The effects of fresh garlic on the serum concentration of total cholesterol, total triglyceride and adipose tissues of broilers

Comparative Clinical Pathology - Tập 19 - Trang 363-365 - 2009
Saied Habibian Dehkordi1, Abdolkarim Zamani Moghadam2, Negahdar Maghsoudi1,2, Ehsan Aali1, Razieh Gerami1, Ehsan Dehsadeghi1
1Division of Pharmacology, Department of Basic Science, University of Shahrekord, Shahrekord, Iran
2Department of Clinical Science, School of Veterinary Medicine, University of Shahrekord, Shahrekord, Iran

Tóm tắt

The aim of this study was to investigate the effects of garlic on total cholesterol, total triglyceride and adipose tissues in chickens, since garlic is typically used as a dietary supplement in broilers' diets. One hundred male broiler chicks were divided randomly into two groups. From the day after they were born, group one received standard feed plus 20 kg/ton dried fresh garlic and group two received just standard feed without added garlic. On day 50, the chickens were individually weighed and slaughtered. Carcasses and adipose tissues were weighed out separately. During the slaughtering process, blood samples were collected to provide serum samples. The sera were used to measure total cholesterol and total triglyceride using routine laboratory methods. All samples were analysed and the results assessed statistically using the t test method. The results showed no significant changes in chicken weights or in chicken carcass weights. However, the results indicated significant decreases in total cholesterol, total triglyceride and adipose tissue, in Group 1 compared with Group 2 (p < 0.001). The results suggest that fresh garlic may reduce total cholesterol, total triglyceride and the amount of carcass adipose tissue in chickens.

Tài liệu tham khảo

Amagase HB, Petesch L, Matsuura H, Kasuga S, Itakura Y (2001) Intake of garlic and its bioactive components. J Nutr 131:955–962 Berthold HK, Sudhop T, Von Bergmann K (1998) Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism: a randomized controlled trial. JAMA 279(23):1900–1902 Burr ML, Fehily AM, Gilbert JF (1989) Effects of changes in fat, fish and fibre intakes on myocardial reinfarction: diet and reinfarction (DART). Lancet 30(2):757–761 Holzgartner H, Schmidt U, Kuhn U (1992) Comparison of the efficacy and tolerance of a garlic preparation vs. bezafibrate. Arzneimittelforschung 42:1473–1477 Isaacsohn JL, Moser M, Stein EA (1998) Garlic powder and plasma lipids and lipoproteins: a multicenter, randomized, placebo-controlled trial. Archive of Internal Medicine 158:1189–1194 Kaul PL, Prasad MC (1990) Hypocholesterolemic and antiatherosclerotic effects of garlic in goats-an experimental study. Indian Vet J 67:1112–1115 Koch HP, Lawson LD (1996) Garlic: the science and therapeutic application of Allium sativum L. and related species, 2nd edn. Williams and Wilkins, Baltimore, pp 10–90 Konjufca VH, Pesti GM, Bakalli RI (1997) Modulation of cholesterol levels in broiler meat by dietary garlic and copper. Poult Sci 76(9):1264–1271 Lau B, Lam F, Wary-Cheng R (1987) Effect of an odor-modified garlic preparation on blood lipids. Nutr Res 7(2):139–149 Murray MT (1995) The healing power of herbs: the enlightened person's guide to the wonders of medicinal plants, 2nd edn. Rocklin, California, pp 30–38 Qureshi AA, Abuirmeileh N, Din ZZ, Elson CE, Burger WC (1983a) Inhibition of cholesterol and fatty acid biosynthesis in liver enzymes and chicken hepatocytes by polar fraction of garlic. Lipids 18(5):343–348 Qureshi AA, Din ZZ, Abuirmeileh N, Burger WC, Ahmad Y, Elson CE (1983b) Suppression of avian hepatic lipid metabolism by solvent extracts of garlic: impact on serum lipids. J Nutr 113:1746–1755 Rifai N, Bachorik PS, Albers JJ (1999) Lipids, lipoproteins and apolipoproteins. In: Burtis CA, Ashwood ER (eds) Tietz textbook of clinical chemistry, 3rd edn. Saunders, Philadelphia, pp 809–861 Silagy CA, Neil HA (1994) A meta-analysis of the effect of garlic on blood pressure. J Hypertens 12:463–468 Simons LA, Balasubramaniam S, Von Konigsmark M, Parfitt A, Simons J, Peters W (1995) The effect of garlic on plasma lipids and lipoproteins in mild hypercholesterolemia. Atherosclerosis 113:219–225 Sklan D, Berner RS, Rabinowitch HD (1992) The effect of dietary onion and garlic on hepatic lipid concentrations and activity of antioxidative enzymes in chicks. J Nutr Biochem 3:322–325