The Notch pathway in prostate development and cancer

Abate-Shen, 2000, Molecular genetics of prostate cancer, Genes Dev, 14, 2410, 10.1101/gad.819500

Abrahamsson, 1999, Neuroendocrine differentiation in prostatic carcinoma, Prostate, 39, 135, 10.1002/(SICI)1097-0045(19990501)39:2<135::AID-PROS9>3.0.CO;2-S

Alimirah, 2007, Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stress, Neoplasia, 9, 427, 10.1593/neo.07211

Artavanis-Tsakonas, 1995, Notch signaling, Science, 268, 225, 10.1126/science.7716513

Artavanis-Tsakonas, 1999, Notch signaling: cell fate control and signal integration in development, Science, 284, 770, 10.1126/science.284.5415.770

Axelson, 2004, The Notch signaling cascade in neuroblastoma: role of the basic helix-loop-helix proteins HASH-1 and HES-1, Cancer Lett, 204, 171, 10.1016/S0304-3835(03)00453-1

Bae, 2000, The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation, Development, 127, 2933, 10.1242/dev.127.13.2933

Belandia, 2005, Hey1, a mediator of notch signaling, is an androgen receptor corepressor, Mol Cell Biol, 25, 1425, 10.1128/MCB.25.4.1425-1436.2005

Berges, 1995, Implication of cell kinetic changes during the progression of human prostatic cancer, Clin Cancer Res, 1, 473

Berman, 2004, Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis, Dev Biol, 267, 387, 10.1016/j.ydbio.2003.11.018

Blaumueller, 1997, Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane, Cell, 90, 281, 10.1016/S0092-8674(00)80336-0

Brown, 2007, Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations, Prostate, 67, 1384, 10.1002/pros.20620

Callahan, 2004, Notch signaling in mammary development and oncogenesis, J Mammary Gland Biol Neoplasia, 9, 145, 10.1023/B:JOMG.0000037159.63644.81

Chen, 1997, Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression, Proc Natl Acad Sci USA, 94, 5355, 10.1073/pnas.94.10.5355

Chiba, 2006, Notch signaling in stem cell systems, Stem Cells, 24, 2437, 10.1634/stemcells.2005-0661

Cooper, 2003, Stromal factors involved in prostate carcinoma metastasis to bone, Cancer, 97, 739, 10.1002/cncr.11181

Cunha, 2002, Role of stroma in carcinogenesis of the prostate, Differentiation, 70, 473, 10.1046/j.1432-0436.2002.700902.x

Dalrymple, 2005, Role of notch-1 and E-cadherin in the differential response to calcium in culturing normal versus malignant prostate cells, Cancer Res, 65, 9269, 10.1158/0008-5472.CAN-04-3989

Donjacour, 2003, FGF-10 plays an essential role in the growth of the fetal prostate, Dev Biol, 261, 39, 10.1016/S0012-1606(03)00250-1

Dudjak, 1992, Cancer metastasis, Semin Oncol Nurs, 8, 40, 10.1016/0749-2081(92)90007-P

Edbauer, 2003, Reconstitution of gamma-secretase activity, Nat Cell Biol, 5, 486, 10.1038/ncb960

English, 1987, Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement, Prostate, 11, 229, 10.1002/pros.2990110304

Fleming, 1998, Structural conservation of Notch receptors and ligands, Semin Cell Dev Biol, 9, 599, 10.1006/scdb.1998.0260

Fraser, 2003, Contribution of functional voltage-gated Na+ channel expression to cell behaviors involved in the metastatic cascade in rat prostate cancer: I. Lateral motility, J Cell Physiol, 195, 479, 10.1002/jcp.10312

Freestone, 2003, Sonic hedgehog regulates prostatic growth and epithelial differentiation, Dev Biol, 264, 352, 10.1016/j.ydbio.2003.08.018

Gao, 1999, Suppression of the tumorigenicity of prostatic cancer cells by gene(s) located on human chromosome 19p13.1-13.2, Prostate, 38, 46, 10.1002/(SICI)1097-0045(19990101)38:1<46::AID-PROS6>3.0.CO;2-9

Garabedian, 1998, A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells, Proc Natl Acad Sci USA, 95, 15382, 10.1073/pnas.95.26.15382

Gelmann, 2002, Molecular biology of the androgen receptor, J Clin Oncol, 20, 3001, 10.1200/JCO.2002.10.018

Gingrich, 1997, Androgen-independent prostate cancer progression in the TRAMP model, Cancer Res, 57, 4687

Gipp, 2007, Hedgehog pathway activity in the LADY prostate tumor model, Mol Cancer, 6, 19, 10.1186/1476-4598-6-19

Goodell, 1996, Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo, J Exp Med, 183, 1797, 10.1084/jem.183.4.1797

Greenberg, 1995, Prostate cancer in a transgenic mouse, Proc Natl Acad Sci USA, 92, 3439, 10.1073/pnas.92.8.3439

Grishina, 2005, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling, Dev Biol, 288, 334, 10.1016/j.ydbio.2005.08.018

Gupta, 2007, Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells, Prostate, 68, 50, 10.1002/pros.20650

Hayward, 2004, Viral interactions with the Notch pathway, Semin Cancer Biol, 14, 387, 10.1016/j.semcancer.2004.04.018

Hayward, 1996, Normal development and carcinogenesis of the prostate. A unifying hypothesis, Ann NY Acad Sci, 784, 50, 10.1111/j.1749-6632.1996.tb16227.x

Hayward, 1995, Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1, In Vitro Cell Dev Biol Anim, 31, 14, 10.1007/BF02631333

Hayward, 1992, A functional model of adult human prostate epithelium. The role of androgens and stroma in architectural organisation and the maintenance of differentiated secretory function, J Cell Sci, 102, 361, 10.1242/jcs.102.2.361

He, 2006, Probing the functional link between androgen receptor coactivator and ligand-binding sites in prostate cancer and androgen insensitivity, J Biol Chem, 281, 6648, 10.1074/jbc.M511738200

Hu, 2002, Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice, J Biol Chem, 277, 44462, 10.1074/jbc.M205784200

Hu, 2004, RNA interference of achaete-scute homolog 1 in mouse prostate neuroendocrine cells reveals its gene targets and DNA binding sites, Proc Natl Acad Sci USA, 101, 5559, 10.1073/pnas.0306988101

Isaacs, 1987, Control of cell proliferation and cell death in the normal and neoplastic prostate, Vol. II, 85

Iso, 2003, HES and HERP families: multiple effectors of the Notch signaling pathway, J Cell Physiol, 194, 237, 10.1002/jcp.10208

Jenster, 1993, Nuclear import of the human androgen receptor, Biochem J, 293, 761, 10.1042/bj2930761

Jordan, 2006, Cancer stem cells, N Engl J Med, 355, 1253, 10.1056/NEJMra061808

Kasper, 1998, Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer, Lab Invest, 78, 319

Koutsilieris, 1993, Osteoblastic metastasis in advanced prostate cancer, Anticancer Res, 13, 443

Lai, 2004, Notch signaling: control of cell communication and cell fate, Development, 131, 965, 10.1242/dev.01074

Lamm, 2001, Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate, Dev Biol, 232, 301, 10.1006/dbio.2001.0187

LaTulippe, 2002, Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease, Cancer Res, 62, 4499

Lefort, 2007, Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases, Genes Dev, 21, 562, 10.1101/gad.1484707

Leo, 2000, The SRC family of nuclear receptor coactivators, Gene, 245, 1, 10.1016/S0378-1119(00)00024-X

Leong, 2006, Recent insights into the role of Notch signaling in tumorigenesis, Blood, 107, 2223, 10.1182/blood-2005-08-3329

Leong, 2007, Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin, J Exp Med, 204, 2935, 10.1084/jem.20071082

Lewis, 1998, Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear, Mech Dev, 78, 159, 10.1016/S0925-4773(98)00165-8

Li, 2007, Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo, Cancer Res, 67, 11244, 10.1158/0008-5472.CAN-07-0969

Litvinov, 2006, Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells, Cancer Res, 66, 8598, 10.1158/0008-5472.CAN-06-1228

Liu, 1997, Cell-cell interaction in prostate gene regulation and cytodifferentiation, Proc Natl Acad Sci USA, 94, 10705, 10.1073/pnas.94.20.10705

Marivoet, 1992, Interaction of the 90-kDa heat shock protein with native and in vitro translated androgen receptor and receptor fragments, Mol Cell Endocrinol, 88, 165, 10.1016/0303-7207(92)90021-W

Marker, 2003, Hormonal, cellular, and molecular control of prostatic development, Dev Biol, 253, 165, 10.1016/S0012-1606(02)00031-3

Martin, 2004, Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium, Cancer Res, 64, 347, 10.1158/0008-5472.CAN-03-2062

Masumori, 2001, A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential, Cancer Res, 61, 2239

McKenna, 1999, Nuclear receptor coregulators: cellular and molecular biology, Endocr Rev, 20, 321

McNeal, 1988, Normal histology of the prostate, Am J Surg Pathol, 12, 619, 10.1097/00000478-198808000-00003

Meek, 2004, The p53 response to DNA damage, DNA Repair (Amsterdam), 3, 1049, 10.1016/j.dnarep.2004.03.027

Milner, 1999, Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation, Blood, 93, 2431, 10.1182/blood.V93.8.2431

Mumm, 2000, Notch signaling: from the outside in, Dev Biol, 228, 151, 10.1006/dbio.2000.9960

Mungamuri, 2006, Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53, Cancer Res, 66, 4715, 10.1158/0008-5472.CAN-05-3830

Nair, 2003, Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway, J Virol, 77, 7106, 10.1128/JVI.77.12.7106-7112.2003

Nakano, 1999, Androgen-stimulated human prostate epithelial growth mediated by stromal-derived fibroblast growth factor-10, Endocr J, 46, 405, 10.1507/endocrj.46.405

Nantermet, 2004, Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland, J Biol Chem, 279, 1310, 10.1074/jbc.M310206200

Ohishi, 2003, Notch signalling in hematopoiesis, Semin Cell Dev Biol, 14, 143, 10.1016/S1084-9521(02)00183-0

Okano, 2005, Function of RNA-binding protein Musashi-1 in stem cells, Exp Cell Res, 306, 349, 10.1016/j.yexcr.2005.02.021

Patrawala, 2006, Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells, Oncogene, 25, 1696, 10.1038/sj.onc.1209327

Radtke, 1999, Deficient T cell fate specification in mice with an induced inactivation of Notch1, Immunity, 10, 547, 10.1016/S1074-7613(00)80054-0

Reiter, 1998, Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer, Proc Natl Acad Sci USA, 95, 1735, 10.1073/pnas.95.4.1735

Ren, 2007, Notch1 augments intracellular trafficking of adeno-associated virus type 2, J Virol, 81, 2069, 10.1128/JVI.01811-06

Salvati, 2005, Brain metastasis from prostate cancer. Report of 13 cases and critical analysis of the literature, J Exp Clin Cancer Res, 24, 203

Santagata, 2004, JAGGED1 expression is associated with prostate cancer metastasis and recurrence, Cancer Res, 64, 6854, 10.1158/0008-5472.CAN-04-2500

Scorey, 2006, Notch signalling and voltage-gated Na+ channel activity in human prostate cancer cells: independent modulation of in vitro motility, Prostate Cancer Prostatic Dis, 9, 399, 10.1038/sj.pcan.4500894

Shih Ie, 2007, Notch signaling, gamma-secretase inhibitors, and cancer therapy, Cancer Res, 67, 1879, 10.1158/0008-5472.CAN-06-3958

Shou, 2001, Dynamics of notch expression during murine prostate development and tumorigenesis, Cancer Res, 61, 7291

Small, 2001, Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype, J Biol Chem, 276, 32022, 10.1074/jbc.M100933200

Smalley, 2005, The mammary gland “side population”: a putative stem/progenitor cell marker?, J Mammary Gland Biol Neoplasia, 10, 37, 10.1007/s10911-005-2539-0

Steers, 2001, 5alpha-reductase activity in the prostate, Urology, 58, 17, 10.1016/S0090-4295(01)01299-7

Sugimura, 1986, Morphogenesis of ductal networks in the mouse prostate, Biol Reprod, 34, 961, 10.1095/biolreprod34.5.961

Swanson, 2006, Current status of lymph node-positive prostate cancer: Incidence and predictors of outcome, Cancer, 107, 439, 10.1002/cncr.22034

Tran, 2002, Prostate stem cell antigen is a marker of late intermediate prostate epithelial cells, Mol Cancer Res, 1, 113

van Bokhoven, 2003, Molecular characterization of human prostate carcinoma cell lines, Prostate, 57, 205, 10.1002/pros.10290

Van Den Berg, 1995, DNA sequence amplification in human prostate cancer identified by chromosome microdissection: potential prognostic implications, Clin Cancer Res, 1, 11

Velasco, 2004, Identification and validation of novel androgen-regulated genes in prostate cancer, Endocrinology, 145, 3913, 10.1210/en.2004-0311

Wang, 2003, Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells, J Biol Chem, 278, 18506, 10.1074/jbc.M300968200

Wang, 2000, Up a notch: instructing gliogenesis, Neuron, 27, 197, 10.1016/S0896-6273(00)00028-3

Wang, 2006, Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation, Dev Biol, 290, 66, 10.1016/j.ydbio.2005.11.009

Wang, 2004, Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement, J Biol Chem, 279, 24733, 10.1074/jbc.M401602200

Wang, 2001, Cell differentiation lineage in the prostate, Differentiation, 68, 270, 10.1046/j.1432-0436.2001.680414.x

Wei, 2006, A global map of p53 transcription-factor binding sites in the human genome, Cell, 124, 207, 10.1016/j.cell.2005.10.043

Weng, 2004, Multiple niches for Notch in cancer: context is everything, Curr Opin Genet Dev, 14, 48, 10.1016/j.gde.2003.11.004

Yang, 2005, Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1, Mol Biol Cell, 16, 927, 10.1091/mbc.E04-07-0614

Yoon, 2005, Notch signaling in the mammalian central nervous system: insights from mouse mutants, Nat Neurosci, 8, 709, 10.1038/nn1475

Yugawa, 2007, Regulation of Notch1 gene expression by p53 in epithelial cells, Mol Cell Biol, 27, 3732, 10.1128/MCB.02119-06

Zayzafoon, 2004, Notch signaling and ERK activation are important for the osteomimetic properties of prostate cancer bone metastatic cell lines, J Biol Chem, 279, 3662, 10.1074/jbc.M308158200

Zhang, 2006, Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells, Int J Cancer, 119, 2071, 10.1002/ijc.22077

Zheng, 2000, Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears, Nat Neurosci, 3, 580, 10.1038/75753

Zheng, 2000, Hes1 is a negative regulator of inner ear hair cell differentiation, Development, 127, 4551, 10.1242/dev.127.21.4551

Zhou, 1994, A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences, J Biol Chem, 269, 13115, 10.1016/S0021-9258(17)36806-0