The compliance and burden of treatment with the epinephrine auto‐injector in food‐allergic adolescents

Pediatric Allergy and Immunology - Tập 27 Số 1 - Trang 28-34 - 2016
J. Saleh‐Langenberg1,2, Bertine M.J. Flokstra-de Blok3,2, Nicole J. Goossens1,2, Jozephina C Kemna1, J.L. van Velde3,2, A. E. J. Dubois1,2
1Department of Pediatric Pulmonology and Pediatric Allergy, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2GRIAC research institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
3Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

Tóm tắt

AbstractBackgroundFood‐allergic patients at high risk of potential fatal anaphylaxis should carry an epinephrine auto‐injector (EAI) at all times. This treatment may be perceived as burdensome and this may affect compliance and health‐related quality of life (HRQL). The aims of the study were (1) to determine the burden of treatment (BoT) of an EAI, (2) to examine the relationship between this burden and compliance, and (3) to analyze which factors contribute to the BoT of the EAI as perceived by food‐allergic adolescents and their parents.MethodsDutch food‐allergic adolescents prescribed an EAI, and their parents completed a questionnaire package (n = 55). Relationships between BoT and HRQL, illness severity and perception, and anxiety measures were investigated.ResultsFood‐allergic adolescents and their parents were (extremely) positive about the EAI (54.5%; 72.7%, respectively) (=low BoT). The BoT measure showed a significantly greater burden in food‐allergic adolescents prescribed an EAI who reported not carrying the EAI at all times than adolescents who reported they did. The BoT scores of both adolescents and their parents were not associated with HRQL, illness severity and perception, or trait anxiety.ConclusionsThe majority of food‐allergic adolescents and their parents were positive about the EAI (=low BoT). However, the BoT was significantly associated with self‐reported compliance with carrying the EAI. The BoT was higher in food‐allergic adolescents prescribed an EAI who reported not carrying the EAI at all times. The BoT measure seems to be a useful tool to study compliance with carrying an EAI. The BoT of an EAI is not associated with HRQL. The BoT measures a distinct concept related to compliance behavior.

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Tài liệu tham khảo

10.1002/0470861193.ch10

10.1016/j.jaci.2006.12.622

10.1111/j.1398-9995.2007.01421.x

10.1016/j.jaci.2009.05.028

10.4104/pcrj.2012.00072

10.1016/j.jaci.2006.03.049

10.1111/jpc.12794

10.1016/j.jaci.2012.09.038

MacKenzie H, 2010, Teenagers’ experiences of living with food hypersensitivity: a qualitative study, Pediatr Allergy Immunol, 21, 595

10.1111/pai.12013

10.1111/j.1365-2222.2010.03586.x

10.1111/j.1399-3038.2009.00975.x

10.1111/j.1365-2222.2007.02758.x

10.1111/j.1365-2222.2011.03912.x

10.1067/mai.2002.125827

10.1111/j.1365-2222.2008.03120.x

10.1016/j.jaci.2008.05.008

10.1111/j.1398-9995.2009.02216.x

10.1016/j.jpsychores.2005.10.020

Master thesis. Patient's illness perception: An additional part of physiotherapy assessment. Cross‐cultural adaptation and measurement properties of the brief illness perception questionnaire ‐ Dutch language version; 2007.

Spielberger CD, 1984, Manual for the state‐trait anxiety inventory (STAI)

Rolison MR, 2002, Factors influencing adolescents’ decisions to engage in risk‐taking behavior, Adolescence, 37, 585

10.1016/j.jaci.2007.01.021

10.1056/NEJM199208063270603

10.1111/j.1365-2222.2011.03743.x

10.1586/erp.10.44

10.1542/peds.105.2.359

10.1046/j.1365-2222.2000.00864.x

10.1097/ACI.0b013e32833bc670

10.1111/j.1399-3038.2010.01005.x

Thông tin
Thông tin xuất bản

Pediatric Allergy and Immunology

Tập 27 Số 1

28-34

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