The genetic toxicology of hydroxylamines

Mutation Research/Reviews in Genetic Toxicology - Tập 86 - Trang 155-191 - 1981
Peter Marfey1, Eleanor Robinson1
1Department of Biological Sciences, State University of New York at Albany, Albany, NY 12222, U.S.A.

Tài liệu tham khảo

Abbondandolo, 1978, Evaluation of a short-term test for the detection of genetic damage in human cultured cells, Mutation Res., 53, 141, 10.1016/0165-1161(78)90147-4 Abdelal, 1978, Arginine auxotrophic phenotype of mutations in pyra of Salmonella typhimurium; Role of N-acetylornithine in the maturation of mutant carbamylphosphate synthetase, J. Bacteriol., 134, 528, 10.1128/JB.134.2.528-536.1978 Airapetyan, 1976, Protective effect of superoptimal temperatures in the treatment of seeds with mutagens, Biol. Zh. Arm., 29, 84 Alikhanyan, 1975, Comparative study of mutagenesis in amber mutants of bacteriophage T4, Sov. Genet., 10, 241 Alikhanyan, 1969, Gene-specific effect of hydroxylamine in the induction of amber mutations in bacteriophage T4B, Sov. Genet., 5, 666 Alikhanian, 1969, Gene-specific effect of hydroxylamine in induction of amber mutations in bacteriophage T4B, Mutation Res., 8, 451, 10.1016/0027-5107(69)90062-1 Alikhanyan, 1966, Use of TS-mutations in T4B phage in a study of the genetic control of DNA synthesis, Sov. Genet., 2, 9 Alikhanian, 1973, Reverse mutations of two pairs of amber-opal mutations in gene 47 of bacteriophage T4B, Genetics, 74, S4 Alikhanyan, 1972, Study of opal mutations in bacteriophage T4B, 1. Localization of amber and opal mutations on the map of 47 in phage T4B, Sov. Genet., 8, 223 Alikhanian, 1969, The fine structure of the gene controlling the synthesis of DNA polymerase in bacteriophage T4B, Genetics, 61, 773, 10.1093/genetics/61.4.773 Alikhanyan, 1970, Comparative genetic investigation of R mutants of T2L and T4B phages, 2. Comparison of the fine genetic structure of the RII regions of T2L and T4B phages, Sov. Genet., 6, 1238 Arlett, 1970, The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation, Int. J. Radiation Biol., 17, 515, 10.1080/09553007014550651 Ashri, 1974, Sensitivity of developmental stages of peanut (A. hypogaea) embryos and ovaries to several chemical mutagen treatments, Radiation Botany, 14, 223, 10.1016/S0033-7560(74)80011-6 Augustine, 1975, Influence of pH on mutagenic specificity and efficiency of hydroxylamine, hydrazine and ethyl methanesulfonate in two rice types, Radiation Botany, 15, 267, 10.1016/S0033-7560(75)80026-3 Balandina, 1977, Isolation and study of int. mutants of bacteriophage PH181, Sov. Genet., 13, 747 Baltz, 1972, Bacteriophage T4 transformation; An assay for mutations induced in vitro, Virology, 49, 462, 10.1016/0042-6822(72)90498-9 Banks, 1970, Hydroxylamine mutagenesis; An in vitro and in vivo study, Heredity, 25, 686 Baumberg, 1976, Isolation of amber mutant of a P group R factor after hydroxylamine mutagenesis of a transducing lystate, J. Gen. Microbiol., 94, 425, 10.1099/00221287-94-2-425 Bendich, 1963, Action of hydroxylamines on DNA and chromosomes, 22, 582 Berger, 1975, Localized mutagenesis of the aroe-stra section of the Escherichia coli chromosome coding for ribosomal proteins, Mol. Gen. Genet., 141, 207, 10.1007/BF00341800 Bhattacharya, 1972, Action of hydroxylamine hydrochloride on the spermatocyte chromosomes of a grasshopper, 59/3, 480 Bingham, 1976, Heat mutagenesis in bacteriophage T4; Transversion pathway, 73, 4159 Borgert, 1971, Effect of inactivation by hydroxylamine on early functions of poliovirus, J. Virol., 8, 1, 10.1128/JVI.8.1.1-6.1971 Borgert, 1971, Early functions of poliovirus, 2. The RNA replication of hydroxylamine-inactivated polioviruses, Z. Naturforsch., 26, 934, 10.1515/znb-1971-0916 Bornestein, 1970, The specific nonenzymatic cleavage of bovine ribonucleuase with hydroxylamine, J. Biol. Chem., 245, 4854, 10.1016/S0021-9258(18)62873-X Bose, 1975, Effect of dimethyl sulfoxide, ethylene glycol and hydroxylamine on tomato (Lycopersicon esculentum Mill), Sci. Cult., 41, 240 Bose, 1975, Effect of colchicine and hydroxylamine in jute (Corchorus olitorius L.), Sci. Cult., 41, 407 Bose, 1975, Preliminary studies on post-irradiation treatments with hydroxylamine and ethylenimine on germination, seeding growth and mitotic aberrations in three varieties of tomato (Lycopersicon esculentum mill), Sci. Cult., 41, 397 Bose, 1975, Effect of dimethyl sulfoxide, ethylene glycol, hydroxylamine and triethanolamine in M1 generation in cluster bean, Bull. Bot. Soc. Bengal., 29, 49 Brandt, 1972, The value of hydroxyurea in assessing repair synthesis of DNA in HeLa cells, Chem.-Biol. Interact., 5, 327, 10.1016/0009-2797(72)90072-5 Breckenridge, 1970, Genetic analysis of streptomycin resistance in Escherichia coli, Genetics, 65, 9, 10.1093/genetics/65.1.9 Bresler, 1974, Inactivation of transfecting DNA by physical and chemical agents; Influence of genotypes of phage lambda and host cells, Mutation Res., 25, 235, 10.1016/0027-5107(74)90052-9 Broegger, 1971, Chromosome damage in human cells induced by hydroxylamine, Hereditas, 69, 19, 10.1111/j.1601-5223.1971.tb02414.x Brown, 1968, The tautomeric state of N(4)-hydroxy- and N(4)-aminocytosine derivatives, J. Chem. Soc., 1925 Brown, 1971, The reaction of adenosine with hydroxylamine, Biochim. Biophys. Acta, 247, 514, 10.1016/0005-2787(71)90687-3 Brown, 1972, The distribution and localization of drug-induced secondary constrictions in human chromosomes, Can. J. Genet. Cytol., 14, 81, 10.1139/g72-011 Brown, 1965, Mechanism of the mutagenic action of hydroxylamine, J. Mol. Biol., 11, 663, 10.1016/S0022-2836(65)80024-9 Brown, 1965, Nucleotides, XLVIII. The reaction of hydroxylamine with cytosine and related compounds, J. Chem. Soc., 208, 10.1039/jr9650000208 Brown, 1972, The synthesis of some 1-substituted cytosine and uracil derivatives, J. Chem. Soc., Perkin Trans., 1, 2385, 10.1039/p19720002385 Budowsky, 1976, Mechanism of the mutagenic action of hydroxylamines, Progr. Nucleic Acid Res. Mol. Biol., 16, 125, 10.1016/S0079-6603(08)60757-6 Budowsky, 1978, Mechanism of the mutagenic action of hydroxylamine, 12. Phenotypic suppression of amber mutants of phage T7 by hydroxylamine and O-methylhydroxylamine, Mutation Res., 49, 163, 10.1016/0027-5107(78)90153-7 Budowsky, 1978, Mechanism of the mutagenic action of hydroxylamine, 13. Reversion of phage MS2 amber mutants in the presence of hydroxylamines, Mutation Res., 49, 173, 10.1016/0027-5107(78)90154-9 Budowsky, 1974, Action of mutagens on MS2 phage and on its infective RNA, 5. Kinetics of the chemical and functional changes of the genome under hydroxylamine treatment, Mutation Res., 24, 245, 10.1016/0027-5107(74)90173-0 Budowsky, 1976, Induced formation of covalent bonds between nucleoprotein components, V. UV- or bisulfite-induced polynucleotide—protein crosslinkage in bacteriophage MS2, Nucleic Acid Res., 3, 261, 10.1093/nar/3.1.261 Budowsky, 1969, Mechanism of the mutagenic action of hydroxylamine, II. Reaction of hydroxylamine with the adenine nucleus, J. Mol. Biol., 44, 205, 10.1016/0022-2836(69)90415-X Budowsky, 1971, Mechanism of the mutagenic action of hydroxylamine, 4. Reaction of hydroxylamine and O-methylhydroxylamine with the adenine nucleus, Biochim. Biophys. Acta, 246, 320, 10.1016/0005-2787(71)90141-9 Budowsky, 1968, Mechanism and kinetics of the reaction of hydroxylamine and O-methylhydroxylamine with the cytosine ring, Mol. Biol., 2, 329 Budowsky, 1971, Mechanism of the mutagenic action of hydroxylamine, 3. Reaction of hydroxylamine and O-methylhydroxylamine with the cytosine nucleus, Biochim. Biophys. Acta, 246, 300, 10.1016/0005-2787(71)90140-7 Carlton, 1969, The isolation and genetic characterization of mutants of the tryptophan system of Bacillus subtilis, Genetics, 62, 445, 10.1093/genetics/62.3.445 Childs, 1977, Conditional lethal mutants of bacteriophage T4 unable to grow on a streptomycinresistant mutant of Escherichia coli, Mutation Res., 44, 165, 10.1016/0027-5107(77)90074-4 Childs, 1973, Superinfection exclusion by incomplete genomes of bacteriophage T4, J. Virol., 11, 1, 10.1128/JVI.11.1.1-8.1973 Chu, 1973, Effect of nitrogen and of catalase on hydroxylamine and hydrazine mutagenesis, Mutation Res., 20, 265, 10.1016/0027-5107(73)90196-6 Cohn, 1964, Similar cytological effects of hydroxylamine and 5-FUdR, agents with different modes of action, Experientia, 20, 158, 10.1007/BF02150712 Cohn, 1964, Effect of hydroxylamine on the rejoining of X-ray-induced chromatid breaks in Vicia faba, Mutation Res., 1, 409, 10.1016/0027-5107(64)90034-X De Goede, 1973, Genetic fine structure of the glycosyltransferase gene of bacteriophage T2, Mutation Res., 19, 11, 10.1016/0027-5107(73)90108-5 De Serres, 1967, Relation between type of base-pair transition and complementation pattern in nitrous acid-induced Ad. 3B mutants of Neurospora crassa, Genetics, 56, 555 Dhillon, 1974, N-Methyl-N′-nitro-N-nitrosoguanidine- and hydroxylamine-induced mutants of the RII region of phage T4, Mutation Res., 22, 223, 10.1016/0027-5107(74)90023-2 Di Mayorca, 1969, Temperature-sensitive mutants of polyoma virus, Virology, 38, 126, 10.1016/0042-6822(69)90134-2 Dobias, 1975, Effect of O-methylhydroxylamine on lambda phage, Folia Microbiol. (Prague), 20, 93 Dowding, 1973, Temperate bacteriophages for Streptomyces coelicolor Ad(2) isolated from soil, J. Gen. Microbiol., 78, 349, 10.1099/00221287-78-2-349 Drake, 1970 Drake, 1970, Suppression of chemical mutagenesis in bacteriophage T4 by genetically modified DNA polymerases, 66, 823 Dubnau, 1976, Conditional mutations in the translational apparatus of Bacillus subtilis, Mol. Gen. Genet., 147, 1, 10.1007/BF00337929 Dzhanpoladyan, 1969, Mutagenic action of ultraviolet rays and some chemical compounds on E. coli CA 265, 21 Eisenstark, 1964, Chemically induced reversions in the cysc region of Salmonella typhimurium, Genetics, 49, 343, 10.1093/genetics/49.2.343 Engel, 1967, The action of thioguanine, hydroxylamine and 5-bromodeoxyuridine on human chromosomes in vitro, Mutation Res., 4, 353, 10.1016/0027-5107(67)90030-9 Esinger, 1972, Selection and preliminary characterization of temperature-sensitive mutants of type 5 adenovirus, J. Virol., 10, 328, 10.1128/JVI.10.3.328-339.1972 Fahmy, 1970, Hydroxylamine and derivatives; Cytotoxicity without mutagenicity in cellular genetic systems, Chem.-Biol. Interact., 2, 331, 10.1016/0009-2797(70)90055-4 Feiss, 1980, On inactivation of bacteriophage lambda by hydroxylamine, Mutation Res., 69, 225, 10.1016/0027-5107(80)90087-1 Flavell, 1974, Site-directed mutagenesis; Generation of an extracistronic mutation in bacteriophage Qβ RNA, J. Mol. Biol., 89, 255, 10.1016/0022-2836(74)90517-8 Fraenkel-Conrat, 1972, The chemical basis for the mutagenicity of hydroxylamine and methoxyamine, Biochim. Biophys. Acta, 262, 264, 10.1016/0005-2787(72)90262-6 Freese, 1961, Transitions and transversions induced by depurinating agents, 47, 540 Freese, 1966, Induction of pure mutant clones by repair of inactivating DNA alterations in phage T4, Genetics, 54, 1055, 10.1093/genetics/54.5.1055 1971, 1 Freese, 1961, The chemical and mutagenic specificity of hydroxylamine, 47, 845 Freese, 1965, The oxygen effect of deoxyribonucleic acid inactivation by hydroxylamines, Biochem., 4, 2419, 10.1021/bi00887a023 Freese, 1966, The oxygen-dependent reaction of hydroxylamine with nucleotides and DNA, Biochim. Biophys. Acta, 123, 17, 10.1016/0005-2787(66)90154-7 Fukuyama, 1968, Mechanism of hydroxylamine inhibition of xanthosine 5′-phosphate aminase, J. Biol. Chem., 243, 5798, 10.1016/S0021-9258(18)91934-4 Galukyan, 1978, Mutability differences in some species of Rudbekii, Biol. Zh. Arm., 31, 335 Gasc, 1972, Hydroxylamine-induced mutagenesis in pneumococcal DNA, C.R. Hebd. Seances Acad. Sci., Ser., D 275, 285 Goldberg, 1969, New Mutations in the S cistron of bacteriophage lambda affecting host cell lysis, Virology, 38, 200, 10.1016/0042-6822(69)90148-2 Goldfarb, 1966, Localization of H+ mutations of T2 phage induced by various mutagens, Sov. Gent., 2, 19 Goncharova, 1969, Comparative study of the genetic effect of hydroxylamine and certain of its analogs on Drosophila Dokl, Akad. Nauk B. SSR, 13, 1124 Goud, 1968, Effectiveness of different mutagens in single and combined treatments, Genetica (The Hague), 39, 229 Guglielminetti, 1967, Analysis of the mosaicism induced by hydroxylamine and nitrous acid in Schizosaccharomyces pombe, Mutation Res., 4, 441, 10.1016/0027-5107(67)90006-1 Gustafsson, 1978, Temperature-dependent and amber copy mutants of plasmid R1DRD-19 in Escherichia coli, Plasmid, 1, 134, 10.1016/0147-619X(78)90034-3 Hama, 1972, Temperature-sensitive mutants of human adenovirus type 12, J. Microbiol., 16, 337 Hashimoto, 1976, Isolation of temperature-sensitive mutants of R plasmid by in vitro mutagenesis with hydroxylamine, J. Bacteriol., 127, 1561, 10.1128/JB.127.3.1561-1563.1976 Havender, 1970, Genetic and transfection studies with B. subtilis phage SP 50, II. Temperature-sensitive mutants and the establishment of a linkage map, Mol. Gen. Genet., 108, 61, 10.1007/BF00343185 Hawthorne, 1969, Identification of nonsense codons in yeast, J. Mol. Biol., 43, 71, 10.1016/0022-2836(69)90079-5 Hayatsu, 1978, Cooperative mutagenic actions of bisulfite and hydroxylamines, Mutation Res., 54, 211, 10.1016/0165-1161(78)90046-8 Heard, 1980, Requirement of a partially diploid donor for the chemical induction of mutations in transforming DNA, Mutation Res., 69, 217, 10.1016/0027-5107(80)90086-X Herrington, 1973, Mutagenesis of bacteriophage PBS2, Mutation Res., 20, 275, 10.1016/0027-5107(73)90198-X Holden, 1976, Escherichia coli mutants deficient in guanine-xanthine phosphoribosyltransferase, J. Bacteriol., 126, 1141, 10.1128/JB.126.3.1141-1148.1976 Holliday, 1962, Mutation and replication in Ustilago maydis, Genet. Res., 3, 472, 10.1017/S0016672300003323 Hong, 1971, Localized mutagenesis of any specific small region of the bacterial chromosome, 68, 3158 Howard, 1964, Identification of the altered bases in mutated single-stranded DNA, 3. Mutagenesis by ultraviolet light, J. Mol. Biol., 9, 372, 10.1016/S0022-2836(64)80214-X Howard-Flanders, 1973, DNA repair and recombination, Br. Med. Bull., 29, 226, 10.1093/oxfordjournals.bmb.a071012 Howard-Flanders, 1968, DNA repair, Annu. Rev. Biochem., 37, 175, 10.1146/annurev.bi.37.070168.001135 Hutchinson, 1977, Mutagenesis of lambda phage; 5-Bromouracil and hydroxylamine, Mol. Gen. Genet., 152, 29, 10.1007/BF00264936 Ishibashi, 1971, Temperature-sensitive conditional-lethal mutants of an avian adenovirus (Celo), Virology, 45, 42, 10.1016/0042-6822(71)90111-5 Ishii, 1975, Comparative analysis of deletion and basepchange mutabilities of Escherichia coli B strains differing in DNA repair capacity (wild-type, wvrA, polA−, recA−) by various mutagens, Mutation Res., 27, 27, 10.1016/0027-5107(75)90271-7 Ishizawa, 1971, Mutagenesis of bacteriophage T4 by a carcinogen, 4-nitroquinoline 1-oxide, Mutation Res., 12, 1, 10.1016/0027-5107(71)90065-0 Jain, 1968, Base specific chemicals and mutation analysis in Lycopersicon, Heredity, 23, 247, 10.1038/hdy.1968.32 Jain, 1966, Differential response of some tomato genes to base-specific mutagens, Nature (London), 211, 652, 10.1038/211652a0 Jain, 1972, Locus specificity of mutagens in Drosophila, Mutation Res., 14, 440, 10.1016/0027-5107(72)90143-1 Jana, 1974, Combined mutagenic effects of X-rays and chemicals in pulse legumes, Radiation Res., 59, 154 Jana, 1974, Hydroxylamine-induced chromosome aberrations in Lens esculenta and combined effects with ionizing radiation, Cytologia, 39, 655, 10.1508/cytologia.39.655 Janion, 1969, Mechanism of hydroxylamine mutagenesis; Complexing properties of copolymers of hydroxycytidylic acid with cytidylic or uridylic acids, Acta Biochim. Pol., 16, 219 Kalinin, 1976, Inactivation of purified bacteriophage lambda DNA under the effect of physical and chemical agents; Effect of phage genotype and host cell, Mol. Mekh. Genet. Protsessov., 199 Kao, 1969, Genetics of somatic mammalian cells, 9. Quantitation of mutagenesis by physical and chemical agents, J. Cell Physiol., 74, 245, 10.1002/jcp.1040740305 Kaplan, 1954, The action of hydroxylamine and cyanide on alcohol dehydrogenase of horse liver, J. Biol. Chem., 211, 419, 10.1016/S0021-9258(18)71232-5 Kaplan, 1963, Different “spectra” of mutant types by extracellular treatment of phage kappa with differing mutagens, Nature (London), 199, 932, 10.1038/199932a0 Kaplan, 1974, Electiveness of repair of plaque-type mutations induced by hydroxylamine in phage kappa of Serratia, Mutation Res., 22, 95, 10.1016/0027-5107(74)90088-8 Kathmann, 1975, Characterization of temperature-sensitive mutants of adenovirus type 2, Hoppe-Seylers Z, Physiol. Chem., 356, 243 Kaul, 1975, Thiol modification of the biological damage of some non-alkylating mutagens, Sci. Cult., 41, 82 Kejzlarova, 1970, Genetic map of bacteriophage alpha, J. Virol., 6, 49, 10.1128/JVI.6.1.49-57.1970 Khomutov, 1968, 631 Khvostova, 1973, The problem of “directed” mutations in chemical mutagenesis, Mutation Res., 21, 37, 10.1016/0165-7992(73)90052-3 Kiefer, 1973, Effect of some nucleic acid binding metabolic inhibitors on split-dose sparing in UV- and electron-irradiated diploid yeast, Int. J. Radiation Biol., 24, 93, 10.1080/09553007314550861 Kilbey, 1976, Comparative aspects of mutagenesis in Drosophila and eukaryotic microorganisms, Hereditas, 82, 43, 10.1111/j.1601-5223.1976.tb01536.x Kimball, 1975, Tests for the mutagenic action of a number of chemicals on Haemophilus influenzae with special emphasis on hydrazine, Mutation Res., 30, 9, 10.1016/0027-5107(75)90248-1 Kimura, 1972, Isolation and characterization of temperature-sensitive mutants of Simian virus 40, Virology, 49, 394, 10.1016/0042-6822(72)90492-8 Klein, 1970, Inhibition of peptide-chain initiation in Escherichia coli by hydroxylamine and effects on ribonucleic acid synthesis, Biochemistry, 9, 4542, 10.1021/bi00825a013 Klein, 1966, Induction with nitrous acid of dextran sulfate resistance in type 1 poliovirus, Virology, 30, 145, 10.1016/S0042-6822(66)81019-X Klein, 1968, Induction with hydroxylamine of guanidine resistance in poliovirus, Virology, 35, 610, 10.1016/0042-6822(68)90290-0 Kleinhofs, 1975, Azide mutagenesis; In vitro studies, Mutation Res., 29, 497, 10.1016/0027-5107(75)90069-X Kochetkov, 1969, The chemical modification of nucleic acids, Progr. Nucleic Acid Res. Mol. Biol., 9, 403, 10.1016/S0079-6603(08)60773-4 Kondo, 1974, Environmental mutagen testing in Escherichia coli and phage lambda, Mutation Res., 26, 235, 10.1016/S0027-5107(74)80020-5 Konickova, 1970, Mutagenic processes in Mycobacterium phlei, Folia Microbiol. (Prague), 15, 205 Konickova-Radochova, 1970, A comparative study of mutagenesis in acid-fast and non-acid-fast strains of Mycobacterium phlei, Folia Microbiol. (Prague), 15, 192, 10.1007/BF02873083 Konickova-Radochova, 1970, The study of mutagenesis in Mycobacterium phlei, Folia Microbiol. (Prague), 15, 88, 10.1007/BF02880090 Konickova-Radochova, 1968, Mutagenic effect of hydroxylamine on Mycobacterium phlei strain PA, Folia Microbiol. (Prague), 13, 226, 10.1007/BF02871038 Koudelka, 1975, Mutagenic effect of O-methylhydroxylamine on phage T4, Folia Microbiol. (Prague), 20, 93 Kozak, 1970, Activity of some agents in the lysogenic induction in Corynebacterium diphtheriae strain No. 25, Bull. Acad. Pol. Sci., Ser. Sci. Biol., 18, 445 Kriviskii, 1970, Lethal and mutagenic effects during the combined action of UV irradiation and hydroxylamine on extracellular bacteriophage, Sov. Genet., 6, 616 Lake, 1975, A genetic recombination map of foot-and-mouth disease virus, J. Gen. Virol., 27, 355, 10.1099/0022-1317-27-3-355 Lawley, 1967, J. Mol. Biol., 24, 75, 10.1016/0022-2836(67)90091-5 Ledinko, 1973, Enhancement of adenovirus transformation of hamster cells by N-methyl-N′-nitro-N-nitrosoguanidine, caffeine and hydroxylamine, Cancer Res., 33, 2936 Lieberman, 1956, Enzymatic synthesis of adenosine-5′-phosphate from inosine-5′-phosphate, J. Biol. Chem., 223, 327, 10.1016/S0021-9258(18)65142-7 Lindahl, 1970, Bacteriophage P2: Replication of the chromosome requires a protein which acts only on the genome that coded for it, Virology, 42, 522, 10.1016/0042-6822(70)90295-3 Loprieno, 1967, Intragenic mapping of chemically induced AD-7 mutants of Schizosaccharomyces pombe, J. Bacteriol., 94, 1162, 10.1128/JB.94.4.1162-1165.1967 Loprieno, 1969, Evaluation of genetic alterations induced by chemical mutagens in Schizosaccharomyces pombe, Mutation Res., 8, 65, 10.1016/0027-5107(69)90141-9 Lyons, 1972, The genetic map of the filamentous bacteriophage F1, Virology, 49, 45, 10.1016/S0042-6822(72)80006-0 Mackenzie, 1970, Isolation of temperature-sensitive mutants and the construction of a preliminary genetic map for influenza virus, J. Gen. Virol., 6, 63, 10.1099/0022-1317-6-1-63 Macneil, 1978, Fine-structure mapping and complementation analysis of NIF (nitrogen fixation) genes in Klebsiella pneumoniae, J. Bacteriol., 136, 253, 10.1128/JB.136.1.253-266.1978 Maes, 1972, Investigations of the attenuation induced in foot-and-mouth disease virus by a chemical mutagen, Arch. Gesamte Virusforsch., 37, 19, 10.1007/BF01241147 Malling, 1971, Hydroxylamine-induced purple mutants (AD-3) in Neurospora crassa, 2. Identification of genetic alteration at the molecular level, Hereditas, 68, 219, 10.1111/j.1601-5223.1971.tb02398.x Malling, 1967, Mutagenicity of methylhydroxylamines in Neurospora crassa, Mutation Res., 4, 559, 10.1016/0027-5107(67)90042-5 Malling, 1967, The mutagenicity of the acridine mustard (ICR-170) and the structurally related compounds in Neurospora, Mutation Res., 4, 265, 10.1016/0027-5107(67)90021-8 Malling, 1966, Hydroxylamine as a mutagenic agent for Neurospora crassa, Mutation Res., 3, 470, 10.1016/0027-5107(66)90071-6 Malling, 1967, Relation between complementation patterns and genetic alterations in nitrous acid-induced Ad-3B mutants of Neurospora crassa, Mutation Res., 4, 425, 10.1016/0027-5107(67)90005-X Malling, 1971, Hydroxylamine-induced purple adenine (Ad-3) mutants in Neurospora crassa, 1. Characterization of mutants by genetic tests, Mutation Res., 12, 35, 10.1016/0027-5107(71)90070-4 Malling, 1968, Correlation between base-pair transition and complementation pattern in nitrous acid-induced Ad-3B mutants of Neurospora crassa, Mutation Res., 5, 359, 10.1016/0027-5107(68)90006-7 Mamalyga, 1974, Variability of hard spring wheat under the action of various mutagenic factors, Cytol. Genet. (U.S.S.R.), 8, 15 Mamalyga, 1974, Induced chlorophyll mutations in hard spring wheat, Dokl. Biol. Sci., 215, 126 Mamalyga, 1977, Relative efficiency of various mutagens in inducing mutations of value in selection in hard spring wheat, Cytol. Genet. (U.S.S.R.), 11, 32 Mamalyga, 1976, Hereditary variation of spring durum wheat induced by chemical and physical mutagens, Sov. Genet., 12, 145 Manthey, 1975, Chemical induction of lysogeny of Staphylococcus aureus, Zbl. Bakteriol. Parasitenk. Abt. I, Orig. A, 231, 369 Markushin, 1973, Genetic classification and biological properties of temperature-sensitive mutants of fowl plague virus, Acta Virol., 17, 369 Masamune, 1971, A mutant of bacteriophage T7 deficient in polynucleotide ligase, J. Biol. Chem., 246, 6874, 10.1016/S0021-9258(19)45927-9 Mauro, 1970, Age responses of cultured mammalian cells to cytotoxic drugs, Cancer Res., 30, 1397 McCahon, 1977, Extended genetic recombination map for foot-and-mouth disease virus, J. Gen. Virol., 35, 555, 10.1099/0022-1317-35-3-555 Meyer, 1976, Mutagenesis in bacteriophage T7; 1. Chemically induced mutagenesis, Z. Allgem. Mikrobiol., 16, 279, 10.1002/jobm.3630160407 Mills, 1969, The induction and characterization of recessive suppressors of Arg-2 in Schizophyllum commune, Mol. Gen. Genet., 104, 313, 10.1007/BF00334230 Mironescu, 1969, Nucleolar and mitotic abnormalities produced by thioacetamide and hydroxylamine in monkey kidney cells cultivated in vitro, Exp. Cell Res., 57, 193, 10.1016/0014-4827(69)90141-4 Moon, 1973, Sequence of bovine liver glutamate dehydrogenase, J. Biol. Chem., 248, 3082, 10.1016/S0021-9258(19)44011-8 Moore, 1975, Distribution of alleles of diverse mutagenic origins in the allele map of the FTR cistron, Mutation Res., 28, 455, 10.1016/0027-5107(75)90239-0 Moreno, 1974, Suppressor-sensitive mutants and genetic map of Bacillus subtilis bacteriophage Ph129, Virology, 62, 1, 10.1016/0042-6822(74)90298-0 Morosova, 1964, A study of the effect of hydroxylamine on native and denatured DNA, Biokhimiya, 29, 13 Mukai, 1969, The mutagenicity and initiating activity of some aromatic amine metabolites, Ann. N.Y. Acad. Sci. (U.S.A.), 163, 828, 10.1111/j.1749-6632.1969.tb24902.x Murata, 1971, Temperature-sensitive mutants of phage J1 of Lactobacillus casei; Their isolation and temperature-sensitive step of their growth, Nippon Nogei kagaku Kaishi (J. Agr. Chem. Soc. Jpn.), 45, 321, 10.1271/nogeikagaku1924.45.321 Murgola, 1974, Suppression of glutamic acid codons by mutant glycine transfer ribonucleic acid, J. Bacteriol., 117, 439, 10.1128/JB.117.2.439-443.1974 Nakagawa, 1971, Effects of polyhydroxybenzoate derivatives in cells in vitro, Osaka Daigaku Igaku Zasshi (J. Osaka Univ. Fac. Med.), 23, 123 Nakai, 1976, Triple rad mutant of yeast as an indicator strain for detection of environmental mutagens, Mutation Res., 38, 344, 10.1016/0165-1161(76)90172-2 Nakai, 1978, Investigation on the tester strain of Saccharomyces cerevisiae for primary screening of environmental mutagens, Mutation Res., 53, 240, 10.1016/0165-1161(78)90302-3 Nasim, 1967, The induction of replicating instabilities by mutagens in Schizosaccharomyces pombe, Mutation Res., 4, 753, 10.1016/0027-5107(67)90084-X Nasim, 1967, Origin of complete and mosaic mutants from mutagenic treatment of single cells, Mutation Res., 4, 1, 10.1016/0027-5107(67)90104-2 Nasim, 1977, Induction of mutations by chemicals and gamma rays in mutants of yeast refractory to UV mutagenesis, Can. J. Genet. Cytol., 19, 323, 10.1139/g77-035 Nasim, 1970, Inactivation and the induction of lethal sectoring by chemical mutagens in yeast, Can. J. Genet., Cytol., 12, 10, 10.1139/g70-002 Natarajan, 1964, Localized chromosome breakage induced by ethyl methane-sulphonate and hydroxyalamine in Vicia faba, Chromosoma, 15, 156, 10.1007/BF00285727 Nesterova, 1971, Spontaneous and induced mutations in the H gene of T2H phage, Microbiology (U.S.S.R.), 40, 86 Nixon, 1970, Inhibition of peptide chain initiation in Escherichia coli by hydroxylamine; Reaction of hydroxylamine with folate coenzymes, Biochemistry, 9, 4833, 10.1021/bi00827a001 Nicoloff, 1971, On the induction of chromosome structural changes by hydroxyalamine in Vicia faba, Mutation Res., 13, 215, 10.1016/0027-5107(71)90108-4 Noonan, 1978, Temperature-sensitive mutants of Simian virus 40, I. Isolation and preliminary characterization of B/C gene mutants, Intervirology, 10, 181, 10.1159/000148982 Northrop, 1968, Appearance of virulent bacteriophages in lysogenic E coli cultures after prolonged growth in the presence of triethylenemelamine, J. Gen. Physiol., 52, 136, 10.1085/jgp.52.1.136 Ohnishi, 1971, Growth inhibition and appearance of the membranous structure in Escherichia coli infected with bacteriophage FD, J. Virol., 7, 673, 10.1128/JVI.7.5.673-678.1971 Okubo, 1968, Isolation of suppressor mutant in Bacillus subtilis, J. Bacteriol., 95, 1187, 10.1128/JB.95.3.1187-1188.1968 Oppenheim, 1965, Induction of chromosome breaks in cultured normal human leukocytes by potassium arsenite, hydroxyurea and related compounds, Cancer Res., 25, 980 Panfilova, 1973, Changes in the frequency and spectra of auxotrophic mutations in E. coli under the combined action of chemical mutagens and UV light, Stud. Biophys., 36/37, 355 Panfilova, 1966, Study of the joint action of chemical mutagens and ultraviolet rays upon the appearance of back mutations in Escherichia coli, Sov. Genet., 2, 35 Parker, 1969, Fine-structure mapping and mutational studies of gene controlling yeast cytochrome C, Genetics, 62, 9, 10.1093/genetics/62.1.9 Parodi, 1977, Relationships between mutation and transformation frequencies in mammalian cells treated “in vitro” with chemical carcinogens, Mutation Res., 47, 53, 10.1016/0165-1110(77)90017-3 Paronikyan, 1975, Mutagenic effects of new chemical compounds, 3. Study of the mutagenic action of certain hydroxylamine derivatives, Sov. Genet., 11, 1296 Peterson, 1975, Reversion of the 8-azaguanine resistant phenotype of variant Chinese hamster cells treated with alkylating agents and 5-bromo-2′-deoxyuridine, Mutation Res., 29, 127, 10.1016/0027-5107(75)90026-3 Peterson, 1974, Influence of serum components on the growth and mutation of Chinse hamster cells in medium containing aminopterin, Mutation Res., 24, 25, 10.1016/0027-5107(74)90043-8 Phillips, 1967, The mutagenic action of hydroxylamine, Progr. Nucleic Acid Res. Mol. Biol., 7, 349, 10.1016/S0079-6603(08)60956-3 Piruzyan, 1970, Study of intragenic specificity of the action of mutagens on amber mutants of gene 43 of bacterial phage T4B, Sov. Genet., 6, 1617 Pogosov, 1968, Fine structure of the gene controlling DNA-polymerase synthesis in T4B bacteriophage, Sov. Genet., 4, 1543 Pons, 1973, Formation of pure and mixed clones of C mutants in Serratia phage sigma after treatment of the free virion with UV or hydroxylamine, Mutation Res., 20, 149, 10.1016/0027-5107(73)90185-1 Poslovina, 1973, Study of the mutagenic action of N4-hydroxycytidine produced by modifying cytidine with hydroxylamine, on Escherichia coli B, Sov. Genet., 9, 590 Putrament, 1973, Mutagenic action of hydroxylamine and methoxyamine on yeast, 1. Hydroxylamine, Mol. Gen. Genet., 122, 1, 10.1007/BF00337975 Putrament, 1971, Induction of intragenic mitotic recombination in yeast by hydroxylamine and its mutagenic specificity, Mol. Gen. Genet., 111, 89, 10.1007/BF00286558 Radford, 1972, Restoration of a single enzyme function in bifunctionally defective non-polar pyrimidine-3 mutants of Neurospora, Mutation Res., 15, 23, 10.1016/0027-5107(72)90088-7 Rajchert-Trzpil, 1968, Influence of mutagenic agents on the integration of the F episome into the chromosome of Escherichia coli K-12 F+, J. Gen. Microbiol., 54, 47, 10.1099/00221287-54-1-47 Ramachandran, 1958, Reactions involving the amide and carboxyl groups of tobacco mosaic virus (TMV) protein, Biochim. Biophys. Acta, 30, 616, 10.1016/0006-3002(58)90109-4 Ramaiya, 1969, The cytogenetic effect of N-nitrosoethylurea, hydroxylamine and X-rays on the germ cells of male mice, Sov. Genet., 5, 188 Ramaiya, 1968, Comparative analysis of the effects of N-nitrosoethylurea, hydroxylamine and X-rays on the fertility of male mice, Sov. Genet., 4, 1041 Ratho, 1971, Method of inducing awnless condition in rice by chemical mutagenesis, Curr. Sci., 40, 274 Ravin, 1974, Fine structure of the lysozyme gene of bacteriophage T4B, Mol. Gen. Genet., 128, 359, 10.1007/BF00268523 Rhaese, 1968, Chemical analysis of DNA alterations, 1. Base liberation and backbone breakage of DNA and oligodeoxyadenylic acid induced by hydrogen peroxide and hydroxylamine, Biochim. Biophys. Acta, 155, 476, 10.1016/0005-2787(68)90193-7 Richardson, 1969, Enzymes in DNA metabolism, Annu. Rev. Biochem., 38, 795, 10.1146/annurev.bi.38.070169.004051 Rieger, 1973, Selective effects of chemical mutagens on the chromosomes of Vicia faba as influenced by segment transpositions, Mutation Res., 21, 232, 10.1016/0165-1161(73)90249-5 Ripley, 1972, A genetic assay for transversion mutations in bacteriophage T4, Mol. Gen. Genet., 118, 1, 10.1007/BF02428327 Reddy, 1974, Interaction of certain base-specific chemicals and diethyl sulfate in the induction of chlorophyll mutations in Oryza sativa, Mutation Res., 22, 127, 10.1016/0027-5107(74)90092-X Reddy, 1973, Mutational studies with some base-specific chemicals in Oryza sativa, Indian J. Exp. Biol., 11, 222 Rosenkranz, 1966, An alteration of the DNA isolated from Escherichia coli treated with hydroxylamine, Biochim. Biophys. Acta, 119, 434, 10.1016/0005-2787(66)90209-7 Ronen, 1976, Mutagen specificity and position effects on mutation in T4RII nonsense sites, Mutation Res., 34, 21, 10.1016/0027-5107(76)90258-X Ronen, 1971, Genetic distances separating adjacent base pairs in bacteriophage T4, Virology, 45, 496, 10.1016/0042-6822(71)90349-7 Rosenkranz, 1974, Studies on the bacteriostatic action of hydroxylamine, Biochim. Biophys. Acta, 87, 40 Salganik, 1972, Some possibilities of mutation control concerned with local increase of DNA sensitivity to chemical mutagens, Biol. Zentralbl., 91, 49 Salts, 1971, Neighbor effects in the mutation of ochre triplets in the T4RII gene, Mutation Res., 13, 109, 10.1016/0027-5107(71)90002-9 Sato, 1976, Studies on temperature-dependent ultraviolet light-sensitive mutants of bacteriophage T4; Structural gene for T4 endonuclease 5, J. Mol. Biol., 102, 15, 10.1016/0022-2836(76)90071-1 Savage, 1971, Morphology, physiology and virulence of some mutants of Candida albicans, Infect. Immunol., 3, 141, 10.1128/IAI.3.1.141-148.1971 Sayed, 1973, Effect of gamma rays and some chemical mutagens on induction of telotrisomics in Hordeum, Can. J. Genet. Cytol., 15, 815, 10.1139/g73-095 Schuster, 1961, The reaction of tobacco mosaic virus ribonucleic acid with hydroxylamine, J. Mol. Biol., 3, 447, 10.1016/S0022-2836(61)80057-0 Schuster, 1963, The inactivating and mutagenic action of hydroxylamine on tobacco mosaic virus ribonucleic acid, Virology, 19, 421, 10.1016/0042-6822(63)90035-7 Schwartz, 1970, Streptomycin-induced phenotypic suppression of hydroxylamine-induced nonsense mutants in the RII A cistron of bacteriophage T4, J. Virol., 5, 22, 10.1128/JVI.5.1.22-26.1970 Scott, 1970, Clear plaque mutants of phage P1, Virology, 41, 66, 10.1016/0042-6822(70)90054-1 Sebeleva, 1972, Study of protein synthesis in salivary glands of Chironomus, Tsitologiya, 14, 46 Seiler, 1977, Inhibition of testicular DNA synthesis by chemical mutagens and carcinogens, Preliminary results in the validation of a novel short-term test, Mutation Res., 46, 305, 10.1016/0165-1161(77)90007-3 Seiler, 1972, Mutagenic mode of action of benzimidazole, Experientia, 34, 851, 10.1007/BF01939661 Sen, 1972, Chromosomal changes in barley induced by chemical mutagens, Vestsi Akad. Navuk Belarusk. SSR Ser. Biyal. Navuk, 5, 56 Shapiro, 1972, Modification of polyuridylic acid by bisulfite; Effect of double helix formation and coding properties, Biochem. Biophys. Res. Commun., 47, 544, 10.1016/0006-291X(72)90913-8 Sharma, 1976, Some new findings in chemical mutagenesis of higher plants, Indian J. Genet. Plant Breed., 36, 149 Sherman, 1975, Transforming activity of T4R+ phage DNA treated with UV, nitrous acid, hydroxylamine and visible light in the presence of methylene blue, Sov. Genet., 11, 635 Shestakov, 1969, Action of some chemical mutagens on Anacystis nidulans, 75 Shiroki, 1972, Isolation and a preliminary characterization of temperaturesensitive mutants of adenovirus 12, Virology, 49, 1, 10.1016/S0042-6822(72)80002-3 Shiroki, 1974, Analysis of adenovirus 12 temperature-sensitive mutants defective in viral DNA replication, Virology, 61, 474, 10.1016/0042-6822(74)90283-9 Shkvarnikov, 1975, Induction of mutations in wheat, 41(3), 204 Shkvarnikov, 1971, Effect of the combined action of chemical mutagens on chromosomal rearrangements in wheat, Eksp. Mutatsii. Sel. Rosl., 53 Shkvarnikov, 1975, Mutations in maize, induced by chemical mutagens, 41(3), 117 Shkvarnikov, 1976, Induction of mutations in wheat, Indian J. Genet. Plant Breed., 36, 140 Shugar, 1976, Mechanism of hydroxylamine mutagenesis, Crystal structure and conformation of 1,5-dimethyl-N4-hydroxycytosine, Biochim. Biophys. Acta, 447, 274, 10.1016/0005-2787(76)90050-2 Shukla, 1979, Delayed mutagenic action of hydroxylamine in Drosophila, Mutation Res., 61, 399, 10.1016/0027-5107(79)90144-1 Shukla, 1972, Analyais of mutagen specifity in Drosophila melanogaster, Mutation Res., 16, 363, 10.1016/0027-5107(72)90204-7 Sichkar, 1973, Gluten levels in winter wheat mutants, Tsitol. Genet., 7, 220 Sichkar, 1973, Quality of gluten in winter wheat mutants induced by chemical mutagens, Tsitol. Genet., 7, 387 Sineokii, 1976, Genetic study of the bacteriophage PH181, 1. Isolation, study of complex of complementation and preliminary mapping of amber mutants of bacteriophage PH181, Sov. Genet., 12, 982 Singer, 1974, Correlation between amino acid exchanges in coat protein of TMV mutants and the nature of the mutagens, Virology, 60, 485, 10.1016/0042-6822(74)90342-0 Sinha, 1977, Relative effectiveness of mutagens on amylase production of Aspergillus wentii, Indian J. Exp. Biol., 15, 1068 Sitnikov, 1970, Rescue of RCT+40 marker of Vaccinia virus using different methods to inactivate the donor virus, Vopr. Virusol., 15, 278 Smith, 1973, Nonsense suppressors in Saccharomyces cerevisiae, Genetics, 74, S259 Smith, 1971, The nature of lactose operator constitutive mutations, J. Mol. Biol., 59, 273, 10.1016/0022-2836(71)90051-9 Soifer, 1974, Inhibition of DNA synthesis in bacteria after treatment with 1 M hydroxylamine, Dokl. Biochem., 217, 309 Sokova, 1970, Study of the action of gamma rays, hydroxylamine and urethane on the chromosomes of the Dzungarian hamster in vitro, Sov. Genet., 6, 1593 Somers, 1962, Chromosome damage induced by hydroxylamine in mammalian cells, 48, 937 Spatz, 1970, One way to do experiments on gene conversion; transfection with heteroduplex SPP1 DNA, Mol. Gen. Genet., 109, 84, 10.1007/BF00334048 Srinivasachar, 1971, Effect of the mutagens hydroxylamine, ethyl methanesulfonate and gamma rays separately and in combination on meiotic chromosomes, Caryologia, 24, 1, 10.1080/00087114.1971.10796406 Steinschneider, 1972, Nearest-neighbour effects; Reactivity towards methoxyamine of cytidine, cytidine monophosphates and cytidine dinucleoside monophosphates, J. Mol. Biol., 67, 333, 10.1016/0022-2836(72)90245-8 Strack, 1964, Comparison of mutation and inactivation rates induced in bacteriophages and transforming DNA by various mutagens, Mutation Res., 1, 10, 10.1016/0027-5107(64)90048-X Susskind, 1971, Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium, Virology, 45, 638, 10.1016/0042-6822(71)90178-4 Sweet, 1976, Resistance of Micrococcus radiodurans to killing and mutation by agents which damage DNA, Mutation Res., 34, 175, 10.1016/0027-5107(76)90122-6 Takahashi, 1972, Isolation of conditional lethal mutants (temperature-sensitive and host-dependent mutants) of Adenovirus type 5, Virology, 49, 815, 10.1016/0042-6822(72)90540-5 Tan, 1969, Semliki forest virus temperature-sensitive mutants; Isolation and characterization, Virology, 38, 427, 10.1016/0042-6822(69)90155-X Taylor, 1970, Alteration of native DNA transcription by the mutagen hydroxylamine, Cancer Res., 30, 95 Tessman, 1965, Mutagenic effects of hydroxylamine in vivo, Science, 148, 507, 10.1126/science.148.3669.507 Tessman, 1964, Identification of the altered bases in mutated single-stranded DNA, 1. In vitro mutagenesis by hydroxylamine, ethyl methanesulfonate and nitrous acid, J. Mol. Biol., 9, 352, 10.1016/S0022-2836(64)80212-6 Tevethia, 1977, Biology of Simian virus 40 (SV40) transplantation antigen (Trag.); 2. Isolation and characterization of additional temperature-sensitive mutants of SV40, Virology, 81, 192, 10.1016/0042-6822(77)90137-4 Thiry, 1963, Chemical mutagenesis of Newcastle disease virus, Virology, 19, 225, 10.1016/0042-6822(63)90012-6 Tikchonenko, 1971, The secondary structure of bacteriophage DNA in situ, J. Mol. Biol., 55, 535, 10.1016/0022-2836(71)90335-4 Tikchonenko, 1973, Peculiarities of the secondary structure of bacteriophage DNA in situ, J. Mol. Biol., 73, 109, 10.1016/0022-2836(73)90162-9 Tiraby, 1974, Marker discrimination and mutagen-induced alterations in pneumococcal transformation, Genetics, 77, 449, 10.1093/genetics/77.3.449 Travis, 1972, Effects of hydroxylamine and N-methyl-N′-nitro-N-nitrosoguanidine in Mimulus cardinalis (Schrophulariaceae); Survival curves and dominant mutants, Theor. Appl. Genet., 42, 288, 10.1007/BF00277720 Tully, 1977, Fine-structure mapping and complementation analysis of the Escherichia coli CYSB gene, J. Bacteriol., 131, 49, 10.1128/JB.131.1.49-56.1977 Vandamme, 1972, Studies on the bacteriophage MS2, Part 12. Suppressor-sensitive mutants of the A protein cistron, Mol. Gen. Genet., 117, 219, 10.1007/BF00271649 Van Den Ende, 1972, The isolation and characterization of a T4 mutant partially defective in recombination, Mol. Gen. Genet., 116, 239, 10.1007/BF00269768 Vanderbilt, 1972, A. promoter site and polarity gradients in phage S13, Virology, 50, 171, 10.1016/0042-6822(72)90357-1 Vanderbilt, 1970, Mutagenic methods for determining which DNA strand is transcribed for individual viral genes, Nature (London), 228, 54, 10.1038/228054a0 Vanderbilt, 1970, Identification of the altered bases in mutated single-stranded DNA, 4. Nitrous acid induction of the transition guanine to adenine and thymine to cytosine, Genetics, 66, 1, 10.1093/genetics/66.1.1 Van Minderhout, 1975, Nonsense mutants in the bacteriophage T4D V gene, Mutation Res., 29, 333, 10.1016/0027-5107(75)90055-X Van Minderhout, 1976, Evidence for a third type of UV repair in bacteriophage T4, Mutation Res., 35, 161, 10.1016/0027-5107(76)90178-0 Van Vliet, 1978, Virulent mutants of temperate phage MU-1, Mol. Gen. Genet., 160, 195, 10.1007/BF00267481 Vasil'Eva, 1976, Differences in mutagenic efficiency of N-nitrosomethyl- and N-nitrosoethylurea on bacterial DNA in vivo, Sov. Genet., 12, 634 Vasyunina, 1975, Effect of adenine, adenosine and adenylic nucleotides on the mutagenic action of hydroxylamine, Sov. Genet., 11, 376 Vitek, 1974, Hydroxylamine-caused mitotic inhibition of a human neoplastic cell line, Folia Biol. (Prague), 20, 286 Voronina, 1968, The regulation of the mutation spectrum in Escherichia coli by treatment with chemical mutagens at different stages of DNA replication, Sov. Genet., 4, 925 Waldren, 1973, Use of in vitro techniques in mammalian cell biology; Some aspects of the action of caffeine and other agents on cells in culture, Dissertation Abstr. Int. B, 34, 553 Wall, 1974, Phage P1 mutants with altered transducing abilities for Escherichia coli, Virology, 59, 532, 10.1016/0042-6822(74)90463-2 Wang, 1977, Mutagenicity of hydroxamic acids for Salmonella typhimurium, Mutation Res., 56, 7, 10.1016/0027-5107(77)90235-4 Watanabe, 1964, Induction of a mutation in bacteriophages by hyponitrous acid, oxime and hydroxylamine, Enzymologia, 28, 21 Weinberg, 1965, Base analog-induced arabinose-negative mutants of Escherichia coli, Genetics, 51, 545, 10.1093/genetics/51.4.545 Weisburger, 1973, Biochemical formation and pharmacological, toxicological and pathological properties of hydroxylamines and hydroxyamic acids, Pharmacol. Rev., 25, 1 Williams, 1971, Isolation of temperature-sensitive mutants of adenovirus type 5, J. Gen. Virol., 11, 95, 10.1099/0022-1317-11-2-95 Wilson, 1966, The effects of hydroxylamine on the template properties of polycytidylic acid, J. Biol. Chem., 241, 1725, 10.1016/S0021-9258(18)96696-2 Winkler, 1965, Host cell reactivation of chemically induced lethal damage in DNA-containing kappa phages of Serratia, Z. Naturforsch., 20B, 864, 10.1515/znb-1965-0908 Wuesthoff, 1970, Mutations creating internal promoter elements in the tryptophan operon of Salmonella typhimurium, J. Mol. Biol., 49, 171, 10.1016/0022-2836(70)90384-0 Yakovleva, 1977, Induction of single-strand breaks by 1 M hydroxylamine in the DNA of normal bacteria and bacteria defective for UV-specific endonuclease, Stud. Biophys., 62, 9 Yakovleva, 1977, Molecular nature of single-strand and double-strand DNA breaks in Escherichia coli treated by hydroxylamine, Dokl. Vses. Akad. Skh. Nauk, 12, 10 Yamafuji, 1966, Isolation of a pre-viral deoxyribonucleic acid, Nature (London), 210, 1158, 10.1038/2101158a0 Yamafuji, 1964, Metabolic virogens having mutagenic action and chromosomal previruses, Enzymologia, 27, 217 Yamaguchi, 1975, Temperature-sensitive mutants of Simian virus 40 selected by transforming ability, J. Virol., 15, 1297, 10.1128/JVI.15.6.1297-1301.1975 Yamamoto, 1973, Organization and function of bacteriophage T4 tail, 1. Isolation of heat-sensitive T4 tail mutants, Virology, 52, 234, 10.1016/0042-6822(73)90412-1 Zhestyanikov, 1969