The Potentized Homeopathic Drug, Lycopodium clavatum (5C and 15C) Has Anti-cancer Effect on HeLa Cells In Vitro.

Kumar, 2007, 718 Frenkel, 2010, Homeopathy in cancer care, Altern Ther Health Med, 16, 12 House of Common Science and Technology Committee, 2010 Khuda-Bukhsh, 2003, Towards understanding molecular mechanism of action of homeopathic drugs: an overview, Mol Cell Biochem, 253, 339, 10.1023/A:1026048907739 Khuda-Bukhsh, 2006, Laboratory research in homeopathy, Pro Integr Cancer Ther, 5, 320, 10.1177/1534735406294794 Biswas, 2008, Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice, Food Chem Toxicol, 46, 1474, 10.1016/j.fct.2007.12.009 Pathak, 2006, Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azo dye induced hepatocarcinogenesis in mice, Mol Cell Biochem, 285, 121, 10.1007/s11010-005-9065-7 Paul, 2010, In vitro and in vivo studies demonstrate anticancer property of root extract of Polygala senega, J Acupunct Meridian Stud, 3, 188, 10.1016/S2005-2901(10)60035-0 Wang, 2000, Requirement for ERK activation in cisplatin-induced apoptosis, J Biol Chem, 275, 39435, 10.1074/jbc.M004583200 Samadder, 2012, Ameliorative potentials of Syzygium jambolanum extract against arsenic-induced stress in L6 cells in vitro, J Chin Integr Med, 10, 1293, 10.3736/jcim20121114 Mandal, 2010, Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation, Eur J Pharmacol, 626, 115, 10.1016/j.ejphar.2009.09.033 Paul, 2012, Chelidonine isolated from ethanolic extract of Chelidonium majus promotes apoptosis in HeLa cells through p38-p53 and PI3K/AKT signalling pathways, J Chin Integr Med, 10, 1025, 10.3736/jcim20120912 Das, 2013, Dihydroxy-isosteviol methyl ester isolated from Pulsatilla nigricans induces apoptosis in HeLa cells: its cytoxicity and interaction with calf thymus DNA as target, Phytother Res, 27, 664, 10.1002/ptr.4768 Samadder, 2011, Possible signaling cascades involved in attenuation of alloxan-induced oxidative stress and hyperglycemia in mice by ethanolic extract of Syzygium jambolanum: drug-DNA interaction with calf thymus DNA as target, Euro J Pharm Sci, 44, 207, 10.1016/j.ejps.2011.07.012 Banerjee, 2010, Chelidonium majus in 30C and 200C in induced hepatotoxicity in rats, Homeopathy, 99, 166, 10.1016/j.homp.2010.05.008 Bhattacharjee, 2012, Two homeopathic remedies used intermittently provide additional protective effects against hepatotoxicity induced by carcinogens in mice, J Acupunct Meridian Stud, 5, 166, 10.1016/j.jams.2012.05.004 Chen, 2008, Induction of apoptosis in human lung carcinoma A549 epithelial cells with an ethanol extract of Tremella mesenterica, Biosci Biotechnol Biochem, 72, 1283, 10.1271/bbb.70773 Das, 2012, Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria, Exp Biol Med (Maywood), 237, 1433, 10.1258/ebm.2012.012148 Enari, 1998, A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD, Nature, 391, 43, 10.1038/34112 Khuda-Bukhsh, 1997, Potentized homeopathic drugs act through regulation of gene expression: a hypothesis to explain their mechanism and pathways of action in vitro, Complement Ther Med, 59, 339 Khuda-Bukhsh, 2009, Mice as a model for homeopathy research, Homeopathy, 98, 267, 10.1016/j.homp.2009.09.007 Khuda-Bukhsh, 2011, Modulation of signal proteins: a plausible mechanism to explain how a potentized drug Secale cor 30C diluted beyond Avogadro's limit combat skin papilloma in mice, Evid Based Complement Alternat Med, 10.1093/ecam/nep084