The SUUR protein is involved in binding of SU(VAR)3–9 and methylation of H3K9 and H3K27 in chromosomes of Drosophila melanogaster

Andreyeva EN, Kolesnikova TD, Demakova OV et al (2007) High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3–9 double mutants. Proc Natl Acad Sci USA 104:12819–12824 Bannister AJ, Zegerman P, Partridge JF et al (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromodomain. Nature 410:120–124 Belyaeva ES, Zhimulev IF, Volkova EI et al (1998) Su(UR)ES: a gene suppressing DNA underreplication in intercalary and pericentric heterochromatin of Drosophila melanogaster polytene chromosomes. Proc Natl Acad Sci USA 95:7532–7537 Belyaeva ES, Boldyreva LV, Volkova EI et al (2003) Effect of the Suppressor of Underreplication (SuUR) gene on position-effect variegation silencing in Drosophila melanogaster. Genetics 165:1209–1220 Brower-Toland B, Riddle NC, Jiang H et al (2009) Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster. Genetics 181:1303–1319 Carrington EA, Jones RS (1996) The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild type and mutant protein distribution. Development 122:4073–4083 Clough E, Moon W, Wang S et al (2007) Histone methylation is required for oogenesis in Drosophila. Development 134:157–165 Czermin B, Schotta G, Hülsmann BB et al (2001) Physical and functional association of SU(VAR)3–9 and HDAC1 in Drosophila. EMBO Rep 2:915–919 Czermin B, Melfi R, McCabe D et al (2002) Drosophila Enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111:185–196 de Napoles M, Mermoud JE, Wakao R et al (2004) Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell 7:663–676 Demakova OV, Pokholkova GV, Kolesnikova TD et al (2007) The SU(VAR)3–9/HP1 complex differentially regulates the compaction state and degree of underreplication of X chromosome pericentric heterochromatin in Drosophila melanogaster. Genetics 175:609–620 Dillon N, Festenstein R (2002) Unravelling heterochromatin: competition between positive and negative factors regulates accessibility. Trends Genet 18:252–258 Ebert A, Schotta G, Lein S et al (2004) Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev 18:2973–2983 Eskeland R, Eberharter A, Imhof A (2007) HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factors. Mol Cell Biol 27:453–465 Filion GJ, van Bemme JG, Braunschweig U et al (2010) Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Cell 143:212–224 Fischle W, Wang Y, Jacobs SA et al (2003) Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev 17:1870–1881 Jacobs SA, Taverna SD, Zhang Y et al (2001) Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. EMBO J 20:5232–5241 Koryakov DE, Reuter G, Dimitri P, Zhimulev IF (2006) The SuUR gene influences the distribution of heterochromatic proteins HP1 and SU(VAR)3–9 on nurse cell polytene chromosomes of Drosophila melanogaster. Chromosoma 115:296–310 Lachner M, O’Carroll D, Rea S et al (2001) Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116–120 Makunin IV, Volkova EI, Belyaeva ES et al (2002) The Drosophila Suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes. Genetics 160:1023–1034 Nielsen PR, Nietlispach D, Mott HR et al (2002) Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature 416:103–107 Pindyurin AV, Moorman C, de Wit E et al (2007) SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila. J Cell Sci 120:2344–2351 Pindyurin AV, Boldyreva LV, Shloma VV et al (2008) Interaction between the Drosophila heterochromatin proteins SUUR and HP1. J Cell Sci 121:1693–1703 Richards EJ, Elgin SCR (2002) Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell 108:489–500 Rudolph T, Yonezawa M, Lein S et al (2007) Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3–3. Mol Cell 26:103–115 Schotta G, Reuter G (2000) Controlled expression of tagged proteins in Drosophila using a new modular P-element vector system. Mol Gen Genet 262:916–920 Schotta G, Ebert A, Krauss V et al (2002) Central role of Drosophila SU(VAR)3–9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J 21:1121–1131 Schotta G, Lachner M, Sarma K et al (2004) A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18:1251–1262 Seum C, Reo E, Peng H et al (2007) Drosophila SETDB1 is required for chromosome 4 silencing. PLoS Genet 3(5):e76. doi:10.1371/journal.pgen.0030076 Stabell M, Eskeland R, Bjørkmo M et al (2006) The Drosophila G9a gene encodes a multi-catalytic histone methyltransferase required for normal development. Nucl Acids Res 34:4609–4621 Tschiersch B, Hofmann A, Krauss V et al (1994) The protein encoded by the Drosophila position effect variegation suppressor gene Su(var)3–9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J 13:3822–3831 Tzeng T, Lee C, Chan L, Shen C (2007) Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1. Proc Natl Acad Sci USA 104:12691–12696 Volkova EI, Yurlova AA, Kolesnikova TD et al (2003) Ectopic expression of the Suppressor of Underreplication gene inhibits endocycles but not the mitotic cell cycle in Drosophila melanogaster. Mol Gen Genomics 270:387–393 Wang H, Wang L, Erdjument-Bromage H et al (2004) Role of histone H2A ubiquitination in Polycomb silencing. Nature 431:873–878 Yoon J, Lee K, Park J et al (2008) dSETDB1 and SU(VAR)3–9 sequentially function during germline-stem cell differentiation in Drosophila melanogaster. PLoS ONE 3(5):e2234 Zhimulev IF, Belyaeva ES (2003) Intercalary heterochromatin and genetic silencing. BioEssays 25:1040–1051 Zhimulev IF, Belyaeva ES, Makunin IV et al (2003) Influence of the SuUR gene on intercalary heterochromatin in Drosophila melanogaster polytene chromosomes. Chromosoma 111:377–398