Kinaret, 2017, Inhalation and oropharyngeal aspiration exposure to rod-like carbon nanotubes induce similar airway inflammation and biological responses in mouse lungs, ACS Nano, 11, 291, 10.1021/acsnano.6b05652 Kinaret, 2020, Carbon nanomaterials promote M1/M2 macrophage activation, Small., 16, 10.1002/smll.201907609 Klumpp, 2006, Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics, Biochim. Biophys. Acta, 1758, 404, 10.1016/j.bbamem.2005.10.008 Kobayashi, 2017, Review of toxicity studies of carbon nanotubes, J. Occup. Health, 59, 394, 10.1539/joh.17-0089-RA Lacy, 2006, Mechanisms of degranulation in neutrophils, Allergy, Asthma Clin. Immunol., 2, 98, 10.1186/1710-1492-2-3-98 Leek, 2012, The sva package for removing batch effects and other unwanted variation in high-throughput experiments, Bioinformatics., 28, 882, 10.1093/bioinformatics/bts034 Liu, 2017, Effects of engineered nanoparticles on the innate immune system, Semin. Immunol., 34, 25, 10.1016/j.smim.2017.09.011 Loret, 2022, Innate but not adaptive immunity regulates lung recovery from chronic exposure to graphene oxide nanosheets, Adv. Sci. (Weinh)., 9 Manzanares, 2020, Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell, Pharmaceutics., 12, 10.3390/pharmaceutics12040371 Marwah, 2019, eUTOPIA: solUTion for omics data PreprocessIng and analysis, Source Code Biol. Med., 14, 1, 10.1186/s13029-019-0071-7 Meng, 2015, Carbon nanotubes activate macrophages into a M1/M2 mixed status: recruiting naïve macrophages and supporting angiogenesis, ACS Appl. Mater. Interfaces, 7, 3180, 10.1021/am507649n Mercer, 2013, Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes, Part. Fibre. Toxicol., 10, 33, 10.1186/1743-8977-10-33 Misharin, 2017, Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span, J. Exp. Med., 214, 2387, 10.1084/jem.20162152 Moore, 2001, Protection from pulmonary fibrosis in the absence of CCR2 signaling, J. Immunol., 167, 4368, 10.4049/jimmunol.167.8.4368 Mukherjee, 2018, Macrophage sensing of single-walled carbon nanotubes via toll-like receptors, Sci. Rep., 8, 1115, 10.1038/s41598-018-19521-9 Murphy, 2012, The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells, Part. Fibre. Toxicol., 9, 8, 10.1186/1743-8977-9-8 Murray, 2014, Cytokine secretion in macrophages: snares, rabs, and membrane trafficking, Front. Immunol., 5, 538, 10.3389/fimmu.2014.00538 Nagai, 2011, Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis, Proc. Natl. Acad. Sci. U. S. A., 108, E1330, 10.1073/pnas.1110013108 Oberdörster, 2015, Inhalation exposure to carbon nanotubes (CNT) and carbon nanofibers (CNF): methodology and dosimetry, J. Toxicol. Environ. Health B Crit. Rev., 18, 121, 10.1080/10937404.2015.1051611 Ogawa, 2021, Macrophages in lung fibrosis, Int. Immunol., 33, 665, 10.1093/intimm/dxab040 Ott, 2007, Tumor necrosis factor-alpha- and interleukin-1-induced cellular responses: coupling proteomic and genomic information, J. Proteome Res., 6, 2176, 10.1021/pr060665l Poulsen, 2016, Multi-walled carbon nanotube physicochemical properties predict pulmonary inflammation and genotoxicity, Nanotoxicology., 10, 1263, 10.1080/17435390.2016.1202351 Prame Kumar, 2018, Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease, Cell Tissue Res., 371, 551, 10.1007/s00441-017-2753-2 Rasmussen, 2014 Ritchie, 2015, Limma powers differential expression analyses for RNA-sequencing and microarray studies, Nucleic Acids Res., 43, 10.1093/nar/gkv007 Rydman, 2014, Inhalation of rod-like carbon nanotubes causes unconventional allergic airway inflammation, Part. Fibre. Toxicol., 11, 48, 10.1186/s12989-014-0048-2 Sargent, 2014, Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes, Part. Fibre. Toxicol., 11, 3, 10.1186/1743-8977-11-3 Scala, 2018, Multi-omics analysis of ten carbon nanomaterials effects highlights cell type specific patterns of molecular regulation and adaptation, NanoImpact., 11, 99, 10.1016/j.impact.2018.05.003 Scala, 2019, FunMappOne: a tool to hierarchically organize and visually navigate functional gene annotations in multiple experiments, BMC Bioinform., 20, 79, 10.1186/s12859-019-2639-2 Scala, 2021, Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice, Carbon N Y., 178, 563, 10.1016/j.carbon.2021.03.045 Septiadi, 2019, Quantification of carbon nanotube doses in adherent cell culture assays using UV-VIS-NIR spectroscopy, Nanomaterials (Basel)., 9, 10.3390/nano9121765 Serra, 2020, BMDx: a graphical shiny application to perform benchmark dose analysis for transcriptomics data, Bioinformatics., 36, 2932, 10.1093/bioinformatics/btaa030 Sharma, 2016, Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs), Arch. Toxicol., 90, 1605, 10.1007/s00204-016-1742-7 Smith, 2014, From immunotoxicity to nanotherapy: the effects of nanomaterials on the immune system, Toxicol. Sci., 138, 249, 10.1093/toxsci/kfu005 Soares-Silva, 2016, The mitogen-activated protein kinase (MAPK) pathway: role in immune evasion by trypanosomatids, Front. Microbiol., 183 Sohaebuddin, 2010, Nanomaterial cytotoxicity is composition, size, and cell type dependent, Part. Fibre. Toxicol., 7, 22, 10.1186/1743-8977-7-22 Stella, 2022, The oncogenic landscape of the idiopathic pulmonary fibrosis: a narrative review, Transl. Lung Cancer Res., 11, 472, 10.21037/tlcr-21-880 Tsuchiya, 1980, Establishment and characterization of a human acute monocytic leukemia cell line (THP-1), Int. J. Cancer, 26, 171, 10.1002/ijc.2910260208 Umeda, 2013, Two-week toxicity of multi-walled carbon nanotubes by whole-body inhalation exposure in rats, J. Toxicol. Pathol., 26, 131, 10.1293/tox.26.131 Vippola, 2009 Wendisch, 2021, SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis, Cell., 184, 6243, 10.1016/j.cell.2021.11.033 Wynn, 2008, Cellular and molecular mechanisms of fibrosis, J. Pathol., 214, 199, 10.1002/path.2277 Yang, 2007, BMDExpress: a software tool for the benchmark dose analyses of genomic data, BMC Genomics, 387, 10.1186/1471-2164-8-387 Yang, 2021, FGF/FGFR signaling: from lung development to respiratory diseases, Cytokine Growth Factor Rev., 62, 94, 10.1016/j.cytogfr.2021.09.002 Zhang, 2007, Cytokines, inflammation, and pain, Int. Anesthesiol. Clin., 45, 27, 10.1097/AIA.0b013e318034194e