The Origin of the “Ideal” Body Weight Equations

Annals of Pharmacotherapy - Tập 34 Số 9 - Trang 1066-1069 - 2000
Manjunath P. Pai1, Frank P. Paloucek2
1Manjunath P Pai PharmD, Infectious Diseases Fellow, Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL
2Frank P Paloucek PharmD ABAT, Clinical Associate Professor, Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago

Tóm tắt

OBJECTIVE: To provide a historical perspective on the origin and similarity of the “ideal” body weight (IBW) equations, and clarify the terms ideal and lean body weight (LBW). DATA SOURCES: Primary and review literature were identified using MEDLINE (1966–November 1999) and International Pharmaceutical Abstracts (1970–November 1999) pertaining to ideal and lean weight, height–weight tables, and obesity. In addition, textbooks and relevant reference lists were reviewed. DATA EXTRACTION: All articles identified through the data sources were evaluated. Information deemed to be relevant to the objectives of the review were included. DATA SYNTHESIS: Height–weight tables were generated to provide a means of comparing a population with respect to their relative weight. The weight data were found to correlate with mortality and resulted in the use of the terms desirable or ideal to describe these weights. Over the years, IBW was interpreted to represent a “fat-free” weight and thus was used as a surrogate for LBW. In addition, the pharmacokinetics of certain drugs were found to correlate with IBW and resulted in the use of IBW equations published by Devine. These equations were consistent with an old rule that was developed from height–weight tables to estimate IBW. Efforts to improve the IBW equations through regression analyses of height–weight data resulted in equations similar to those published by Devine. CONCLUSIONS: The similarity between the IBW equations was a result of the general agreement among the various height–weight tables from which they were derived. Therefore, any one of these equations may be used to estimate IBW.

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Tài liệu tham khảo

10.1177/106002807400801104

Robinson JD, 1983, Am J Hosp Pharm, 40, 1016

Miller DR, 1983, Am J Hosp Pharm, 40, 1622

10.1177/014860718000400302

10.1111/j.1753-4887.1991.tb02997.x

10.1111/j.1753-4887.1991.tb03013.x

10.1001/jama.1983.03340040046030

Harrison GG, 1985, Ann Intern Med, 103, 489

10.1080/00325481.1965.11695628

1942, Stat Bull, 23, 6

1943, Stat Bull, 24, 6

1959, Stat Bull, 40, 1

1983, Stat Bull, 64, 1

Hathaway ML, 1960, Heights and weights of adults in the United States, USDA

Overton MH, Lukert B P, eds. Clinical nutrition: a physiologic approach. Chicago: Year Book Medical Publishers, 1977:36.

10.1111/j.1753-4887.1961.tb01966.x

Williams SR. Nutrition and diet therapy. Saint Louis: The CV Mosby Company, 1973:483.

Ritschel WA, 1986, Methods Find Exp Clin Pharmacol, 8, 239

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Annals of Pharmacotherapy

Tập 34 Số 9

1066-1069

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