The Human Plasma Proteome

Yudell, 2002

Putnam, 1975

Anderson, 1997, A comparison of selected mRNA and protein abundances in human liver, Electrophoresis., 18, 533, 10.1002/elps.1150180333

Kawamoto, 1996, Expression profiles of active genes in human and mouse livers, Gene (Amst.)., 174, 151, 10.1016/0378-1119(96)00512-4

Putnam, 1975, 1

Cohn, 1948, The history of plasma fractionation, Adv. Mil. Med., 1, 364

Schultze, 1966

Moss, 1999, 617

Skeggs, 2000, Persistence and prayer: from the artificial kidney to the AutoAnalyzer, Clin. Chem., 46, 1425, 10.1093/clinchem/46.9.1425

Anderson, 1969, Computer interfaced fast analyzers, Science., 166, 317, 10.1126/science.166.3903.317

Kohler, 1975, Continuous cultures of fused cells secreting antibody of predefined specificity, Nature., 256, 495, 10.1038/256495a0

Bast, 1983, A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer, N. Engl. J. Med., 309, 883, 10.1056/NEJM198310133091503

O’Brien, 2001, The CA 125 gene: an extracellular superstructure dominated by repeat sequences, Tumor Biol., 22, 348, 10.1159/000050638

Devine, 1994, Serum markers CASA and CA 15-3 in ovarian cancer: all MUC1 assays are not the same, Tumor Biol., 15, 337, 10.1159/000217910

Cheung, 2000, Tumour marker measurements in the diagnosis and monitoring of breast cancer, Cancer Treat. Rev., 26, 91, 10.1053/ctrv.1999.0151

Klose, 1975, Protein mapping by combined isoelectric focusing and electrophoresis of mouse tissues. A novel approach to testing for induced point mutations in mammals, Humangenetik., 26, 231, 10.1007/BF00281458

O’Farrell, 1975, High resolution two-dimensional electrophoresis of proteins, J. Biol. Chem., 250, 4007, 10.1016/S0021-9258(19)41496-8

Anderson, 1977, High resolution two-dimensional electrophoresis of human plasma proteins, Proc. Natl. Acad. Sci. U. S. A., 74, 5421, 10.1073/pnas.74.12.5421

Anderson, 1991, A two-dimensional gel database of human plasma proteins, Electrophoresis., 12, 883, 10.1002/elps.1150121108

Hughes, 1992, Plasma protein map: an update by microsequencing, Electrophoresis., 13, 707, 10.1002/elps.11501301150

Anderson, 1975, Analytical techniques for cell fractions. XIX. The cyclum: an automatic system for cyclic chromatography, Anal. Biochem., 66, 159, 10.1016/0003-2697(75)90734-4

Pieper, R., and Anderson, N. L. (Sept. 12, 2002) U. S. Patent Application 20020127739

Tracy, 1982, Two-dimensional gel electrophoresis of serum specimens from a normal population, Clin. Chem., 28, 890, 10.1093/clinchem/28.4.890

Harrison, 1991, Identification of a serum protein polymorphism via two-dimensional electrophoresis. Family and population studies in two genetically isolated groups: North American Hutterites and Australian aborigines, Am. J. Hum. Genet., 48, 362

Harrison, 1991, Biochemical and clinical characterization of prealbuminCHICAGO: an apparently benign variant of serum prealbumin (transthyretin) discovered with high-resolution two-dimensional electrophoresis, Am. J. Med. Genet., 39, 442, 10.1002/ajmg.1320390415

Rosenblum, 1983, Two-dimensional electrophoresis of plasma polypeptides reveals “high” heterozygosity indices, Proc. Natl. Acad. Sci. U. S. A., 80, 5002, 10.1073/pnas.80.16.5002

Anderson, 1979, Microheterogeneity of serum transferrin, haptoglobin and α 2 HS glycoprotein examined by high resolution two-dimensional electrophoresis, Biochem. Biophys. Res. Commun., 88, 258, 10.1016/0006-291X(79)91724-8

Anderson, 1992, Covalent protein modifications and gene expression changes in rodent liver following administration of methapyrilene: a study using two-dimensional electrophoresis, Fundam. Appl. Toxicol., 18, 570, 10.1016/0272-0590(92)90116-Y

Gravel, 1994, Analysis of glycoproteins separated by two-dimensional gel electrophoresis using lectin blotting revealed by chemiluminescence, Anal. Biochem., 221, 66, 10.1006/abio.1994.1380

Golaz, 1995, Rapid detection of the main human plasma glycoproteins by two-dimensional polyacrylamide gel electrophoresis lectin affinoblotting, Electrophoresis., 16, 1187, 10.1002/elps.11501601197

Gravel, 1996, New alterations of serum glycoproteins in alcoholic and cirrhotic patients revealed by high resolution two-dimensional gel electrophoresis, Biochem. Biophys. Res. Commun., 220, 78, 10.1006/bbrc.1996.0360

Harrison, 1992, Multiple serum protein abnormalities in carbohydrate-deficient glycoprotein syndrome: pathognomonic finding of two-dimensional electrophoresis?, Clin. Chem., 38, 1390, 10.1093/clinchem/38.7.1390a

Henry, 1997, Microheterogeneity of serum glycoproteins and their liver precursors in patients with carbohydrate-deficient glycoprotein syndrome type I: apparent deficiencies in clusterin and serum amyloid P, J. Lab. Clin. Med., 129, 412, 10.1016/S0022-2143(97)90074-3

Henry, 1999, Microheterogeneity of serum glycoproteins in patients with chronic alcohol abuse compared with carbohydrate-deficient glycoprotein syndrome type I, Clin. Chem., 45, 1408, 10.1093/clinchem/45.9.1408

Choukaife, 1989, Two-dimensional electrophoresis of plasma proteins and high density lipoproteins during inflammation, Electrophoresis., 10, 781, 10.1002/elps.1150101110

Saile, 1990, Variations in apolipoproteins serum amyloid A, A-I, A-II, and C-III in severely head-injured patients, J. Clin. Chem. Clin. Biochem., 28, 519

Bini, 1992, Two-dimensional electrophoresis analysis of human serum proteins during the acute-phase response, Electrophoresis., 13, 743, 10.1002/elps.11501301161

Bruun, 1998, A two-dimensional electrophoretic study of serum amyloid A and C-reactive protein in infants and children, Electrophoresis., 19, 776, 10.1002/elps.1150190529

Liberatori, 1997, Acute-phase proteins in perinatal human plasma, Electrophoresis., 18, 520, 10.1002/elps.1150180331

Bini, 1996, Two-dimensional electrophoretic patterns of acute-phase human serum proteins in the course of bacterial and viral diseases, Electrophoresis., 17, 612, 10.1002/elps.1150170333

Doherty, 1998, Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis, Electrophoresis., 19, 355, 10.1002/elps.1150190234

Tissot, 1991, High-resolution two-dimensional protein electrophoresis of pathological plasma/serum, Appl. Theor. Electrophor., 2, 7

Tissot, 1993, Plasma/serum protein patterns in human fetuses and infants: a study by high-resolution two-dimensional polyacrylamide gel electrophoresis, Appl. Theor. Electrophor., 3, 183

Magi, 1995, Two-dimensional electrophoresis of human serum proteins modified by ampicillin during therapeutic treatment, Electrophoresis., 16, 1190, 10.1002/elps.11501601198

Lonberg-Holm, 1986, Classification of malnutrition by statistical analysis of quantitative two-dimensional gel electrophoresis of plasma proteins, Comput. Biomed. Res., 19, 340, 10.1016/0010-4809(86)90047-9

John, 1989, Elevated plasma levels of haptoglobin in Duchenne muscular dystrophy: electrophoretic variants in patients with a severe form of the disease, Electrophoresis., 10, 489, 10.1002/elps.1150100707

Myrick, 1990, Identification of haptoglobin α-2FF variants in mid-trimester maternal serum as potential markers for Down syndrome, Appl. Theor. Electrophor., 1, 233

Del Priore, 1991, Comparison of mononuclear cell proteins and plasma proteins before and during parturition by two dimensional electrophoresis, J. Perinat. Med., 19, 373, 10.1515/jpme.1991.19.5.373

Larina, 1991, Protein composition in human plasma after long-term orbital missions and in rodent plasma after spaceflights on biosatellites “Cosmos-1887” and “Cosmos-2044.”, Physiologist., 34, S94

Burgess-Cassler, 1992, Two-dimensional gel analysis of serum apolipoprotein A-I isoforms: preliminary analysis suggests altered ratios in individuals with heart disease, Appl. Theor. Electrophor., 3, 41

Hoermann, 1993, Molecular heterogeneity of human chorionic gonadotropin in serum and urine from patients with trophoblastic tumors, Clin. Investig., 71, 953, 10.1007/BF00185610

Cameron, 1995, Preliminary study of an increase of a plasma apolipoprotein E variant associated with peripheral nerve damage. A finding in patients with chronic spinal pain, Spine., 20, 581, 10.1097/00007632-199503010-00014

Choi, 1924, Identification of oxidized plasma proteins in Alzheimer’s disease, Biochem. Biophys. Res. Commun., 293, 1566, 10.1016/S0006-291X(02)00420-5

Eberini, 1999, Proteins of rat serum IV. Time-course of acute-phase protein expression and its modulation by indomethacine, Electrophoresis., 20, 846, 10.1002/(SICI)1522-2683(19990101)20:4/5<846::AID-ELPS846>3.0.CO;2-2

Haynes, 1998, Proteins of rat serum: I. establishing a reference two-dimensional electrophoresis map by immunodetection and microbore high performance liquid chromatography-electrospray mass spectrometry, Electrophoresis., 19, 1484, 10.1002/elps.1150190845

Anderson, 1981, High resolution two-dimensional electrophoretic mapping of immunoglobulin light chains, Immunol. Lett., 2, 195, 10.1016/0165-2478(81)90041-9

Harrison, 1992, Patient-specific microheterogeneity patterns of monoclonal immunoglobulin light chains as revealed by high resolution, two-dimensional electrophoresis, Clin. Biochem., 25, 235, 10.1016/0009-9120(92)80027-E

Tracy, 1982, Two-dimensional gel electrophoresis of serum specimens from patients with monoclonal gammopathies, Clin. Chem., 28, 900, 10.1093/clinchem/28.4.900

Tracy, 1984, Two-dimensional gel electrophoresis as an aid in the analysis of monoclonal gammopathies, Hum. Pathol., 15, 122, 10.1016/S0046-8177(84)80051-9

Stulik, 1993, Two-dimensional gel electrophoresis of four serum samples from patients with IgD myeloma, Clin. Chim. Acta., 218, 149, 10.1016/0009-8981(93)90179-8

Vu, 2002, Electrophoretic characteristics of monoclonal immunoglobulin G of different subclasses, J. Chromatogr. B. Anal. Technol. Biomed. Life Sci., 771, 355, 10.1016/S0378-4347(01)00384-X

Tissot, 1992, Clonal imbalances of serum immunoglobulins after allogeneic bone marrow transplantation: an analysis by high-resolution two-dimensional gel electrophoresis, Bone Marrow Transplant., 10, 347

Tissot, 1993, Clonal imbalances of plasma/serum immunoglobulin production in infants, Electrophoresis., 14, 245, 10.1002/elps.1150140142

Zahnd, 1993, Wave packets analysis of two-dimensional protein maps: a new approach to study the diversity of immunoglobulins, Appl. Theor. Electrophor., 3, 321

Petricoin, 2002, Use of proteomic patterns in serum to identify ovarian cancer, Lancet., 359, 572, 10.1016/S0140-6736(02)07746-2

Washburn, 2001, Large-scale analysis of the yeast proteome by multidimensional protein identification technology, Nat. Biotechnol., 19, 242, 10.1038/85686

Lipton, 2002, Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags, Proc. Natl. Acad. Sci. U. S. A., 99, 11049, 10.1073/pnas.172170199

Davis, 2001, Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. II. Limitations of complex mixture analyses, Proteomics., 1, 108, 10.1002/1615-9861(200101)1:1<108::AID-PROT108>3.0.CO;2-5

Spahr, 2001, Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. I. Profiling an unfractionated tryptic digest, Proteomics., 1, 93, 10.1002/1615-9861(200101)1:1<93::AID-PROT93>3.0.CO;2-3

Adkins, J. N., Varnum, S. M., Auberry, K. J., Moore, R. J., Angell, N. H., Smith, R. D., Springer, D. I., and Pounds, J. G. (2002) Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry. Mol. Cell Proteomics, in press

MacCoss, 2002, Shotgun identification of protein modifications from protein complexes and lens tissue, Proc. Natl. Acad. Sci. U. S. A., 99, 7900, 10.1073/pnas.122231399

Wu, 2002, Targeted proteomics of low-level proteins in human plasma by LC/MS(n): using human growth hormone as a model system, J. Proteome Res., 1, 459, 10.1021/pr025537l

Schepky, 1994, Human hemofiltrate as a source of circulating bioactive peptides: determination of amino acids, peptides and proteins, Biomed. Chromatogr., 8, 90, 10.1002/bmc.1130080209

Richter, 1999, Composition of the peptide fraction in human blood plasma: database of circulating human peptides, J. Chromatogr. B Biomed. Sci. Appl., 726, 25, 10.1016/S0378-4347(99)00012-2

Desiderio, 1983, Preparation of stable isotope-incorporated peptide internal standards for field desorption mass spectrometry quantification of peptides in biologic tissue, Biomed. Mass Spectrom., 10, 471, 10.1002/bms.1200100806

Patterson, 1997, Measurement of very low stable isotope enrichments by gas chromatography/mass spectrometry: application to measurement of muscle protein synthesis, Metabolism., 46, 943, 10.1016/S0026-0495(97)90084-6

Yarasheski, 1992, Measurement of muscle protein fractional synthetic rate by capillary gas chromatography/combustion isotope ratio mass spectrometry, Biol. Mass Spectrom., 21, 486, 10.1002/bms.1200211004

Kulik, 1998, Determination of Δ13C values of valine in protein hydrolysate by gas chromatography-combustion isotope ratio mass spectrometry, J. Chromatogr. B Biomed. Sci. Appl., 710, 37, 10.1016/S0378-4347(98)00090-5

Zachwieja, 1994, Growth hormone administration in older adults: effects on albumin synthesis, Am. J. Physiol., 266, E840

Lahm, 2000, Mass spectrometry: a tool for the identification of proteins separated by gels, Electrophoresis., 21, 2105, 10.1002/1522-2683(20000601)21:11<2105::AID-ELPS2105>3.0.CO;2-M

Oda, 1999, Accurate quantitation of protein expression and site-specific phosphorylation, Proc. Natl. Acad. Sci. U. S. A., 96, 6591, 10.1073/pnas.96.12.6591

Ong, 2002, Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics, Mol. Cell Proteomics., 1, 376, 10.1074/mcp.M200025-MCP200

Gygi, 1999, Quantitative analysis of complex protein mixtures using isotope-coded affinity tags, Nat. Biotechnol., 17, 994, 10.1038/13690

Sechi, 2002, A method to identify and simultaneously determine the relative quantities of proteins isolated by gel electrophoresis, Rapid Commun. Mass Spectrom., 16, 1416, 10.1002/rcm.734

Niwayama, 2001, Synthesis of d-labeled N-alkylmaleimides and application to quantitative peptide analysis by isotope differential mass spectrometry, Bioorg. Med. Chem. Lett., 11, 2257, 10.1016/S0960-894X(01)00452-8

Ji, 2000, Strategy for qualitative and quantitative analysis in proteomics based on signature peptides, J. Chromatogr. B Biomed. Sci. Appl., 745, 197, 10.1016/S0378-4347(00)00192-4

Munchbach, 2000, Quantitation and facilitated de novo sequencing of proteins by isotopic N-terminal labeling of peptides with a fragmentation-directing moiety, Anal. Chem., 72, 4047, 10.1021/ac000265w

Goodlett, 2001, Differential stable isotope labeling of peptides for quantitation and de novo sequence derivation, Rapid Commun. Mass Spectrom., 15, 1214, 10.1002/rcm.362

Stewart, 2001, 18O labeling: a tool for proteomics, Rapid Commun. Mass Spectrom., 15, 2456, 10.1002/rcm.525

Yao, 2001, Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus, Anal. Chem., 73, 2836, 10.1021/ac001404c

Ekins, 1991, Multianalyte microspot immunoassay—microanalytical “compact disk” of the future, Clin. Chem., 37, 1955, 10.1093/clinchem/37.11.1955

Stoll, 2002, Protein microarray technology, Front. Biosci., 7, c13, 10.2741/stoll

Schweitzer, 2002, Multiplexed protein profiling on microarrays by rolling-circle amplification, Nat. Biotechnol., 20, 359, 10.1038/nbt0402-359

Cahill, 2001, Protein and antibody arrays and their medical applications, J. Immunol. Methods., 250, 81, 10.1016/S0022-1759(01)00325-8

James, 1988, Protein heterogeneity of lipoprotein particles containing apolipoprotein A-I without apolipoprotein A-II and apolipoprotein A-I with apolipoprotein A-II isolated from human plasma, J. Lipid Res., 29, 1557, 10.1016/S0022-2275(20)38408-X

Chan, 1994, Characterization of rat serum insulin-like growth factor-binding proteins by two-dimensional gel electrophoresis: identification of a potentially novel form, Endocrinology., 134, 2574, 10.1210/endo.134.6.7515003

Gavin, 2002, Functional organization of the yeast proteome by systematic analysis of protein complexes, Nature., 415, 141, 10.1038/415141a

Nedelkov, 2001, Delineation of in vivo assembled multiprotein complexes via biomolecular interaction analysis mass spectrometry, Proteomics., 1, 1441, 10.1002/1615-9861(200111)1:11<1441::AID-PROT1441>3.0.CO;2-X

Chen, Y., Luo, J., Yu, P., Gu, X., and Jiang, Y. (2002) in Workshop Poster Abstracts from the Human Genome Meeting, Shanghai, China, April 14–17, 2002, Genome Informatics and Annotation, Poster 10, hgm2002.hgu.mrc.ac.uk/Abstracts/

McFarlane, 2000

Sacher, 2000

Cloonan, 1979, An enzyme-immunoassay for myoglobin in human serum and urine. Method development, normal values and application to acute myocardial infarction, Pathology., 11, 689, 10.3109/00313027909059049

Walter, 1999, Enzymatic markers of reperfusion in acute myocardial infarct. With data from the ISAM study, Herz., 24, 430, 10.1007/BF03044429

Voss, 1995, Human and canine cardiac troponin T and creatine kinase-MB distribution in normal and diseased myocardium. Infarct sizing using serum profiles, Arch. Pathol. Lab. Med., 119, 799

Tietz, 1995, 488

Wodzig, 1997, Estimation of myocardial infarct size from plasma myoglobin or fatty acid-binding protein. Influence of renal function, Eur. J. Clin. Chem. Clin. Biochem., 35, 191

Bleifeld, 1977, Infarct size estimated from serial serum creatine phosphokinase in relation to left ventricular hemodynamics, Circulation., 55, 303, 10.1161/01.CIR.55.2.303

Abe, 1994, Early assessment of reperfusion therapy using cardiac troponin T, J. Am. Coll. Cardiol., 23, 1382, 10.1016/0735-1097(94)90381-6

Vogel, 1998, Accelerator mass spectrometry as a bioanalytical tool for nutritional research, Adv. Exp. Med. Biol., 445, 397, 10.1007/978-1-4899-1959-5_25

Burtis, 1999

Harris, 1974, Effects of intra- and interindividual variation on the appropriate use of normal ranges, Clin. Chem., 20, 1535, 10.1093/clinchem/20.12.1535

Harris, 1975, Some theory of reference values. I. Stratified (categorized) normal ranges and a method for following an individual’s clinical laboratory values, Clin. Chem., 21, 1457, 10.1093/clinchem/21.10.1457

Macy, 1997, Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications, Clin. Chem., 43, 52, 10.1093/clinchem/43.1.52

Zweig, 1993, Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine, Clin. Chem., 39, 561, 10.1093/clinchem/39.4.561

Lewis, 2001, Longitudinal stability of coagulation, fibrinolysis, and inflammation factors in stored plasma samples, Thromb. Haemostasis., 86, 1495, 10.1055/s-0037-1616754

Buckley, 1971, Serum immunoglobulin levels throughout the life-span of healthy man, Ann. Intern. Med., 75, 673, 10.7326/0003-4819-75-5-673

Buckley, 1971, Addendum: immunoglobulins and ethnic groups, Ann. Intern. Med., 75, 972, 10.7326/0003-4819-75-6-972_1

Milani-Comparetti, 1976, Plasma protein variability in MZ twins, Acta Genet. Med. Gemellol., 25, 154, 10.1017/S0001566000014033

Cava, 2000, Biological variation of interleukin 6 (IL-6) and soluble interleukin 2 receptor (sIL2R) in serum of healthy individuals, Cytokine., 12, 1423, 10.1006/cyto.2000.0714

Anesi, 2000, Biological variability of myoglobin in healthy elderly and younger subjects, Aging (Milano)., 12, 168

Tuxen, 1999, Assessment of biological variation and analytical imprecision of CA 125, CEA, and TPA in relation to monitoring of ovarian cancer, Gynecol. Oncol., 74, 12, 10.1006/gyno.1999.5414

Panteghini, 1993, Pre-analytical, analytical and biological sources of variation of lipoprotein(a), Eur. J. Clin. Chem. Clin. Biochem., 31, 23

Huguet, 1991, Biological variation in the catalytic concentration of pancreatic α-amylase and triacylglycerol lipase in serum, Scand. J. Clin. Lab. Investig., 51, 735, 10.3109/00365519109104588

Statland, 1974, Factors contributing to intra-individual variation of serum constituents: 4. effects of posture and tourniquet application on variation of serum constituents in healthy subjects, Clin. Chem., 20, 1513, 10.1093/clinchem/20.12.1513

Statland, 1973, Factors contributing to intra-individual variation of serum constituents. 2. Effects of exercise and diet on variation of serum constituents in healthy subjects, Clin. Chem., 19, 1380, 10.1093/clinchem/19.12.1380

Poortmans, 1979, Biochemical changes in a 100 km run: proteins in serum and urine, Eur. J. Appl. Physiol. Occup. Physiol., 40, 245, 10.1007/BF00421516

Leonard, 1973, 134

Macy, 1993, Sample preparation for plasma measurement of plasminogen activator inhibitor-1 antigen in large population studies, Arch. Pathol. Lab. Med., 117, 67

Siest, 1981

Buckley, 1970, The effect of aging on human serum immunoglobulin concentrations, J. Immunol., 105, 964, 10.4049/jimmunol.105.4.964

Letellier, 1982, Study of seasonal variations for eighteen biochemical parameters over a four-year period, Clin. Biochem., 15, 206, 10.1016/S0009-9120(82)90112-6

Brohult, 1969, Effects of high protein and low protein diets on ornithine carbamoyl transferase activity in human serum (S-OCT), Acta Med. Scand., 185, 357, 10.1111/j.0954-6820.1969.tb07348.x

Linkowski, 1998, Genetic and environmental influences on prolactin secretion during wake and during sleep, Am. J. Physiol., 274, E909

Larina, 1992, The protein composition of the blood plasma of cosmonauts after prolonged orbital flights, Aviakosm. Ekolog. Med., 26, 67

Mendlewicz, 1999, Genetic control of 24-hour growth hormone secretion in man: a twin study, J. Clin. Endocrinol. Metab., 84, 856

Young, 1972, Effects of drugs on clinical laboratory tests, Clin. Chem., 18, 1041, 10.1093/clinchem/18.10.1041

Young, 1997, Effects of drugs on clinical laboratory tests, Ann. Clin. Biochem., 34, 579, 10.1177/000456329703400601

Jellum, 1981, Classification of human cancer cells by means of capillary gas chromatography and pattern recognition analysis, J. Chromatogr., 217, 231, 10.1016/S0021-9673(00)88077-2

Robertson, 1980, Biochemical individuality and the recognition of personal profiles with a computer, Clin. Chem., 26, 30, 10.1093/clinchem/26.1.30

Pankow, 2001, Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study, Atherosclerosis., 154, 681, 10.1016/S0021-9150(00)00586-4

Tarroux, 1983, Analysis of protein patterns during differentiation using 2-D electrophoresis and computer multidimensional classification, Electrophoresis., 4, 63, 10.1002/elps.1150040109

Anderson, 1984, Global approaches to quantitative analysis of gene-expression patterns observed by use of two-dimensional gel electrophoresis, Clin. Chem., 30, 2031, 10.1093/clinchem/30.12.2031

Anderson, 1987, Effects of toxic agents at the protein level: quantitative measurement of 213 mouse liver proteins following xenobiotic treatment, Fundam. Appl. Toxicol., 8, 39, 10.1016/0272-0590(87)90098-4

Anderson, 1996, The effects of peroxisome proliferators on protein abundances in mouse liver, Toxicol. Appl. Pharmacol., 137, 75, 10.1006/taap.1996.0059

Anderson, 1995, Effects of oltipraz and related chemoprevention compounds on gene expression in rat liver, J. Cell. Biochem. Suppl., 22, 108, 10.1002/jcb.240590814

Schmid, 1995, Lung tumor cells: a multivariate approach to cell classification using two-dimensional protein pattern, Electrophoresis., 16, 1961, 10.1002/elps.11501601322

Negishi, 1987, Clinical use of CA 125 and its combination assay with other tumor marker in patients with ovarian carcinoma, Gynecol. Obstet. Investig., 23, 200, 10.1159/000298862

Alaiya, 2000, Classification of human ovarian tumors using multivariate data analysis of polypeptide expression patterns, Int. J. Cancer., 86, 731, 10.1002/(SICI)1097-0215(20000601)86:5<731::AID-IJC20>3.0.CO;2-A

Young, 1995, Clinical applications of two-dimensional electrophoresis, J. Chromatogr. A., 698, 163, 10.1016/0021-9673(94)00988-L

Merril, 1995, The protein disease database of human body fluids: I. rationale for the development of this database, Appl. Theor. Electrophor., 5, 49

Garrels, 1996, YPD-A database for the proteins of Saccharomyces cerevisiae, Nucleic Acids Res., 24, 46, 10.1093/nar/24.1.46

Garrels, 2002, Yeast genomic databases and the challenge of the post-genomic era, Funct. Integr. Genomics., 2, 212, 10.1007/s10142-002-0061-7

Hodges, 2002, Annotating the human proteome: the Human Proteome Survey Database (HumanPSD) and an in-depth target database for G protein-coupled receptors (GPCR-PD) from Incyte Genomics, Nucleic Acids Res., 30, 137, 10.1093/nar/30.1.137

Specialty Laboratories (2001) Directory of Services, and Use and Interpretation of Tests, Santa Monica, CA

Harrela, 1996, Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3, J. Clin. Investig., 98, 2612, 10.1172/JCI119081

Verhaeghe, 1996, C-peptide, insulin-like growth factors I and II, and insulin-like growth factor binding protein-1 in cord serum of twins: genetic versus environmental regulation, Am. J. Obstet. Gynecol., 175, 1180, 10.1016/S0002-9378(96)70025-X

de Lange, 2001, The genetics of haemostasis: a twin study, Lancet., 357, 101, 10.1016/S0140-6736(00)03541-8

Kaprio, 2001, Heritability of leptin levels and the shared genetic effects on body mass index and leptin in adult Finnish twins, Int. J. Obes. Relat. Metab. Disord., 25, 132, 10.1038/sj.ijo.0801526

Bansal, 2000, Heritability of prostate-specific antigen and relationship with zonal prostate volumes in aging twins, J. Clin. Endocrinol. Metab., 85, 1272

Orstavik, 1990, Genetics of plasma concentration of von Willebrand factor, Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch., 117, 527

Boomsma, 1993, A parent-twin study of plasma levels of histidine-rich glycoprotein (HRG), Thromb. Haemostasis., 70, 848, 10.1055/s-0038-1649681

Daiger, 1984, Heritability of quantitative variation at the group-specific component (Gc) locus, Am. J. Hum. Genet., 36, 663

Jacobsen, 2001, IgE in unselected like-sexed monozygotic and dizygotic twins at birth and at 6 to 9 years of age: high but dissimilar genetic influence on IgE levels, J. Allergy Clin. Immunol., 107, 659, 10.1067/mai.2001.113565

Cesari, 1999, Determinants of plasma levels of plasminogen activator inhibitor-1: a study of normotensive twins, Arterioscler. Thromb. Vasc. Biol., 19, 316, 10.1161/01.ATV.19.2.316

Boomsma, 1993, Lipoprotein(a): relation to other risk factors and genetic heritability. Results from a Dutch parent-twin study, Atherosclerosis., 99, 23, 10.1016/0021-9150(93)90047-X

Smiles, 1998, Variability in plasma prothrombin concentration: implications for use in epidemiology, Blood Coagul. Fibrinolysis., 9, 525, 10.1097/00001721-199809000-00010

Valero-Politi, 1993, Within- and between-subject biological variations of follitropin, lutropin, testosterone, and sex-hormone-binding globulin in men, Clin. Chem., 39, 1723, 10.1093/clinchem/39.8.1723

Maes, 1995, Components of biological variation in plasma haptoglobin: relationships to plasma fibrinogen and immune variables, including interleukin-6 and its receptor, Clin. Chim. Acta., 239, 23, 10.1016/0009-8981(95)06094-T

Gonzalez, 2001, Biological variation of interleukin-1β, interleukin-8 and tumor necrosis factor-α in serum of healthy individuals, Clin. Chem. Lab. Med., 39, 836, 10.1515/CCLM.2001.139