The coupling of bone formation to bone resorption: A critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis

Arnold, 1981, Trabecular pattern and shapes in aging and osteoporosis, 297 Baron, 1981, Reversal phase and osteopenia: Defective coupling of resorption to formation in the pathogenesis of osteoporosis, 311 Baron, 1981, The significance of lacunar erosion without osteoclasts: Studies on the reversal phase of the remodeling sequence, 35 Baylink, 1979, The regulation of endosteal bone volume, J. Periodontol., 50, 43, 10.1902/jop.1979.50.4s.43 Bordier, 1976, Morphological and morphometrical characteristics of the mineralizalion front. A vitamin D regulated sequence of the bone remodelling Burch, 1964 Cann, 1980, Spinal mineral loss in oophorectomized women, JAMA, 244, 2056, 10.1001/jama.1980.03310180022025 Crilly, 1978, Post-menopausal and corticosteroid-induced osteoporosis, Front, Hormone Res., 5, 53, 10.1159/000401985 Courpron, 1981, Mechanisms underlying the reduction with age of the mean wall thickness of trabecular basic structure unit (BSU) in human iliac bone, 323 Darby, 1981, Mean wall thickness and formation periods of trabecular bone packets in idiopathic osteoporosis, Calcif. Tissue Int., 33, 199, 10.1007/BF02409438 Farley, 1981, A putative coupling factor from human bone: Effects on bone cells in vitro, Calcified Tissue International, 33, 292 Frost, 1964, Dynamics of bone remodeling Frost, 1966 Frost, 1973, The origin and nature of transients in human bone remodeling dynamics, 124 Harris, 1969, Skeletal renewal and metabolic bone disease, N. Engl J. Med., 280, 193, 10.1056/NEJM196901232800405 Hayfiick, 1976, The cell biology of human aging, N. Engl. J. Med., 295, 1302, 10.1056/NEJM197612022952308 Heaney, 1978, Menopausal changes in calcium balance performance, J. Lab. Clin. Med., 92, 953 Heaney, 1978, Menopausal changes in bone remodeling, J. Lab. Clin. Med., 92, 964 Howard, 1980, Evidence for the coupling of bone formation to bone resorption in vitro, Metab. Bone. Dis. & Rel. Res., 2, 131, 10.1016/0221-8747(80)90009-0 Ivey, 1981, Postmenopausal osteoporosis: Proposed roles of defective coupling and estrogen deficiency, Metab. Bone, Dis. & Ref. Res., 3, 3, 10.1016/S0221-8747(81)80016-1 Jaworski, 1980, Study of cell kinetics within evolving secondary Haversian systems, J. Anal., 131, 91 Jaworski, 1981, Physiology and pathology of bone remodeling. Cellular basis of bone structure in health and in osteoporosis, Orthop. Clin. North. Am., 12, 485, 10.1016/S0030-5898(20)31368-7 Jee, 1976, Bone cell origin at the endosteal surface, 113 Johnson, 1964, Morphologic analysis in pathology: the kinetics of disease and general biology of bone, 543 Lauffenburger, 1977, Bone remodeling and calcium metabolism: A correlated histomorphometric calcium kinetic, and biochemical study in patients with osteoporosis and Paget's disease, Metabolism, 26, 589, 10.1016/0026-0495(77)90081-6 Lindsay, 1976, Long-term prevention of postmenopausal osteoporosis by oestrogen: Evidence for an increased bone mass after delayed onset of oestrogen treatment, Lancet, 1, 1038, 10.1016/S0140-6736(76)92217-0 Lindsay, 1980, Prevention of spinal osteoporosis in oophorectomized women, Lancet, 2, 1151, 10.1016/S0140-6736(80)92592-1 Lips, 1978, Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age, Calcif. Tissue. Res., 26, 13, 10.1007/BF02013227 Malm, 1958, Calcium requirement and adaptation in adult men, Scand. J. Clin. Lab. Invest., 10 Marotti, 1976, Decrement in volume of osteoblasts during osteon formation and its effect on the size of the corresponding osteocytes Meunier, 1971, Osteoporosis and the replacement of cell populations of the marrow by adipose tissue: A quantitative study of 84 iliac bone biopsies, Clio. Orthop., 80, 147, 10.1097/00003086-197110000-00021 Nordin, 1979, The treatment of postmenopausal osteoporosis Parfitt, 1979, Quantum concept of bone remodeling and turnover: Implications for the pathogenesis of osteoporosis, Calcif. Tissue. Int., 28, 1, 10.1007/BF02441211 Parfitt, 1980, Morphologic basis of bone mineral measurements: Transient and steady state effects of treatment in osteoporosis, Mineral Electrolyte Metab., 4, 273 Parfitt, 1981, Kinetics of matrix and mineral apposition in osteoporosis and renal osteodystrophy: Relationship to rate of turnover and to cell morphology, 213 Parfitt, 1981, Impaired osteoblast function in metabolic bone disease, 321 Parfitt, 1981, Bone remodeling in the pathogenesis of osteoporosis, Resident and Staff Physician, 60 Parfitt, 1981, Bone remodeling in the pathogenesis of osteoporosis, Resident and Staff Physician, 71 Parfitt A.M.The physiologic and clinical significance of bone histomorphometric data. In: Bone Histomorphometry: Techniques and Interpretations, R. Recker, ed., C.R.C. Press, Cleveland, in press, b. Raisz, 1978, Hormonal regulation of bone formation, Rec. Prog. Horm. Res., 34, 335 Rasmussen, 1974, The Physiological and Cellular Basis of Metabolic Bone Disease, 364 Riggs, 1981, Osteoporosis - a disease of impaired homeostatic regulation?, Mineral Electrolyte Metab., 5, 265 Thompson, 1975, Increases in number and size of osteoclasts in response to calcium or phosphorus deficiency in the rat, Endocrinology, 97, 283, 10.1210/endo-97-2-283 1941