The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1H

Aeed, 1992, Characterisation of the oligosaccharide structures on recombinant human prorenin expressed in chinese Hamster Ovary Cells, Biochemistry, 31, 6951, 10.1021/bi00145a013

Blomberg, 1986, Europium-labelled target cells in an assay of natural killer cell activity, J. Immun., 86, 225

Dorai, 1991, Role of inter-heavy and light chain disulphide bonds in the effector functions of human immunoglobulin IgG1, Molec. Immun., 29, 1487, 10.1016/0161-5890(92)90222-J

Dyer, 1990, Remission induction in patients with lymphoid malignancies using unconjugated Campath-1H monoclonal antibodies, Leuk. Lymph., 2, 179, 10.3109/10428199009053522

Galili, 1987, Evolutionary relationship between the natural anti-Bal antibody and the Gala1-3Gal epitope in primates, 84, 1369

Heyman, 1985, Carbohydrate chains on IgG2b: a requirement for efficient feedback immunosuppression, J. Immun., 134, 4018, 10.4049/jimmunol.134.6.4018

Koide, 1977, Recognition of IgG by Fc receptor and complement: effects of glycosidase digestion, Biochem. biophys. Res. Commun., 75, 838, 10.1016/0006-291X(77)91458-9

Krotkiewski, 1990, The carbohydrate structures of a mouse monoclonal IgG antibody OKT3, J. Biol. Chem., 265, 20195, 10.1016/S0021-9258(17)30489-1

Leatherbarrow, 1985, Effector functions of a monoclonal aglycosylated mouse IgG2a: binding and activation of complement component C1 and interaction with human monocyte Fc receptor, Molec. Immun., 22, 407, 10.1016/0161-5890(85)90125-7

Lines, 1995, High performance liquid chromatographic mapping of the oligosaccharides released from the human immunoglobulin Campath-1H, J. pharm. biomed. Anal.

Lund, 1990, A protein structural change in aglycosylated IgG3 correlates with the loss of huFc gamma R1 and huFc gamma R111 binding and/or activation, Molec. Immun., 27, 1145, 10.1016/0161-5890(90)90103-7

Matsuda, 1990, Proton nuclear magnetic resonance studies of the structure of the Fc fragment of human immunoglobulin G1: comparisons of native and recombinant proteins, Molec. Immun., 27, 571, 10.1016/0161-5890(90)90076-C

Mizuochi, 1982, Structural and numerical variations of the carbohydrate moiety of immunoglobulin G, J. Immun., 129, 2016, 10.4049/jimmunol.129.5.2016

Nose, 1983, Biological significance of carbohydrate chains on monoclonal antibodies, 80, 6632

Nishiura, 1990, Carbohydrate analysis of immunoglobulin myeloma proteins by lectin and high performance liquid chromatography: role of glycosyltransferases in the structures, Cancer Res., 50, 5345

Parekh, 1985, Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG, Nature, 316, 452, 10.1038/316452a0

Pound, 1993, Aglycosylated chimeric human IgG3 can trigger the human phagocyte respiratory burst, Molec. Immun., 30, 233, 10.1016/0161-5890(93)90052-D

Rademacher, 1988, Glycobiology, A. Rev. Biochem., 57, 785, 10.1146/annurev.bi.57.070188.004033

Rothman, 1989, Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation, Molec. Immun., 26, 1113, 10.1016/0161-5890(89)90055-2

Tandai, 1991, Structural study of the sugar moieties of monoclonal antibodies secreted by human-mouse hybridoma, Arch. Biochem. Biophys., 291, 339, 10.1016/0003-9861(91)90144-8

Tao, 1989, Studies of aglycosylated chimeric mouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region, J. Immun., 143, 2595, 10.4049/jimmunol.143.8.2595

Williams, 1973, Studies of biologic and serologic activity of rabbit-IgG antibody depleted of carbohydrate residues, J. Immun., 111, 1690, 10.4049/jimmunol.111.6.1690