The hypothalamic–pituitary–adrenal axis in asthmatic children

Trends in Endocrinology & Metabolism - Tập 19 - Trang 32-38 - 2008
Kostas N. Priftis1, Anastasios Papadimitriou2, Polyxeni Nicolaidou2, George P. Chrousos3
1Department of Allergy-Pneumonology, Penteli Children's Hospital, Athens, Greece
2Third Department of Pediatrics, Attikon University Hospital, Athens University Medical School, Athens, Greece
3First Department of Pediatrics, Aghia Sophia Children's Hospital, Athens University Medical School, Athens, Greece

Tài liệu tham khảo

Skoner, 2002, Balancing safety and efficacy in pediatric asthma management, Pediatrics, 109, 381, 10.1542/peds.109.SE1.381 Allen, 2003, Inhaled corticosteroids past lessons and future issues, J. Allergy Clin. Immunol., 112, S1, 10.1016/S0091-6749(03)01859-1 Goldstein, 1983, Effect of inhaled beclomethasone dipropionate on hypothalamic-pituitary-adrenal axis function in children with asthma, Pediatrics, 72, 60, 10.1542/peds.72.1.60 Katsunuma, 1992, Adrenal function of children with bronchial asthma treated with beclomethasone dipropionate, Ann. Allergy, 69, 529 Nicolaizik, 1994, Endocrine and lung function in asthmatic children on inhaled corticosteroids, Am. J. Respir. Crit. Care Med., 150, 624, 10.1164/ajrccm.150.3.8087329 Kannisto, 2000, Adrenal suppression, evaluated by a low-dose ACTH-test, and growth in asthmatic children treated with inhaled steroids, J. Clin. Endocrinol. Metab., 85, 652, 10.1210/jc.85.2.652 Hollman, 1988, Overt glucocorticoid excess due to inhaled corticosteroid therapy, Pediatrics, 81, 452, 10.1542/peds.81.3.452 Priftis, 1991, Unexpected side effects of inhaled steroids, Eur. J. Pediatr., 150, 448, 10.1007/BF02093730 Wong, 2002, Growth and adrenal suppression in asthmatic children on moderate to high doses of fluticasone propionate, J. Paediatr. Child Health, 38, 59, 10.1046/j.1440-1754.2002.00717.x Buske-Kirschbaum, 1997, Attenuated free cortisol response to psychosocial stress in children with atopic dermatitis, Psychosom. Med., 59, 419, 10.1097/00006842-199707000-00012 Wamboldt, 2003, Adolescents with atopic disorders have an attenuated cortisol response to laboratory stress, J. Allergy Clin. Immunol., 111, 509, 10.1067/mai.2003.140 Richards, 2005, Response of the hypothalamic-pituitary-adrenal axis to psychological stress in patients with psoriasis, Br. J. Dermatol., 153, 1114, 10.1111/j.1365-2133.2005.06817.x Volovitz, 1993, Growth and pituitary-adrenal function in children with severe asthma treated with inhaled budesonide, N. Engl. J. Med., 329, 1703, 10.1056/NEJM199312023292305 Priftis, 2006, Adrenal function improves in asthmatic children on inhaled steroids: a longitudinal study, Neuroimmunomodulation, 13, 56, 10.1159/000094645 Chrousos, 2000, Stress, chronic inflammation, and emotional and physical well-being: concurrent effects and chronic sequelae, J. Allergy Clin. Immunol., 106, S275, 10.1067/mai.2000.110163 Elenkov, 2000, Stress hormones, Th1/Th2 patterns, pro/anti-inflammatory cytokines and susceptibility to disease, Trends Endocrinol. Metab., 10, 359, 10.1016/S1043-2760(99)00188-5 Johansson, 2001, A revised nomenclature for allergy. 2001 An EAACI position statement from the EAACI nomenclature task force, Allergy, 56, 813, 10.1034/j.1398-9995.2001.t01-1-00001.x Nakajima, 2007, Role of cytokines in allergic airway inflammation, Int. Arch. Allergy Immunol., 142, 265, 10.1159/000097357 Calcagni, 2006, Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases, Ann. N. Y. Acad. Sci., 1069, 62, 10.1196/annals.1351.006 Renauld, 2001, New insights into the role of cytokines in asthma, J. Clin. Pathol., 54, 577, 10.1136/jcp.54.8.577 Keatings, 1997, Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum, J. Allergy Clin. Immunol., 99, 693, 10.1016/S0091-6749(97)70032-0 Munthe-Kaas, 2007, HLA Dr-Dq haplotypes and the TNFA-308 polymorphism: associations with asthma and allergy, Allergy, 62, 991, 10.1111/j.1398-9995.2007.01377.x Doganci, 2005, Pathological role of IL-6 in the experimental allergic bronchial asthma in mice, Clin. Rev. Allergy Immunol., 28, 257, 10.1385/CRIAI:28:3:257 Silverman, 2004, Corticotropin-releasing hormone deficiency increases allergen-induced airway inflammation in a mouse model of asthma, J. Allergy Clin. Immunol., 114, 747, 10.1016/j.jaci.2004.06.055 Mastorakos, 1993, Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans, J. Clin. Endocrinol. Metab., 77, 1690, 10.1210/jc.77.6.1690 Jaattela, 1991, Tumor necrosis factor as a potent inhibitor of adrenocorticotropin-induced cortisol production and steroidogenic P450 enzyme gene expression in cultured human fetal adrenal cells, Endocrinology, 128, 623, 10.1210/endo-128-1-623 Reincke, 1994, Impairment of adrenocortical function associated with increased plasma tumor necrosis factor-alpha and interleukin-6 concentrations in African trypanosomiasis, Neuroimmunomodulation, 1, 14, 10.1159/000095930 Harbuz, 1992, Action of interleukin-2 and interleukin-4 on CRF mRNA in the hypothalamus and POMC mRNA in the anterior pituitary, Brain Behav. Immun., 6, 214, 10.1016/0889-1591(92)90044-O Joachim, 2003, Stress enhances airway reactivity and airway inflammation in an animal model of allergic bronchial asthma, Psychosom. Med., 65, 811, 10.1097/01.PSY.0000088582.50468.A3 Joachim, 2006, Upregulation of tumor necrosis factor-alpha by stress and substance p in a murine model of allergic airway inflammation, Neuroimmunomodulation, 13, 43, 10.1159/000094394 Sandberg, 2004, Asthma exacerbations in children immediately following stressful life events: a Cox's hierarchical regression, Thorax, 59, 1046, 10.1136/thx.2004.024604 Buske-Kirschbaum, 2002, Altered responsiveness of the hypothalamus-pituitary-adrenal axis and the sympathetic adrenomedullary system to stress in patients with atopic dermatitis, J. Clin. Endocrinol. Metab., 87, 4245, 10.1210/jc.2001-010872 Buske-Kirschbaum, 2003, Blunted cortisol responses to psychosocial stress in asthmatic children: a general feature of atopic disease?, Psychosom. Med., 65, 806, 10.1097/01.PSY.0000095916.25975.4F Barr, 2002, The relation between adrenal function and the severity of bronchial hyperresponsiveness in children as measured by the methacholine provocation test, J. Pediatr. Endocrinol. Metab., 19, 307, 10.1515/JPEM.2002.15.3.307 Ball, 2006, Cortisol circadian rhythms and stress responses in infants at risk of allergic disease, J. Allergy Clin. Immunol., 117, 306, 10.1016/j.jaci.2005.11.009 Chrousos, 2007, Basal and cosyntropin-stimulated plasma cortisol concentrations, as measured by high-performance liquid chromatography, in children aged 5 months to <6 years, J. Clin. Endocrinol. Metab., 92, 2125, 10.1210/jc.2006-1554 Ozbek, 2006, Evaluation of hypothalamic-pituitary-adrenal axis (HPA) suppression by low-dose (0.5μg) and standard-dose (250μg) adrenocorticotropic hormone (ACTH) tests in asthmatic children treated with inhaled corticosteroid, J. Pediatr. Endocrinol. Metab., 19, 1015, 10.1515/JPEM.2006.19.8.1015 Bacharier, 2004, Long-term effect of budesonide on hypothalamic-pituitary-adrenal axis function in children with mild to moderate asthma, Pediatrics, 113, 1693, 10.1542/peds.113.6.1693 Zollner, 2007, Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled corticosteroids: part 1. Which test should be used?, Pediatr. Allergy Immunol., 18, 401, 10.1111/j.1399-3038.2007.00540.x Bernstein, 2007, Evaluation of tests of hypothalamic-pituitary-adrenal axis function used to measure effects of inhaled corticosteroids, Ann. Allergy Asthma Immunol., 98, 118, 10.1016/S1081-1206(10)60683-7 Zollner, 2007, Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled corticosteroids (Part 2) – the risk as determined by gold standard adrenal function tests: a systematic review. Which test should be used?, Pediatr. Allergy Immunol., 18, 469, 10.1111/j.1399-3038.2007.00539.x Hindmarsh, 2002, Commentary: exogenous glucocorticoids influence adrenal function, but assessment can be difficult, BMJ, 324, 1083 Marcus-Perlman, 2006, Low-dose ACTH (1 microg) salivary test: a potential alternative to the classical blood test, Clin. Endocrinol. (Oxf.), 64, 215, 10.1111/j.1365-2265.2006.02451.x Silva, 2007, Salivary cortisol to assess the hypothalamic-pituitary-adrenal axis in healthy children under 3 years old, J. Pediatr. (Rio J.), 83, 121, 10.1590/S0021-75572007000200005 Global Strategy for Asthma Management and Prevention 2006. http://www.who.int/respiratory/asthma/GINA_WR_2006_copyright%5b1%5d.pdf Priftis, 2006, The effect of inhaled budesonide on adrenal and growth suppression in asthmatic children, Eur. Respir. J., 27, 316, 10.1183/09031936.06.00071905 Dunlop, 2004, Monitoring growth in asthmatic children treated with high dose inhaled glucocorticoids does not predict adrenal suppression, Arch. Dis. Child., 89, 713, 10.1136/adc.2002.022533 Paton, 2006, Adrenal responses to low dose synthetic ACTH (Synacthen) in children receiving high dose inhaled fluticasone, Arch. Dis. Child., 91, 808, 10.1136/adc.2005.087247 Todd, 2002, Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom, Arch. Dis. Child., 87, 457, 10.1136/adc.87.6.457 Pedersen, 2006, Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials, Drug Saf., 29, 599, 10.2165/00002018-200629070-00005 Dautzenberg, 2002, The CRF peptide family and their receptors: yet more partners discovered, Trends Pharmacol. Sci., 23, 71, 10.1016/S0165-6147(02)01946-6 Kyrou, 2006, Stress, visceral obesity, and metabolic complications, Ann. N. Y. Acad. Sci., 1083, 77, 10.1196/annals.1367.008 Gantz, 2003, The melanocortin system, Am. J. Physiol. Endocrinol. Metab., 284, E468, 10.1152/ajpendo.00434.2002 Bamberger, 1995, Glucocorticoid receptor β, a potential endogenous inhibitor of glucocorticoid action in humans, J. Clin. Invest., 95, 2431, 10.1172/JCI117943 Oakley, 1999, The dominant negative activity of the human glucocorticoid receptor β isoform. Specificity and mechanisms of action, J. Biol. Chem., 274, 27857, 10.1074/jbc.274.39.27857 Chrousos, 2007, Glucocorticoid action networks and complex psychiatric and/or somatic disorders, Stress, 10, 213, 10.1080/10253890701292119 Tantisira, 2004, Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids, Hum. Mol. Genet., 13, 1353, 10.1093/hmg/ddh149 Slawik, 2004, Characterization of an adrenocorticotropin (ACTH) receptor promoter polymorphism leading to decreased adrenal responsiveness to ACTH, J. Clin. Endocrinol. Metab., 89, 3131, 10.1210/jc.2003-032010 Huizenga, 1998, A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo, J. Clin. Endocrinol. Metab., 83, 144, 10.1210/jc.83.1.144 Van Rossum, 2002, A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels, Diabetes, 51, 3128, 10.2337/diabetes.51.10.3128 Stevens, 2004, Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype, J. Clin. Endocrinol. Metab., 89, 892, 10.1210/jc.2003-031235 Watt, 1992, Abnormalities of glucocorticoid metabolism and the renin-angiotensin system: a four-corners approach to the identification of genetic determinants of blood pressure, J. Hypertens., 10, 473, 10.1097/00004872-199205000-00011 Buemann, 1997, Abdominal visceral fat is associated with a BclI restriction fragment length polymorphism at the glucocorticoid receptor gene locus, Obes. Res., 5, 186, 10.1002/j.1550-8528.1997.tb00292.x Ukkola, 2001, Glucocorticoid receptor Bcl I variant is associated with an increased atherogenic profile in response to long-term overfeeding, Atherosclerosis, 157, 221, 10.1016/S0021-9150(00)00712-7