The Tumor Suppressor RASSF1A and MAP-1 Link Death Receptor Signaling to Bax Conformational Change and Cell Death

Adams, 2002, Apoptosomes: engines for caspase activation, Curr. Opin. Cell Biol., 14, 715, 10.1016/S0955-0674(02)00381-2 Boatright, 2003, A unified model for apical caspase activation, Mol. Cell, 11, 529, 10.1016/S1097-2765(03)00051-0 Bouillet, 2002, BH3-only proteins—evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death, J. Cell Sci., 115, 1567, 10.1242/jcs.115.8.1567 Brummelkamp, 2002, A system for stable expression of short interfering RNAs in mammalian cells, Science, 296, 550, 10.1126/science.1068999 Cain, 2002, The Apaf-1 apoptosome: a large caspase-activating complex, Biochimie, 84, 203, 10.1016/S0300-9084(02)01376-7 Chao, 1998, BCL-2 family: regulators of cell death, Annu. Rev. Immunol., 16, 395, 10.1146/annurev.immunol.16.1.395 Cox, 2003, The dark side of Ras: regulation of apoptosis, Oncogene, 22, 8999, 10.1038/sj.onc.1207111 Dammann, 2000, Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3, Nat. Genet., 25, 315, 10.1038/77083 Dammann, 2003, Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis, Histol. Histopathol., 18, 665 Dammann, 2005, The tumor suppressor RASSF1A in human carcinogenesis: an update, Histol. Histopathol., 20, 645 Danial, 2004, Cell death: critical control points, Cell, 116, 205, 10.1016/S0092-8674(04)00046-7 Degenhardt, 2002, Bax and Bak independently promote cytochrome C release from mitochondria, J. Biol. Chem., 277, 14127, 10.1074/jbc.M109939200 Degterev, 2003, A decade of caspases, Oncogene, 22, 8543, 10.1038/sj.onc.1207107 Denecker, 2001, Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria, Cell Death Differ., 8, 829, 10.1038/sj.cdd.4400883 Esposti, 2003, Mitochondrial membrane permeabilisation by Bax/Bak, Biochem. Biophys. Res. Commun., 304, 455, 10.1016/S0006-291X(03)00617-X Evan, 1995, Apoptosis and the cell cycle, Curr. Opin. Cell Biol., 7, 825, 10.1016/0955-0674(95)80066-2 Gogvadze, 2001, Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax, J. Biol. Chem., 276, 19066, 10.1074/jbc.M100614200 Harper, 2003, Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis, J. Biol. Chem., 278, 25534, 10.1074/jbc.M303399200 Ho, 2004, Splitting the apoptosome, Cell Cycle, 3, 446, 10.4161/cc.3.4.818 Ivanov, 2003, Death receptors and melanoma resistance to apoptosis, Oncogene, 22, 3152, 10.1038/sj.onc.1206456 Kandasamy, 2003, Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release, Cancer Res., 63, 1712 Kroemer, 2003, Mitochondrial control of apoptosis: an introduction, Biochem. Biophys. Res. Commun., 304, 433, 10.1016/S0006-291X(03)00614-4 Kuwana, 2002, Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane, Cell, 111, 331, 10.1016/S0092-8674(02)01036-X Letai, 2002, Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics, Cancer Cell, 2, 183, 10.1016/S1535-6108(02)00127-7 Liu, 2003, Control of microtubule stability by the RASSF1A tumor suppressor, Oncogene, 22, 8125, 10.1038/sj.onc.1206984 Micheau, 2003, Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes, Cell, 114, 181, 10.1016/S0092-8674(03)00521-X Mikhailov, 2003, Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release, J. Biol. Chem., 278, 5367, 10.1074/jbc.M203392200 Riedl, 2004, Molecular mechanisms of caspase regulation during apoptosis, Nat. Rev. Mol. Cell Biol., 5, 897, 10.1038/nrm1496 Schneider-Brachert, 2004, Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles, Immunity, 21, 415, 10.1016/j.immuni.2004.08.017 Scorrano, 2003, Mechanisms of cytochrome c release by proapoptotic BCL-2 family members, Biochem. Biophys. Res. Commun., 304, 437, 10.1016/S0006-291X(03)00615-6 Shivakumar, 2002, The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation, Mol. Cell. Biol., 22, 4309, 10.1128/MCB.22.12.4309-4318.2002 Song, 2004, Control of APC-Cdc20 by the tumor suppressor RASSF1A, Cell Cycle, 3, 574, 10.4161/cc.3.5.887 Sundararajan, 2001, Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K, J. Biol. Chem., 276, 45120, 10.1074/jbc.M106386200 Tan, 2001, MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains, J. Biol. Chem., 276, 2802, 10.1074/jbc.M008955200 Thorburn, 2004, Death receptor-induced cell killing, Cell. Signal., 16, 139, 10.1016/j.cellsig.2003.08.007 Tommasi, 2005, Tumor susceptibility of Rassf1a knockout mice, Cancer Res., 65, 92, 10.1158/0008-5472.92.65.1 Vousden, 2002, Activation of the p53 tumor suppressor protein, Biochim. Biophys. Acta, 1602, 47 Yin, 1999, Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis, Nature, 400, 886, 10.1038/23730 Zhivotovsky, 1999, Caspases: their intracellular localization and translocation during apoptosis, Cell Death Differ., 6, 644, 10.1038/sj.cdd.4400536