The cell cycle restricts activation-induced cytidine deaminase activity to early G1
Tóm tắt
Từ khóa
Tài liệu tham khảo
Alt, 2013, Mechanisms of programmed DNA lesions and genomic instability in the immune system, Cell., 152, 417, 10.1016/j.cell.2013.01.007
Anderson, 2007, Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum, Nat. Cell Biol., 9, 1160, 10.1038/ncb1636
Casellas, 2016, Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity, Nat. Rev. Immunol., 16, 164, 10.1038/nri.2016.2
Chaudhuri, 2003, Transcription-targeted DNA deamination by the AID antibody diversification enzyme, Nature., 422, 726, 10.1038/nature01574
Crouch, 2007, Regulation of AID expression in the immune response, J. Exp. Med., 204, 1145, 10.1084/jem.20061952
Dickerson, 2003, AID mediates hypermutation by deaminating single stranded DNA, J. Exp. Med., 197, 1291, 10.1084/jem.20030481
Di Noia, 2007, Molecular mechanisms of antibody somatic hypermutation, Annu. Rev. Biochem., 76, 1, 10.1146/annurev.biochem.76.061705.090740
Doi, 2003, De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination, Proc. Natl. Acad. Sci. USA., 100, 2634, 10.1073/pnas.0437710100
Endres, 2004, Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase, J. Clin. Invest., 113, 1711, 10.1172/JCI200420926
Faili, 2002, AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line, Nat. Immunol., 3, 815, 10.1038/ni826
Gasnereau, 2007, Flow cytometry to sort mammalian cells in cytokinesis, Cytometry A., 71, 1, 10.1002/cyto.a.20352
Hagen, 2008, Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA, EMBO J., 27, 51, 10.1038/sj.emboj.7601958
Haug, 1998, Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase, Nucleic Acids Res., 26, 1449, 10.1093/nar/26.6.1449
Horváth, 2010, A one-step method for quantitative determination of uracil in DNA by real-time PCR, Nucleic Acids Res., 38, e196, 10.1093/nar/gkq815
Kaikkonen, 2013, Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription, Mol. Cell., 51, 310, 10.1016/j.molcel.2013.07.010
Lackey, 2012, APOBEC3B and AID have similar nuclear import mechanisms, J. Mol. Biol., 419, 301, 10.1016/j.jmb.2012.03.011
Lackey, 2013, Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination, Cell Cycle., 12, 762, 10.4161/cc.23713
Le, 2015, Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID, PLoS Genet., 11, e1005411, 10.1371/journal.pgen.1005411
McBride, 2004, Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase, J. Exp. Med., 199, 1235, 10.1084/jem.20040373
Meng, 2014, Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability, Cell., 159, 1538, 10.1016/j.cell.2014.11.014
Methot, 2015, Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm, J. Exp. Med., 212, 581, 10.1084/jem.20141157
Muramatsu, 2000, Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme, Cell., 102, 553, 10.1016/S0092-8674(00)00078-7
Patenaude, 2009, Active nuclear import and cytoplasmic retention of activation-induced deaminase, Nat. Struct. Mol. Biol., 16, 517, 10.1038/nsmb.1598
Pefanis, 2014, Noncoding RNA transcription targets AID to divergently transcribed loci in B cells, Nature., 514, 389, 10.1038/nature13580
Petersen, 2001, AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching, Nature., 414, 660, 10.1038/414660a
Qian, 2014, B cell super-enhancers recruit AID tumorigenic activity, Cell., 159, 1524, 10.1016/j.cell.2014.11.013
Robbiani, 2013, Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase, Annu. Rev. Pathol., 8, 79, 10.1146/annurev-pathol-020712-164004
Robbiani, 2015, Plasmodium infection promotes genomic instability and AID-dependent B cell lymphoma, Cell., 162, 727, 10.1016/j.cell.2015.07.019
Sakaue-Sawano, 2008, Visualizing spatiotemporal dynamics of multicellular cell-cycle progression, Cell., 132, 487, 10.1016/j.cell.2007.12.033
Santaguida, 2015, Short- and long-term effects of chromosome mis-segregation and aneuploidy, Nat. Rev. Mol. Cell Biol., 16, 473, 10.1038/nrm4025
Victora, 2010, Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter, Cell., 143, 592, 10.1016/j.cell.2010.10.032
Wang, 2014, Epigenetic targeting of activation-induced cytidine deaminase, Proc. Natl. Acad. Sci. USA., 111, 18667, 10.1073/pnas.1420575111
Yeap, 2015, Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes, Cell., 163, 1124, 10.1016/j.cell.2015.10.042
Yu, 2003, R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells, Nat. Immunol., 4, 442, 10.1038/ni919