The fungal pathogenCryptococcus neoformansmanipulates macrophage phagosome maturation

Cellular Microbiology - Tập 17 Số 5 - Trang 702-713 - 2015
L. Smith1, Emily Dixon1, Robin C. May1,2
1Institute of Microbiology and Infection and School of Biosciences, University of Birmingham, Birmingham, UK
2National Institute of Health Research Surgical Reconstruction and Microbiology Research Centre, Queen Elizabeth Hospital Birmingham, Birmingham, UK

Tóm tắt

Từ khóa


Tài liệu tham khảo

Alanio, 2011, Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans, MBio, 2, 10.1128/mBio.00158-11

Alvarez, 2006, Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages, Curr Biol, 16, 2161, 10.1016/j.cub.2006.09.061

Alvarez-Dominguez, 2008, Characterization of a Listeria monocytogenes protein interfering with Rab5a, Traffic, 9, 325, 10.1111/j.1600-0854.2007.00683.x

Artavanis-Tsakonas, 2006, Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification, Proc Natl Acad Sci USA, 103, 15945, 10.1073/pnas.0607528103

Bain, 2012, Non-lytic expulsion/exocytosis of Candida albicans from macrophages, Fungal Genet Biol, 49, 677, 10.1016/j.fgb.2012.01.008

Bakowski, 2010, The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole, Cell Host Microbe, 7, 453, 10.1016/j.chom.2010.05.011

Barr, 2013, Review series: Rab GTPases and membrane identity: causal or inconsequential?, J Cell Biol, 202, 191, 10.1083/jcb.201306010

Chayakulkeeree, 2011, SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans, Mol Microbiol, 80, 1088, 10.1111/j.1365-2958.2011.07632.x

Chen, 2002, Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes, BMC Cell Biol, 3, 21, 10.1186/1471-2121-3-21

Chen, 2014, The Cryptococcus neoformans transcriptome at the site of human meningitis, MBio, 5, e01087-13, 10.1128/mBio.01087-13

Claus, 1998, Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages. Enrichment of cathepsin H in early endosomes, J Biol Chem, 273, 9842, 10.1074/jbc.273.16.9842

Coers, 1999, Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth, Nat Cell Biol, 1, 451, 10.1038/15687

Cox, 2000, Urease as a virulence factor in experimental cryptococcosis, Infect Immun, 68, 443, 10.1128/IAI.68.2.443-448.2000

Cox, 2001, Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans, Mol Microbiol, 39, 166, 10.1046/j.1365-2958.2001.02236.x

Diamond, 1973, Growth of Cryptococcus neoformans within human macrophages in vitro, Infect Immun, 7, 231, 10.1128/IAI.7.2.231-236.1973

Diamond, 1972, Factors influencing killing of Cryptococcus neoformans by human leukocytes in vitro, J Infect Dis, 125, 367, 10.1093/infdis/125.4.367

Enjalbert, 2007, Niche-specific activation of the oxidative stress response by the pathogenic fungus Candida albicans, Infect Immun, 75, 2143, 10.1128/IAI.01680-06

Feldmesser, 2001, Intracellular parasitism of macrophages by Cryptococcus neoformans, Trends Microbiol, 9, 273, 10.1016/S0966-842X(01)02035-2

Fernandez-Arenas, 2009, Candida albicans actively modulates intracellular membrane trafficking in mouse macrophage phagosomes, Cell Microbiol, 11, 560, 10.1111/j.1462-5822.2008.01274.x

Flannagan, 2012, The cell biology of phagocytosis, Annu Rev Pathol, 7, 61, 10.1146/annurev-pathol-011811-132445

Fratti, 2001, Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest, J Cell Biol, 154, 631, 10.1083/jcb.200106049

Garcia-Rodas, 2011, The interaction between Candida krusei and murine macrophages results in multiple outcomes, including intracellular survival and escape from killing, Infect Immun, 79, 2136, 10.1128/IAI.00044-11

Hernandez, 2004, Salmonella modulates vesicular traffic by altering phosphoinositide metabolism, Science, 304, 1805, 10.1126/science.1098188

Holm, 2001, Leishmania donovani lipophosphoglycan causes periphagosomal actin accumulation: correlation with impaired translocation of PKCalpha and defective phagosome maturation, Cell Microbiol, 3, 439, 10.1046/j.1462-5822.2001.00127.x

Horwitz, 1983, The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes, J Exp Med, 158, 2108, 10.1084/jem.158.6.2108

Jacobson, 1982, Genetic and phenotypic characterization of capsule mutants of Cryptococcus neoformans, J Bacteriol, 150, 1292, 10.1128/JB.150.3.1292-1296.1982

Johnston, 2010, The human fungal pathogen Cryptococcus neoformans escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation, PLoS Pathog, 6, e1001041, 10.1371/journal.ppat.1001041

Kasper, 2014, Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages, PLoS ONE, 9, e96015, 10.1371/journal.pone.0096015

Kechichian, 2007, Depletion of alveolar macrophages decreases the dissemination of a glucosylceramide-deficient mutant of Cryptococcus neoformans in immunodeficient mice, Infect Immun, 75, 4792, 10.1128/IAI.00587-07

Kinchen, 2008, Phagosome maturation: going through the acid test, Nat Rev Mol Cell Biol, 9, 781, 10.1038/nrm2515

Lennon-Dumenil, 2002, Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation, J Exp Med, 196, 529, 10.1084/jem.20020327

Levitz, 1999, Cryptococcus neoformans resides in an acidic phagolysosome of human macrophages, Infect Immun, 67, 885, 10.1128/IAI.67.2.885-890.1999

Lorenz, 2004, Transcriptional response of Candida albicans upon internalization by macrophages, Eukaryot Cell, 3, 1076, 10.1128/EC.3.5.1076-1087.2004

Ma, 2006, Expulsion of live pathogenic yeast by macrophages, Curr Biol, 16, 2156, 10.1016/j.cub.2006.09.032

Malik, 2003, Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase, J Immunol, 170, 2811, 10.4049/jimmunol.170.6.2811

Mansour, 2011, Dynamic virulence: real-time assessment of intracellular pathogenesis links Cryptococcus neoformans phenotype with clinical outcome, MBio, 2, 10.1128/mBio.00217-11

Mottola, 2014, Tropheryma whipplei, the agent of Whipple's disease, affects the early to late phagosome transition and survives in a Rab5- and Rab7-positive compartment, PLoS ONE, 9, e89367, 10.1371/journal.pone.0089367

Nunes, 2010, The role of calcium signaling in phagocytosis, J Leukoc Biol, 88, 57, 10.1189/jlb.0110028

Orsi, 2009, The ABC transporter-encoding gene AFR1 affects the resistance of Cryptococcus neoformans to microglia-mediated antifungal activity by delaying phagosomal maturation, FEMS Yeast Res, 9, 301, 10.1111/j.1567-1364.2008.00470.x

Park, 2009, Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS, AIDS, 23, 525, 10.1097/QAD.0b013e328322ffac

Purdy, 2005, Kinetics of phosphatidylinositol-3-phosphate acquisition differ between IgG bead-containing phagosomes and Mycobacterium tuberculosis-containing phagosomes, Cell Microbiol, 7, 1627, 10.1111/j.1462-5822.2005.00580.x

Qin, 2011, Functional analysis of host factors that mediate the intracellular lifestyle of Cryptococcus neoformans, PLoS Pathog, 7, e1002078, 10.1371/journal.ppat.1002078

Rutherford, 2014, The emerging role of urease as a general microbial virulence factor, PLoS Pathog, 10, e1004062, 10.1371/journal.ppat.1004062

Sabiiti, 2014, Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis, J Clin Invest, 124, 2000, 10.1172/JCI72950

Santangelo, 2004, Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model, Infect Immun, 72, 2229, 10.1128/IAI.72.4.2229-2239.2004

Shao, 2005, An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia, J Immunol, 175, 3244, 10.4049/jimmunol.175.5.3244

Singh, 2013, Factors required for activation of urease as a virulence determinant in Cryptococcus neoformans, MBio, 4, e00220-13, 10.1128/mBio.00220-13

Smith, 2013, Mechanisms of microbial escape from phagocyte killing, Biochem Soc Trans, 41, 475, 10.1042/BST20130014

Strasser, 1999, Regulation of the macrophage vacuolar ATPase and phagosome-lysosome fusion by Histoplasma capsulatum, J Immunol, 162, 6148, 10.4049/jimmunol.162.10.6148

Sun, 2010, Mycobacterial nucleoside diphosphate kinase blocks phagosome maturation in murine RAW 264.7 macrophages, PLoS ONE, 5, e8769, 10.1371/journal.pone.0008769

Tejle, 2002, Phagocytosis and phagosome maturation are regulated by calcium in J774 macrophages interacting with unopsonized prey, Biosci Rep, 22, 529, 10.1023/A:1022025903688

Tucker, 2002, Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm, Proc Natl Acad Sci USA, 99, 3165, 10.1073/pnas.052702799

Vecchiarelli, 1994, Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages, Clin Exp Immunol, 98, 217, 10.1111/j.1365-2249.1994.tb06128.x

Vecchiarelli, 2013, Elucidating the immunological function of the Cryptococcus neoformans capsule, Future Microbiol, 8, 1107, 10.2217/fmb.13.84

Vergne, 2003, Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade, J Exp Med, 198, 653, 10.1084/jem.20030527

Via, 1997, Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7, J Biol Chem, 272, 13326, 10.1074/jbc.272.20.13326

Vylkova, 2014, Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport, PLoS Pathog, 10, e1003995, 10.1371/journal.ppat.1003995