The emerging role of long non-coding RNAs in endometrial cancer

Cancer Genetics - Tập 209 - Trang 445-455 - 2016
Konii Takenaka1, Bei Jun Chen1, Susan C. Modesitt2, Frances L. Byrne1, Kyle L. Hoehn1, Michael Janitz1
1School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia
2Division of Gynecologic Oncology, Obstetrics and Gynecology Department, University of Virginia Health System, Charlottesville, VA 22908, USA

Tài liệu tham khảo

Siegel, 2016, Cancer statistics, 2016, CA Cancer J Clin, 66, 7, 10.3322/caac.21332 Ferlay, 2015, Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012, Int J Cancer, 136, E359, 10.1002/ijc.29210 Karageorgi, 2010, Reproductive factors and postmenopausal hormone use in relation to endometrial cancer risk in the Nurses' Health Study cohort 1976–2004, Int J Cancer, 126, 208, 10.1002/ijc.24672 Renehan, 2008, Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies, Lancet, 371, 569, 10.1016/S0140-6736(08)60269-X Grady, 1995, Hormone replacement therapy and endometrial cancer risk: a meta-analysis, Obstet Gynecol, 85, 304, 10.1016/0029-7844(94)00383-O Friberg, 2007, Diabetes and risk of endometrial cancer: a population-based prospective cohort study, Cancer Epidemiol Biomarkers Prev, 16, 276, 10.1158/1055-9965.EPI-06-0751 Yang, 2015, Infertility and incident endometrial cancer risk: a pooled analysis from the epidemiology of endometrial cancer consortium (E2C2), Br J Cancer, 112, 925, 10.1038/bjc.2015.24 Doll, 2008, Novel molecular profiles of endometrial cancer—new light through old windows, J Steroid Biochem Mol Biol, 108, 221, 10.1016/j.jsbmb.2007.09.020 Bokhman, 1983, Two pathogenetic types of endometrial carcinoma, Gynecol Oncol, 15, 10, 10.1016/0090-8258(83)90111-7 Sherman, 2000, Theories of endometrial carcinogenesis: a multidisciplinary approach, Mod Pathol, 13, 295, 10.1038/modpathol.3880051 Srijaipracharoen, 2010, Expression of ER, PR, and Her-2/neu in endometrial cancer: a clinicopathological study, Asian Pac J Cancer Prev, 11, 215 Fukuda, 1998, Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma, Gynecol Oncol, 69, 220, 10.1006/gyno.1998.5023 Zhang, 2015, Prognostic role of hormone receptors in endometrial cancer: a systematic review and meta-analysis, World J Surg Oncol, 13, 208, 10.1186/s12957-015-0619-1 Cheung, 2011, High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability, Cancer Discov, 1, 170, 10.1158/2159-8290.CD-11-0039 Djordjevic, 2012, Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing, Mod Pathol, 25, 699, 10.1038/modpathol.2011.208 Byron, 2012, FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features, PLoS ONE, 7, 10.1371/annotation/0bfaecca-0f87-43fe-97cc-f2ae3ddeb6d5 Fukuchi, 1998, Beta-catenin mutation in carcinoma of the uterine endometrium, Cancer Res, 58, 3526 Llauradó, 2012, Molecular bases of endometrial cancer: new roles for new actors in the diagnosis and the therapy of the disease, Mol Cell Endocrinol, 358, 244, 10.1016/j.mce.2011.10.003 Mutter, 2000, Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers, J Natl Cancer Inst, 92, 924, 10.1093/jnci/92.11.924 Kandoth, 2013, Integrated genomic characterization of endometrial carcinoma, Nature, 497, 67, 10.1038/nature12113 Boruta, 2009, Management of women with uterine papillary serous cancer: a Society of Gynecologic Oncology (SGO) review, Gynecol Oncol, 115, 142, 10.1016/j.ygyno.2009.06.011 Mendivil, 2009, Non-endometrioid adenocarcinoma of the uterine corpus: a review of selected histological subtypes, Cancer Control, 16, 46, 10.1177/107327480901600107 Olawaiye, 2009, Management of women with clear cell endometrial cancer: a Society of Gynecologic Oncology (SGO) review, Gynecol Oncol, 113, 277, 10.1016/j.ygyno.2009.02.003 Rose, 1996, Endometrial carcinoma, N Engl J Med, 335, 640, 10.1056/NEJM199608293350907 Lax, 2000, The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways, Cancer, 88, 814, 10.1002/(SICI)1097-0142(20000215)88:4<814::AID-CNCR12>3.0.CO;2-U Lax, 2004, Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification, Virchows Arch, 444, 213, 10.1007/s00428-003-0947-3 Santin, 2005, Determination of HER2/neu status in uterine serous papillary carcinoma: comparative analysis of immunohistochemistry and fluorescence in situ hybridization, Gynecol Oncol, 98, 24, 10.1016/j.ygyno.2005.03.041 Bansal, 2009, The molecular biology of endometrial cancers and the implications for pathogenesis, classification, and targeted therapies, Cancer Control, 16, 8, 10.1177/107327480901600102 Salvesen, 2005, Low frequency of BRAF and CDKN2A mutations in endometrial cancer, Int J Cancer, 115, 930, 10.1002/ijc.20702 Yalta, 2009, E-cadherin expression in endometrial malignancies: comparison between endometrioid and non-endometrioid carcinomas, J Int Med Res, 37, 163, 10.1177/147323000903700119 Llobet, 2009, Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints, J Clin Pathol, 62, 777, 10.1136/jcp.2008.056101 Creasman, 2009, Revised FIGO staging for carcinoma of the endometrium, Int J Gynaecol Obstet, 105, 109, 10.1016/j.ijgo.2009.02.010 Pecorelli, 2009, Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium, Int J Gynaecol Obstet, 105, 103, 10.1016/j.ijgo.2009.02.012 Benedet, 2000, FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology, Int J Gynaecol Obstet, 70, 209, 10.1016/S0020-7292(00)90001-8 Creasman, 2006, Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer, Int J Gynaecol Obstet, 95, S105, 10.1016/S0020-7292(06)60031-3 Sorosky, 2012, Endometrial cancer, Obstet Gynecol, 120, 383, 10.1097/AOG.0b013e3182605bf1 Colombo, 2013, Endometrial cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up, Ann Oncol, 24, vi33, 10.1093/annonc/mdt353 Djebali, 2012, Landscape of transcription in human cells, Nature, 489, 101, 10.1038/nature11233 Carninci, 2005, The transcriptional landscape of the mammalian genome, Science, 309, 1559, 10.1126/science.1112014 Szymanski, 2005, A new frontier for molecular medicine: noncoding RNAs, Biochim Biophys Acta, 1756, 65 Zhao, 2014, Comparison of RNA-seq and microarray in transcriptome profiling of activated T cells, PLoS ONE, 9, 10.1371/journal.pone.0078644 Ramaswami, 2013, Identifying RNA editing sites using RNA sequencing data alone, Nat Methods, 10, 128, 10.1038/nmeth.2330 Wang, 2009, RNA-seq: a revolutionary tool for transcriptomics, Nat Rev Genet, 10, 57, 10.1038/nrg2484 Mills, 2012, Alternative splicing of mRNA in the molecular pathology of neurodegenerative diseases, Neurobiol Aging, 33, 1012, 10.1016/j.neurobiolaging.2011.10.030 Yandell, 2012, A beginner's guide to eukaryotic genome annotation, Nat Rev Genet, 13, 329, 10.1038/nrg3174 Trapnell, 2012, Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks, Nat Protocols, 7, 562, 10.1038/nprot.2012.016 Kapranov, 2007, RNA maps reveal new RNA classes and a possible function for pervasive transcription, Science, 316, 1484, 10.1126/science.1138341 Ravasi, 2006, Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome, Genome Res, 16, 11, 10.1101/gr.4200206 Cabili, 2011, Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses, Genes Dev, 25, 1915, 10.1101/gad.17446611 Mercer, 2009, Long non-coding RNAs: insights into functions, Nat Rev Genet, 10, 155, 10.1038/nrg2521 Harrow, 2012, GENCODE: the reference human genome annotation for The ENCODE Project, Genome Res, 22, 1760, 10.1101/gr.135350.111 Hrdlickova, 2014, Genetic variation in the non-coding genome: involvement of micro-RNAs and long non-coding RNAs in disease, Biochi Biophys Acta, 1842, 1910, 10.1016/j.bbadis.2014.03.011 Wang, 2011, Molecular mechanisms of long noncoding RNAs, Mol Cell, 43, 904, 10.1016/j.molcel.2011.08.018 Loewer, 2010, Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells, Nat Genet, 42, 1113, 10.1038/ng.710 Huang, 2014, Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1), Cell Death Dis, 5, e1008, 10.1038/cddis.2013.541 Wang, 2008, UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion, FEBS Lett, 582, 1919, 10.1016/j.febslet.2008.05.012 Kotake, 2011, Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene, Oncogene, 30, 10.1038/onc.2010.568 Kloosterman, 2006, The diverse functions of MicroRNAs in animal development and disease, Dev Cell, 11, 441, 10.1016/j.devcel.2006.09.009 Filipowicz, 2008, Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?, Nat Rev Genet, 9, 102, 10.1038/nrg2290 Eulalio, 2008, Getting to the root of miRNA-mediated gene silencing, Cell, 132, 9, 10.1016/j.cell.2007.12.024 Salmena, 2011, A ceRNA hypothesis: the Rosetta stone of a hidden RNA language?, Cell, 146, 353, 10.1016/j.cell.2011.07.014 Bartel, 2009, MicroRNAs: target recognition and regulatory functions, Cell, 136, 215, 10.1016/j.cell.2009.01.002 Poliseno, 2010, A coding-independent function of gene and pseudogene mRNAs regulates tumour biology, Nature, 465, 1033, 10.1038/nature09144 Balakirev, 2003, Pseudogenes: are they “junk” or functional DNA?, Annu Rev Genet, 37, 123, 10.1146/annurev.genet.37.040103.103949 Mighell, 2000, Vertebrate pseudogenes, FEBS Lett, 468, 109, 10.1016/S0014-5793(00)01199-6 Echols, 2002, Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes, Nucleic Acids Res, 30, 2515, 10.1093/nar/30.11.2515 Huang, 2016, The long noncoding RNA CASC2 functions as a competing endogenous RNA by sponging miR-18a in colorectal cancer, Sci Rep, 6, 26524, 10.1038/srep26524 Chen, 2016, Characterization of circular RNAs landscape in multiple system atrophy brain, J Neurochem, 10.1111/jnc.13752 Li, 2015, Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway, Oncotarget, 6, 6001, 10.18632/oncotarget.3469 Huang, 2015, cir-ITCH Plays an inhibitory role in colorectal cancer by regulating the Wnt/β-catenin pathway, PLoS ONE, 10 Amaral, 2011, lncRNAdb: a reference database for long noncoding RNAs, Nucleic Acids Res, 39, D146, 10.1093/nar/gkq1138 Luk, 2015, GermlncRNA: a unique catalogue of long non-coding RNAs and associated regulations in male germ cell development, Database (Oxford), 2015, bav044, 10.1093/database/bav044 Quek, 2015, lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs, Nucleic Acids Res, 43, D168, 10.1093/nar/gku988 Volders, 2013, LNCipedia: a database for annotated human lncRNA transcript sequences and structures, Nucleic Acids Res, 41, D246, 10.1093/nar/gks915 Fritah, 2014, Databases for lncRNAs: a comparative evaluation of emerging tools, RNA, 20, 1655, 10.1261/rna.044040.113 Guffanti, 2009, A transcriptional sketch of a primary human breast cancer by 454 deep sequencing, BMC Genomics, 10, 163, 10.1186/1471-2164-10-163 Ren, 2013, Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer, J Urol, 190, 2278, 10.1016/j.juro.2013.07.001 Lai, 2012, Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation, Med Oncol, 29, 1810, 10.1007/s12032-011-0004-z Guo, 2010, Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion, Acta Biochim Biophys Sin (Shanghai), 42, 224, 10.1093/abbs/gmq008 Zhao, 2014, A novel wnt regulatory axis in endometrioid endometrial cancer, Cancer Res, 74, 5103, 10.1158/0008-5472.CAN-14-0427 Hajjari, 2015, HOTAIR: an oncogenic long non-coding RNA in different cancers, Cancer Biol Med, 12, 1 He, 2014, The long non-coding RNA HOTAIR is upregulated in endometrial carcinoma and correlates with poor prognosis, Int J Mol Med, 33, 325, 10.3892/ijmm.2013.1570 Huang, 2014, Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancer, Arch Gynecol Obstet, 290, 717, 10.1007/s00404-014-3236-2 Gupta, 2010, Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis, Nature, 464, 1071, 10.1038/nature08975 Kogo, 2011, Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers, Cancer Res, 71, 6320, 10.1158/0008-5472.CAN-11-1021 Lanz, 1999, A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex, Cell, 97, 17, 10.1016/S0092-8674(00)80711-4 Lanz, 2003, Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo, Mol Cell Biol, 23, 7163, 10.1128/MCB.23.20.7163-7176.2003 Akrami, 2013, Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification, PLoS ONE, 8, 10.1371/journal.pone.0080306 Gabory, 2010, The H19 locus: role of an imprinted non-coding RNA in growth and development, Bioessays, 32, 473, 10.1002/bies.200900170 Zemel, 1992, Physical linkage of two mammalian imprinted genes, H19 and insulin-like growth factor 2, Nat Genet, 2, 61, 10.1038/ng0992-61 Cui, 2002, Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2, Cancer Res, 62, 6442 Verkerk, 1997, Unique expression patterns of H19 in human testicular cancers of different etiology, Oncogene, 14, 95, 10.1038/sj.onc.1200802 Dugimont, 1995, The H19 gene is expressed within both epithelial and stromal components of human invasive adenocarcinomas, Biol Cell, 85, 117, 10.1016/0248-4900(96)85272-5 Tanos, 1999, Expression of the imprinted H19 oncofetal RNA in epithelial ovarian cancer, Eur J Obstet Gynecol Reprod Biol, 85, 7, 10.1016/S0301-2115(98)00275-9 Tanos, 2004, H19 and IGF2 gene expression in human normal, hyperplastic, and malignant endometrium, Int J Gynecol Cancer, 14, 521, 10.1111/j.1048-891x.2004.014314.x Ratajczak, 2012, Igf2-H19, an imprinted tandem Yin-Yanggene and its emerging role in development, proliferation of pluripotent stem cells, senescence and cancerogenesis, J Stem Cell Res Ther, 2, 108, 10.4172/2157-7633.1000e108 Yan, 2015, Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation, Oncogene, 34, 3076, 10.1038/onc.2014.236 Tsang, 2010, Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer, Carcinogenesis, 31, 350, 10.1093/carcin/bgp181 Xin, 2015, Long non-coding RNA derived miR-205-5p modulates human endometrial cancer by targeting PTEN, Am J Transl Res, 7, 2433 Baldinu, 2004, Identification of a novel candidate gene, CASC2, in a region of common allelic loss at chromosome 10q26 in human endometrial cancer, Hum Mutat, 23, 318, 10.1002/humu.20015 Baldinu, 2007, CASC2a gene is down-regulated in endometrial cancer, Anticancer Res, 27, 235 Peiffer, 1995, Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers, Cancer Res, 55, 1922 Sonoda, 1997, Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization, Genes Chromosomes Cancer, 18, 115, 10.1002/(SICI)1098-2264(199702)18:2<115::AID-GCC6>3.0.CO;2-5 Wang, 2015, Long non-coding RNA CASC2 suppresses malignancy in human gliomas by miR-21, Cell Signal, 27, 275, 10.1016/j.cellsig.2014.11.011 He, 2016, Low expression of long noncoding RNA CASC2 indicates a poor prognosis and regulates cell proliferation in non-small cell lung cancer, Tumor Biol, 9503, 10.1007/s13277-016-4787-6 Zhai, 2015, Microarray expression profile of lncRNAs and the upregulated ASLNC04080 lncRNA in human endometrial carcinoma, Int J Oncol, 46, 2125, 10.3892/ijo.2015.2897 Yang, 2015, Expression profile of long non-coding RNAs is altered in endometrial cancer, Int J Clin Exp Med, 8, 5010 You, 2015, Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity, Nat Neurosci, 18, 603, 10.1038/nn.3975 Li, 2015, Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis, Cell Res, 25, 981, 10.1038/cr.2015.82 Bachmayr-Heyda, 2015, Correlation of circular RNA abundance with proliferation—exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues, Sci Rep, 5, 8057, 10.1038/srep08057