The effect of powder type, free moisture and deformation behaviour of granules on the kinetics of fluid-bed granulation

Thomas Abberger1
1Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria

Tài liệu tham khảo

Talu, 2000, Computer simulation of wet granulation, Powder Technol., 110, 59, 10.1016/S0032-5910(99)00268-5 von Smoluchowski, 1918, Versuch einer mathematischen Theorie der Koagulationskinetik kolloider Lösungen, Z. Phys. Chem., 92, 129, 10.1515/zpch-1918-9209 Wassam, 1992, Statistical mechanics, 713 Müller, 1928, Zur allgemeinen Theorie der raschen Koagulation, Kolloidchem. Bech., 27, 223, 10.1007/BF02558510 M. Hounslow, Masters Course I, University of Sheffield, Sheffield, 2000 http://www.shef.ac.uk/uni/projects/ppg/pbe.htm Kapur, 1969, A coalescence model for granulation, Ind. Eng. Chem. Process Des. Dev., 8, 56, 10.1021/i260029a010 Kapur, 1981, Mathematical models of open-circuit balling or granulating devices, Ind. Eng. Chem. Process Des. Dev., 20, 519, 10.1021/i200014a022 Ramkrishna, 1985, The status of population balances, Rev. Chem. Eng., 3, 49, 10.1515/REVCE.1985.3.1.49 Cryer, 1999, Modelling agglomeration processes in fluid-bed granulation, AIChE J., 45, 2069, 10.1002/aic.690451005 Ouchiyama, 1975, The probability of coalescence in granulation kinetics, Ind. Eng. Chem. Process Des. Dev., 14, 286, 10.1021/i260055a016 Watano, 1995, Kinetics of granule growth in fluidized bed granulation with moisture control, Chem. Pharm. Bull., 43, 1764, 10.1248/cpb.43.1764 Watano, 1996, Mathematical model in the kinetics of agitation fluidized bed granulation. Effects of moisture content, damping speed and operation time on granule growth rate, Chem. Pharm. Bull., 44, 409, 10.1248/cpb.44.409 Ouchiyama, 1982, Kinetic analysis and simulation of batch granulation, Ind. Eng. Chem. Process Des. Dev., 21, 29, 10.1021/i200016a006 Timoshenko, 1951, 372 Ennis, 1991, A microlevel-based characterization of granulation phenomena, Powder Technol., 65, 257, 10.1016/0032-5910(91)80189-P Adetayo, 2000, A new approach to modelling granulation processes for simulation and control purposes, Powder Technol., 108, 202, 10.1016/S0032-5910(99)00221-1 Kristensen, 1985, Mechanical properties of moist agglomerates in relation to granulation mechanisms part II. Effects of particle size distribution, Powder Technol., 44, 239, 10.1016/0032-5910(85)85005-1 Drake, 1972, The scalar transport equation of coalescence theory: new families of exact solutions, J. Atmos. Sci., 29, 548, 10.1175/1520-0469(1972)029<0548:TSTEOC>2.0.CO;2 Pulvermacher, 1974, Similarity solutions of population balances, J. Colloid Interface Sci., 46, 428, 10.1016/0021-9797(74)90052-6 Adetayo, 1995, Population balance modelling of drum granulation of materials with wide size distribution, Powder Technol., 82, 37, 10.1016/0032-5910(94)02896-V Hounslow, 1988, A discretized population balance for nucleation, growth, and aggregation, AIChE J., 34, 1821, 10.1002/aic.690341108 Litster, 1995, Adjustable discretized population balance for growth and aggregation, AIChE J., 41, 591, 10.1002/aic.690410317 Gelbard, 1980, Sectional representations for simulating aerosol dynamics, J. Colloid Interface Sci., 76, 541, 10.1016/0021-9797(80)90394-X Abberger, 1994, Granule growth rates versus free humidity in fluid bed granulations, Eur. J. Pharm. Sci., 2, 110, 10.1016/0928-0987(94)90147-3 Abberger, 1999, Zur Kinetik der Wirbelschichtgranulierung, Pharmazie, 54, 611 Ormos, 1973, Studies on granulation in a fluidized bed III. Calculation of the feed rate of granulating liquid, Hung. J. Ind. Chem., 1, 463 Abberger, 1996, Instrumentation of a laboratory scale fluid-bed granulator for control of critical spray rate and of free moisture, Sci. Pharm., 64, 255 T. Abberger, H. Egermann, Die freie Feuchte als Kriterium für den Kornbildungsmechanismus bei der Wirbelschichtgranulierung, 11th Scientific Congress of the Austrian Pharmaceutical Society, Graz, Austria, 1994. 1994, 485 Spencer, 1980, HP-67/97 and TI-59 programs to fit the normal and log-normal distribution functions by linear regression, Powder Technol., 27, 219, 10.1016/0032-5910(80)85026-1 1987, 478 R. Nimylowytsch, Diplomarbeit, University of Innsbruck, Innsbruck, 1995. Ouchiyama, 1982, Kinetic analysis and simulation of batch granulation, Ind. Eng. Chem. Process Des. Dev., 21, 29, 10.1021/i200016a006 Liu, 2000, Coalescence of deformable granules in wet granulation processes, AIChE J., 46, 529, 10.1002/aic.690460312 Kristensen, 1996, Particle agglomeration in high shear mixers, Powder Technol., 88, 197, 10.1016/S0032-5910(96)03123-3 Kristensen, 1984, Granulation in high speed mixers part 4. Effect of liquid saturation on the agglomeration, Pharm. Ind., 46, 763 Holm, 1985, Granulation in high speed mixers part V. Power consumption and temperature changes during granulation, Powder Technol., 43, 213, 10.1016/0032-5910(85)80002-4 Huang, 1988, The granulation of partially prewetted alumina powders – a new concept in coalescence mechanism, Powder Technol., 55, 19, 10.1016/0032-5910(88)80084-6 Kristensen, 1993, Granulations, 121 Schaafsma, 1998, Description of agglomerate growth, Powder Technol., 97, 183, 10.1016/S0032-5910(97)03399-8 Waldie, 1991, Growth-mechanism and the dependence of granule size on drop size in fluidized-bed granulation, Chem. Eng. Sci., 46, 2781, 10.1016/0009-2509(91)85147-P Schaefer, 1977, Control of fluidized bed granulation II. Estimation of droplet size of atomized binder solutions, Arch. Pharm. Chem. Sci. Ed., 5, 178