The emerging landscape of circular RNA ciRS-7 in cancer (Review)

Ferlay, 2015, Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012, Int J Cancer, 136, E359, 10.1002/ijc.29210

Dušek, 2014, Epidemiology of screening-targeted cancers according to new data of the Czech National Cancer Registry, Klin Onkol, 27, 19, 10.14735/amko20142S19

Rosenberg, 2014, Insurance status and risk of cancer mortality among adolescents and young adults, Cancer

Zhang, 2014, MicroRNA-7 arrests cell cycle in G1 phase by directly targeting CCNE1 in human hepatocellular carcinoma cells, Biochem Biophys Res Commun, 443, 1078, 10.1016/j.bbrc.2013.12.095

Bartel, 2004, MicroRNAs: Genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5

Zhang, 2014, MiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway, Stem Cells, 32, 2858, 10.1002/stem.1795

Jiang, 2010, MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells, Biochem J, 432, 199, 10.1042/BJ20100859

Kong, 2012, Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells, Oncogene, 31, 3949, 10.1038/onc.2011.558

Li, 2014, Restoration of miR-7 expression suppresses the growth of Lewis lung cancer cells by modulating epidermal growth factor receptor signaling, Oncol Rep, 32, 2511, 10.3892/or.2014.3519

Fang, 2012, MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma, Hepatology, 55, 1852, 10.1002/hep.25576

Saydam, 2011, miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways, Cancer Res, 71, 852, 10.1158/0008-5472.CAN-10-1219

Liu, 2013, MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells, FEBS Lett, 587, 2247, 10.1016/j.febslet.2013.05.054

Hansen, 2013, Natural RNA circles function as efficient microRNA sponges, Nature, 495, 384, 10.1038/nature11993

Memczak, 2013, Circular RNAs are a large class of animal RNAs with regulatory potency, Nature, 495, 333, 10.1038/nature11928

Salzman, 2012, Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types, PLoS One, 7, e30733, 10.1371/journal.pone.0030733

Hansen, 2011, miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA, EMBO J, 30, 4414, 10.1038/emboj.2011.359

Salmena, 2011, A ceRNA hypothesis: The Rosetta Stone of a hidden RNA language?, Cell, 146, 353, 10.1016/j.cell.2011.07.014

Hsu, 1979, Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells, Nature, 280, 339, 10.1038/280339a0

Cocquerelle, 1993, Mis-splicing yields circular RNA molecules, FASEB J, 7, 155, 10.1096/fasebj.7.1.7678559

Jeck, 2013, Circular RNAs are abundant, conserved, and associated with ALU repeats, RNA, 19, 141, 10.1261/rna.035667.112

Jeck, 2014, Detecting and characterizing circular RNAs, Nat Biotechnol, 32, 453, 10.1038/nbt.2890

Zhang, 2014, Complementary sequence-mediated exon circularization, Cell, 159, 134, 10.1016/j.cell.2014.09.001

Vicens, 2014, Biogenesis of Circular RNAs, Cell, 159, 13, 10.1016/j.cell.2014.09.005

Liang, 2014, Short intronic repeat sequences facilitate circular RNA production, Genes Dev, 28, 2233, 10.1101/gad.251926.114

Danan, 2012, Transcriptome-wide discovery of circular RNAs in Archaea, Nucleic Acids Res, 40, 3131, 10.1093/nar/gkr1009

Wilusz, 2013, Molecular biology. A circuitous route to noncoding RNA, Science, 340, 440, 10.1126/science.1238522

Guo, 2014, Expanded identification and characterization of mammalian circular RNAs, Genome Biol, 15, 409, 10.1186/s13059-014-0409-z

Wang, 2014, Circular RNA is expressed across the eukaryotic tree of life, PLoS One, 9, e90859, 10.1371/journal.pone.0090859

Ghosal, 2013, Circ2Traits: A comprehensive database for circular RNA potentially associated with disease and traits, Front Genet, 4, 283, 10.3389/fgene.2013.00283

Chen, 1995, Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs, Science, 268, 415, 10.1126/science.7536344

Kato, 2012, Cell-free formation of RNA granules: Low complexity sequence domains form dynamic fibers within hydrogels, Cell, 149, 753, 10.1016/j.cell.2012.04.017

Ledford, 2013, Circular RNAs throw genetics for a loop, Nature, 494, 415, 10.1038/494415a

Maqbool, 2014, Mutations in microRNA genes and their binding sites are infrequently associated with human colorectal cancer in the Kashmiri population, MicroRNA, 2, 219, 10.2174/2211536602666140102001007

Macha, 2014, MicroRNAs (miRNAs) as biomarker(s) for prognosis and diagnosis of gastrointestinal (GI) cancers, Curr Pharm Des, 20, 5287, 10.2174/1381612820666140128213117

Calin, 2004, Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers, Proc Natl Acad Sci USA, 101, 2999, 10.1073/pnas.0307323101

Di Leva, 2014, MicroRNAs in cancer, Annu Rev Pathol, 9, 287, 10.1146/annurev-pathol-012513-104715

Yao, 2010, MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma, Hepatology, 51, 846

Ma, 2013, Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cells, IUBMB Life, 65, 1026, 10.1002/iub.1231

Stock, 2014, Induction of pancreatic cancer cell migration by an autocrine epidermal growth factor receptor activation, Exp Cell Res, 326, 307, 10.1016/j.yexcr.2014.04.022

Ribeiro, 2014, Effective targeting of the epidermal growth factor receptor (EGFR) for treating oral cancer: A promising approach, Anticancer Res, 34, 1547

Tomao, 2014, Cervical cancer: Are there potential new targets? An update on preclinical and clinical results, Curr Drug Targets, 15, 1107, 10.2174/1389450115666141010145547

Ma, 2013, Genetic variations in EGFR and ERBB4 increase susceptibility to cervical cancer, Gynecol Oncol, 131, 445, 10.1016/j.ygyno.2013.07.113

Nogueira-Rodrigues, 2014, Phase 2 trial of erlotinib combined with cisplatin and radiotherapy in patients with locally advanced cervical cancer, Cancer, 120, 1187, 10.1002/cncr.28471

Van Themsche, 2010, XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling, Mol Cancer, 9, 216, 10.1186/1476-4598-9-216

Gagnon, 2008, Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol, Apoptosis, 13, 259, 10.1007/s10495-007-0165-6

Yang, 2014, Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis, PLoS One, 9, e88827, 10.1371/journal.pone.0088827

Yang, 2012, Krüppel-like factor 4 functions as a tumor suppressor in cervical carcinoma, Cancer, 118, 3691, 10.1002/cncr.26698

Burd, 2010, Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk, PLoS Genet, 6, e1001233, 10.1371/journal.pgen.1001233

Lukiw, 2013, Circular RNA (circRNA) in Alzheimer’s disease (AD), Front Genet, 4, 307, 10.3389/fgene.2013.00307

Hansen, 2013, Circular RNA and miR-7 in cancer, Cancer Res, 73, 5609, 10.1158/0008-5472.CAN-13-1568

Kosik, 2013, Molecular biology: Circles reshape the RNA world, Nature, 495, 322, 10.1038/nature11956

AbouHaidar, 2014, Novel coding, translation, and gene expression of a replicating covalently closed circular RNA of 220 nt, Proc Natl Acad Sci USA, 111, 14542, 10.1073/pnas.1402814111

Ashwal-Fluss, 2014, circRNA biogenesis competes with pre-mRNA splicing, Mol Cell, 56, 55, 10.1016/j.molcel.2014.08.019

Perkel, 2013, Assume nothing: The tale of circular RNA, Biotechniques, 55, 55, 10.2144/000114061