The evidence basis for coenzyme Q therapy in oxidative phosphorylation disease

Mitochondrion - Tập 7 - Trang S136-S145 - 2007
Richard H. Haas1
1Departments of Neurosciences and Pediatrics, UCSD Mitochondrial and Metabolic Disease Center, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0935, USA

Tài liệu tham khảo

Abe, 1999, Effect of coenzyme Q10 in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS): evaluation by noninvasive tissue oximetry, J. Neurol. Sci., 162, 65, 10.1016/S0022-510X(98)00296-2 Artuch, 2006, Cerebellar ataxia with coenzyme Q10 deficiency: diagnosis and follow-up after coenzyme Q10 supplementation, J. Neurol. Sci., 246, 153, 10.1016/j.jns.2006.01.021 Barbiroli, 1997, Coenzyme Q10 improves mitochondrial respiration in patients with mitochondrial cytopathies. An in vivo study on brain and skeletal muscle by phosphorous magnetic resonance spectroscopy, Cell. Mol. Biol. (Noisy-le-grand), 43, 741 Barshop, 2004, Chronic treatment of mitochondrial disease patients with dichloroacetate, Mol. Genet. Metab., 83, 138, 10.1016/j.ymgme.2004.06.009 Beal, 2005, Mitochondria take center stage in aging and neurodegeneration, Ann. Neurol., 58, 495, 10.1002/ana.20624 Bendahan, 1992, 31P NMR spectroscopy and ergometer exercise test as evidence for muscle oxidative performance improvement with coenzyme Q in mitochondrial myopathies, Neurology, 42, 1203, 10.1212/WNL.42.6.1203 Bentinger, 2003, Distribution and breakdown of labeled coenzyme Q10 in rat, Free Radic. Biol. Med., 34, 563, 10.1016/S0891-5849(02)01357-6 Bernier, 2002, Diagnostic criteria for respiratory chain disorders in adults and children, Neurology, 59, 1406, 10.1212/01.WNL.0000033795.17156.00 Boitier, 1998, A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency, J. Neurol. Sci., 156, 41, 10.1016/S0022-510X(98)00006-9 Bresolin, 1988, Clinical and biochemical correlations in mitochondrial myopathies treated with coenzyme Q10, Neurology, 38, 892, 10.1212/WNL.38.6.892 Bresolin, 1990, Ubidecarenone in the treatment of mitochondrial myopathies: a multi-center double-blind trial, J. Neurol. Sci., 100, 70, 10.1016/0022-510X(90)90015-F Brown Melissa, 2005 Chan, 1998, Metabolic changes in patients with mitochondrial myopathies and effects of coenzyme Q10 therapy, J. Neurol., 245, 681, 10.1007/s004150050267 Chen, 1997, Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Short-term double-blind, crossover study, Eur. Neurol., 37, 212, 10.1159/000117445 Chinnery, P., Majamaa, K., Turnbull, D., Thorburn, D., 2006. Treatment for mitochondrial disorders. Cochrane Database Syst. Rev., CD004426. Corral-Debrinski, 1992, Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age, Nat. Genet., 2, 324, 10.1038/ng1292-324 Corral-Debrinski, 1992, Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease, Mutat. Res., 275, 169, 10.1016/0921-8734(92)90021-G Desnuelle, 1989, Kearns–Sayre syndrome: mitochondrial encephalomyopathy caused by deficiency of the respiratory chain, Rev. Neurol. (Paris), 145, 842 Di Giovanni, 2001, Coenzyme Q10 reverses pathological phenotype and reduces apoptosis in familial CoQ10 deficiency, Neurology, 57, 515, 10.1212/WNL.57.3.515 Evidenced Based Medicine Working Group, 1992, Evidence-based medicine. A new approach to teaching the practice of medicine. Evidence-Based Medicine Working Group, JAMA, 268, 2420, 10.1001/jama.1992.03490170092032 Ferrante, 2005, Tolerance of high-dose (3,000mg/day) coenzyme Q10 in ALS, Neurology, 65, 1834, 10.1212/01.wnl.0000187070.35365.d7 Folkers, 1995, Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies, Biochim. Biophys. Acta, 1271, 281, 10.1016/0925-4439(95)00040-B Gold, 1996, Phosphorus magnetic resonance spectroscopy in the evaluation of mitochondrial myopathies: results of a 6-month therapy study with coenzyme Q, Eur. Neurol., 36, 191, 10.1159/000117246 Hart, 2005, Antioxidant treatment of patients with Friedreich ataxia: four-year follow-up, Arch. Neurol., 62, 621, 10.1001/archneur.62.4.621 Huntington’s Study Group, 2001, A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington’s disease, Neurology, 57, 397, 10.1212/WNL.57.3.397 Huntington Study Group (2005) PRE2CARE: A dosage ranging trial of CoEnzymeQ10 in Huntington’s disease and normal subjects. HDF Biennial Symposia. Cambridge, MA. Kamzalov, 2003, Coenzyme Q intake elevates the mitochondrial and tissue levels of Coenzyme Q and alpha-tocopherol in young mice, J. Nutr., 133, 3175, 10.1093/jn/133.10.3175 Kaufmann, 2006, Dichloroacetate causes toxic neuropathy in MELAS: a randomized, controlled clinical trial, Neurology, 66, 324, 10.1212/01.wnl.0000196641.05913.27 Koroshetz, 1997, Energy metabolism defects in Huntington’s disease and effects of coenzyme Q10, Ann. Neurol., 41, 160, 10.1002/ana.410410206 Kwong, 2002, Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat, Free Radic. Biol. Med., 33, 627, 10.1016/S0891-5849(02)00916-4 Lalani, 2005, Isolated mitochondrial myopathy associated with muscle coenzyme Q10 deficiency, Arch. Neurol., 62, 317, 10.1001/archneur.62.2.317 Lamperti, 2005, Muscle coenzyme Q10 level in statin-related myopathy, Arch. Neurol., 62, 1709, 10.1001/archneur.62.11.1709 Lass, 1999, Effects of coenzyme Q10 and alpha-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial alpha-tocopherol by coenzyme Q10, Free Radic. Biol. Med., 26, 1375, 10.1016/S0891-5849(98)00330-X Low, 1992, Effects of mevinolin treatment on tissue dolichol and ubiquinone levels in the rat, Biochim. Biophys. Acta, 1165, 102, 10.1016/0005-2760(92)90081-6 Manzoli, 1990, Coenzyme Q10 in dilated cardiomyopathy, Int. J. Tissue React., 12, 173 Matsuoka, 1991, Muscle coenzyme Q10 in mitochondrial encephalomyopathies, Neuromuscul. Disord., 1, 443, 10.1016/0960-8966(91)90007-F Matthews, 1993, Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease, Neurology, 43, 884, 10.1212/WNL.43.5.884 Mckenzie, 2004, Mitochondrial disease: mutations and mechanisms, Neurochem. Res., 29, 589, 10.1023/B:NERE.0000014829.42364.dd Mecocci, 1993, Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain, Ann. Neurol., 34, 609, 10.1002/ana.410340416 Miles, 2005, Muscle coenzyme Q: a potential test for mitochondrial activity and redox status, Pediatr. Neurol., 32, 318, 10.1016/j.pediatrneurol.2005.01.009 Montero, 2005, Muscle coenzyme Q10 concentrations in patients with probable and definite diagnosis of respiratory chain disorders, Biofactors, 25, 109, 10.1002/biof.5520250112 Muller, 1990, Coenzyme Q in opthalmoplegia plus – a double blind, cross over therapeutic trial, J. Neurol. Sci., 98, 442 Musumeci, 2001, Familial cerebellar ataxia with muscle coenzyme Q10 deficiency, Neurology, 56, 849, 10.1212/WNL.56.7.849 Ogasahara, 1989, Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy, Proc. Natl. Acad. Sci. USA, 86, 2379, 10.1073/pnas.86.7.2379 Ogasahara, 1986, Treatment of Kearns–Sayre syndrome with coenzyme Q10, Neurology, 36, 45, 10.1212/WNL.36.1.45 Pepe, S., Marasco, S.F., Haas, S.J., F.L., S., H., K., & Rosenfeldt, F. (2007) Coenzyme Q10 in Cardiovascular Disease. Mitochondrion, in press. Peterson, 1995, The treatment of mitochondrial myopathies and encephalomyopathies, Biochim. Biophys. Acta, 1271, 275, 10.1016/0925-4439(95)00039-7 Quiles, 2005, Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage, Biofactors, 25, 73, 10.1002/biof.5520250109 Quinzii, 2007, Human coenzyme Q(10) deficiency, Neurochem. Res., 32, 723, 10.1007/s11064-006-9190-z Quinzii, 2005, Coenzyme Q deficiency and cerebellar ataxia associated with an aprataxin mutation, Neurology, 64, 539, 10.1212/01.WNL.0000150588.75281.58 Rebrin, 2004, Tissue bioavailability and detection of coenzyme Q, Methods Enzymol., 378, 138, 10.1016/S0076-6879(04)78009-X Rodriguez, 2007, Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders, Muscle Nerve, 35, 235, 10.1002/mus.20688 Rosenfeldt, 2005, Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue, J. Thorac. Cardiovasc. Surg., 129, 25, 10.1016/j.jtcvs.2004.03.034 Rotig, 2000, Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency, Lancet, 356, 391, 10.1016/S0140-6736(00)02531-9 Rundek, 2004, Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke, Arch. Neurol., 61, 889, 10.1001/archneur.61.6.889 Sackett, 1993, Rules of evidence and clinical recommendations for the management of patients, Can. J. Cardiol., 9, 487 Salviati, 2005, Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition, Neurology, 65, 606, 10.1212/01.wnl.0000172859.55579.a7 Sander, 2006, The impact of coenzyme Q10 on systolic function in patients with chronic heart failure, J. Card. Fail., 12, 464, 10.1016/j.cardfail.2006.03.007 Sanderson, 2006, The incidence of inherited metabolic disorders in the West Midlands, UK, Arch. Dis. Child, 91, 896, 10.1136/adc.2005.091637 Scalori, 1990, Plasma and tissue concentrations of coenzyme Q10 in the rat after intravenous, oral and topical administrations, Int. J. Tissue React., 12, 149 Schapira, 2006, Mitochondrial disease, Lancet, 368, 70, 10.1016/S0140-6736(06)68970-8 Shults, 2004, Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson’s disease, Exp. Neurol., 188, 491, 10.1016/j.expneurol.2004.05.003 Shults, 2005, Clinical trials of coenzyme Q10 in neurological disorders, Biofactors, 25, 117, 10.1002/biof.5520250113 Shults, 2002, Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline, Arch. Neurol., 59, 1541, 10.1001/archneur.59.10.1541 Skladal, 2003, Minimum birth prevalence of mitochondrial respiratory chain disorders in children, Brain, 126, 1905, 10.1093/brain/awg170 Suzuki, 1998, The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation, Diabetologia, 41, 584, 10.1007/s001250050950 Vissing, 2001, Exercise intolerance in mitochondrial myopathy is not related to lactic acidosis, Ann. Neurol., 49, 672, 10.1002/ana.1026 Wallace, 1995, Mitochondrial DNA mutations in human degenerative diseases and aging, Biochim. Biophys. Acta, 1271, 141, 10.1016/0925-4439(95)00021-U Wei, 2001, Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system, Chin. J. Physiol., 44, 1 Yuzuriha, 1983, Transport of [14C]coenzyme Q10 from the liver to other tissues after intravenous administration to guinea pigs, Biochim. Biophys. Acta, 759, 286, 10.1016/0304-4165(83)90325-2 Zhang, 1995, Uptake of dietary coenzyme Q supplement is limited in rats, J. Nutr., 125, 446 Zierz, 1989, Coenzyme Q in serum and muscle of 5 patients with Kearns–Sayre syndrome and 12 patients with ophthalmoplegia plus, J. Neurol., 236, 97, 10.1007/BF00314404