The effect of cigarette smoking on early osseointegration of dental implants: a prospective controlled study

Clinical Oral Implants Research - Tập 27 Số 9 - Trang 1123-1128 - 2016
José Divino Bezerra Ferreira1, José Augusto Rodrigues1, Adriano Piattelli2, Giovanna Iezzi2, Sérgio Alexandre Gehrke1, Jamil Awad Shibli1
1Department of Periodontology and Oral Implantology, Dental Research Division, Guarulhos University, Guarulhos, SP, Brazil
2Department of Oral Medicine and Pathology University of Chieti‐Pescara Chieti Italy

Tóm tắt

AbstractObjectiveThis study evaluated the effect of cigarette smoking on the percentage of early bone‐to‐implant contact (BIC%), the bone density in the threaded area (BA%) as well as the bone density outside the threaded area (BD%) around micro‐implants with sandblasted acid‐etched surface retrieved from human jaws.Material and methodsTwenty‐two subjects (mean age 55.4 ± 4.5 years) were divided in two groups: smokers (n = 11 subjects) and never‐smokers (n = 11 subjects). Each subject received one micro‐implant during conventional mandible or maxilla implant surgery. After 8 weeks, the micro‐implants and the surrounding tissue were removed and prepared for histomorphometric analysis.ResultsTwo micro‐implants placed in smokers showed no osseointegration. Early stages of maturation of the newly formed bone were present, mainly in the never‐smokers. Marginal bone loss, gap, and fibrous tissue were present around some implants retrieved from smokers. Histometric evaluation indicated that the meanBIC% ranged between 25.9 ± 9.1 and 39.8 ± 14.2 for smokers and non‐smokers, respectively (P = 0.02). Smokers presented 28.6 ± 10.1 ofBA% while never‐smokers showed 46.4 ± 18.8 (P = 0.04). The mean ofBD% ranged between 19.1 ± 7.6 and 28.5 ± 18.8 for smokers and never‐smokers, respectively (P = 0.21).ConclusionCigarette smoking has a detrimental effect on early bone tissue response around sandblasted acid‐etched implant surface topographies.

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Tài liệu tham khảo

10.1111/j.1600-0501.2010.01977.x

Astrand P., 2008, Implant treatment of patients with edentulous jaws: a 20‐year follow‐up, Clinical Implant Dentistry and Related Research, 10, 207, 10.1111/j.1708-8208.2007.00081.x

10.1563/AAID-JOI-D-09-00018

Bain C.A., 1993, The association between the failure of dental implants and cigarette smoking, International Journal of Oral and Maxillofacial Implants, 8, 609

Balshe A.A., 2008, The effects of smoking on the survival of smooth‐ and rough‐surface dental implants, International Journal of Oral and Maxillofacial Implants, 23, 1117

10.1038/nchembio778

10.1002/jbm.b.30340

10.1016/S0901-5027(88)80047-X

Cesar‐Neto J.B., 2005, Bone density around titanium implants may benefit from smoking cessation: a histologic study in rats, International Journal of Oral and Maxillofacial Implants, 20, 713

10.1902/jop.2005.76.9.1476

10.1080/07853890310017576

10.1111/j.1600-0501.2008.01695.x

10.1080/00016470410001303

10.1177/154405910708601006

10.1016/j.biomaterials.2007.07.049

10.1034/j.1600-0501.1994.050410.x

DeLuca S., 2006, The effect of smoking on osseointegrated dental implants. Part II: peri‐implant bone loss, International Journal of Prosthodontics, 19, 560

Dohan Ehrenfest D.M., 2014, Identification card and codification of the chemical and morphological characteristics of 62 dental implant surfaces. Part 3: sand‐blasted/acid‐etched (SLA type) and related surfaces (Group 2A, main subtractive process), POSEIDO, 2, 37

10.1016/S0736-0266(02)00159-6

Gaston M.S., 2007, Inhibition of fracture healing, The Bone & Joint Journal, 89, 1553

10.1902/jop.2006.050325

10.1563/0-791.1

Iqbal M.M., 2000, Osteoporosis: epidemiology, diagnosis, and treatment, Southern Medical Journal, 93, 2

10.1007/BF02243003

10.1196/annals.1443.016

Misch C.E., 1990, Divisions of available bone in implant dentistry, International Journal of Oral Implantology, 7, 9

10.1172/JCI15153

10.1016/S0142-9612(96)00177-9

10.1016/S0142-9612(99)00160-X

10.1034/j.1600-051X.2003.300107.x

10.1111/j.1600-051X.2006.00907.x

Sennerby L., 1998, Surgical determinants of clinical success of osseointegrated oral implants: a review of the literature, International Journal of Prosthodontics, 11, 408

10.1097/ID.0b013e3180de4d64

10.1002/jbm.b.30608

10.1111/j.1708-8208.2009.00174.x

Shibli J.A., 2010, Influence of direct laser fabrication implant topography on type IV bone: a histomorphometric study in humans, Journal of Biomedical Materials Research part A, 93, 607, 10.1002/jbm.a.32566

10.1902/jop.2010.090493

10.1111/j.1600-051X.2007.01083.x

10.1016/S0378-5122(97)00070-4

10.1016/j.toxicon.2004.01.017

10.1016/S0014-2999(99)00551-8

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Clinical Oral Implants Research

Tập 27 Số 9

1123-1128

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