The challenge of enzyme cost in the production of lignocellulosic biofuels

Biotechnology and Bioengineering - Tập 109 Số 4 - Trang 1083-1087 - 2012
Daniel Klein‐Marcuschamer1,2, Piotr Oleśkowicz-Popiel1,2, Blake A. Simmons1,2,3, Harvey W. Blanch4,5,1,2
1Joint Bioenergy Institute, 5885 Hollis St. Emeryville, California 94608
2Physical Biosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California, 94720
3Sandia National Laboratories, Biomass Science and Conversion Technology Department, Livermore, California
4Department of Chemical Engineering, University of California, Berkeley, California 94720. T: (510) 486-7069
5F: (510) 486-4252

Tóm tắt

AbstractWith the aim of understanding the contribution of enzymes to the cost of lignocellulosic biofuels, we constructed a techno‐economic model for the production of fungal cellulases. We found that the cost of producing enzymes was much higher than that commonly assumed in the literature. For example, the cost contribution of enzymes to ethanol produced by the conversion of corn stover was found to be $0.68/gal if the sugars in the biomass could be converted at maximum theoretical yields, and $1.47/gal if the yields were based on saccharification and fermentation yields that have been previously reported in the scientific literature. We performed a sensitivity analysis to study the effect of feedstock prices and fermentation times on the cost contribution of enzymes to ethanol price. We conclude that a significant effort is still required to lower the contribution of enzymes to biofuel production costs. Biotechnol. Bioeng. 2012; 109:1083–1087. © 2011 Wiley Periodicals, Inc.

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