The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

Cell Host & Microbe - Tập 15 Số 3 - Trang 382-392 - 2014
Dirk Gevers1, Subra Kugathasan2, Lee A. Denson3, Yoshiki Vázquez‐Baeza4, Will Van Treuren5, Boyu Ren6, Emma Schwager6, Dan Knights7,8, Se Jin Song5, Moran Yassour1, Xochitl C. Morgan6, Aleksandar D. Kostic1, Chengwei Luo1, Antonio González5, Daniel McDonald5, Yael Haberman3, Thomas D. Walters9, Susan S. Baker10, Joel R. Rosh11, Michael C. Stephens12, Melvin B. Heyman13, James Markowitz14, Robert N. Baldassano15, Anne M. Griffiths16, Francisco Sylvester17, David R. Mack18, Sandra Kim19, Wallace Crandall19, Jeffrey S. Hyams17, Curtis Huttenhower1,6, Rob Knight5,20,21, Ramnik J. Xavier1,22,23
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
2Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University, Atlanta, GA 30322, USA
3Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
4Department of Computer Science, University of Colorado, Boulder, CO 80309, USA
5BioFrontiers Institute, University of Colorado, Boulder, CO 80309, USA
6Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
7BioTechnology Institute, University of Minnesota, St. Paul, MN 55108, USA
8Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN 55108, USA
9Division of Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children, University of Toronto, Toronto, ON M5G 1X8, Canada
10Children’s Hospital of Buffalo, Buffalo, NY 14222, USA
11Goryeb Children’s Hospital, Morristown, NJ 07960, USA
12Mayo Clinic, Rochester, MN 55902, USA
13University of California, San Francisco, San Francisco, CA 94143 USA
14North Shore Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA
15Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
16Hospital for Sick Children, Toronto, ON M5G 1X8, Canada
17Connecticut Children's Medical Center, Hartford, CT 06106, USA
18Children's Hospital of Eastern Ontario, Ottawa, ON K1H 8L1, Canada
19Nationwide Children’s Hospital, Columbus, OH 43228, USA
20Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309 USA
21Howard Hughes Medical Institute, Boulder, CO 80309, USA
22Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
23Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA

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