The Somatic Genomic Landscape of Glioblastoma

Cell - Tập 155 Số 2 - Trang 462-477 - 2013
Cameron Brennan1, Roel G.W. Verhaak2, Aaron McKenna3, Benito Campos4, Houtan Noushmehr5, Sofie R. Salama6, Siyuan Zheng7, Debyani Chakravarty8, Zack Sanborn6, Samuel H. Berman8, Rameen Beroukhim9, Brady Bernard10, Chang‐Jiun Wu11, Giannicola Genovese11, Ilya Shmulevich10, Jill S. Barnholtz‐Sloan12, Lihua Zou3, Rahulsimham Vegesna7, Sachet A. Shukla13, Giovanni Ciriello14, W. K. Alfred Yung15, Wei Zhang16, Carrie Sougnez3, Tom Mikkelsen17, Kenneth Aldape16, Darell D. Bigner18, Erwin G. Van Meir19, Michael D. Prados20, Andrew E. Sloan21, Keith L. Black22, Jennifer Eschbacher23, Gaetano Finocchiaro24, William A. Friedman25, David W. Andrews26, Abhijit Guha27, Mary Iacocca28, Brian Patrick O’Neill29, Greg Foltz30, Jerome Myers31, Daniel J. Weisenberger32, Robert Penny33, Raju Kucherlapati34, Charles M. Perou35, D. Neil Hayes35, Richard A. Gibbs36, Marco A. Marra37, Gordon B. Mills38, Sı́lvia Beà3, Paul T. Spellman39, Richard K. Wilson40, Chris Sander14, John N. Weinstein7, Matthew Meyerson9, Stacey Gabriel3, Peter W. Laird32, David Haussler41, Gad Getz3, Lynda Chin42, Christopher C. Benz, Wendi Barrett, Quinn T. Ostrom, Yingli Wolinsky, Bikash Bose, Paul T. Boulos, Madgy Boulos, Jenn Brown23, Christine Czerinski, Matthew Eppley9, Thelma Kempista, Teresa Kitko, Yakov Koyfman, Brenda Rabeno, Pawan Rastogi, Michael C. Sugarman20, Patricia Swanson, Kennedy Yalamanchii, Ilana P. Otey, Yingchun Spring Liu, Yonghong Xiao, J. Todd Auman, Peng‐Chieh Chen, Angela Hadjipanayis, Eunjung Lee, Semin Lee, Peter J. Park, Jonathan G. Seidman, Lixing Yang, Steven Kalkanis, Laila Poisson, Aditya Raghunathan, Lisa Scarpace, Ryan Bressler, Andrea Eakin, Lisa Iype, Richard Kreisberg, Kalle Leinonen, Sheila M. Reynolds, Hector Rovira, Vésteinn Thórsson, Matti Annala, Joseph Paulauskis, Erin Curley, Martha Hatfield, David Mallery41, Scott Morris, Troy Shelton, Candace Shelton, Mark E. Sherman, Peggy Yena, Lucia Cuppini, Francesco DiMeco, Marica Eoli, Emanuela Maderna, Bianca Pollo, Marco Saini37, Saianand Balu, Katherine A. Hoadley, Ling Li25, C. Ryan Miller, Yan Shi8, Michael D. Topal, Junyuan Wu11, Gavin P. Dunn, Caterina Giannini, Bülent Arman Aksoy, Yevgeniy Antipin, Laetitia Borsu, Ethan Cerami, Jianjiong Gao, Benjamin Groß, Anders J. Skanderup, Marc Ladanyi37, Alex E. Lash, Yupu Liang, Boris Reva, Nikolaus Schultz, Ronglai Shen, Nicholas D. Socci, Agnès Viale, Martin L. Ferguson, Qing‐Rong Chen, John A. Demchok7, Laura A. L. Dillon, Kenna Shaw, Margi Sheth, Roy Tarnuzzer, Zhining Wang, Liming Yang, Tanja M. Davidsen, Mark S. Guyer, Bradley A. Ozenberger, Heidi J. Sofia, Julie Bergsten, John Eckman7, Jodi Harr, Christine Smith, Kelly J. Tucker, Cindy Winemiller, Leigh Anne Zach6, Julia Y. Ljubimova, Greg Eley30, Brenda Ayala, Mark A. Jensen, A Kahn, Todd Pihl, David Pot41, Yunhu Wan26, Nathan Hansen, Parvi Hothi, Biaoyang Lin, Nameeta Shah, Jae‐Geun Yoon, Ching C. Lau, Michael E. Berens20, Kristin Ardlie, Scott L. Carter, Andrew D. Cherniack, Mike Noble, Juok Cho, Kristian Cibulskis, Daniel DiCara32, Scott Frazer, Nils Gehlenborg, Jeff Gentry, David I. Heiman41, Jaegil Kim, Rui Jing, Michael S. Lawrence20, Pei Lin, Will Mallard25, Robert C. Onofrio, Gordon Saksena38, Steven E. Schumacher, Petar Stojanov, Barbara Tabak, Doug Voet, Hailei Zhang16, Nathan N. Dees, Jun Li25, Lucinda Fulton, Robert S. Fulton, Krishna-Latha Kanchi, Elaine R. Mardis, Stephen B. Baylin, Larry A. Harshyne, Mark L. Cohen, Karen Devine, Scott R. VandenBerg, Mitchel S. Berger32, Daniel Carlin32, Brian Craft29, Kyle Ellrott, Mary J. Goldman28, Theodore C. Goldstein, Mia Grifford, Xiaotu Ma9, Sam Ng19, Joshua M. Stuart, Teresa Swatloski, Peter Waltman32, Jing Zhu, Robin M. Foss, Barbara Frentzen, Raquel G. McTiernan, Anthony T. Yachnis, Yong Mao, Rehan Akbani, Oliver Bögler, Gregory N. Fuller, Wenbin Liu, Yuexin Liu, Yiling Lu, Alexei Protopopov, Xiaojia Ren1, Youting Sun, Jianhua Zhang16, Ken Chen16, Moiz S. Bootwalla, Phillip H. Lai32, Youjia Li, David J. Van Den Berg, David H. Gutmann41, Norman L. Lehman, Daniel J. Brat32, Jeffrey J. Olson, Gena M. Mastrogianakis, Narra S. Devi, Zhaobin Zhang16, Eric Lipp3, Roger E. McLendon
1Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, Department of Neurological Surgery, Weill Cornell Medical Center, New York, NY 10065, USA
2Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
3Cancer Program, The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA
4Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, 69120 Heidelberg, Germany
5Department of Genetics, Center for Integrative System Biology, Faculty of Medicine at Ribeirão Preto, University of São Paulo, 14049-900 Ribeirão Preto, São Paulo, Brazil; University of Southern California Epigenome Center, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
6Department of Biomolecular Engineering and Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA
7Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
8Human Oncology and Pathogenesis Program, Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
9Cancer Program, The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA
10Institute for Systems Biology, Seattle, WA 98109, USA
11Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
12Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
13Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115 USA
14Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA
15Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
16Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
17Departments of Neurology and Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USA
18DEPARTMENT OF PATHOLOGY, DUKE UNIVERSITY MEDICAL CENTER, DURHAM, NC 27710 USA
19Departments of Neurosurgery and Hematology and Medical Oncology, Winship Cancer Institute and School of Medicine, Emory University, Atlanta, GA 30322, USA
20Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143 USA
21Department of Neurosurgery, University Hospitals-Case Medical Center, Seidman Cancer Center, Cleveland, OH 44106, USA
22Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
23Department of Pathology, St. Joseph’s Hospital and Medical Center, Phoenix, AZ 85013, USA
24Istituto Neurologico Besta, Department of Neuro-Oncology, 20133 Milano, Italy
25Department of Neurosurgery, University of Florida, Gainesville, FL 32610, USA
26Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, 19107, USA
27Department of Neurosurgery, Toronto Western Hospital, Toronto, ON M5T 2S8, Canada
28Department of Pathology, Christiana Care, Helen F. Graham Cancer Center, Newark, DE 19713, USA
29Department of Neurology, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, USA
30Ivy Brain Tumor Center, Swedish Neuroscience Institute, Seattle, WA 98122, USA
31Department of Pathology, Penrose-St. Francis Health Services, Colorado Springs, CO 80907, USA
32University of Southern California Epigenome Center, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
33International Genomics Consortium, Phoenix, AZ 85004, USA
34Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215, USA
35Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
36Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
37Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada
38Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
39Oregon Health and Science University, Department of Molecular and Medical Genetics, Portland, OR 97239, USA
40The Genome Institute, Washington University, St. Louis, MO 63110, USA
41Department of Biomolecular Engineering and Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA; Howard Hughes Medical Institute, University of California at Santa Cruz, Santa Cruz, CA 95064, USA
42Cancer Program, The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA

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Cell

Tập 155 Số 2

462-477

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