The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin Modelling and structural relationships

FEBS Journal - Tập 187 Số 2 - Trang 341-352 - 1990
Albrecht Messerschmidt1, Robert Huber1
1Max-Planck Institut für Biochemie, Martinsried

Tóm tắt

On the basis of the spatial structure of ascorbate oxidase [Messerschmidt, A., Rossi, A., Ladenstein, R., Huber, R., Bolognesi, M., Gatti, G., Marchesini, A., Petruzzelli, R. & Finazzi‐Agro, A. (1989) J. Mol. Biol. 206, 513–529], an alignment of the amino acid sequence of the related blue oxidases, laccase and ceruloplasmin is proposed. This strongly suggests a three‐domain structure for laccase closely related to ascorbate oxidase and a six‐domain structure of ceruloplasmin. These domains demonstrate homology with the small blue copper proteins. The relationships suggest that laccase, like ascorbate oxidase, has a mononuclear blue copper in domain 3 and a trinuclear copper between domain 1 and 3 and ceruloplasmin has mononuclear copper ions in domains 2, 4 and 6 and a trinuclear copper between domains 1 and 6.

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Tài liệu tham khảo

10.1002/9780470122785.ch4

10.1146/annurev.bi.51.070182.000321

Mondovi B., 1984, Copper proteins and copper enzymes, 101

Dawson C. R., 1966, The Biochemistry of copper, 305

10.1021/ba-1982-0200.ch010

10.1016/S1874-6047(08)60231-0

Reinhammar B., 1981, Copper proteins, 104

Reinhammer B., 1984, Copper proteins and copper enzymes, 1

Cooper E., 1979, Invest. Cell Pathol., 2, 293

10.1016/B978-0-12-568402-6.50014-2

Rydén L., 1984, Copper proteins and copper enzymes, 34

10.1073/pnas.81.2.390

10.1073/pnas.83.14.5086

10.1016/S0021-9258(19)35436-5

Froehner S. C., 1974, J. Bacteriol., 120, 458, 10.1128/jb.120.1.458-465.1974

10.1016/0005-2795(78)90470-1

10.1073/pnas.86.4.1239

10.1016/0022-2836(89)90498-1

10.1007/BFb0116549

Strothkamp K. G.(1973)PhD Thesis Columbia University New York .

10.1021/bi00700a006

10.1016/0014-5793(74)80736-2

10.1111/j.1432-1033.1979.tb04217.x

10.1073/pnas.83.23.8854

10.1073/pnas.81.15.4761

10.1016/S0022-2836(83)80064-3

10.1002/ijch.198100003

10.1016/S0022-2836(83)80216-2

10.1107/S0108768188008912

10.1016/S0021-9258(17)31227-9

10.1073/pnas.78.5.2805

10.1073/pnas.79.22.6767

Moshkov K. A., 1987, Mol. Biol. (Mosc), 21, 1124

10.1107/S0021889878013308

Dayhoff M. O., 1978, Atlas of protein sequence and structure, 345

10.1038/312337a0

10.1073/pnas.83.18.6800

10.1016/0005-2795(73)90112-8

10.1111/j.1432-1033.1971.tb01523.x

Ambler R. P., 1980, Poplar plastocyanin structure

Rydén L., 1988, Oxidases and related redox systems, 349

George D. G., 1988, Multiple sequence alignment program ALNED

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FEBS Journal

Tập 187 Số 2

341-352

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