The depersonalized brain: New evidence supporting a distinction between depersonalization and derealization from discrete patterns of autonomic suppression observed in a non-clinical sample

Aderibigbe, 2001, Prevalence of depersonalization and derealization experiences in a rural population, Social Psychiatry and Psychiatric Epidemiology, 36, 63, 10.1007/s001270050291 Adolphs, 1994, Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala, Nature, 372, 669, 10.1038/372669a0 Adolphs, 1995, Fear and the human amygdala, Journal of Neuroscience, 15, 5879, 10.1523/JNEUROSCI.15-09-05879.1995 American Psychiatric Association, 2013, 302 Bechara, 2004, Listening to your heart: Interoceptive awareness as a gateway to feeling, Nature Neuroscience, 7, 102, 10.1038/nn0204-102 Ben-Shakhar, 1985, Standardization within individuals: A simple method to neutralize individual differences in skin condutance respones, Psychophysiology, 22, 292, 10.1111/j.1469-8986.1985.tb01603.x Ben-Shakhar, G. (1987). The correction of psychophysiological measures for individual differences in responsivity should be based on typical response parameters: A reply to Stemmler. Psychophysiology. Benjamini, 2010, Discovering the false discovery rate, Journal of the Royal Statistical Society. Series B: Statistical Methodology, 72, 405, 10.1111/j.1467-9868.2010.00746.x Benjamini, 1995, Controlling the false discovery rate: A practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B (Methodological), 57, 289, 10.1111/j.2517-6161.1995.tb02031.x Blanke, 2012, Multisensory brain mechanisms of bodily self-consciousness, Nature Reviews Neuroscience, 13, 556, 10.1038/nrn3292 Blanke, 2005, The out-of-body experience: Disturbed self-processing at the temporo-parietal junction, The Neuroscientist: A Review Journal Bringing Neurobiology, Neurology and Psychiatry, 11, 16, 10.1177/1073858404270885 Blanke, 2009, Full-body illusions and minimal phenomenal selfhood, Trends in Cognitive Sciences, 13, 7, 10.1016/j.tics.2008.10.003 Blanke, 2005, Linking out-of-body experience and self processing to mental own-body imagery at the, Journal of Neuroscience, 25, 550, 10.1523/JNEUROSCI.2612-04.2005 Botvinick, 1998, Rubber hands “feel” touch that eyes see, Nature, 391, 756, 10.1038/35784 Botvinick, 2005, Viewing facial expressions of pain engages cortical areas involved in the direct experience of pain, NeuroImage, 25, 312, 10.1016/j.neuroimage.2004.11.043 Boucsein, W. (2012). Electrodermal activity (2nd ed.) New York, NY: Springer. doi:http://doi.org/10.1007/978-1-4614-1126-0. Boucsein, 2012, Publication recommendations for electrodermal measurements, Psychophysiology, 49, 1017, 10.1111/j.1469-8986.2012.01384.x Braithwaite, 2014, Autonomic emotional responses to the induction of the rubber-hand illusion in those that report anomalous bodily experiences: Evidence for specific psychophysiological components associated with illusory body representations, Journal of Experimental Psychology. Human Perception and Performance, 40, 1131, 10.1037/a0036077 Braithwaite, 2013, Fractionating the unitary notion of dissociation: Disembodied but not embodied dissociative experiences are associated with exocentric perspective-taking, Frontiers in Human Neuroscience, 7, 719, 10.3389/fnhum.2013.00719 Braithwaite, 2011, Cognitive correlates of the spontaneous out-of-body experience (OBE) in the psychologically normal population: Evidence for an increased role of temporal-lobe instability, body-distortion processing, and impairments in own-body transformations, Cortex, 47, 839, 10.1016/j.cortex.2010.05.002 Braithwaite, 2017, Predisposition to Out-of-Body Experience (OBE) is associated with aberrations in multisensory integration: psychophysiological support from a “rubber hand illusion” study, Journal of Experimental Psychology: Human Perception and Performance, 43, 1125 Braithwaite, J., Watson, D. G., Jones, R., & Rowe, M. (2013). A guide for analysing electrodermal activity (EDA) & skin conductance responses (SCRs) for psychological experiments, 1–42. Brugger, 2002, Reflective mirrors: Perspective-taking in autoscopic phenomena, Cognitive Neuropsychiatry, 7, 179, 10.1080/13546800244000076 Bush, 1993, Transformations for within-subject designs: A Monte Carlo investigation, Psychological Bulletin, 113, 566, 10.1037/0033-2909.113.3.566 Clark, 2013, Whatever next? Predictive brains, situated agents, and the future of cognitive science, Behavioral and Brain Sciences, 36, 181, 10.1017/S0140525X12000477 Cohen, 1962, The statistical power of abnormal-social psychological research: A review, Journal of Abnormal and Social Psychology, 65, 145, 10.1037/h0045186 Cohen, 1992, A power primer, Psychological Bulletin, 112, 155, 10.1037/0033-2909.112.1.155 Corlett, 2009, From drugs to deprivation: A Bayesian framework for understanding models of psychosis, Psychopharmacology, 206, 515, 10.1007/s00213-009-1561-0 Corlett, 2007, From prediction error to psychosis: Ketamine as a pharmacological model of delusions, Journal of Psychopharmacology, 21, 238, 10.1177/0269881107077716 Corlett, 2010, Toward a neurobiology of delusions, Progress in Neurobiology, 92, 345, 10.1016/j.pneurobio.2010.06.007 Craig, 2002, How do you feel? Interoception: The sense of the physiological condition of the body, Nature Reviews. Neuroscience, 3, 655, 10.1038/nrn894 Craig, 2003, Interoception: The sense of the physiological condition of the body, Current Opinion in Neurobiology, 13, 500, 10.1016/S0959-4388(03)00090-4 Craig, 2009, How do you feel — now? The anterior insula and human awareness, Nature Reviews Neuroscience, 10, 59, 10.1038/nrn2555 Critchley, 2005, Neural mechanisms of autonomic, affective, and cognitive integration, Journal of Comparative Neurology, 493, 154, 10.1002/cne.20749 Critchley, 2004, Neural systems supporting interoceptive awareness, Nature Neuroscience, 7, 189, 10.1038/nn1176 Damasio, 2003, Feelings of emotion and the self, Annals of the New York Academy of Sciences, 1001, 253, 10.1196/annals.1279.014 Dawson, M. E., Schell, A. M., & Filion, D. L. (2007). The electrodermal system. In J. T. Cacioppo, L. G. Tassinary, & G. G. Bemston (Eds.), Handbook of psychophysiology (pp. 159–181). New York, NY: Cambridge University Press. doi:http://doi.org/10.1017/CBO9780511546396.007. Decety, 2006, The power of simulation: Imagining one’s own and other’s behavior, Brain Research, 1079, 4, 10.1016/j.brainres.2005.12.115 Decety, J., & Jackson, P. L. (2004). The functional architecture of human empathy. Behavioral and cognitive neuroscience reviews (Vol. 3). http://doi.org/10.1177/1534582304267187. Decety, 2006, Human empathy through the lens of social neuroscience, The Scientific World Journal, 6, 1146, 10.1100/tsw.2006.221 Decety, 2003, Shared representations between self and other: A social cognitive neuroscience view, Trends in Cognitive Sciences, 7, 527, 10.1016/j.tics.2003.10.004 Dewe, 2016, Uncomfortably numb: New evidence for suppressed emotional reactivity in response to body-threats in those predisposed to sub-clinical dissociative experiences, Cognitive Neuropsychiatry, 21, 377, 10.1080/13546805.2016.1212703 Dienes, 2018, Four reasons to prefer Bayesian analyses over significance testing, Psychonomic Bulletin & Review, 25, 207, 10.3758/s13423-017-1266-z Drabant, 2011, Experiential, autonomic, and neural responses during threat anticipation vary as a function of threat intensity and neuroticism, NeuroImage, 55, 401, 10.1016/j.neuroimage.2010.11.040 Ehrsson, 2007, The experimental induction of out-of-body experiences, Science, 317, 1048, 10.1126/science.1142175 Ehrsson, 2005, Touching a rubber hand: Feeling of body ownership is associated with activity in multisensory brain areas, Journal of Neuroscience, 25, 10564, 10.1523/JNEUROSCI.0800-05.2005 Ehrsson, 2004, That’s my hand! activity in premotor cortex reflects feeling of ownership of a limb, Science, 305, 875, 10.1126/science.1097011 Ehrsson, H. (2012). 43. The concept of body ownership and its relation to multisensory integration. Stein—The New Handbook of Multisensory Processes, 775–792. Friston, 2005, A theory of cortical responses, Philosophical Transactions of the Royal Society of London Series B, Biological Sciences, 360, 815, 10.1098/rstb.2005.1622 Friston, 2010, The free-energy principle: A unified brain theory?, Nature Reviews. Neuroscience, 11, 127, 10.1038/nrn2787 Gallagher, 2000, Philosophical conceptions of the self: Implications for cognitive science, Trends in Cognitive Sciences, 4, 14, 10.1016/S1364-6613(99)01417-5 Giesbrecht, 2010, Skin conductance and memory fragmentation after exposure to an emotional film clip in depersonalization disorder, Psychiatry Research, 177, 342, 10.1016/j.psychres.2010.03.010 Grèzes, 2001, Functional anatomy of execution, mental simulation, observation, and verb generation of actions: A meta-analysis, Human Brain Mapping, 12, 1, 10.1002/1097-0193(200101)12:1<1::AID-HBM10>3.0.CO;2-V Hohwy, 2010, Explaining away the body: Experiences of supernaturally caused touch and touch on non-hand objects within the rubber hand illusion, PLoS ONE, 5, 1, 10.1371/journal.pone.0009416 Hunter, 2003, Depersonalisation disorder: A cognitive-behavioural conceptualisation, Behaviour Research and Therapy, 41, 1451, 10.1016/S0005-7967(03)00066-4 Hunter, 2004, The epidemiology of depersonalisation and derealisation - A systematic review, Social Psychiatry and Psychiatric Epidemiology, 39, 9, 10.1007/s00127-004-0701-4 Hutchison, 1999, Pain-related neurons in the human cingulate cortex, Nature Neuroscience, 2, 403, 10.1038/8065 Jackson, 2006, Empathy examined through the neural mechanisms involved in imagining how I feel versus how you feel pain, Neuropsychologia, 44, 752, 10.1016/j.neuropsychologia.2005.07.015 Jackson, 2005, How do we perceive the pain of others? A window into the neural processes involved in empathy, NeuroImage, 24, 771, 10.1016/j.neuroimage.2004.09.006 Jackson, 2006, Neural circuits involved in imitation and perspective-taking, Neuroimage, 31, 429, 10.1016/j.neuroimage.2005.11.026 Jackson, 2006, To what extent do we share the pain of others? Insight from the neural bases of pain empathy, Pain, 125, 5, 10.1016/j.pain.2006.09.013 Jarosz, 2014, What are the odds? A practical guide to computing and reporting Bayes Factors, Journal of Problem Solving, 7, 2, 10.7771/1932-6246.1167 JASP Team (2017). JASP (Version 0.8.1.2) [Computer software]. Jay, 2014, Testing a neurobiological model of depersonalization disorder using repetitive transcranial magnetic stimulation, Brain Stimulation, 7, 252, 10.1016/j.brs.2013.12.002 Jeffreys, 1961 Johns, 2001, The continuity of psychotic experiences in the general population, Clinical Psychology Review, 21, 1125, 10.1016/S0272-7358(01)00103-9 Kessler, 2016, Deliberate and spontaneous sensations of disembodiment: Capacity or flaw?, Cognitive Neuropsychiatry, 21, 412, 10.1080/13546805.2016.1203769 Kessler, 2014, A cross-culture, cross-gender comparison of perspective taking mechanisms, Proceedings of the Royal Society of London B: Biological Sciences, 281, 20140388, 10.1098/rspb.2014.0388 Kammers, 2011, Feeling numb: Temperature, but not thermal pain, modulates feeling of body ownership, Neuropsychologia, 49, 1316, 10.1016/j.neuropsychologia.2011.02.039 Kass, 1995, Bayes Factors, Journal of the American Statistical Association, 90, 773, 10.1080/01621459.1995.10476572 Lambert, 2001, Primary and secondary depersonalisation disorder: A psychometric study, Journal of Affective Disorders, 63, 249, 10.1016/S0165-0327(00)00197-X Lamm, 2007, The neural substrate of human empathy: Effects of perspective-taking and cognitive appraisal, Journal of Cognitive Neuroscience, 19, 42, 10.1162/jocn.2007.19.1.42 Lawrence, 2007, Empathy and enduring depersonalization: The role of self-related processes, Social Neuroscience, 2, 292, 10.1080/17470910701391794 Lemche, 2008, Cerebral and autonomic responses to emotional facial expressions in depersonalisation disorder, British Journal of Psychiatry, 193, 222, 10.1192/bjp.bp.107.044263 Lemche, 2007, Limbic and prefrontal responses to facial emotion expressions in depersonalization, Neuroreport, 18, 473, 10.1097/WNR.0b013e328057deb3 Lenggenhager, 2007, Video ergo sum: Manipulating bodily self-consciousness, Science, 317, 1096, 10.1126/science.1143439 Lenggenhager, 2009, Spatial aspects of bodily self-consciousness, Consciousness and Cognition, 18, 110, 10.1016/j.concog.2008.11.003 Marsman, 2016, Bayesian benefits with JASP, European Journal of Developmental Psychology, 5629, 1 Myachykov, 2014, TEST: A tropic, embodied, and situated theory of cognition, Topics in cognitive science, 6, 442, 10.1111/tops.12024 Medford, 2012, Emotion and the unreal self: Depersonalization disorder and de-affectualization, Emotion Review, 4, 139, 10.1177/1754073911430135 Medford, 2006, Emotional memory in depersonalization disorder: A functional MRI study, Psychiatry Research - Neuroimaging, 148, 93, 10.1016/j.pscychresns.2006.05.007 Medford, 2010, Conjoint activity of anterior insular and anterior cingulate cortex: Awareness and response, Brain Structure and Function, 1–15 Medford, 2005, Understanding and treating depersonalisation disorder, Advances in Psychiatric Treatment, 11, 92, 10.1192/apt.11.2.92 Michal, 2009, Prevalence, correlates, and predictors of depersonalization experiences in the german general population, The Journal of Nervous and Mental Disease, 197, 499, 10.1097/NMD.0b013e3181aacd94 Morrison, 2004, Vicarious responses to pain in anterior cingulate cortex: Is empathy a multisensory issue?, Cognitive, Affective, & Behavioral Neuroscience, 4, 270, 10.3758/CABN.4.2.270 Moseley, 2008, Psychologically induced cooling of a specific body part caused by the illusory ownership of an artificial counterpart, Proceedings of the National Academy of Sciences of the United States of America, 105, 13169, 10.1073/pnas.0803768105 Niedenthal, 2005, Embodiment in attitudes, social perception, and emotion, Personality and Social Psychology Review, 9, 184, 10.1207/s15327957pspr0903_1 Nikula, 1991, Psychological correlates of nonspecific skin-conductance responses, Psychophysiology, 28, 86, 10.1111/j.1469-8986.1991.tb03392.x Paton, 2012, The rubber hand illusion reveals proprioceptive and sensorimotor differences in autism spectrum disorders, Journal of Autism and Developmental Disorders, 42, 1870, 10.1007/s10803-011-1430-7 Phillips, 2001, Depersonalization disorder: Thinking without feeling, Psychiatry Research - Neuroimaging, 108, 145, 10.1016/S0925-4927(01)00119-6 Phillips, 2003, Depersonalization disorder: A functional neuroanatomical perspective, Stress, 6, 157, 10.1080/1025389031000138538 Preston, 2002, Empathy: Its ultimate and proximate bases, Behavioral and Brain Sciences, 25, 1, 10.1017/S0140525X02000018 Price, 2000, Psychological and neural mechanisms of the affective dimension of pain, Science, 288, 1769, 10.1126/science.288.5472.1769 Raftery, 1995, Bayesian model selection in social research, Sociological Methodology, 25, 111, 10.2307/271063 Rohde, 2013, The human touch: Skin temperature during the rubber hand illusion in manual and automated stroking procedures, PLoS ONE, 8, 1, 10.1371/journal.pone.0080688 Rosen, 1955, The reconstruction of a traumatic childhood event in a case of derealization, Journal of the American Psychoanalytic Association, 3, 211, 10.1177/000306515500300203 Rouder, 2009, Bayesian t tests for accepting and rejecting the null hypothesis, Psychonomic Bulletin & Review, 16, 225, 10.3758/PBR.16.2.225 Ruby, 2004, How would you feel versus how do you think she would feel? A neuroimaging study of perspective-taking with social emotions, Journal of Cognitive Neuroscience, 16, 988, 10.1162/0898929041502661 Saarela, 2007, The compassionate brain: Humans detect intensity of pain from another’s face, Cerebral Cortex, 17, 230, 10.1093/cercor/bhj141 Sadibolova, 2014, Seeing the body produces limb-specific modulation of skin temperature, Biology Letters, 10, 20140157, 10.1098/rsbl.2014.0157 Sass, 2013, Anomalous self-experience in depersonalization and schizophrenia: A comparative investigation, Consciousness and Cognition, 22, 430, 10.1016/j.concog.2013.01.009 Sedeño, 2014, How do you feel when you can’t feel your body? Interoception, functional connectivity and emotional processing in depersonalization-derealization disorder, PLoS ONE, 9, 10.1371/journal.pone.0098769 Seifert, 2013, Brain activity during sympathetic response in anticipation and experience of pain, Human Brain Mapping, 34, 1768, 10.1002/hbm.22035 Seth, 2009, Explanatory correlates of consciousness: Theoretical and computational challenges, Cognitive Computation, 1, 50, 10.1007/s12559-009-9007-x Seth, 2013, Interoceptive inference, emotion, and the embodied self, Trends in Cognitive Sciences, 17, 565, 10.1016/j.tics.2013.09.007 Seth, 2016, Active interoceptive inference and the emotional brain, Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 371, 20160007, 10.1098/rstb.2016.0007 Seth, 2012, An interoceptive predictive coding model of conscious presence, Frontiers in Psychology, 2, 1, 10.3389/fpsyg.2011.00395 Sierra, 2009 Sierra, 2005, Unpacking the depersonalization syndrome: An exploratory factor analysis on the Cambridge Depersonalization Scale, Psychological Medicine, 35, 1523, 10.1017/S0033291705005325 Sierra, 1998, Depersonalization: Neurobiological perspectives, Biological Psychiatry, 44, 898, 10.1016/S0006-3223(98)00015-8 Sierra, 2000, The Cambridge Depersonalisation Scale: A new instrument for the measurement of depersonalisation, Psychiatry Research, 93, 153, 10.1016/S0165-1781(00)00100-1 Sierra, 2001, The phenomenological stability of depersonalization: Comparing the old with the new, Journal of Nervous and Mental Disease, 189, 629, 10.1097/00005053-200109000-00010 Sierra, 2011, Depersonalization: A selective impairment of self-awareness, Consciousness and Cognition, 20, 99, 10.1016/j.concog.2010.10.018 Sierra, 2002, Separating depersonalisation and derealisation: The relevance of the “lesion method”, Journal of Neurology, Neurosurgery, and Psychiatry, 72, 530 Sierra, 2002, Autonomic response in depersonalization disorder, Archives of General Psychiatry, 59, 833, 10.1001/archpsyc.59.9.833 Sierra, 2006, Autonomic response in the perception of disgust and happiness in depersonalization disorder, Psychiatry Research, 145, 225, 10.1016/j.psychres.2005.05.022 Singer, 2009, The social neuroscience of empathy, Annals of the New York Academy of Sciences, 1156, 81, 10.1111/j.1749-6632.2009.04418.x Singer, 2004, Empathy for pain involves the affective but not sensory components of pain, Science (New York, N.Y.), 303, 1157, 10.1126/science.1093535 Suzuki, 2013, Multisensory integration across exteroceptive and interoceptive domains modulates self-experience in the rubber-hand illusion, Neuropsychologia, 51, 2909, 10.1016/j.neuropsychologia.2013.08.014 Thakkar, 2011, Disturbances in body ownership in schizophrenia: Evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience, PLoS ONE, 6, e27089, 10.1371/journal.pone.0027089 van Os, 2000, Strauss (1969) revisited: A psychosis continuum in the general population?, Schizophrenia Research, 45, 11, 10.1016/S0920-9964(99)00224-8 Verdoux, 2002, Psychotic symptoms in non-clinical populations and the continuum of psychosis, Schizophrenia Research, 54, 59, 10.1016/S0920-9964(01)00352-8 Vinkers, 2013, The effect of stress on core and peripheral body temperature in humans, Stress, 16, 520, 10.3109/10253890.2013.807243 Wagenmakers, E. J., Love, J., Marsman, M., Jamil, T., Ly, A., Verhagen, J., … Morey, R. D. (2017). Bayesian inference for psychology. Part II: Example applications with JASP. Psychonomic Bulletin & Review. http://doi.org/10.3758/s13423-017-1323-7. Wang, 2016, Rhythm makes the world go round: An MEG-TMS study on the role of right TPJ theta oscillations in embodied perspective taking, Cortex, 75, 68, 10.1016/j.cortex.2015.11.011 Wang, 2007, Observations of upper-extremity skin temperature and corresponding overall-body thermal sensations and comfort, Building and Environment, 42, 3933, 10.1016/j.buildenv.2006.06.035 World Health Organization (WHO: 1992). F48.1. Depersonalisation-derealisation syndrome. In The ICD-10 classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. Geneva: World Health Organization.