The admixture model in linkage analysis

Journal of Statistical Planning and Inference - Tập 130 - Trang 317-324 - 2005
Jie Peng1, D. Siegmund1
1Department of Statistics, Stanford University, Stanford, CA 94305 USA

Tài liệu tham khảo

Chen, 1998, Penalized likelihood-ratio test for finite mixture models with multinomial observations, Canad. J. Statist., 26, 583, 10.2307/3315719 Chernoff, 1995, Asymptotic distribution of the likelihood ratio test that a mixture of two binomials is a single binomial, J. Statist. Plann. Inference, 43, 19, 10.1016/0378-3758(94)00006-H Chiu, 2002, Multipoint linkage detection in the presence of heterogeneity, Biostatistics, 3, 195, 10.1093/biostatistics/3.2.195 Darvasi, 1993, Detecting marker—QTL linkage and estimating QTL gene effect and map location using a saturated genetic map, Genetics, 134, 943, 10.1093/genetics/134.3.943 Davies, 1977, Hypothesis testing when a nuisance parameter is present only under the alternative, Biometrika, 64, 247, 10.2307/2335690 Davies, 1987, Hypothesis testing when a nuisance parameter is present only under the alternative, Biometrika, 74, 33 Dupuis, 1999, Statistical methods for mapping quantitative trait loci from a dense set of markers, Genetics, 151, 373, 10.1093/genetics/151.1.373 Faraway, 1993, Distribution of the admixture test for the detection of linkage under heterogeneity, Genet. Epidemiol., 10, 75, 10.1002/gepi.1370100108 Feingold, 1993, Gaussian models for genetic linkage analysis using complete high resolution maps of identity-by-descent, Amer. J. Hum. Genet., 53, 234 Lander, 1986, Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphis. Proc, Nat. Acad. Sci. USA, 83, 7353, 10.1073/pnas.83.19.7353 Lander, 1989, Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps, Genetics, 121, 185, 10.1093/genetics/121.1.185 Leadbetter, 1983 Lemdani, 1995, Tests for genetic linkage and homogeneity, Biometrics, 51, 1033, 10.2307/2533002 Liang, 1999, Hypothesis testing under mixture models, Biometrics, 55, 65, 10.1111/j.0006-341X.1999.00065.x Rabinowitz, 1997, The approximate distribution of the maximum of a smoothed Poisson random field, Statistica Sinica, 7, 167 Rebai, 1994, Approximate thresholds of interval mapping test for QTL detection, Genetics, 138, 235, 10.1093/genetics/138.1.235 Rebai, 1995, Comparing power of different methods for QTL detection, Biometrics, 51, 87, 10.2307/2533317 Shoukri, 1993, Statistical testing of genetic linkage under heterogeneity, Biometrics, 49, 151, 10.2307/2532610 Siegmund, 2003, Significance level in interval mapping, 10 Smith, 1963, Testing for heterogeneity of recombination fraction values in human genetics, Ann. Hum. Genet., 27, 175, 10.1111/j.1469-1809.1963.tb00210.x Tang, 2001, Mapping quantitative trait loci in oligogenic models, Biostatistics, 2, 147, 10.1093/biostatistics/2.2.147 Whittemore, 2001, Problems in the definition, interpretation, and evaluation of genetic heterogeneity, Amer. J. Hum. Genet., 68, 457, 10.1086/318186