The Experimental and Commercial Release of Transgenic Crop Plants

Plant Breeding - Tập 111 Số 1 - Trang 1-22 - 1993
Phillip J. Dale1, Judith A. Irwin1, Jodi Scheffler1
1AFRC Institute of Plant Science Research, Cambridge Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UJ, England.

Tóm tắt

AbstractWith advances in recombinant DNA methods and transformation procedures, it is possible to transfer genes into crop plants from unrelated plants, microbes and animals. Many of the modifications being carried out, or envisaged, are for disease and pest resistance, product quality and tolerance to environmental stress, but there are additional opportunities to modify crops to give specialized products for industrial or pharmaceutical use. Some of the characteristics of transgenic plants are considered, including: transgene copy number, position, expression, stability, pleiotropy, selectable marker genes and somaclonal variation. There have been several hundreds of field trials with transgenic plants, and the first transgenic varieties are likely to be approved for commercial production in 1993. Before releasing transgenic plants, it is necessary to carry out a risk assessment to determine whether the transgenic variety will behave differently from a conventionally bred variety. Assessment procedures are being harmonized internationally by various organizations. There is a growing commitment to apply these genetic modification methods to crops in developing countries, as genes relevant to their crops and environments become available.

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Tài liệu tham khảo

10.1007/BF00034952

10.1007/BF00293525

10.1139/g92-010

10.1007/BF00234297

10.1007/BF00193148

10.1111/j.1744-7348.1992.tb03403.x

Barry G. F. D. M.Stark Y. M.Muskopf R. E.McKinnie K. P.Timmerman andG. M.Kishore 1992:Improving potato quality through genetic engineering.Amer. Soc. Agron. Abstr.187.

10.1007/BF00034962

10.1007/BF00226910

10.1007/BF00017925

10.1177/003072708901800101

10.1126/science.254.5035.1194

10.1146/annurev.py.07.090169.002035

10.1016/0167-7799(92)90243-O

Calgene 1990:Kan' Gene: Safety and Use in the Production of Genetically Engineered Plants Request for Advisory Opinion. Calgene inc. California USA.

10.1007/BF00231834

Caseley J. C., 1991, Herbicide Resistance in Weeds and Crops

Chasseray E., 1992, Field trials of transgenic plants: an overview, Agro Food Industry Hi Tech., 3, 5

10.1007/BF00232293

Chen Z.‐L. 1992:Field releases of recombinant bacteria and transgenic plants in China. In:R.CasperandJ.Landsmann (eds.)Proc. 2nd Int. Symp. Biosafety Results of Field Tests of Genetically Modified Plants and Microorganisms 53. Biol. Bundesanstalt für Land‐ und Forstwirtschaft Braunschweig Germany.

10.1111/j.1399-3054.1990.tb05889.x

10.1038/nbt1091-957

10.1073/pnas.84.12.3962

10.1038/nbt0589-503

10.1007/BF00330188

Crawley M. J. 1992:The comparative ecology of transgenic and conventional crops. In:R.CasperandJ.Landsmann (eds.) Proc. 2nd Int. Symp. Biosafety Results of Field Tests of Genetically Modified Plants and Microorganisms 43–52. Biol. Bundesanstalt für Land‐ und Forstwirtschaft Braunschweig Germany.

10.1105/tpc.4.12.1495

10.1038/nbt0392-309

10.2135/cropsci1990.0011183X003000040020x

10.1007/BF00231834

10.1104/pp.100.1.13

10.1007/BF00224156

Dale P. J. R.Parkinson G. R.MacKay andJ. A.Scheffler 1992:Gene dispersal from transgenic crops by pollen. In:R.CasparandJ.Landsmann (eds.) Proc. 2nd Int. Symp. Biosafety Results of Field Tests of Genetically Modified Plants and Microorganisms 73–78. Biol. Bundesanstalt für Land‐ und Forstwirtschaft Braunschweig Germany.

10.1038/nbt0890-736

10.1007/BF00239102

10.1002/j.1460-2075.1987.tb02537.x

10.1104/pp.91.2.694

10.1007/BF02190610

10.1038/nbt0189-61

DeVries F. T. R.Van derMeijden andW. A.Brandenburg 1992:Botanical Files — a study of the real chances for spontaneous gene flow from cultivated plants to the wild flora of the Netherlands. Gorteria Supplement Netherlands Ministry of Housing Physical Planning and Environment Leidschendam.

Delannay X., 1989, Field performance of transgenic tomato plants expressing the Bacillus thuringiensis var Kurstaki insect control protein, Biotechnology, 7, 1265

10.1038/nbt0991-858

10.1038/nbt0193-84

10.1038/nbt1187-1201

10.1007/BF00333574

10.1007/BF00270059

10.1038/nbt0887-807

10.1038/nbt1192-1466

10.1007/BF00237128

10.1038/nbt0292-141

10.1038/nbt0192-40

Fraley R. T., 1988, Current Communications in Molecular Biology: Improvement of Agriculturally Important Crops, 83

10.1038/nbt0990-833

10.1038/scientificamerican0692-62

Glickman T. S., 1990, Readings in risk. Resources for the future, 1

10.1038/nbt1292-1562

Gould F., 1988, Genetic engineering, integrated pest management and the evolution of pests, Tib-tech, 6, S15

Gould F., 1991, The evolutionary potential of crop pests, Amer. Sci., 79, 496

10.1073/pnas.89.17.7986

10.1016/0168-9452(87)90112-9

10.1007/BF00259393

10.1104/pp.86.2.602

10.1007/BF00037141

10.1038/nbt0491-373

Hills M. J., 1991, Biotechnology and Genetic Engineering Reviews, 1

10.1038/nbt0888-915

10.1007/BF00039425

10.1007/BF00272733

10.1126/science.223.4635.496

10.1007/BF00019396

Jenkins J. N., 1991, Field test of transgenic cottons containing a Bacillus Thuringiensis gene, Tech. Bull. Mississippi Agric. For. Expt. Stat., 174, 1

10.1016/0167-7799(92)90205-A

10.1007/BF00330861

10.1038/nbt0492-422

10.1007/BF00272543

Jorgensen R., 1993, Silencing of plant genes by homologous transgenes

10.1038/nbt0890-750

10.1177/000765039103000101

10.1139/x91-186

Knowlton S., 1988, Current Communications in Molecular Biology: Improvement of Agriculturally Important Crops, 55

10.1073/pnas.89.7.2624

10.1038/nbt0293-194

Krebbers E., 1991, GCIRC Eighth International Rapeseed Congress, 716

10.1007/BF02342540

10.1038/nbt0290-127

10.1007/BF00234294

Levin M., 1993, Overview of risk assessment and regulation of environmental biotechnology. Risk Assessment in Genetic Engineering

10.1093/jxb/41.5.529

10.1038/nbt0392-305

10.1038/nbt0991-864

10.1007/BF00027313

10.1104/pp.91.3.1020

10.1038/nbt0991-853

10.1038/347737a0

10.1038/357384a0

10.1002/j.1460-2075.1989.tb03421.x

10.1007/BF00015074

10.1007/BF00232339

10.1038/nbt0788-800

10.1007/BF00269045

McHughen A. M.Jordan andS.Mcsheffrey 1990:Two years of transgenic flax field tests: what do they tell usProc. VIIth Int. Congr. Plant Tissue and Cell Culture Amsterdam 207–212.

10.1007/BF00229510

10.1007/BF00292701

10.1007/BF00226744

Mitten D. H. M. K.Redenbaugh M.Sovero andM. G.Kramer 1992:Safety assessment and commercialization of transgenic fresh tomato food products transgenic cotton products and transgenic rapeseed oil products. In:R.CasperandJ.Landsmann (eds.) Proc. 2nd Int. Symp. Biosafety Results of Field Tests of Genetically Modified Plants and Microorganisms 179–184. Biol. Bun‐desanstalt für Land‐ und Forstwirtschaft Braunschweig Germany.

10.1007/BF00778542

Mukhopadyay A., 1991, Efficient regeneration of Brassica oleracea hypocotyl protoplasts and high frequency genetic transformation by direct DNA uptake, Plant Cell Rep., 10, 375

10.1038/nbt1190-1041

10.1038/356710a0

10.1007/BF02525165

10.1007/BF00233366

National Research Council USA, 1989, Field Testing Genetically Modified Organisms: Framework for Decisions

10.1007/BF00232854

10.1038/nbt0488-403

10.1007/BF00249138

10.1111/j.1399-3054.1990.tb05890.x

10.1007/BF00235264

10.1038/nbt1091-982

OECD 1986:Recombinant DNA Safety Considerations. Organization for Economic Co‐operation and Development Pans.

OECD 1990:Good developmental practices for small scale field research with genetically modified plants and microorganisms: a discussion document. Organization for Economic Co‐operation and Development Group of National Experts on Safety in Biotechnology.

Oelck M. M., 1991, GCIRC Eighth International Rapeseed Congress, 292

10.1038/nbt0592-561

10.1038/nbt1090-939

10.1126/science.256.5056.520

10.1111/j.1399-3054.1990.tb05874.x

10.1146/annurev.pp.42.060191.001225

10.1007/BF00224394

10.1007/BF00265588

10.1007/BF00236265

Raybould A. F. andA. J.Gray 1993:Genetically modified crops and their wild relatives — a UK perspective. United Kingdom Department of the Environment Publication. In Press.

10.1038/nbt0188-56

RoyalSociety 1992:Risk: analysis perception and management. Report of the Royal Society study group London. Published by Royal Society of UK.

10.1007/BF00272344

Sambrook J., 1989, Molecular cloning: a laboratory manual

10.1094/Phyto-82-683

Scheffler J. A. R.Parkinson andP. J.Dale 1993:Frequency and distance of pollen dispersal from transgenic oilseed rape (Brassica napus). Transgenic Res. In Press.

10.1007/BF00282454

10.1071/PP9910495

10.1146/annurev.ge.24.120190.003051

10.1073/pnas.85.23.8805

10.1007/BF00272967

10.1038/338274a0

10.1038/nbt0390-217

Slightom J. L. P. P.Chee andD.Gonsalves 1990:Field testing of cucumber plants which express the CMV coat protein gene: field plot design to test natural infection pressures. Proceedings of the VIIth International Congress on Plant Tissue and Cell Culture 201–206. Amsterdam.

10.1038/nbt1292-1589

10.1126/science.258.5080.287

10.1071/PP9910507

10.1038/nbt0889-811

Tarczynski M. C., 1991, Third Int. Congress of Plant Molecular Biology, 1517

10.1038/nbt0492-402

Thompson K. F., 1986, Oilseed Rape, 32

10.1104/pp.92.2.500

10.1007/BF00224988

Tormala T., 1992, Potential of biotechnology in floriculture, Agro-Food Industry Hi-Tech., 2, 5

Townsend J. A. L. A.Thomas E. S.Kulisek M. J.Daywalt K. R. K.Winter D. J.Grace W. J.Crook H. J.Schmidt T. C.Corbin andS. B.Altenbach 1992:Accumulation of a methionine‐rich brazil nut protein in seeds of transgenic soybean.Amer. Soc. Agron. Abstr.198.

Tynan J. L., 1990, Low frequency of pollen dispersal from a field trial of transgenic potatoes, J. Genet. and Breed., 44, 303

10.1007/BF00193143

10.1038/nbt0387-263

10.1093/jee/84.6.1943

UNIDO 1991:Voluntary code of conduct for the release of organisms into the environment. UNIDO/UNEP/WHO/FAO/working group on Biosafety.

USDA 1993:Record of environmental release permits to February 1993.US Department of Agriculture Animal and Plant Health Inspection Service Biotechnology Biologies and Environmental Protection Biotechnology Permit Unit 6505 Belcrest Road Hyattsville Maryland USA.

10.1007/BF00040637

10.1038/nbt0989-929

10.1038/nbt0692-667

10.1126/science.1621095

10.1038/nbt0692-691

Watson J. D., 1983, Recombinant DNA: A Short Course

10.1105/tpc.3.10.1121

Wolfe M. S., 1987, Populations of Plant Pathogens: Their Dynamics and Genetics

10.1146/annurev.ge.22.120188.000245