The Role of Tubule-Interstitial Crosstalk in Renal Injury and Recovery
Tóm tắt
Từ khóa
Tài liệu tham khảo
Lieberthal, 1998, Acute renal failure. I. Relative importance of proximal vs. distal tubular injury, Am J Physiol, 275, F623
Mahadevappa, 2014, Megalin in acute kidney injury: foe and friend, Am J Physiol Renal Physiol, 306, F147, 10.1152/ajprenal.00378.2013
Kramann, 2015, Who regenerates the kidney tubule?, Nephrol Dial Transplant, 30, 903, 10.1093/ndt/gfu281
Tan, 2016, Signaling crosstalk between tubular epithelial cells and interstitial fibroblasts after kidney injury, Kidney Dis, 2, 136, 10.1159/000446336
Grgic, 2012, Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis, Kidney Int, 82, 172, 10.1038/ki.2012.20
Kusaba, 2014, Differentiated kidney epithelial cells repair injured proximal tubule, Proc Natl Acad Sci U S A, 111, 1527, 10.1073/pnas.1310653110
Schiessl, 2018, Renal interstitial platelet-derived growth factor receptor-beta cells support proximal tubular regeneration, J Am Soc Nephrol, 29, 1383, 10.1681/ASN.2017101069
Berger, 2014, Origin of regenerating tubular cells after acute kidney injury, Proc Natl Acad Sci U S A, 111, 1533, 10.1073/pnas.1316177111
Angelotti, 2012, Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury, Stem Cells, 30, 1714, 10.1002/stem.1130
Humphreys, 2008, Intrinsic epithelial cells repair the kidney after injury, Cell Stem Cell, 2, 284, 10.1016/j.stem.2008.01.014
Rinkevich, 2014, In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration, Cell Rep, 7, 1270, 10.1016/j.celrep.2014.04.018
Lindgren, 2011, Isolation and characterization of progenitor-like cells from human renal proximal tubules, Am J Pathol, 178, 828, 10.1016/j.ajpath.2010.10.026
Smeets, 2013, Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration, J Pathol, 229, 645, 10.1002/path.4125
Moll, 1991, Expression of intermediate filament proteins in fetal and adult human kidney: modulations of intermediate filament patterns during development and in damaged tissue, Lab Invest, 65, 74
Veis, 1993, Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair, Cell, 75, 229, 10.1016/0092-8674(93)80065-M
Kumar, 2018, Cellular and molecular pathways of renal repair after acute kidney injury, Kidney Int, 93, 27, 10.1016/j.kint.2017.07.030
Sagrinati, 2006, Isolation and characterization of multipotent progenitor cells from the Bowmanapos's capsule of adult human kidneys, J Am Soc Nephrol, 10.1681/ASN.2006010089
Chang-Panesso, 2019, Foxm1 drives proximal tubule proliferation during repair from acute kidney injury, J Clin Invest, 10.1172/JCI125519
Kumar, 2015, Sox9 activation highlights a cellular pathway of renal repair in the acutely injured mammalian kidney, Cell Rep, 12, 1325, 10.1016/j.celrep.2015.07.034
Lazzeri, 2018, Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury, Nat Commun, 9, 1344, 10.1038/s41467-018-03753-4
Kang, 2016, Sox9-positive progenitor cells play a key role in renal tubule epithelial regeneration in mice, Cell Rep, 14, 861, 10.1016/j.celrep.2015.12.071
Appel, 2009, Recruitment of podocytes from glomerular parietal epithelial cells, J Am Soc Nephrol, 20, 333, 10.1681/ASN.2008070795
Berger, 2014, Mechanisms of epithelial repair and regeneration after acute kidney injury, Semin Nephrol, 34, 394, 10.1016/j.semnephrol.2014.06.006
Zou, 2018, Renal scattered tubular-like cells confer protective effects in the stenotic murine kidney mediated by release of extracellular vesicles, Sci Rep, 8, 1263, 10.1038/s41598-018-19750-y
Edgar, 2014, Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth, Nat Rev Mol Cell Biol, 15, 197, 10.1038/nrm3756
Kellum, 2016, Cell-cycle arrest and acute kidney injury: the light and the dark sides, Nephrol Dial Transplant, 31, 16, 10.1093/ndt/gfv130
Nielsen, 1998, Characterization of a kidney proximal tubule cell line, LLC-PK1, expressing endocytotic active megalin, J Am Soc Nephrol, 9, 1767, 10.1681/ASN.V9101767
Marable, 2018, Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome, JCI Insight, 3, 10.1172/jci.insight.97497
Schutgens, 2017, Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney, Proc Natl Acad Sci U S A, 114, E11190, 10.1073/pnas.1714145115
Laoukili, 2005, FoxM1 is required for execution of the mitotic programme and chromosome stability, Nat Cell Biol, 7, 126, 10.1038/ncb1217
Wierstra, 2013, The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological roles, Adv Cancer Res, 118, 97, 10.1016/B978-0-12-407173-5.00004-2
Genovese, 2014, The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?, Fibrogenesis Tissue Repair, 7, 4, 10.1186/1755-1536-7-4
Nath, 1992, Tubulointerstitial changes as a major determinant in the progression of renal damage, Am J Kidney Dis, 20, 1, 10.1016/S0272-6386(12)80312-X
Humphreys, 2018, Mechanisms of renal fibrosis, Annu Rev Physiol, 80, 309, 10.1146/annurev-physiol-022516-034227
Kramann, 2015, Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis, Cell Stem Cell, 16, 51, 10.1016/j.stem.2014.11.004
Humphreys, 2010, Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis, Am J Pathol, 176, 85, 10.2353/ajpath.2010.090517
Zeisberg, 2008, Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition, J Am Soc Nephrol, 19, 2282, 10.1681/ASN.2008050513
Zeisberg, 2009, Biomarkers for epithelial-mesenchymal transitions, J Clin Invest, 119, 1429, 10.1172/JCI36183
Zeisberg, 2008, Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis, Front Biosci, 13, 6991, 10.2741/3204
Reich, 2013, Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model, Kidney Int, 84, 78, 10.1038/ki.2013.84
Buchtler, 2018, Cellular origin and functional relevance of collagen I production in the kidney, J Am Soc Nephrol, 29, 1859, 10.1681/ASN.2018020138
Inoue, 2015, The contribution of epithelial-mesenchymal transition to renal fibrosis differs among kidney disease models, Kidney Int, 87, 233, 10.1038/ki.2014.235
Galichon, 2011, Epithelial to mesenchymal transition as a biomarker in renal fibrosis: are we ready for the bedside?, Fibrogenesis Tissue Repair, 4, 11, 10.1186/1755-1536-4-11
Zeisberg, 2010, Mechanisms of tubulointerstitial fibrosis, J Am Soc Nephrol, 21, 1819, 10.1681/ASN.2010080793
Zeisberg, 2010, Resolved: EMT produces fibroblasts in the kidney, J Am Soc Nephrol, 21, 1247, 10.1681/ASN.2010060616
Loeffler, 2015, Epithelial-to-mesenchymal transition in diabetic nephropathy: fact or fiction?, Cells, 4, 631, 10.3390/cells4040631
Endo, 2015, Exploring the origin and limitations of kidney regeneration, J Pathol, 236, 251, 10.1002/path.4514
Koesters, 2010, Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells, Am J Pathol, 177, 632, 10.2353/ajpath.2010.091012
Xu, 2015, The role of CD44 in epithelial-mesenchymal transition and cancer development, Onco Targets Ther, 8, 3783
Rampanelli, 2014, Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy, Kidney Int, 86, 558, 10.1038/ki.2014.87
Humphreys, 2013, Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis, J Clin Invest, 123, 4023, 10.1172/JCI45361
Zhou, 2017, The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer, Mol Cancer, 16, 52, 10.1186/s12943-017-0624-9
Overstreet, 2017, Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis, FASEB J, 31, 4407, 10.1096/fj.201601359RR
Qi, 2018, Renal tubular epithelial cells: the neglected mediator of tubulointerstitial fibrosis after injury, Cell Death Dis, 9, 1126, 10.1038/s41419-018-1157-x
Maarouf, 2016, Paracrine Wnt1 drives interstitial fibrosis without inflammation by tubulointerstitial cross-talk, J Am Soc Nephrol, 27, 781, 10.1681/ASN.2014121188
Grande, 2015, Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease, Nat Med, 21, 989, 10.1038/nm.3901
Monkawa, 2002, The hypertrophic effect of transforming growth factor-beta is reduced in the absence of cyclin-dependent kinase-inhibitors p21 and p27, J Am Soc Nephrol, 13, 1172, 10.1097/01.ASN.0000013162.29833.45
Rouschop, 2004, CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy, J Am Soc Nephrol, 15, 674, 10.1097/01.ASN.0000115703.30835.96
Ding, 2012, Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis, J Am Soc Nephrol, 23, 801, 10.1681/ASN.2011060614
Fabian, 2012, Hedgehog-Gli pathway activation during kidney fibrosis, Am J Pathol, 180, 1441, 10.1016/j.ajpath.2011.12.039
Kramann, 2015, Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis, J Clin Invest, 125, 2935, 10.1172/JCI74929
De Chiara, 2019, Tubule repair: with a little help from my "unexpected" friends, Kidney Int, 95, 487, 10.1016/j.kint.2018.11.019
Mack, 2015, Origin of myofibroblasts and cellular events triggering fibrosis, Kidney Int, 87, 297, 10.1038/ki.2014.287
Allinovi, 2018, Anti-fibrotic treatments: a review of clinical evidence, Matrix Biol, 68-69, 333, 10.1016/j.matbio.2018.02.017
Kaissling, 2013, Renal epithelial injury and fibrosis, Biochim Biophys Acta, 1832, 931, 10.1016/j.bbadis.2013.02.010
Fujigaki, 2005, Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acute renal failure in rats, Virchows Arch, 446, 164, 10.1007/s00428-004-1155-5
Kriz, 2005, Pathways to nephron loss starting from glomerular diseases-insights from animal models, Kidney Int, 67, 404, 10.1111/j.1523-1755.2005.67097.x
Sun, 2000, Possible involvement of myofibroblasts in cellular recovery of uranyl acetate-induced acute renal failure in rats, Am J Pathol, 157, 1321, 10.1016/S0002-9440(10)64647-0
Wolgast, 1981, Functional characteristics of the renal interstitium, Am J Physiol, 241, F105
Kaissling, 2008, The renal cortical interstitium: morphological and functional aspects, Histochem Cell Biol, 130, 247, 10.1007/s00418-008-0452-5
Schiessl, 2016, Just look! Intravital microscopy as the best means to study kidney cell death dynamics, Semin Nephrol, 36, 220, 10.1016/j.semnephrol.2016.03.009
Schiessl, 2019, Long-term cell fate tracking of individual renal cells using serial intravital microscopy, Methods Mol Biol, 10.1007/7651_2019_232
Peti-Peterdi, 2012, The first decade of using multiphoton microscopy for high-power kidney imaging, Am J Physiol Renal Physiol, 302, F227, 10.1152/ajprenal.00561.2011
Schiessl, 2016, Deep insights: intravital imaging with two-photon microscopy, Pflugers Arch, 468, 1505, 10.1007/s00424-016-1832-7
Shroff, 2019, Novel fluorescence techniques to quantitate renal cell biology, Methods Cell Biol, 154, 85, 10.1016/bs.mcb.2019.04.013
Ritsma, 2013, Steller EJ, Ellenbroek SI, Kranenburg O, Borel Rinkes IH, van Rheenen J. Surgical implantation of an abdominal imaging window for intravital microscopy, Nat Protoc, 8, 583, 10.1038/nprot.2013.026
Hackl, 2013, Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags, Nat Med, 19, 1661, 10.1038/nm.3405
Witzgall, 1994, Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells, J Clin Invest, 93, 2175, 10.1172/JCI117214
Duffield, 2005, Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury, Kidney Int, 68, 1956, 10.1111/j.1523-1755.2005.00629.x
Boor, 2014, PDGF and the progression of renal disease, Nephrol Dial Transplant, 29, i45, 10.1093/ndt/gft273
LeBleu, 2011, Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis, Kidney Int, 80, 1119, 10.1038/ki.2011.300
Chen, 2011, Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis, Kidney Int, 80, 1170, 10.1038/ki.2011.208
Nakagawa, 1999, Role of PDGF B-chain and PDGF receptors in rat tubular regeneration after acute injury, Am J Pathol, 155, 1689, 10.1016/S0002-9440(10)65484-3
Zhou, 2018, Fibroblast-specific beta-catenin signaling dictates the outcome of AKI, J Am Soc Nephrol, 29, 1257, 10.1681/ASN.2017080903
Clevers, 2006, Wnt/beta-catenin signaling in development and disease, Cell, 127, 469, 10.1016/j.cell.2006.10.018
Zhou, 2012, Tubule-specific ablation of endogenous beta-catenin aggravates acute kidney injury in mice, Kidney Int, 82, 537, 10.1038/ki.2012.173
Shi, 2018, Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a "U-shaped" relationship, Am J Physiol Renal Physiol, 314, F501, 10.1152/ajprenal.00306.2017
Sharples, 2004, Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion, J Am Soc Nephrol, 15, 2115, 10.1097/01.ASN.0000135059.67385.5D
Gerl, 2016, Erythropoietin production by PDGFR-beta(+) cells, Pflugers Arch, 468, 1479, 10.1007/s00424-016-1829-2
Yamauchi, 1999, A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice, Dev Biol, 212, 191, 10.1006/dbio.1999.9323
Nakamura, 2019, Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury, Kidney Int, 95, 526, 10.1016/j.kint.2018.10.017
El Kares, 2010, A human ALDH1A2 gene variant is associated with increased newborn kidney size and serum retinoic acid, Kidney Int, 78, 96, 10.1038/ki.2010.101
Batourina, 2001, Vitamin A controls epithelial/mesenchymal interactions through Ret expression, Nat Genet, 27, 74, 10.1038/83792
Lazzeri, 2014, Retinoids and glomerular regeneration, Semin Nephrol, 34, 429, 10.1016/j.semnephrol.2014.06.009
Darby, 2014, Fibroblasts and myofibroblasts in wound healing, Clin Cosmet Investig Dermatol, 7, 301
Desmouliere, 1995, Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar, Am J Pathol, 146, 56
Kuroyanagi, 2001, Tissue-engineered product: allogeneic cultured dermal substitute composed of spongy collagen with fibroblasts, Artif Organs, 25, 180, 10.1046/j.1525-1594.2001.025003180.x
Blumbach, 2010, Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFbeta1 levels and RhoA activity, J Cell Sci, 123, 3872, 10.1242/jcs.063024
Wang, 2004, Stimulation of skin repair is dependent on fibroblast source and presence of extracellular matrix, Tissue Eng, 10, 1054, 10.1089/ten.2004.10.1054
Kubo, 2005, A study of cytokines released from fibroblasts in cultured dermal substitute, Artif Organs, 29, 845, 10.1111/j.1525-1594.2005.00138.x
Nakamura, 2010, The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine, Proc Jpn Acad Ser B Phys Biol Sci, 86, 588, 10.2183/pjab.86.588
Miyagi, 2018, The role of hepatocyte growth factor in corneal wound healing, Exp Eye Res, 166, 49, 10.1016/j.exer.2017.10.006
Stoker, 1989, Effect of scatter factor on motility of epithelial cells and fibroblasts, J Cell Physiol, 139, 565, 10.1002/jcp.1041390316
Wysocki, 1993, Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9, J Invest Dermatol, 101, 64, 10.1111/1523-1747.ep12359590
Niiyama, 2014, Development of novel wound dressing composed of hyaluronic acid and collagen sponge containing epidermal growth factor and vitamin C derivative, J Artif Organs, 17, 81, 10.1007/s10047-013-0737-x
Dvorak, 1986, Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing, N Engl J Med, 315, 1650, 10.1056/NEJM198612253152606
Marx, 2008, Cancer biology. All in the stroma: cancer's Cosa Nostra, Science, 320, 38, 10.1126/science.320.5872.38
Huang, 2014, Cancer-associated fibroblasts in digestive tumors, World J Gastroenterol, 20, 17804, 10.3748/wjg.v20.i47.17804
Ramirez-Montagut, 2004, FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor, Oncogene, 23, 5435, 10.1038/sj.onc.1207730
Orimo, 2006, Stromal fibroblasts in cancer: a novel tumor-promoting cell type, Cell Cycle, 5, 1597, 10.4161/cc.5.15.3112
Okuda, 2008, Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer, Cancer Sci, 99, 2280, 10.1111/j.1349-7006.2008.00916.x
Chen, 2019, Turning foes to friends: targeting cancer-associated fibroblasts, Nat Rev Drug Discov, 18, 99, 10.1038/s41573-018-0004-1
Li, 2015, The cancer-associated fibroblasts and drug resistance, Eur Rev Med Pharmacol Sci, 19, 2112
Liu, 2019, Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy, J Hematol Oncol, 12, 86, 10.1186/s13045-019-0770-1
Lederle, 2006, Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells, Am J Pathol, 169, 1767, 10.2353/ajpath.2006.060120
Choe, 2013, Tumor-stromal interactions with direct cell contacts enhance motility of non-small cell lung cancer cells through the hedgehog signaling pathway, Anticancer Res, 33, 3715
Apostolopoulou, 2012, Cadherin-23 mediates heterotypic cell-cell adhesion between breast cancer epithelial cells and fibroblasts, PLoS One, 7, e33289, 10.1371/journal.pone.0033289
Hamed, 2011, Fibronectin potentiates topical erythropoietin-induced wound repair in diabetic mice, J Invest Dermatol, 131, 1365, 10.1038/jid.2011.15
Siebert, 2011, Erythropoietin improves skin wound healing and activates the TGF-beta signaling pathway, Lab Invest, 91, 1753, 10.1038/labinvest.2011.125
Jia, 2012, Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage, FASEB J, 26, 2847, 10.1096/fj.11-196618
Tankiewicz-Kwedlo, 2016, Erythropoietin accelerates tumor growth through increase of erythropoietin receptor (EpoR) as well as by the stimulation of angiogenesis in DLD-1 and Ht-29 xenografts, Mol Cell Biochem, 421, 1, 10.1007/s11010-016-2779-x
Debeljak, 2014, Erythropoietin and cancer: the unintended consequences of anemia correction, Front Immunol, 5, 563, 10.3389/fimmu.2014.00563
Zhou, 2014, Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal, J Clin Invest, 124, 553, 10.1172/JCI69804
Pierce, 1994, Tissue repair processes in healing chronic pressure ulcers treated with recombinant platelet-derived growth factor BB, Am J Pathol, 145, 1399