The disulfiram metabolites S-methyl-N,N-diethyldithiocarbamoyl sulfoxide and S-methyl-N,N-diethylthiocarbamoyl sulfone irreversibly inactivate betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, both in vitro and in situ, and arrest bacterial growth

Biochimie - Tập 93 - Trang 286-295 - 2011
Víctor J. Zaldívar-Machorro1, Manuel López-Ortiz2, Patricia Demare2, Ignacio Regla2, Rosario A. Muñoz-Clares1
1Departamento de Bioquímica, Facultad de Química, Universidad Nacional Autónoma de México, México D. F. 04510, México
2Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, México D. F. 09230, México